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    Yapay Zekâ Destekli Reklam Filmlerinde Toplumsal Cinsiyetin Göstergebilimsel Temsili

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    Reklamcılık alanında dijital teknolojilerin entegrasyonu, yaratıcı üretim süreçlerini köklü biçimde dönüştürmüştür. Yapay zekâ destekli sistemler, insan sezgisiyle makine öğrenmesini birleştirerek hem estetik hem de stratejik karar süreçlerinde yeni bir yaratıcılık biçimi ortaya koymaktadır. Bu bağlamda reklam, yalnızca teknik bir üretim alanı değil, aynı zamanda kültürel ve toplumsal anlamların yeniden üretildiği bir temsil mecrası haline gelmiştir. Bu çalışma, yapay zekâ destekli “Bizim Evler 11” reklam filminde toplumsal cinsiyet temsillerinin incelenmesini amaçlamaktadır. Araştırmada Roland Barthes’ın üç düzeyli göstergebilimsel analiz modeli (düz anlam, yan anlam, mit) kullanılarak reklamın görsel, işitsel ve dilsel göstergeleri çözümlenmiştir. Analiz, toplumsal cinsiyetin kültürel bir inşa olduğu ve medya aracılığıyla sürekli yeniden üretildiği varsayımına dayanmaktadır. Elde edilen bulgular, reklamda kadın ve erkek temsillerinin geleneksel kalıpların ötesinde, tamamlayıcı ve eşitlikçi bir biçimde sunulduğunu göstermektedir. “Bakkal amca” ve “şekerci teyze” karakterleri aracılığıyla her iki cinsiyetin kamusal alanda aktif biçimde temsil edildiği; kadınların yalnızca bakım veren değil, üretken ve sosyal ilişkilerin kurucu öznesi olarak yansıtıldığı görülmüştür. Erkek karakterler ise otoriter kimliklerinden uzaklaşarak sevgi, babalık ve paylaşım gibi duygusal yönleriyle öne çıkmaktadır. Çocukların cinsiyet ayrımı olmaksızın birlikte oyun oynaması, eşitlik ve aidiyet duygusunu pekiştirmektedir. Sonuç olarak, “Bizim Evler 11” reklam filmi modernleşme ve gelenek arasında duygusal bir denge kurarak cinsiyet eşitliğini kültürel bir uzlaşı anlatısı içinde yeniden tanımlamaktadır. Yapay zekâ destekli bu üretim biçimi, teknolojik yeniliği toplumsal temsillerin dönüşümüyle ilişkilendirerek, reklamcılıkta yeni bir estetik ve ideolojik paradigma sunmaktadır.The integration of digital technologies into the field of advertising has profoundly transformed creative production processes. AI assisted systems combine human intuition with machine learning, generating a new form of creativity that influences both aesthetic and strategic decision making. In this context, advertising is not merely a technical domain of production but also a medium through which cultural and social meanings are continuously reconstructed. This study aims to examine the representations of gender in the AI assisted commercial “Bizim Evler 11.” The research employs Roland Barthes’ three level semiotic analysis model denotation, connotation, and myth to interpret the visual, auditory, and linguistic signs within the advertisement. The analysis is grounded in the assumption that gender is a cultural construct that is continually reproduced through media representations. The findings reveal that the representations of women and men transcend traditional patterns and are presented in a complementary and egalitarian manner. Through the figures of the “grocery man” (bakkal amca) and the “candy woman” (şekerci teyze), both genders are actively represented within the public sphere. Women are depicted not merely as caregivers but also as productive agents and central figures in social relations. Male characters, on the other hand, move away from authoritative portrayals and are foregrounded through themes of affection, fatherhood, and emotional sharing. The depiction of boys and girls playing together without gender distinction reinforces a sense of equality and belonging. In conclusion, the “Bizim Evler 11” commercial establishes an emotional balance between modernity and tradition, redefining gender equality within a narrative of cultural reconciliation. This form of AI enhanced production links technological innovation with the transformation of social representations, presenting a new aesthetic and ideological paradigm in contemporary advertising.</p

    Chronological age estimation by measuring pulp chamber volume in teeth with open apices: A CBCT analysis

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    BACKGROUND: In the domain of forensic medicine, the estimation of age is a critical aspect of human identification, including that of adolescents. OBJECTIVES: The study aimed to examine the relationship between the pulp chamber volume of teeth with open apices and the chronological age of adolescents from the Turkish population. MATERIAL AND METHODS: The study was conducted by examining cone beam computed tomography (CBCT) images of 51 pediatric patients who visited the Department of Pedodontics for routine dental examinations. All CBCT images were captured using a NewTom 5G unit (QR, Verona, Italy). The measurements were recorded in DICOM format using the SimPlant Pro 16 software (Materialise NV, Leuven, Belgium). RESULTS: A moderate and positive significant correlation was observed between the age of the premolar group patients and impacted pulp volume (IMPV). The increase in volume measurements of the patients in the premolar group indicates that their age is significantly higher (r = 0.561, p = 0.030). A moderate and negative significant relationship was identified between the age of the premolar group patients and erupted pulp volume (EPV). The increase in the EPV measurements of the patients in the premolar group indicates that their age is significantly lower (r = -0.491, p = 0.041). CONCLUSIONS: The pulp chamber volume of premolars, which narrows due to secondary dentin deposition, served as the physical marker for chronological age estimation of adolescents in the Turkish population. The measurement of the mature and immature premolar pulp volume could be used for age estimation, particularly in the context of CBCT analysis

    Synthesis, biological evaluation, molecular modeling, and DFT calculations of novel quinoline-conjugated sulfonyl hydrazones as potential anticancer agents

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    Despite early diagnosis and advanced treatment options, cancer remains a serious public health threat, especially breast cancer, which presents a high risk of death and significant challenges for women. In this study, we report the design and synthesis of new quinoline-containing sulfonyl hydrazones (QSH1-QSH15) as potential cytotoxic agents. The compounds were obtained through the reaction of various benzaldehydes with quinoline-8sulfonohydrazide, which was in-house prepared from quinoline-8-sulfonyl chloride and an excess amount of hydrazine hydrate. Following structural analysis, QSH1-QSH15 were examined for their potential to inhibit the growth of human breast cancer cell lines MCF-7 and MDA-MB-231. The results from the MTT assay revealed that lipophilic chlorine and fluorine atoms positioned particularly at the ortho or meta-position of the terminal phenyl ring were favored substituents on the quinoline-sulfonyl hydrazone scaffold for cytotoxic activity. Three compounds with the lowest IC50 values against MDA-MB-231 cell line (QSH6, QSH8, and QSH14) were examined for their impact on the apoptotic pathway. Additionally, evaluating significant parameters for drug-likeness and pharmacokinetic profile demonstrated the suitability of selected compounds for drug development against breast cancer. Molecular docking and molecular dynamics simulations indicated that this class of molecules may function by inhibiting cyclin-dependent kinase 2 (CDK2) as their potential mechanism of action. Finally, DFT studies for these three compounds (QSH6, QSH8, and QSH14) were carried out by density functional theory using B3LYP level with the 6-31+G(d,p) basis set

    Implementing ANFIS with Three-Layer Architecture for Time Series

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    The complex time addiction and randomness of multivariate time series make it nec-essary to apply time series analysis to these variables. So, it is important to produce methods that can be used appropriately for time series system identification. Time series are generally handled as a single-layer architecture consisting of only the observed data processing layer. In this study, a hybrid method has three-layer adapted and evaluated using an adaptive neuro-fuzzy inference system (ANFIS). The main motivation of this study is to learn the errors produced by ANFIS method and to use them as new in-formation. For this purpose, proposed method was evaluated using real-time serial data sets obtained from different fields. Due to the three-layer architecture, the errors caused by the results produced by ANFIS are reused. As a result, the method of learning from errors has been realized and better results have been produced com-pared to traditional single-layer architecture.</jats:p

    Kent Dindarlığı: Anlam Merkezli Bir Çözümleme

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    Modernleşmenin hızlandığı, kimliklerinakışkanlaştığı, tüketim kültürünün yaygınlaştığı kentlerde bütün diğer yapılargibi dindarlık da artık eski formlarına sığmıyor: bireyselleşiyor,görünürleşiyor, estetize oluyor, pazara giriyor ve yeni topluluk tipleriyaratıyor. Bu kitap, değişimin yeni bir boyut ve derinlik kazandığı yenikentlileşme sürecinde dini hayatın çeşitlenen tezahürlerini ve kentdindarlığını anlam merkezli bir yaklaşımla tartışmaya açmaktadır. Türkiye’de din ve modernlik ilişkisi,tarihsel, kültürel ve siyasal süreçlere egemen olmuş çok yönlü bir etkileşimeksenidir. Bu eksenin kültüre ve gündelik hayata yansıyan etkileri ise en somutbiçimde kentsel mekâna yansımakta, dinin toplumsal etkileri yeni kent kültürüve kimliği ile birlikte evrilmektedir. Küreselleşmenin benzeştirdiği yenikentlilik süreçleri yalnızca yapısal değişimleri değil, kent dindarlığıbağlamında dini anlayış ve yorumları da kuşatmaktadır. Dolayısıyla kent-sonrasıbir dünyada kent dindarlığını konuşmak daha anlamlı ve önemli hale gelmektedir.Kitap, KentDindarlığı olgusunu eksene alarak dini hayata ilişkin saha gözlemlerini anlammerkezli bir çözümlemenin konusu yapmakta ve bu süreci anlamak isteyen herkesiyeniden düşünmeye çağırmaktadır.&nbsp;</p

    Postoperative Adenosine Deaminase Activity Predicts Complications After On-Pump Cardiac Surgery

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    Background: Various factors associated with cardiopulmonary bypass (CPB) can produce an inflammatory response, resulting in morbidity and mortality. The aim of this study was to investigate how adenosine deaminase (ADA) activity changes after surgery in relation to the emergence of CPB-related complications. Methods: The study included 78 patients, of whom 30 had complications. Blood samples were collected three times: on admission to the ward (preoperative), on the first postoperative day, and on the fifth postoperative day. The blood samples were analyzed for routine hematological and biochemical variables. In addition, serum ADA activity was evaluated, and normalized ADA [ADA(Nor)] levels were calculated. Results: On postoperative day 1, ADA and ADA(Nor) levels differed between the groups. In multivariate analysis, left atrium diameter (p = 0.015), and ADA(Nor) (p = 0.001) on postoperative day 1 were significant predictors of CPBrelated complications. Receiver operating characteristic curve analysis showed that the area under curve for postoperative first day ADA(Nor) was 0.767 (95% confidence interval 0.664-0.871). Using a cut-off value of 11.87, postoperative first day ADA(Nor) predicted postoperative complication emergencies with 63.3% sensitivity and 77.1% specificity. Conclusion: This study is the first to identify blood ADA(Nor) activity as an independent risk factor for the development of postoperative CPB-related complications

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