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Influence of intermittent fasting during Ramadan on Circadian variation of symptom-onset and prehospital time delay in acute ST-Segment elevation myocardial infarction
Ramadan interferes with circadian rhythms mainly by disturbing the routine patterns of feeding and smoking. The objective of this study was to investigate the circadian pattern of ST elevation acute myocardial infarction (STEMI) during the month of Ramadan. We studied consecutive STEMI patients 1 month before and after Ramadan (non-Ramadan group-NRG) and during Ramadan (Ramadan group-RG). The RG group was also divided into two groups, based on whether they chose to fast: fasting (FG) and non-fasting group (NFG). The time of STEMI onset was compared. A total of 742 consecutive STEMI patients were classified into 4 groups by 6 h intervals according to time-of-day at symptom onset. No consistent circadian variation in the onset of STEMI was observed both between the RG (P =.938) and NRG (P =.766) or between the FG (P =.232) and NFG (P =.523). When analyzed for subgroups of the study sample, neither smoking nor diabetes showed circadian rhythm. There was a trend towards a delay from symptom onset to hospital presentation, particularly at evening hours in the RG compared with the control group. In conclusion, there was no significant difference in STEMI onset time, but the time from symptom onset to hospital admission was significantly delayed during Ramadan
CMC-based edible coating composite films from Brewer's spent grain waste: a novel approach for the fresh strawberry package
This study points to the coated strawberry with new edible films originating from the components of Brewer's spent grain (BSG) obtained as a large amount of waste during brewing. The aim of this study was to measure the high protein, phenolic compounds and cellulose from the BSG waste, which is created as waste in the brewing and mostly used as animal feed, with a new approach to coating strawberries. Cellulose, protein and phenolic compounds were extracted from BSG which is high in these components. Carboxyl methylcellulose (CMC) was synthesized from the obtained cellulose to produce edible films incorporated with different concentrations of protein and phenolic compounds of BSG. The production of the films was characterized by Fourier transform infrared spectroscopy (FT-IR), thermogravimetric analysis (TGA), scanning electron micrographs (SEM) and mechanical analysis and their antioxidant activities. Weight loss, titration acidity, pH, soluble solids and anthocyanin content were determined for uncoated and coated strawberries with each formulation. Total phenolic was observed to be 2.28 mg GAE/g, and the total protein amount in BSG was observed to be 26.81 g per 100 g dry weight. The results showed that the protein and phenolic compounds used in CMC benefited the CMC film-coated strawberry and could be used as a food packaging material in future. The appearance of composite film-coated strawberry was better than that of uncoated films at the end of the 5 days of storage at room temperature due to the protective properties of the film. Graphical abstract: [Figure not available: see fulltext.
The role of frailty score in early surgical treatment of elderly cholecystitis patients
The average life expectancy is increasing all over the world, and as a result, the number of elderly patients is increasing. Acute cholecystitis is one of the most common diseases requiring emergency surgical treatment in the elderly. In the literature, it has been reported that in the treatment of elderly patients with acute cholecystitis, physicians do not fully comply with the current literature recommendations due to some concerns and do not apply surgical treatment in the early period. The concept of frailty, which has come to the fore in geriatric assessment today, provides objective information about the general health status of the patient. In our study, the role of frailty assessment in the decision made regarding the early surgery in elderly patients with acute cholecystitis treated in our hospital was investigated. Methods: In our study, the clinical features, comorbidities, American Society of Anesthesiologists (ASA) scores, Canadian Study of Health and Aging (CSHA) frailty scale, treatment modalities and prognosis of patients over the age of 65 who were treated with the diagnosis of acute cholecystitis between January 2018 and January 2021 were evaluated retrospectively. Results: Of the 182 patients included in the study, 24 (13.2%) were found to be frail. It was observed that the mean age and multi-morbidity were higher in the frail group (p 0.05). Conclusions: In the treatment of the elderly cholecystitis patients, early surgical treatment is the most favorable treatment method in order to reduce re-admission and prevent possible complications. However, we think that a detailed geriatric evaluation should be made in a multidisciplinary manner for the decision making regarding the of surgical treatment of elderly patients, and frailty evaluation should also be made in this context
Sc2CX (X=N2, ON, O2) MXenes as a promising anode material: A first-principles study
MXenes' tunable properties make them excellent candidates for many applications in future nanoelectronics. In this work, we explore the suitability of Sc2CX (X=N2, ON, O2) MXenes to act as the active anode materials in Na-ion based batteries (NIBs) by means of ab initio simulations. After analyzing the structural and elastic properties of all the possible models to evaluate the energetically favorable N and O functionalization sites, our calculations show that both Sc2CON and Sc2CN2 present a clear metallic character, making them potential candidates as anode materials. The investigation of the most relevant features for anode performance, such as the adsorption and diffusion of Na atoms, the intrinsic capacity, the open circuit voltage, and the storage capacity, shows that both systems are serious alternatives to the most common 2D materials currently employed in alkali metal batteries. In particular, Sc2CN2 presents better diffusion behavior thanks to the absence of Na clustering on its surface, with optimal diffusion barriers comparable to other 2D materials, such as MoN2, while the values of diffusion barriers for Sc2CON are at least three times smaller than those found for other anode candidates. Similarly, while the capacity of Sc2CON is close to the one reported for 2D Sc2C, Sc2CN2 possesses a power density more than twice higher than the ones of 2D materials, such as Sc2C, graphite, and MoS2. Our results, thus, confirm the urge for further experimental exploration of the MXene Sc2CX (X=N2, ON, O2) family as anode material in NIBs
Comparison of different machine learning models for mass appraisal of real estate
The present study aimed to compare five machine learning techniques, namely, artificial neural network (ANN), support vector machine (SVM), chi-square automatic interaction detection (CHAID), classification and regression tree (CART), and random forest (RF) for mass appraisal of real estate. Firstly, 1982 precedent data was collected throughout the entire study area for train and test models. Secondly, a total of 68 variables were considered for the mass appraisal. Subsequently, the five machine learning techniques were applied. Finally, the receiver operating characteristic (ROC) and various statistical methods were applied to compare five machine learning techniques
Un estudio morfométrico de Cráneos de Razas de Ovejas Hasmer y Hasak
The aim of the study was to investigate the head structures of two domestic sheep breeds (Hasak and Hasmer) in Turkey. Gender neutral eight adult Hasmer sheep of 45-66 kg and eight Hasak sheep breeds of 43-66 kg obtained from Bahri Dag.das, International Agricultural Research Institute were used in this study. Measurements were made using digital caliper from 40 points on the skulls of both species. The skull of Hasmer sheep (265.56 +/- 14.08) was longer than the skull of Hasak sheep (262.86 +/- 9.65). However, the length of the arcus alveolaris maxillaris (77.01 +/- 5.08), the length of the molar teeth (50.81 +/- 1.22) and the length of the premolar teeth (26.16 +/- 4.62) of Hasak sheep were compared to the Hasmer sheep (71.59, +/- 5.25; 47.99 +/- 3.64; 24.03 +/- 3.76, respectively) was observed to be greater. According to these findings, although the skull length of Hasak sheep was shorter than that of Hasmer sheep and arcus alveolaris maxillaris in which molar and premolar teeth were placed was longer. In Hasmer sheep the values of greatest breadth of the foramen magnum, height of the foramen magnum (basion - opisthion), greatest neurocranium breadth-greatest breadth of the braincase (euryon - euryon) were higher than those of Hasak sheep. The difference between these values was also statistically significant (p <0.05). The lateral length of the premaxilla (nasointermaxillare- prosthion) parameter measured between these two species was statistically very important (p <0.01). In conclusion, in this study craniometric values depending on skull morphology of Hasmer and Hasak sheep which accepted as native breeds of Turkey were tried, to reveal similarities and differences with other sheep breeds in both amongst themselves.El objetivo del estudio fue investigar las estructuras de la cabeza de dos razas de ovejas domésticas (Hasak y Hasmer) de Turquía. En este estudio se utilizaron ocho ovejas Hasmer adultas de género neutral de 45-66 kg y ocho ovejas de raza Hasak de 43-66 kg, obtenidas del Instituto Internacional de Investigación Agrícola Bahri Dagdas. Las mediciones en los cráneos de ambas especies se realiza-ron con caliper digital de 40 puntos. El cráneo de la oveja Hasmer (265,56 ± 14,08 mm) era más largo que el cráneo que el de la oveja Hasak (262,86 ± 9,65 mm). En las ovejas Hasak la longitud del arcus alveolaris maxillaris fue 77,01 ± 5,08 mm, la longitud de los dientes molares fue 50,81 ± 1,22 mm y la longitud de los dientes premolares fue de 26,16 ± 4,62 mm, en cambio en las ovejas Hasmer fue de 71,59 ± 5,25 mm; 47,99 ± 3,64 mm; 24,03 ± 3,76 mm, respectivamente. Según estos hallazgos, la longitud del cráneo de la oveja Hasak era más corta que la de la oveja Hasmer y el arcus alveolaris maxillaris en el que se colocaron los dientes molares y premolares era más largo. En ovinos Hasmer los valores de mayor amplitud del foramen magnum, altura del foramen magnum (basion - opisthion), mayor amplitud del neurocráneo-mayor amplitud de la caja craneana (euryon - euryon) fueron superiores a los de las ovejas Hasak. La diferencia entre estos valores también fue estadísticamente significativa (p <0,05). El parámetro de longitud lateral del premaxilar (nasointermaxillare-prosthion) medido entre estas dos especies fu estadísticamente significativo (p <0.01). En conclusión, los valores craneométricos en relación a la morfología del cráneo de las ovejas Hasmer y Hasak que se definieron como razas autóctonas de Turquía revelaron similitudes y diferencias con otras razas de ovejas
Experimentally flight performances comparison of octocopter, decacopter and dodecacopter using universal UAV
This study presents a comparative analysis of different unmanned aerial vehicle (UAV) configurations using a proposed universal UAV. The octocopter, decacopter, and dodecacopter were experimentally evaluated through point tracking flight performances and vibration level analyses. To the best of our knowledge, this is the first study to conduct a comparative analysis of these configurations on the same platform. Our findings indicate that the dodecacopter exhibited the best overall performance, whereas the decacopter showed the lowest roll angle error. Notably, the implemented decacopter exhibited the highest pitch angle error and north position error due to its asymmetric rotor placement in the pitch axis. We observed that the octocopter demonstrated the best vibrationless flight performance, while increasing vibration magnitude was observed with an increase in the number of rotors
Influence of Ti and Nb addition on the microstructure, mechanical, and machinability properties of 316L stainless steel fabricated by powder metallurgy
In this study, titanium and niobium element powders in determined amounts (0.25 and 0.5wt%) were added into the 316L stainless steel matrix by means of powder metallurgy (PM) technology, either singly or in pairs, and the desired composition was obtained as a powder mixture. The powders used in the study were cold pressed tensile sample molds prepared in ASTM 8M standards, unidirectionally cold pressed under 700MPa compression pressure and formed into blocks. After pressing, the raw strength samples were sintered in an atmosphere-controlled tube furnace at 1325°C for 2h in an argon atmosphere. The microstructure and mechanical properties of the produced PM steels were characterized by optical microscope, SEM, EDS, and tensile test. The results showed that the stainless-steel samples with 0.25(Ti-Nb) added composition to 316L stainless steel had the highest yield strength and tensile strengths. However, with the addition of 0.5Ti, 0.5Nb, and 0.5(Ti-Nb) to 316L stainless steel, a decrease was observed in the mechanical properties. Moreover, the MQL machining is better on the machining output such as surface roughness and cutting temperature than dry machining in terms of a sustainable machining process
Usability of Carbon Sources as Sucrose, Honey and Agave Syrup in Fermentation of Lemonade with Water Kefir Grains
The aim of this study was to develop an innovative and functional beverage formulation with probiotic properties using carbon sources such as sucrose, agave syrup, and honey. Analysis showed that lemonade-honey had the highest antioxidant values on day 0, but activity decreased on day 14. The numbers of Lactococcus ssp., Lactobacillus ssp., and total bacteria in lemonade-honey were found to be higher on the days 0 and 7 of fermentation than on day 14. The highest glucose and fructose concentrations and the lowest sucrose concentrations in lemonade-agave syrup and lemonade-honey were on day 7. At the end of fermentation, the highest concentration of vitamin C was detected in the lemonade-agave syrup formulation. All mineral substances analyzed in lemonade-honey reached their highest values on the days 7 and 14 of storage, especially phosphorus, potassium, iron, and zinc. In terms of sensory characteristics, the panelists gave higher scores for lemonade-agave syrup. As a result, all lemonade formulations proved to be suitable for water kefir. However, lemonade-agave syrup and lemonade-honey are recommended to be consumed within the first seven days due to their pleasant aroma, probiotic functional properties, better preservation of bioactive components, and lower acidity
Azerbaijan during the Great Seljuk Period
Orta Çağ ana kaynaklarında, özellikle Selçuklu Devleti dönemini araştırdığımızda, Azerbaycan bölgesinin Türkmenler için ne kadar önemli olduğunu görmekteyiz. XI. yüzyılın başlarından itibaren Oğuzların (Türkmenlerin) nüfusunun artması ile sadece İran coğrafyası değil Anadolu toprakları da bu iskân edilecek bölgelerden biri haline gelmişti. Bu yüzden bu bölgelere kalabalık göç dalgalarını zaman içerisinde görebiliyoruz. Aslında Anadolu topraklarına iskân edebilmek ve şayet o dönemin düşüncesinde Bizanslarla mücadele edebilmek için, Azerbaycan bölgesini bir askeri üst bölgesi haline getirebilmenin ne kadar önemli olduğu, daha sonraki süreçlerde etkilerini gösterecekti. Azerbaycan bölgesinin coğrafi ve siyasi bakımından özelliklerini göz önünde bulundurduğumuzda Selçuklu Devleti hükümdarları için bu bölgenin ne kadar önemli olduğunu görebiliyoruz. Bu araştırmada dönemin ana kaynaklarını da inceleyerek Selçuklu hükümdarlarının hem göç politikasında Türkmenleri yerleştirebilmek için, hem de Anadolu topraklarına geçebilmek için Azerbaycan bölgesini nasıl değerlendirdiklerini inceleyeceğiz.When we research the main sources of the Middle Ages, especially the period of the Seljuk State, we see how important the Azerbaijan region was for the people of Turkmen origin. With the increase in the population of Oghuzs (Turkmen) from the beginning of the 11th century, not only the geography of Iran but also the Anatolian lands became one of these regions to be settled. That's why we can see crowded migration waves to these regions over time. In fact, how important it was to make the Azerbaijan region a military upper zone in order to be able to settle in Anatolian lands and to fight against the Byzantines in the thought of that period would show its effects in the later processes. When we consider the geographical and political characteristics of the Azerbaijan region, we can see how important this region was for the rulers of the Seljuk State. In this research, we will examine the main sources of the period and examine how the Seljuk rulers evaluated the Azerbaijan region both in order to settle the Turkmen in their immigration policy and to pass to the Anatolian lands