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The impact of the Russian vocal school on undergraduate level individual voice training acquisitions
No full textSes eğitimi sürecinde kullanılabilir nitelikte pek çok farklı şan ekolü bulunmakta ve bu süreçlerin söz konusu bu ekollerden etkilenerek şekillendiği bilinmektedir. Bu kapsamda İtalyan şan ekolünün yüzyıllardır önde gelen bir ekol olarak diğer ulusal şan ekollerinin gelişimini etkilediği; kendine özgü yoğun teknik eğitimi, vokal sağlamlığı ve ifade gücü ile öne çıkan Rus ekolü gibi farklı ekollerin de kullanıldığı görülmektedir. Bununla birlikte Türkiye’de ses eğitimi süreçlerinde genellikle İtalyan şan ekolünün benimsendiği bilinmekte; özellikle mesleki müzik eğitimi kapsamında ses eğitiminin önemi göz önüne alındığında bu alandaki yöntemlerin çeşitlendirilmesinin büyük önem taşıdığı düşünülmektedir. Bu düşünce ile bu araştırmada ses eğitimi sürecinde yaygın olarak kullanılan İtalyan şan ekolüne alternatif olarak Rus şan ekolünün öğretimsel katkılarının değerlendirmesi amaçlanmıştır. Araştırmada karma yöntem desenlerinden açıklayıcı sıralı desen kullanılmıştır. Nicel aşamada A-B modeliyle üç katılımcı üzerinde bireysel ses eğitimi uygulamaları gerçekleştirilmiş; nitel aşamada ise katılımcı görüşlerine başvurulmuştur. Veri toplama aracı olarak Nart ve Sulak (2018) tarafından geliştirilen Bireysel Ses Eğitimi Dereceli Puanlama Anahtarı ve araştırmacı tarafından hazırlanan yarı yapılandırılmış görüşme formu kullanılmıştır. Uygulama süreci Mikhail Glinka’nın vokal egzersizlerine dayalı olarak oluşturulan ders planları ile 15 hafta boyunca yürütülmüştür. Araştırmadan elde edilen bulgular doğrultusunda Rus şan ekolünün uygulandığı bireysel ses eğitimi derslerinin öğrencilerin vokal teknik, ifade ve performans becerilerini geliştirmede etkili olduğu sonuçlarına ulaşılmıştır. Ayrıca katılımcıların tamamı bu yöntemin nefes kontrolü, rezonans bölgelerini kullanma ve doğal ton üretimi açısından gelişimlerine katkı sağladığını belirtmişlerdir. Elde edilen bulgular Rus şan ekolünün Türkiye’deki ses eğitimi süreçlerinde alternatif ve etkili bir yaklaşım olarak değerlendirilebileceğini ortaya koymaktadır.There are many different singing schools that can be effectively used in the voice training process, and it is known that these processes are shaped under the influence of such schools. İn this context, the İtalian singing school has long been recognized as a leading school that has influenced the development of other national vocal traditions; at the same time, schools with distinct characteristics-such as the Russian school, known for its intensive technical training, vocal solidity, and expressive power-are also utilized. However, it is known that the İtalian singing school is predominantly adopted in voice training practices in Türkiye; considering the importance of voice training especially within the scope of professional music education, diversifying the methods used in this field is regarded as highly significant. With this in mind, the present study aimed to evaluate the instructional contributions of the Russian singing school as an alternative to the commonly used İtalian school within the voice training process. An explanatory sequential design, one of the mixed-method research designs, was employed. İn the quantitative phase, individual voice training practices were conducted with three participants using the A-B model; in the qualitative phase, participant views were obtained. As data collection tools, the İndividual Voice Training Rubric developed by Nart and Sulak (2018) and a semi-structured interview form prepared by the researcher were used. The implementation process was carried out over 15 weeks with lesson plans based on Mikhail Glinka’s vocal exercises. According to the findings obtained from the study, individual voice training lessons in which the Russian singing school was applied were found to be effective in improving students’ vocal technique, expression, and performance skills. İn addition, all participants stated that this method contributed to their development in terms of breath control, use of resonance areas, and natural tone production. The findings suggest that the Russian singing school can be considered an alternative and effective approach within voice training processes in Türkiye
The effect of skill-based activities in the 2024 curriculum on prospective teachers' misconceptions about electrochemistry
No full textBu araştırmada, 2024 yılında yayınlanan Türkiye Yüzyılı Maarif Modeli’nin ortak metninde yer alan fen bilimleri alanına özgü becerileri setleri ve süreç bileşenleri rehberliğinde farklı beceri temelli etkinlikler içeren öğrenme-öğretme faaliyetleri planlanmıştır. Bu planlanan etkinliklerinin fen bilimleri öğretiminde eğitim alan 26 öğretmen adayının alanyazında genellikle ‘’Elektrokimya’’ olarak geçen, yeni kimya öğretim programında ise‘’Kimya ve Elektrik’’ adında yer alan konudaki kavram yanılgılarına etkisi incelenmiştir. Çalışma kapsamında deneysel araştırmalardan biri olan ön test-son test yarı deneysel desen kullanılmıştır. Araştırma, 2024-2025 öğretim yılında, Bursa Uludağ Üniversitesi Eğitim Bilimleri Enstitüsü Matematik ve Fen Bilimleri Anabilim Dalı Fen Bilgisi Eğitimi bölümünde 1.sınıfta öğrenim gören 26 öğretmen adayı ile çalışılmıştır. Araştırmacı tarafından planlanan farklı etkinlik türlerin kavramsal anlama düzeyi ve kavram yanılgılarına etkisini Şen (2015) tarafından geliştirilmiş ‘’Elektrokimya Kavram Testi’’ adlı 3 aşamalı kavram testi gerekli izin alınıp ön test- son test ölçme aracı olarak kullanılmıştır. Araştırma kapsamında, son test sonuçları incelendiğinde bilgi eksikliği oranında azalma, bilimsel bilgi oranında artma olmasına rağmen kavram yanılgılarının tümüyle giderilmediği görülmüştür. Araştırmada elde edilen bulgular kapsamlı bir şekilde analiz edilerek gelecekteki araştırmalara ve öğretmenlere yönelik çeşitli önerilerde bulunulmuştur.In this research, learning-teaching activities that include different types of activities were planned under the guidance of process components that are claimed to develop science-specific skills in the common text of the Türkiye Century Education Model published in 2024. The effects of these planned activities on the misconceptions of 26 prospective science teachers on the subject, which is generally referred to as "Electrochemistry" in the literature but is called "Chemistry and Electricity" in the new chemistry curriculum, were examined. Within the scope of the study, a pretest-posttest quasi-experimental design, one of the experimental researches, was used. The research was conducted with 26 first-year pre-service teachers studying in the Science Education Department of th at Bursa Uludağ University in the 2024-2025 academic year. The three-stage concept test called "Electrochemistry Concept Test," developed by Şen (2015) to detect misconceptions in order to determine the effects of different activity types planned by the researcher on the level of conceptual understanding and misconceptions, was used as a pretest-posttest measurement tool after obtaining the necessary permissions. The analysis of the post-test results indicated a decrease in the rate of lack of knowledge and an increase in the rate of scientific knowledge, although misconceptions were not completely eliminated.The findings of the study were comprehensively analyzed, and various recommendations were made for future research and for teachers
The relationship between health and sustainable development: An analysis through the burden of non-communicable diseases
No full textSon yüzyılda gerçekleşen bilimsel, teknolojik ve sosyoekonomik ilerlemeler; eğitim, beslenme, barınma, su ve sanitasyon koşullarındaki iyileşmelerle birlikte sağlık alanında köklü dönüşümler yaratmıştır. Bu gelişmeler, bulaşıcı hastalıklarla mücadelede önemli başarılar sağlamış ve doğumda beklenen yaşam süresini belirgin biçimde artırmıştır. Ancak yaşam süresindeki artış, hastalık ve ölüm nedenlerinde yapısal bir değişimi de beraberinde getirmiştir. “Epidemiyolojik geçiş” olarak tanımlanan bu süreçte, bulaşıcı hastalıkların yerini giderek kardiyovasküler hastalıklar, kanser, kronik solunum yolu hastalıkları ve diyabet gibi bulaşıcı olmayan hastalıklar (BOH) almıştır. BOH’lar, uzun süreli morbiditeye ve mortaliteye yol açarak yaşam kalitesini düşürmekte; üretkenlik kaybı ve artan sağlık maliyetleriyle ekonomik ve sosyal sistemlere büyük yük getirmektedir. Bu durum, özellikle düşük ve orta gelirli ülkelerde eşitsizlikleri derinleştirerek sürdürülebilir kalkınmayı ciddi biçimde tehdit etmektedir. Bu nedenle, BOH’ların toplam hastalık yükünün sürdürülebilir kalkınma üzerindeki etkilerinin incelenmesi önem taşımaktadır. Bu çerçevede çalışmanın temel amacı, bulaşıcı olmayan hastalıklardan kaynaklanan toplam hastalık yükünün sürdürülebilir kalkınma üzerindeki etkilerini nicel yöntemlerle analiz ederek, sağlık ile kalkınma arasındaki ilişkiyi ortaya koymaktır. Çalışmada, Dünya Bankası’nın alt-orta ve üstorta gelir gruplarının toplamı olarak sınıflandırdığı gelişmekte olan ülkelerden oluşan bir örneklem kullanılmıştır. Bu örneklemden sağlanan 2002–2021 dönemine ait yıllık verilerle dinamik panel veri analizi gerçekleştirilmiştir. Ampirik analizde bağımlı değişken olarak Hickel’in Sürdürülebilir Kalkınma Endeksi (SDI) kullanılmıştır. Sürdürülebilir kalkınmayı açıklamak için temel bağımsız değişken olarak BOH kaynaklı Engelliliğe Ayarlanmış Yaşam Yılları (DALY) göstergesi tercih edilmiş; modelin gücünü artırmak için ise sosyoekonomik, demografik ve çevresel kontrol değişkenleri modele dahil edilmiştir. Analiz çerçevesinde gerçekleştirilen dinamik Sistem GMM tahminleri, BOH kaynaklı DALY’nin sürdürülebilir kalkınma üzerinde istatistiksel açıdan anlamlı ve negatif bir etkiye sahip olduğunu ortaya koymuştur. Bulgular, BOH’ların yol açtığı sağlık kayıplarının bireysel ve toplumsal düzeyde olumsuz etkiler yarattığını ve uzun vadede sürdürülebilir kalkınmayı zayıflattığını göstermiştir. Bu sonuçlar, özellikle gelişmekte olan ülkelerde BOH önleme stratejilerinin kalkınma politikalarına entegre edilmesinin zorunluluğuna işaret etmiştir.Scientific, technological, and socioeconomic advances over the past century, combined with improvements in education, nutrition, housing, water, and sanitation, have brought about fundamental transformations in health. These developments have led to significant successes in combating infectious diseases and have markedly increased life expectancy at birth. However, the increase in life expectancy has also brought about a structural change in the causes of illness and death. In this process, defined as the “epidemiological transition,” infectious diseases have increasingly been replaced by noncommunicable diseases (NCDs) such as cardiovascular diseases, cancer, chronic respiratory diseases, and diabetes. NCDs reduce quality of life by causing long-term morbidity and mortality; they also place a heavy burden on economic and social systems through lost productivity and increased healthcare costs. This situation seriously threatens sustainable development, particularly by deepening inequalities in low- and middle-income countries. Therefore, it is important to examine the impact of the total disease burden of NCDs on sustainable development. Within this framework, the main objective of the study is to analyze the effects of the total disease burden caused by noncommunicable diseases on sustainable development using quantitative methods, thereby revealing the relationship between health and development. The study utilized a sample comprising developing countries classified by the World Bank as the sum of lower-middle and upper-middle income groups. A dynamic panel data analysis was performed using annual data from the 2002–2021 period obtained from this sample. In the empirical analysis, Hickel’s Sustainable Development Index (SDI) was used as the dependent variable. The Disability-Adjusted Life Years (DALY) indicator derived from the BOH was used as the primary independent variable to explain sustainable development; socio-economic, demographic, and environmental control variables were included in the model to increase its power. Dynamic System GMM estimates conducted within the framework of the analysis revealed that NCD-related DALY has a statistically significant and negative impact on sustainable development. The findings show that health losses caused by NCDs create negative effects at the individual and societal levels and weaken sustainable development in the long term. These results point to the necessity of integrating NCD prevention strategies into development policies, especially in developing countries
Clinical, histopathological, and immunohistochemical investigations of the Effects of Aloe Vera (Aloe barbadensis Miller) on open wound healing in rats
No full textThe aim of this study was to investigate the efficacy of freshly prepared (from the freeze-dried powder form) solution of Aloe barbadensis Miller on experimentally induced excisional wounds in rats. Eighty female Sprague Dawley rats were divided into ten groups: control, Madecassol® pomade, Carravet® gel, and different concentrations of the solution form of Aloe vera. Bilateral excisional wounds were created on both the right and left sides of the dorsal midline. All drugs were applied topically for 21 days, wounds were observed daily, and biopsies were taken on days 7, 14, and 21. Inflammatory cell count, vascularization, VEGF, and TGF-β1 levels were investigated. Biomechanical evaluations were also performed in a stretching device by using skin samples taken on day 21 after ending the study. Wounds in the 1% Aloe vera group closed earlier than in the control group. Wounds applied with Aloe vera had lower inflammatory cell counts and a higher degree of neovascularization when compared with the wounds applied with Madecassol® pomade and Carravet® gel. TGF-β1 levels decreased gradually only in the control group, while VEGF levels in the 2.5 and 10% Aloe vera groups were significantly higher than in the other groups on day 21. The 10% Aloe vera group had a higher tensile strength than other groups. As a conclusion, the solution form of Aloe vera is more effective than the gel form in wound healing. Notably, the 1% concentration of Aloe vera solution can be a potential wound healing agent
Hemp-derived iron oxide nanoparticles for biomedical applications: Synthesis, characterization, and therapeutic potential
No full textIron oxide nanoparticles (IONPs) have emerged as the most widely synthesized metal nanoparticles in sustainable chemistry due to their unique magnetic properties, excellent biocompatibility, biodegradability, and non-toxicity. In this study, IONPs are successfully synthesized via a rapid, sustainable, and environmentally friendly green synthesis approach using Cannabis sativa L. leaf extract. X-ray diffraction analysis determined that the synthesized NPs had an average particle size of 18.8 nm, while transmission electron microscopy images reveal a spherical morphology with sizes ranging from 12 to 21 nm. Fourier-transform infrared spectroscopy analysis confirmed the presence of cannabinoids, terpenoids, and flavonoids, which are believed to play a crucial role in the formation and stabilization of IONPs. Its photocatalytic potential is demonstrated through the degradation of bromophenol blue dye. Additionally, the NPs exhibited significant antibacterial and antifungal activity against various microbial species, along with promising anticancer effects on cancer cell lines. In conclusion, this study provides a promising foundation for advancing the large-scale, commercial production of IONPs through green synthesis methods. By offering an eco-friendly and efficient alternative to conventional nanoparticle synthesis, the findings contribute significantly to the growing body of research in sustainable nanotechnology
Diet-gut microbiome nexus: A new paradigm in food-based mental disease therapeutics
No full textMental health and well-being are greatly influenced by interactions between gut microbiota and the brain. This "gut microbiome-brain axis" (GMBA) operates through the various metabolic products released by gut microbes, which can be altered by diet changes. Additional research is needed to elucidate the association among diet, microbial constitution, metabolite production, and various neurological and neurodegenerative conditions. This article abridges the current understanding of microbiota-mediated mental pathogenesis, opportunities for non-invasive diagnosis, and treatment options utilizing GMBA modulations. Research on the interactions between diet, microbiota, and the brain has revealed that nutritional therapy could be a promising approach for preventing or treating depression, anxiety, and neurodegenerative diseases. Studies show that the gut microbiota regulates neurological pathways, endocrine signaling, tryptophan metabolism, gut-brain communication, and immune responses. The consumption of dietary components like prebiotics, probiotics, and pharmaceutical products can modify the gut microbiota, influencing mental health and well-being. Moreover, both psychiatric and non-psychiatric neurodegenerative disorders, as well as bacterial infections, play a critical role in maintaining gut microbiota and affecting mental health. As a result, there is potential to develop innovative functional foods, supplements, or medicines tailored to support a gut microbiome that promotes better mental health
Lightweight design and structural analysis of a bi-articulated bus: Experimental measurements and fem validation
No full textThe concept of sustainability prioritizes energy efficiency, especially in transportation, which directly impacts environmental sustainability. This study presents, for the first time, the lightweight design and structural performance of a 25-meter, three-section, double-articulated bus body frame through a hybrid methodology that integrates experimental road data with finite element (FE) validation. A finite element model was created and analyzed under various conditions. Lightweighting studies were performed using topology optimization, design modifications, and different materials. Data from real road conditions were collected and compared with simulation results, achieving up to 93% correlation at specific points. As a result, a 14.1% weight reduction was achieved in the bus body frame without compromising safety or passenger capacity. This lightweighting contributes significantly to sustainable transportation by reducing emissions over the vehicle's lifetime
The principle of equality of arms in criminal procedure law
No full textBu çalışmada, ceza muhakemesi hukukunda silahların eşitliği ilkesinin normatif temelleri, tarihsel arka planı ve uygulamadaki yansımaları kapsamlı biçimde incelenmiştir. Adil yargılanma hakkının asli unsurlarından biri olan bu ilke, yalnızca taraflara eşit usuli haklar tanınması değil, aynı zamanda bu hakların etkili şekilde kullanılabilmesini de güvence altına almayı amaçlamaktadır. Çalışmanın temel amacı, silahların eşitliği ilkesinin ceza yargılamasındaki yapısal işlevini bütüncül biçimde analiz ederek, gerek kuramsal gerek içtihadi düzeyde ilkenin kapsamını ve sınırlarını ortaya koymaktır. Araştırma üç bölümden oluşmaktadır. İlk bölümde, ilkenin hukuki, tarihi ve felsefi temelleri ele alınmış; Avrupa İnsan Hakları Mahkemesi ve Anayasa Mahkemesi içtihatları doğrultusunda adil yargılanma hakkı ile olan ilişkisi analiz edilmiştir. Bu kapsamda ayrıca, özgürlük ve güvenlik hakkı, kabahatler hukuku ve ceza muhakemesi sistemleri bağlamında silahların eşitliği ilkesinin yeri ve işlevi de ayrıntılı biçimde değerlendirilmiştir. İkinci bölümde, ilkenin ceza muhakemesi sürecindeki somut görünümleri incelenmiş; dosyaya erişim, delillere karşı itiraz ve delil toplama süreçlerinde taraflar arasında işleyen dengenin ne şekilde kurulduğu ya da bozulduğu örnek olaylar ve içtihatlar üzerinden değerlendirilmiştir. Üçüncü bölümde ise, asgari sanık hakları bağlamında silahların eşitliği ilkesinin işlevselliği tartışılmış; müdafi yardımından yararlanma, isnadı öğrenme, tercüman desteği ve tanık sorgulama gibi hakların kullanımına ilişkin yargı uygulamaları, AİHM ve AYM kararları ışığında kapsamlı biçimde analiz edilmiştir. Çalışmada, normatif analiz yöntemi esas alınmış; AİHM ve AYM içtihatları, öğretideki görüşlerle birlikte değerlendirilerek eleştirel bir çözümleme yapılmıştır. Sonuç olarak, silahların eşitliği ilkesinin yalnızca usuli bir araç değil, yargılamanın meşruiyetini ve tarafsızlığını sağlayan yapısal bir ilke olduğu sonucuna varılmış; ilkenin uygulanabilirliğini güçlendirecek düzenleme ve uygulama önerilerine yer verilmiştir.This study examines the principle of equality of arms in criminal procedure law by analyzing its normative foundations, historical development, and practical implications. As a fundamental element of the right to a fair trial, the principle ensures not only formal procedural equality but also the effective use of procedural rights. The research aims to provide a comprehensive analysis of its structural role and define its scope and boundaries in theory and case law. The thesis comprises three chapters. The first explores the legal, historical, and philosophical bases of the principle, with reference to ECtHR and Turkish Constitutional Court case law. It also addresses the principle’s function in relation to the right to liberty and security, misdemeanour law, and criminal justice models. The second chapter focuses on the principle’s application during the trial process, including access to the case file, evidentiary challenges, and procedural fairness. The third chapter evaluates its role in securing minimum defence rights such as legal assistance, notice of charges, interpretation, and witness examination. The study adopts a normative-analytical methodology, critically engaging with ECtHR and Turkish Constitutional Court case law in conjunction with doctrinal perspectives. Ultimately, it concludes that the principle of equality of arms should not be regarded as a mere procedural formality, but rather as a structural guarantee that safeguards both the legitimacy of the criminal process and the impartiality of the judiciary. Accordingly, the study proposes a set of reforms aimed at reinforcing the practical effectiveness of the principle
Monitoring of immunoglobulin treatment compliance of patients with an inborn error of immunity during the pandemic period
No full textBackgroundDuring the coronavirus disease 2019 (COVID-19) pandemic, significant challenges have been encountered in managing patients with chronic diseases. This study aimed to evaluate the effects of the pandemic on follow-up and treatment adherence in patients receiving immunoglobulin replacement therapy (IRT).MethodsA study examining the changes in IRT application methods was conducted between March 2020 and September 2021. An online message line, under the control of nurses and doctors, was established for our patients, and their usage rates for this communication system were recorded.ResultsA total of 169 patients, 93 males and 76 females, were included in the study. Among the patients, 124 (73.4%) received intravenous immunoglobulin (IVIG), and 45 (26.6%) received subcutaneous immunoglobulin (SCIG) treatment. Male sex was more common in both the IVIG and SCIG groups. Although all patients in the subcutaneous treatment group continued the treatments regularly, this rate was 80.6% in the IVIG group. During the pandemic, 26 patients switched from IVIG to SCIG treatment. Furthermore, 24 patients interrupted immunoglobulin treatment for various reasons. Patients who received subcutaneous treatment took a long break from their hospital controls, although they applied them properly at home. Routine immunoglobulin trough values were measured in only 17 (37.7%) patients who were on SCIG. In the presence of symptoms, 100% of SCIG patients contacted the remote medical team via the online message line, compared to 48.3% of IVIG patients.ConclusionDuring the pandemic, the route of immunoglobulin treatment should be individualized based on each patient's characteristics and expectations. Telehealth services have emerged as a crucial tool for monitoring patients with chronic disorders, facilitating effective communication and personalized care.British Society for Allergy and Immunolog
First record of the spider genus hellamalthonica bosmans, 2023 (araneae, agelenidae) from turkiye, with the description of a new species
No full textBackground The spider genus Hellamalthonica Bosmans, 2023 of the family Agelenidae currently contains five species and all species are known from Greece. This genus has not been recorded in Turkiye yet. New information A new species, Hellamalthonica kazdagensis sp. nov., is described (male female) from Mount Kaz Da & gbreve;& imath;, Bal & imath;kesir Province, Turkiye. This is also the first report of Hellamalthonica in Turkiye. Morphological descriptions, photomicroscopy and Scanning Electron Microscopy (SEM) images of the new species, a key to all species of the genus and a distribution map of Hellamalthonica species are given