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The Relationship of cointegration between some macroeconomic factors and shares prices: an empiric research with the ardl bound testing approach
Get PDFIntroduction: The issue of factors affecting stock prices has always been an important and current issue, both for institutions and individual investors.
Aim: The aim of this study is to analyze whether there is a cointegration relationship between macroeconomic factors and stock prices in Turkey with the ARDL Bounds Test.
Method: Monthly BIST100 index prices and macroeconomic factors such as interest, gold and exchange rates between 2008 and 2020 are included in the analysis. First, the stationarity of the series was examined and then it was tried to be determined by using the ARDL bounds testing whether there is a cointegration relationship between stocks and macroeconomic factors.
Findings: Analysis results showed that there is a cointegration relationship between stock prices and macroeconomic factors
An in vitro investigation of genotoxic effects of dexketoprofen trometamol on healthy human lymphocytes
No full textNon-steroidal anti-inflammatory drugs are drugs with analgesic, antipyretic, and anti-inflammatory effects. This study uses in vitro methods to investigate the potential and unknown genotoxic effects of dexketoprofen trometamol, an active substance in painkillers, on healthy human lymphocytes. In this study, a cytokinesis-block micronucleus cytome assay is used to investigate potential clastogenic, aneugenic activity and to identify chromosome breakages caused by the active drug substance dexketoprofen trometamol; a comet assay is performed to identify the genotoxic damage resulting from DNA single-strand breaks; a real-time reverse transcription polymerase chain reaction panel system is used to evaluate the potential negative effects on the expression of the genes responsible for DNA damage assessment. Dexketoprofen trometamol induces toxic effects in healthy human lymphocytes at concentrations of 750–1000 µg/mL and above, and shows clastogenic, aneugenic activity by inducing micronucleus formations at exposures of 750–500 µg/mL. At concentration intervals of 1000, 500, 250, 100 µg/mL, dexketoprofen trometamol also resulted in DNA damage in the form of strand breaks, as demonstrated by highly significant increases in DNA tail length and density comet parameters when compared to spontaneous values. Human lymphocytes exposed to 750–100 µg/mL dexketoprofen trometamol were found to have significantly increased levels of expression of the XPC, XRCC6, PNKP genes in the DNA damage signaling pathway. It can be concluded that dexketoprofen trometamol may have cytotoxic, cytostatic, genotoxic effects on healthy human lymphocytes in vitro, depending on the concentration and duration of exposure. It is anticipated that this outcome will be supported by advanced studies
Incorporation of propionibacterium shermanii subsp. freudenreichii in probiotic dairy drink production: physicochemical, rheological, microbiological and sensorial properties
Get PDFThe aim of this study was to investigate the use of Propionibacterium shermanii subsp. freudenreichii as a combined culture with Lactobacillus acidophilus (AP), Bifidobacterium animalis subsp. lactis (BP), Lactobacillus casei (CP) and Lactobacillus rhamnosus (RP) in probiotic dairy drink production. Although Propionibacterium spp. is used for many purposes including biopreservative and adjunct culture, in this study, probiotic dairy drinks containing P. freudenreichii were evaluated in terms of their physicochemical, rheological, microbiological and sensory properties. The results of the study showed that P. freudenreichii can also be suitable for the production of probiotic drinks and that there are no adverse effects on the product characteristics
Mardin’in UNESCO dünya mirası listesi adaylık süreci
Get PDFGeyik, Nazl� Ece (�zmir Kavram Meslek Y�ksekokulu)Güneydoğu Anadolu’nun tarihi ve kültürel dokusuyla en önemli kentlerinden biri olan Mardin, kesin olarak bilinmemekle birlikte MÖ 4500’lerden itibaren Subari, Sümer, Akad, Babil, Asur, Pers, Bizans, Selçuklu, Artuklu, Osmanlı gibi pek çok uygarlığa ev sahipliği yapmış, açık hava müzesi niteliğinde bir kenttir. Mardin tarihi kent merkezi, arkeolojik ve tarihi değerleri, sivil, askeri, dini yapıları, özgün konut dokusunun yanı sıra; çeşitli ve farklı din, kültür, inanış ve etnik kökenlerin oluşturduğu somut olmayan kültürel mirasıyla da ender rastlanan bir kültürel peyzaj değeridir
COVID-19 sürecinin öğrettikleri: Temiz şehir
Get PDFBir hastalığın sınırları aşması ve tüm dünyanın sorunu haline gelmesine pandemi denir. Pandemiler olağan olaylar değildir. Sıklıkları, süreleri belirsiz ve değişkendir. Bilim adamları tarafından geleceğe yönelik yapılan çıkarımlar (projeksiyonlar) sayesinde, önceden tahmin söz konusu olabilir, ancak yanılma payı yüksektir
Epistemology according to the Kalam of Ahl al Sunnah
Get PDFThe method or procedure used in each field differs from the others in accordance with its internal structure. If I am not mistaken, the basic method of social sciences and humanities consists of thinking on and generating concepts. In order not to make mistakes by generalizing, I will try to approach the subject from the perspective of my field called "kalam" among the experts and known as belief and faith colloquially.
In our field, the principles to be used in accessing knowledge are called method. In general, it is possible
to talk about three methods in the field of thought or faith. Two of these methods have been used since
ancient times. The third has been used from time to time or there have been few communities that use it.
The first of these is the dogmatic or transfer method, which is as old as human history. According to this
method, God or special persons authorized by God know everything best. These things are beyond
others' intellect. Since they are not special enough to communicate with God, they must be subject to
special ones. Besides, this is God's command. Disobedience means rebelling against God. As is well
known, those who oppose God are punished by special persons chosen by God with the punishment they
-Shahrastani, ts. 2/48)
Intergenerational knowledge transfer in family Firms: A Research in Afyonkarahisar province
No full textIntroduction: Transferring knowledge to the next generation is a very important process for longevity and sustainability with challenging during the family firms' succession. Researches on knowledge transfer in literature considering that family firms tend to maintain knowledge within the family to continue their operations by limiting transfer between the members. Although it cannot be said that this transfer was successfully carried out by all family firms with this tendency. Accordingly, the motivation for this study is to explore how knowledge is transferred between generations in the family firms.
Aim: Based on the motivation of the study, the aim of this paper to investigate intergenerational knowledge transfer on Turkish delight and confectionery manufacturers in Afyonkarahisar province that were known as a more traditional family firm structure.
Method: A semi-structured interview method was used in the study. The firms determined from the profession list of the Afyonkarahisar Chamber of Commerce and Industry were reached and a meeting was requested. Interviews were made with 12 managers who were family members from different generations who agreed to participate in the study.
Findings: It has been observed that the family firms in the research have a well-established structure. In these firms, there is no systematic knowledge transfer process between generations as stated in the literature. Their knowledge and competencies are shaped based on the founder and transferred to other generations through informal channels determined by the founder
Content analysis of studies on sexual abuse in childhood
No full textAmaç: Çocuk cinsel istismarı çocuğun fiziksel, zihinsel ve duygusal gelişim düzeyi göz önüne alındığında anlamlandıramayacağı, kendi rızası dışında gelişen cinsel eylemlere zorla ya da ikna edilerek dâhil edilmesidir. Çocukluk döneminde cinsel istismara maruz kalmak çocuğun tüm gelişim alanlarını uzun ve kısa vadeli olarak önemli ölçüde etkileyen küresel halk sağlığı sorunlarından biridir. Bu çalışmanın amacı çocukluk döneminde görülen cinsel istismara yönelik yapılmış çalışmaların sistematik bir şekilde değerlendirilmesidir.
Yöntem: Değerlendirmede 01.01.2019 - 05.05.2020 tarihleri arasında PubMed veri tabanına ait yayınlardan ‘child sexual abuse’ sözcük grubu kullanılarak yapılan arama ile ulaşılan çalışmalar taranmıştır. Bu anahtar kelime ile ilgili tarih aralığı sınırlandırılarak toplam 3201 çalışma görüntülenmiş olup tam metin olarak 2649 çalışmaya ulaşılmıştır. Konunun içeriği, yaş aralığı (0-18), başlık ve anahtar kelime uygunluğu, araştırma makalesi olması gibi kriterler değerlendirilerek uygun olmayan araştırmalar, derleme makaleler ve meta-analiz çalışmaları bu çalışmaya dâhil edilmemiştir. Değerlendirme kriterlerini karşılamayan çalışmalar çıkarıldığında toplam 12 makale incelenmiştir.
Bulgular: Çalışmalar incelendiğinde çalışma grubunun çoğunu ergenlerin oluşturduğu, cinsel istismar öyküsü olan çocukların, istismarcılarının çoğunun yakınlarındaki kişiler olduğu, istismarın zararlı madde kullanımı, depresyon, anksiyete, uyku bozuklukları, travma sonrası stres bozukluğu ile ilgili doğrudan ilişkisi olduğu ve intihar etme düşüncelerinin olduğu bulunmuştur.
Sonuç: Çocuk cinsel istismarı çocuğun hayatında derin izler bırakarak yetişkinliğe kadar etkisini sürdüren problemlere neden olmaktadır. Cinsel istismarın risk faktörleri ve sonuçları arasındaki ilişkiyi incelemeye yönelik araştırmalar, erken müdahale ve önleme programlarına yönelik araştırmalara göre daha fazladır. Çocuk cinsel istismarı yaygınlığını azaltmak için gelişimi bilen kişiler tarafından yapılacak değerlendirmelere, aile ve okul temelli programlara, bu değerlendirme ve programların etkililiğinin araştırılmasına ihtiyaç vardır.Aim: Child sexual abuse is the forced or persuaded involvement of the child in sexual actions which the child cannot make sense considering the level of physical, mental and emotional development of child without his/her consent. Exposure to sexual abuse in childhood is one of the global public health problems that significantly affect all areas of development of the child in the long and short term. The aim of this study is to evaluate the studies on sexual abuse seen in childhood in a systematic way.
Method: In the evaluation, the studies conducted using the word group “child sexual abuse” belong to PubMed database published in English between 01.01.2019 - 05.05.2020. With this keyword, a total of 3201 studies were displayed and 2649 studies were reached as full text limited to this. The criteria such as content of subject, age range (0-18), title and keyword suitability, being research articles are evaluated but inappropriate studies, review articles and meta-analysis studies are not included in this study. Total of 12 articles were examined when studies that didn’t obviate the evaluation criteria were removed.
Results: When the studies were examined, there were found that the majority of the study group consisted of teenagers, most of children have a history of sexual abuse are close to abusers, abuse has a direct relationship with harmful substance use, depression, anxiety, sleep disorders, posttraumatic stress disorder and they have suicidal thoughts.
Conclusion: Child sexual abuse engrave in child’s life and causes problems that continue effectively till adulthood. Research to examine the relationship between the risk factors and consequences of sexual abuse is higher than research for early intervention and prevention programs. In order to decrease the prevalence of child sexual abuse, there are needs for evaluations to be made by people who know the development, family and school-based programs, and researching the effectiveness of these evaluations and programs
Analysis of some physicochemical, rheological, sensorial properties, and probiotic viability of fermented milks containing enterococcus faecium and enterococcus durans strains
No full textThe aim of this research was to observe the combined usability of Enterococcus faecium and Enterococcus durans strains, which are resistant to adverse environmental conditions, together with commercial probiotic starters in the production of probiotic fermented milk. Accordingly, eight different probiotic fermented milks were produced; AF:Lactobacillus acidophilus + Enterococcus faecium, BF:Bifidobacterium animalis subsp. lactis + Enterococcus faecium, CF:Lactobacillus casei + Enterococcus faecium, RF:Lactobacillus rhamnosus + Enterococcus faecium, AD:Lactobacillus acidophilus + Enterococcus durans, BD:Bifidobacterium animalis subsp. lactis + Enterococcus durans, CD:Lactobacillus casei + Enterococcus durans, RD:Lactobacillus rhamnosus + Enterococcus durans. As a result of the data obtained in the study, it was found that fermented dairy products containing Enterococcus faecium and Enterococcus durans had no negative effects on the physicochemical, rheological properties and probiotic viability, and positively affected the sensory properties of the samples. The viscosity and hardness values of probiotic fermented milk produced by combining with E. durans were higher than by combining with E. faecium and serum separation was not occurred. Also, probiotic bacteria viability was higher than 7 log cfu/ml level at the end of the storage period.Ege University Scientific Research Fund Council. Grant Number: Project No: 14‐ZRF‐01
Iconoclasm period in Byzantine history and the effect of iconoclasm on Hagia Sophia
Get PDFGeyik, Nazl� Ece (�zmir Kavram Meslek Y�ksekokulu)(726-843) seneleri arasındaiki farklı şekilde ortaya çıkan İkonoklazma Dönemi, Bizans’ın ve Bizans imparatorlarının “yönetim ile kilise” ilişkisi bağlamında yaşadığı toplumsal, siyasal, ekonomik ve dış güçlerden kaynaklanan sorunları da kendi içerisinde barındırdığı kargaşa dönemidir. Bizans ile Batı kilisesinin birbirinden ayrılmasıyla ikon sanatı ve kültürü, Ortodoks dünyasında önem arz etmeye başlamıştır. Bunun sonucunda yaşanan İkonoklazma Dönemi, Bizans kiliseleri için bir dönüm noktası olmuştur. Dünya mimarlık tarihinin günümüze kadar ayakta kalmış en önemli anıtları arasında yer alan Ayasofya; mimarisi, ihtişamı, büyüklüğü ve işlevselliği yönünden sanat dünyası açısından önemli bir yer teşkil etmekte, dini ve simgesel olarak bulunduğu şehre değer katmaktadır. Kilise olarak inşa edilen, ardından camiye çevrilen ve sonradan müze olarak düzenlenen yapı; simgesel önemini günümüzde de korumaya devam etmektedir. 726’da tüm ikon ve heykellerin Ayasofya’dan kaldırılması sonrasında, günümüze kadar gelebilen insan sureti tasvirlerini içeren mozaiklerin tümü, İkonoklazma Dönemi sonrasına aittir. Bununla birlikte insan sureti tasviri içermeyen mozaiklerden bazılarının da 6. yüzyılda yapılan ilk mozaikler olduğu anlaşılmaktadır. Bu çalışmada, İkon ve ikonoklazma kavramlarının tanımıylaberaber İkonoklazma Dönemi’nden bahsedilerek; bu dönemde bazı mozaiklerin değiştirilmesi ve ikonoklazma sürecinin bitmesiyle yapılan kimi mozaiklerin ve mimari yapıların kültürel hafızadaki değişimini, Ayasofya örneği özelinde araştırılması hedeflenmiştir.The Iconoclasm Period, which emerged in two different ways between the years (726-843), is the period of turmoil in which the Byzantine and Byzantine emperors also had problems arising from the social, political, economic and external powers that they experienced in the context of the "administration and church" relationship. With the separation of Byzantine and Western churches, icon art and culture started to be important in the Orthodox world. As a result, the Iconoclasm Period was a turning point for Byzantine churches.Hagia Sophia, which is one of the most important monuments of the history of world architecture that has survived tothe present day; In terms of its architecture, magnificence, size and functionality, it constitutes an important place for the art world and adds value to the city where it is religious and symbolic. The building, which was built as a church, then converted into a mosque and later organized as a museum; it continues to maintain its symbolic importance today. After the removal of all the icons and sculptures from Hagia Sophia in 726, all the mosaics containing the depictions of the human image that can survive are from the post-Iconoclasm Period. However, it is understood that some of the mosaics that do not contain a human image are the first mosaics made in the 6th century.In this period, it was aimed to investigate the change of some mosaics and architectural structures made in the cultural memory by changing some of the mosaics and the iconoclasm process in the example of Hagia Sophia