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A cross-sectional study in non-anaemic pregnant women in Turkey to assess necessity of iron supplementation
No full textBackground: Iron deficiency is the most common cause of anaemia in
pregnancy. Guidelines recommend different threshold values for iron
supplementation.
Aims: To determine trimester-specific reference ranges for
haematological values (haemoglobin, hematocrit and ferritin) in healthy
pregnant women who have not used any iron supplementation during
pregnancy to guide future iron treatment.
Methods: A prospective cross-sectional study was carried out on 168
pregnant women aged 18-45 years, with singleton pregnancies in the first
trimester, Hb >= 11 g/dL and ferritin >= 12 mu g/L, and not using iron
supplementation. Multiple pregnancies, pregnancies with obstetric
complications and smokers were excluded from the study. Mean haemoglobin
(Hb) and ferritin values, trimester-specific reference ranges and
percentile values of Hb and ferritin were determined for each trimester.
The normality of the variables was tested using the Kolmogorov-Smirnov
test.
Results: Mean Hb decreased significantly between trimesters from 12.6 to
11.9 and then 11.5 g/dL. In addition, Hb, hematocrit and ferritin
decreased significantly from the first to the second trimester (P <
0.001 for all) but stayed comparable between the second and third
trimesters (P = 0.246, P = 0.575, P = 0.408, respectively). The lower
reference value for Hb was calculated as 10.67, 10.08 and 9.18 g/dL for
10-14, 20-24 and 30-34 gestational weeks respectively.
Conclusion: This pioneer study allows us to understand that iron
supplementation may not be needed as any decrease is due to
physiological haemodilution. These results may prevent unnecessary iron
prescription during pregnancy
The inhibitory effects of isolated constituents from Plantago major subsp. major L. on collagenase, elastase and hyaluronidase enzymes: Potential wound healer
No full textProduction of Plastic Injection Molds with Conformal Cooling Channels by Laminated Brazing Method
No full textAISI 1050 çeliğin tornalanmasında kesme parametrelerinin yüzey pürüzlülüğü ve talaş oluşumu üzerine etkilerinin araştırılması
No full text
The effects of dexmedetomidine and ketamine on oxidative injuries and histological changes following blunt chest trauma
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Evaluation of thestatus quoof polyphenols analysis: Part I-phytochemistry, bioactivity, interactions, and industrial uses
No full textPhytochemicals, especially polyphenols, are gaining more attention from
both the scientific community and food, pharmaceutical, and cosmetics
industries due to their implications in human health. In this line,
lately new applications have emerged, and of great importance is the
selection of accurate and reliable analytical methods for better
evaluation of the quality of the end-products, which depends on diverse
process variables as well as on the matrices and on the physicochemical
properties of different polyphenols. The first of a two-part review on
polyphenols will address the phytochemistry and biological activities of
different classes of polyphenols including flavonoids, lignans and
flavanolignans, stilbenoids, tannins, curcuminoids, and coumarins.
Moreover, the possible interactions of polyphenols and current and
potential industrial applications of polyphenols are discussed
Internalized Stigma in Pediatric Psoriasis: A Comparative Multicenter Study
No full textBackground: Internalized stigma, adoption of negative attitudes and
stereotypes of the society regarding persons' illness, has not been
studied previously in pediatric psoriasis patients. Objective: We aimed
to investigate the internalized stigma in pediatric psoriasis patients
and to determine differences according to factors affecting internalized
stigma compared to adult psoriasis patients. Methods: This multicenter,
cross-sectional, comparative study included 125 pediatric (55 female, 70
male; mean age +/- standard deviation {[}SD], 14.59 +/- 2.87 years) and
1,235 adult psoriasis patients (577 female, 658 male; mean age +/- SD,
43.3 +/- 13.7 years). Psoriasis Internalized Stigma Scale (PISS),
Dermatology Life Quality Index (DLQI), Perceived Health Status (PHS),
and the General Health Questionnaire (GHQ)-12 were the scales used in
the study. Results: The mean PISS was 58.48 +/- 14.9 in pediatric group.
When PISS subscales of groups were compared, the pediatric group had
significantly higher stigma resistance (p = 0.01) whereas adult group
had higher scores of alienation (p = 0.01) and stereotype endorsement (p
= 0.04). There was a strong correlation between mean values of PISS and
DLQI (r = 0.423, p = 0.001). High internalized stigma scores had no
relation to either the severity or localization of disease in pediatric
group. However, poor PHS (p = 0.007) and low-income levels (p = 0.03) in
both groups, and body mass index (r = 0.181, p = 0.04) in the pediatric
group were related to high PISS scores. Conclusion: Internalized stigma
in pediatric patients is as high as adults and is related to poor
quality of life, general health, and psychological illnesses. Unlike
adults, internalized stigma was mainly determined by psoriasis per se,
rather than disease severity or involvement of visible body parts,
genitalia or folds