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    Rehabilitation of soils containing high salt levels with beneficial fungi

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    Soil salinity not only reduces the quality of the soil, but also causes ionic imbalance in the plant, competition in the nutrient uptake and toxic effects at high concentration. Combating salinity, which has become a greater stress factor due to impact of drought and high temperatures, is of great importance. In this study, 3 kg soil in pots, adjusted to 12 mS/m EC, under four different treatments (3 different fungi species and control) were compared in a laboratory environment. The experiment was designed with three replications for each subject and one plant in each pot. Fungi species (Clononotachys rosea, Trichoderma sp., Taloromyces funiculosus) were used as soil inoculant to reduce soil salinity. The soil electrical conductivity (EC) was between 9.25 and 9.95 mS/m within 1 month in tomato cultivated soils, while the EC of the plant-free medium was between 10.4 and 11.4 mS/m: thus, the salt content did not differ statistically. EC values of the saline soils was decreased by 21-, 17-, 29 %, respectively, when Trichoderma sp., Taloromyces funiculosus, Clononotachys rosea were applied to tomato plant growing soils. These fungi also decreased the soil EC values by 15-, 16-, 25 %, respectively, in the plant-free environment. The chlorophyll SPAD value of tomato plants grown in saline soils decreased from 22.65 to 0, however, the SPAD values of tomato plants grown in soils with Clononotachys rosea, Trichoderma sp., Taloromyces funiculosus were increased from 22.4-, 25.6-, 24.1 to 29.3-, 50.2-, and 24.5. Similar findings were also observed for the increase in the chlorophyll content of the tomato plant. The fungi mentioned above also contributed to the increase of soil macro (Ca, Mg, K, P) and micro (Fe, Cu, Zn, Mn) element contents, and to the improvement of soil available phosphorus amount (P2O5) with the increase in soil phosphorus content. Fungi inocula induced a statistically significant increase of soil micronutrient concentrations (p>0.05). Sodium (Na) concentration in saline soils did not change in inoculated-non-inoculated soils. These findings were interpreted as fungi inocula were not able to assimilate the salt from the soil, but they instead contributed to the release of macro and micro elements that were unavailable under saline conditions, possibly due to their metabolic activities. According to the results of soil analysis at the end of the experiment, it was revealed that the pH value was 7.72 in the control pots and 3.28 in the pots treated with Taloromyces funiculosus, and the EC value was 12.34 and 9.74 mS/m, respectively. Among the fungi studied, Taloromyces funiculosus was found to be more effective than other two fungi on decreasing soil salinity and increasing micronutrient availability to plants

    Evaluation of patients diagnosed with congenital hypothyroidism by newborn screening between 2011-2019 in Diyarbakir, Turkey

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    This study aimed to determine the incidence of congenital hypothyroidism in Turkey’s Diyarbakir Province and assess the development and growth conditions of people with congenital hypothyroidism. Patients born between 2011-2019 and diagnosed with congenital hypothyroidism within the scope of the newborn screening program were included. The medical records of these patients were retrospectively reviewed. The length and weight for age, weight for length, and body mass index standard deviation scores were calculated. We investigated the treatment status of the patients, whether their relatives had a similar disorder, and the presence of consanguinity between parents. Blood samples were collected from 380,592 newborns. As a result of further tests, 498 newborns were diagnosed with congenital hypothyroidism (incidence: 1/764). Demographic and anthropometric data of 241 patients were analyzed. The patients comprised 46.9% (n = 113) females and 53.1% (n = 128) males. It was determined that 44.4% of the individuals had transient congenital hypothyroidism and 53.6% had permanent congenital hypothyroidism. The parents of 29.8% of the individuals diagnosed with transient congenital hypothyroidism and 44.2% of the individuals diagnosed with permanent congenital hypothyroidism were consanguineous (P = .02). According to the latest anthropometric assessment, 6.8% of individuals diagnosed with congenital hypothyroidism had a weight z-score below −2 SD and 16.9% had a length z-score below −2 SD. The incidence of congenital hypothyroidism was higher in our region. The ratio of consanguinity between parents was higher in patients diagnosed with permanent congenital hypothyroidism than in those diagnosed with transient congenital hypothyroidism. According to the most recent follow-up, weight and age were found to be similar in patients with transient and permanent congenital hypothyroidism

    A Stylistic Analysis of “A Painful Case”

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    The style of an author is provided by effective matching between his/her thoughts and selection of linguistic items. Stylistic analyses involve both the study of style and the study of how effects and meanings are produced by a literary text. Stylistics, therefore, relates linguistic facts (linguistic descriptions) to meaning (interpretation) to show evidence for an interpretation of a text. This study analyses James Joyce’s "A Painful Case" in the aspect of stylistic features. The short story is about a platonic affair between a married woman and an isolated man, the breaking off of the affair, and its aftermath. The analysis of the short story begins with a general interpretation. Its significant stylistic features are pointed out in terms of lexis, grammar, figures of speech, cohesion and context. The short story’s title foreshows the cause of the inner conflict of the main character and deals with the theme of isolation. The opening paragraph of the short story consists only of declarative sentences. Joyce uses simple past tense in order to confirm compatibility with the figural narrative situation he used. In terms of the syllable-length of words, the selected passage contains mostly two-syllable words. Lexical repetitions direct one’s attention to the negative feeling such as loneliness. The passage bases upon implicit connections of meaning which are strengthened by repeat of words from the same semantic field. The use of free indirect speech and a detailed description about the room reveals the main character’s state of soul. The domain is indoor surroundings, and the tenor is formal. The 3rd person narrator takes the reader beyond the usual aspects of life through epiphany. Mr Duffy feels remorse about Mrs Sinico’s death and realizes that his pursuit of control and order has caused only to his loneliness. Emotional paralysis of Mr Duffy compels him into a lifelong loneliness. This study shows how the formal stylistic features are used as the basis for inferring the short story’s meaning and effect

    Akut Kalp Yetmezliğinde Tedavi Yaklaşımı

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    GIRIŞ Akut Kalp Yetmezliği (AKY) hastanın acil tıb- bi yardım alması için yeterince şiddetli bir kli- nik duruma, plansız bir hastaneye yatışa veya acil servis başvurusuna yol açan kalp yetmezliği semptomlarının ve/veya belirtilerinin hızlı veya aşamalı olarak başlamasını ifade eder (1). AKY’li hastalarının tedavilerinin planlanması için acil değerlendirilmesi gerekir. AKY, 65 yaş üstü kişi- lerde hastaneye yatışların önde gelen nedenidir (2). Yüksek mortalite ve tekrarlayan hastaneye yatış oranları mevcuttur. Hastane içi ölüm oranı %4 ila %10 arasında değişmektedir (3). Tabur- culuk sonrası 1 yıllık ölüm oranı %25-30, ölüm veya tekrar yatış oranları %45’ten fazladır (4). AKY, yeni başlayan KY’nin ilk belirtisi olabilir veya daha sıklıkla kronik KY’nin akut dekom- pansasyonuna bağlı ortaya çıkabilir (5). Akut de- kompanse kronik KY’si olan hastalarla akut pul- moner ödemli hastalar karşılaştırıldığında, akut pulmoner ödemi olanlar daha yüksek hastane içi mortaliteye sahiptirler ancak taburculuk sonra- sı mortalite ve yeniden hastaneye yatış oranları daha düşüktür (6). AKY’nin en sık tetikleyici fak- törleri atriyal fibrilasyon, akut MI veya iskemi, ilaç alımının (diüretik) kesilmesi, artmış sodyum yükü,miyokard fonksiyon bozukluklarına sebep olan ilaçlar ve aşırı fiziki efordur (7). Önceden var olan kardiyak disfonksiyonu olan hastalarda spesifik dış faktörler (anemi, GİS kanama, enfeksiyon vb.) AKY’yi hızlandırabilir (8)

    Evaluation of Hematological Parameters After Transcatheter Aortic Valve Replacement

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    Although transcatheter aortic valve replacement (TAVR) is safe and effective, mortality and bleeding events post procedure are important. The present study investigated the changes in hematologic parameters to evaluate whether they predict mortality or major bleeding. We enrolled 248 consecutive patients (44.8% male; mean age 79.0 ± 6.4 years) undergoing TAVR. In addition to demographic and clinical examination, blood parameters were recorded before TAVR, at discharge, 1 month and 1 year. Hemoglobin levels before TAVR 12.1 ± 1.8 g/dL, 10.8 ± 1.7 g/dL at discharge, 11.7 ± 1.7 g/dL at first month, 11.8 ± 1.4 g/dL at first year (Hemoglobin values compared with pre-TAVR, P < .001, P = .019, P = .047, respectively). Mean platelet volume (MPV) before TAVR 8.72 ± 1.71 fL, 8.16 ± 1.46 fL at discharge, 8.09 ± 1.44 fL at first month, 7.94 ± 1.18 fL at first year (MPV values compared with pre-TAVR, P < .001, P < .001, P < .001, respectively). Other hematologic parameters were also evaluated. Hemoglobin, platelet count, MPV, and red cell distribution width before the procedure, at discharge, and at the first year did not predict mortality and major bleeding in receiver operating characteristic analysis. After multivariate Cox regression analysis, hematologic parameters were not independent predictors of in-hospital mortality, major bleeding, and death at 1 year after TAVR

    Local Pattern Transformation-Based convolutional neural network for sleep stage scoring

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    Sleep stage scoring is essential for the diagnosis and treatment of sleep disorders. However, manual sleep scoring is a tedious, time-consuming, and subjective task. Therefore, this paper proposes a novel framework based on local pattern transformation (LPT) methods and convolutional neural networks for automatic sleep stage scoring. Unlike in previous works in other fields, these methods were not employed for manual feature extraction, which requires expert knowledge and the pipeline behind it might bias results. The transformed signals were directly fed into a CNN model (called EpochNet) that can accept multiple successive epochs. The model learns features from multiple input epochs and considers inter-epoch context during classification. To evaluate and validate the effectiveness of the proposed approach, we conducted several experiments on the Sleep-EDF dataset. Four LPT methods, including One-dimensional Local Binary Pattern (1D-LBP), Local Neighbor Descriptive Pattern (LNDP), Local Gradient Pattern (LGP), and Local Neighbor Gradient Pattern (LNGP), and different polysomnography (PSG) signals were analyzed as sequence length (number of input epochs) increased from one to five. 1D-LBP and LNDP achieved similar performances, outperforming other LPT methods that are less sensitive to local variations. The best performance was achieved when an input sequence containing five epochs of PSG signals transformed by 1D-LBP was employed. The best accuracy, F1 score, and Kohen’s kappa coefficient were 0.848, 0.782, and 0.790, respectively. The results showed that our approach can achieve comparable performance to other state-ofthe-art methods while occupying fewer computing resources because of the compact size of EpochNet

    Cultural studies Çemka Höyük A Stage ground stone ornaments

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    Ilısu ve HES projesi kapsamında 2019 yılında Çemka Hüyük'te Mardin Müze Müdürlüğü başkanlığında ve Doç. Dr. Ergül Kodaş'ın bilimsel danışmanlığında yürütülen arkeolojik kazı çalışmasında bulunan sürtme taş süs eşyaların incelenmesi ve bunların kullanım işleviyle ilgili eldeki kaynaklara dayanarak yeni bilgilere ulaşılabilmesi amaçlanmaktadır. Yaklaşık olarak 11.700 yıllık bir tarihe sahip olan yerleşim yerinde açığa çıkartılan sürtme taş süs eşyaları ile ilgili yapılacak çalışmalarla yeni veriler tespit edilmiş ve bu verilerin Yukarı Dicle Vadisi'ndeki çağdaş yerleşim yerleriyle karşılaştırılması yapılarak, bölgedeki neolitikleşme sürecinde sürtme taş süs eşyalarının hem kronolojik gelişimi hem de kültürel bağlarının varlığının incelenmesi amaçlanmıştır.As part of the Ilısu and HEPP project, Mardin Museum Directorate and Assoc. It is aimed to examine the ground stone ornaments found in the archaeological excavation work carried out under the scientific consultancy of Ergül Kodaş and to reach new information based on the available sources about their usage function. With the studies to be carried out on the ground stone ornaments unearthed in the settlement, which has a history of approximately 11,700 years, new veri were determined and these data were compared with the contemporary settlements in the Upper Tigris Valley, and both the chronological development and cultural ties of the ground stone ornaments in the neolithicization process in the region were determined. to examine its existence

    Does oxidative status affect serum sclerostin levels in patients with type 2 diabetes mellitus?

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    Introduction: Sclerostin is a glycoprotein known as a negative regulator of bone formation, predominantly expressed by mature osteocytes. There is no causative evidence information on the role of sclerostin in the pathogenesis of type 2 diabetes mellitus (T2DM) in humans. Aim: This study aimed to investigate the relationship between serum sclerostin levels and oxidative status and biochemical parameters in T2DM patients and healthy people. Materials and methods: This cross-sectional study, conducted in a clinical trial center, included 45 subjects with T2DM and 45 subjects as controls. Results: Serum sclerostin, total oxidative status (TOS), albumin, and ferritin levels were significantly higher in T2DM patients than in the control group (p<0.05). Total antioxidant status (TAS) was significantly higher in the control group (p<0.05). There was a weak positive correlation between sclerostin and TOS (r=0.23, p=0.03) and a weak negative correlation between sclerostin and TAS (r=-0.28, p=0.03). Conclusions: We have demonstrated that serum sclerostin levels increase in patients with T2DM and that the increased sclerostin levels are associated with oxidative stress

    The saved area and art

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    Modernite, Aydınlanma aklı, Fransız ihtilali ve Sanayi Devriminden oluşan üç sacayağı üzerine inşa edilmiştir. Aydınlanma insana, bilim ve teknolojideki gelişmelerle güzel, konforlu yaşam vaat etmişti. Fakat kimilerine göre bu vaatler modern bireyi ve doğayı, egemenlik altına almakla sonuçlanmıştır. Paris'te özgürlük, eşitlik, adalet kavramları için başlatılan Fransız Devrimi, modernitenin siyasi uzamıdır. Devrim, Ulus devlete ve burjuvanın örgütlediği kapitalizme bayrak açmıştır. Sanayi Devrimiyle endüstrileşen toplum ise endüstrileşen kültürü ve bireyi doğurmuştur. Zamanla her şeye müşteri olan birey tükettikçe var olmuş, doğadan ve kendi doğasından uzaklaşmıştır. Akılcı, maddeci modern birey kendini sıkışmış, çaresiz, yalnız hissetmiştir. Mülkiyetin, iş bölümünün, zorunlu çalışmanın sonucu olarak birey, kendine ve doğaya yabancılaşmış, bir kaçışa sürüklenmiştir. Bu kaçış bir sığınak arayışıdır. Bu çalışmada kaçış içindeki bireye, Kurtarılmış Alan olarak oyun bağlamında sanat yapıtının, nasıl sığınak olabileceğini açıklamak amaçlanmıştır. Bu alandaki yaratım incelenmiş; tutkuyla, oyunla, kendiliğindenlikle, amaçsız, faydasız, kendine içkin, bir bebeğin anlamsız karalaması olarak ele alınmıştır. Tarama yöntemi kullanılan bu tezde mevcut kaynaklar taranmış, elde edilen bulgularla sanat yapıtları, sanatçılar ve düşünürler, tez konusu bağlamında yorumlanmıştır. Ayrıca tez yazarı tarafından oluşturulan sanatsal çalışmalar da konunun anlamlandırılması bağlamında teze dâhil edilmiştir. Sonuç olarak; kaçış içindeki modern insanı, gerçek hayattan koparacak, özgürleşebilecek, çocuğun büyülü coşkusunu barındıran bu kurtarılmış özerk alanın anahtarı oyundur; yani sanattır.Modernity was built on three pillars: the Enlightenment mind, the French Revolution and the Industrial Revolution. The Enlightenment promised people a beautiful, comfortable life through advances in science and technology. However, according to some, these promises resulted in the domination of the modern invidual and nature. The French Revolution, launced in Pris for concepts of freedom, equality and justice, is the political space of modernity. The revolution raised the flag fort he nation state and capitalism organized by the bourgeoisie. Industrial society with the Industrial Revolution gave birth to industrialized culture and the individual. Over time, the individual, who became a customer for everything, existed as he/she consumed and moved away from natüre and his/her own nature. The rational metarialistic modern individual felt trapped, hekpless and alone. As a result of property, division of labor and forced labor, the indiviadual become alienated from himself/herself and nature, and has been driven to escape. This escape is a search for refuge. This study aims to explain how the work of art can be a refuge fort he escaping individual in the context of play as a rescued space. The creation in this field was analyzed; it was handled with passion, play, spontaneity, purposeless, useless, intrinsic to itself, as the meaningless scribblingof a baby. In this thesis, in which the survey method was used, existing sources were scanned, and artworks, artists and thinkers were interpreted in the context of the thesis topic with findings obtained. In addition, the artistic Works created by the thesis author were also included in the thesis in the context of making sense of the subject. As a result, the key to this liberated autonomous space that will break the escaping modern man/woman away from real life, libarete him/her, and the magical enthusiasm of the child is play; that is, art

    Triacylglycerol and Phospholipid Classes of Capoettaumbla

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    In this study, seasonal changes in the muscle tissue, total lipid, and fatty acid composition of phospholipid (PL), triacylglycerol (TAG), and phospholipid classes of female Capoeta umbla were investigated. Fatty acid compositions of TAG and PL classes were found to be different in C. umbla muscle. Percentages of myristic acid, 16:1n-7, 18:1n-9, monounsaturated fatty acid (ΣMUFA), linoleic acid (18:2n6), and linolenic acid (18:3n-3) were found to be higher in TAG than the values determined in PL classes. In PL classes, 16:0, 18:0, arachidonic acid (20:4n-6, AA), EPA (20:5n-3), DHA (22:6n-3), and polyunsaturated fatty acid (ΣPUFA) were higher than TAG fraction

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