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    Quercetin ve Koenzim Q10'un sıçanlarda gentamisin kaynaklı nefrotoksisite üzerine etkileri

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    Aims: In this study, the effects of supplementary feeding during gestationand lactation period on birth and weaning weights of kids and milk yield ofdams in Kilis goats were investigated.Methods and Results: In the study, experimental goats were divided intothree groups as control group, short-term feeding (STF) group and longterm feeding (LTF) group. The control group was kept under breeder’smanagement conditions. Supplementary feed of 750 g/head/day weregiven to the goats from the last 20 days of gestation to 90th days after birthin the STF group, and from last 40 days of gestation to the end of lactationin LTF group. At the end of the experiment, the highest lactation periodwas 220.2 days in the LTF group, followed by STF and control groups (P<0.05). Likewise, in the LTF and STF groups, the lactation milk yield, whichwas determined as 466.2 and 426.3 liters respectively, was higher than thecontrol group (316.4 liters) (P <0.05).Conclusions: It was concluded that supplementary feeding duringgestation and lactation periods caused an increase in milk yield andlactation length of Kilis goats.Significance and Impact of the Study: At the end of study, it can be statedthat if supplementary feeding is made during gestation or lactation, milkyield characteristics of Kilis goats will be improved. Suckling period for thegoats is the period when pasture conditions are good. For this reason, evenin the goats managed only in the pasture, milk yield of mothers is sufficientfor multiple born kids.Amaç: Bu çalışmada Kilis keçilerinde, gebelik ve laktasyon dönemlerinde ek yemleme uygulamalarının doğum ve sütten kesim ağırlıkları ile anaların süt verimleri üzerine etkileri araştırılmıştır. Yöntem ve Bulgular Bu projede deneme materyali keçiler kontrol, kısa süreli besleme ve uzun süreli besleme grupları olarak üç gruba ayrılmışlardır. Kontrol grubu yetiştirici koşullarında yönetilmiştir. Kısa dönem besleme grubunda gebeliğin son 20 gününden başlayarak doğum sonrası 90. güne kadar, uzun süreli besleme grubunda ise gebeliğin son 40 gününden başlayarak laktasyon süresince keçilere günde 750 g/baş kesif yem verilmiştir. Deneme sonunda en yüksek laktasyon süresi 220.2 gün olarak uzun süreli besleme grubunda olmuş bunu kısa süreli besleme grubu ve kontrol grubu takip etmiştir (P <0.05). Benzer şekilde uzun süreli ve kısa süreli besleme gruplarında laktasyon süt verimleri sırası ile 466.2 ve 426.3 litre olarak belirlenmiş ve kontrol grubundan (316.4 litre) daha yüksek olmuştur (P <0.05). Genel Yorum: Çalışmada gebelik ve laktasyon dönemlerinde ek yemleme uygulamalarının laktasyon süresi ve süt veriminde artışa neden olduğu sonucuna varılmıştır. Çalışmanın Önemi ve Etkisi: Bu çalışma sonunda Kilis keçilerinde gebelik ve laktasyon dönemlerinde ek yemleme yapılırsa keçilerin süt verim özelliklerinin iyileşeceğini göstermektedir. Bölgedeki oğlaklar için süt emme dönemi mera şartlarının iyi olduğu zaman dilimindedir. Bu nedenle, hayvanlar sadece merada yönetilseler dahi, annelerin süt verimleri çoğuz doğan oğlaklar için yeterli olmaktadır

    Epicardial fat thickness is associated with oxidative stress index in cardiac syndrome X

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    AbstractAim: We aimed to investigate the relationship between oxidative parameters- total oxidant status (TOS), total antioxidant capacity (TAC), and oxidative stress index (OSI)- and EFT in patients with CSX. Without clinically significant coronary artery disease, cardiac syndrome X (CSX) is characterized by cardiac ischemia, and chest pain. However, there is some evidence about increased oxidative stress in CSX patients; the relationship between oxidative stress parameters and epicardial fat thickness (EFT) is not well established in this population.Material and Methods: : One hundred and twenty-two patients with normal coronary arteries (73 female, 49 males, mean age 56.71 ± 10.69 years) were enrolled in the study. The study population was divided into two groups according to their OSI. Oxidative stress index below the median was defined as the OSI low group and equal or higher than the median was defined as the OSI high group.Results: EFT was higher in the high OSI group than the low OSI group (6 (3.9 – 8.9) vs. 5.4 (0.56 – 7.2), p= 0.032). In bivariate correlation analysis EFT was positively correlated with OSI and TOS (r=0.242, p=0.036 and r=0.234, p=0.025 respectively). In binary logistic regression analysis, EFT was found to be an independent predictor of OSI.Conclusion: : In our study, EFT was independently associated with OSI in CSX patients. This finding suggests that EFT may be a marker of increased oxidative stress in CSX

    Interest of localpeople in gastronomy tourism and their food neophobia: Cases of Hatay and Gaziantep

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    The cuisine culture is a vital element of food-beverage experience in gastronomy tourism. In this sense, foods and beverages have constituted a major partof the culture in which they belong to and become a tool in acquiring knowledge and experience about the cuisine culture of a given location. The purpose of this study is to determine the interest of the local people in Hatay and Gaziantep, which safeguard their diverse cuisine culture in traditional ways and maintain their authenticity as UNESCO's Cities of Gastronomy, in gastronomy tourism and the extent of their food neophobia. As a part of this study, the questionnaires were applied by the researchers in Gaziantep and Hatay in 2019. Total of 565 questionnaires were evaluated. The data analysis was performed based on descriptive statistics such as arithmetic mean and standard deviation, as well as factor analysis, t-test and one-way analysis of variance.The results revealed that the people in both cities are highly interested in gastronomy tourism. It was found out that the food neophobia is highly neutral for the people of both Gaziantep (56.9%) and Hatay (63.0%). It was also revealed that some respondents (Gaziantep 36.4%, Hatay 32.7%) had food neophobia to a certain extent. On the other hand, the food neophobia turned out to be more common among male respondents than female respondents. In another finding, although the food neophobia level of the participants with high education level in Hatay was low, it was found that the food neophobia levels of the participants with high education level in Gaziantep were high. The results of the the respondents from Hatay corroborate the results of past studies. However, the results of the respondents from Gaziantep suggest the contrary compared to the past studies, and indicate that the less educated respondents are, the less food neophobia they tend to have. This shows that the effect of educational background on food neophobia has yet to be evident

    I. Dünya Savaşı’nda İngilizce Basında Yayımlanan Ermeni Propagandalarına Ait Bazı Örnekler

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    Bu çalışmada; I. Dünya Savaşı sırasında, Osmanlı Ermenilerinin, Osmanlı topraklarında kendi devletlerini kurma hayallerini gerçekleştirmek için İtilaf devletlerinin safında yer almalarının iç yüzü, dönemin önde gelen basın organlarında çıkan haberlerden örneklerle açıklanacaktır. ‘The Times’, ‘The New York Times’, ‘Leader’, ‘Daily Mercury’, ‘Daily Examiner’, ‘Examiner’, ‘The Ballarat Courier’, ‘Townville Daily Bulletin’, ‘Warwick Examiner and Times’, ‘Warracnabeal Herald’, ‘Mudgee Guardian and North-Western Representative’, ‘New Castle Morning Herald and Miners’ Advocate’ ve ‘Richmond River Express and Casino Kyogle Advertiser’ gibi gazetelerin sütunlarında yer alan Ermeni haberleri irdelenmiştir. Böylece tarihi olayların bir kesitini oluşturan 1915 olayları ve sonrası başta olmak üzere, Ermeni meselesine dolaylı veya doğrudan destek veren ülkelerin yaklaşımları ele alınmıştır. Dünya kamuoyunu Ermeni meselesi noktasında etkileyebilecek düzeydeki Amerikan, İngiliz ve Avustralya yerel/ulusal gazetelerinden seçilen örnekler (1912-1920) yıllarına dair veriler bu çalışmanın kapsamını oluşturmuştur. Çalışmanın amacı; “Zalim Türkler”, “mazlum Ermeniler” şeklinde uluslararası platformda bir hava estirilmeye çalışıldığının çarpıcı örneklerine yer verilerek, hakikatin İngilizce basında yazıldığı gibi olmadığını ortaya koymaktır. 1915 olaylarının İngilizce basında çarpıtılarak yer almasının en önemli sebebi; İngiliz hükümetine bağlı propaganda bürosunun özellikle Amerikan kamuoyunu etkileyerek “Müslümanlar Hıristiyanları katlediyor” diye yalan ve abartılı haberler üreterek Amerika Birleşik Devletleri’ni kendi saflarında savaşa ikna etme gayretlerinden kaynaklanmıştır. Bu haberler maalesef daha sonra “The Blue Book”a dönüşerek dünya kamuoyunda Ermeni propaganda malzemesinin temel dayanaklarından birini oluşturmuştur.In this study, the lowdown of the Ottoman Armenians taking sides with the Entente States in World War I in order to realize their dreams of establishing their own state in the Ottoman lands will be explained with examples from the news published in the leading press organs of the period. The Times’, ‘The New York Times’, ‘Leader’, ‘Daily Mercury’, ‘Daily Examiner’, ‘Examiner’, ‘The Ballarat Courier’, ‘Townville Daily Bulletin’, ‘Warwick Examiner and Times’, ‘Warracnabeal Herald’, ‘Mudgee Guardian and North-Western Representative’, ‘New Castle Morning Herald and Miners’ Advocate’ and ‘Richmond River Express and Casino Kyogle Advertiser’ are examined. Thus, the approaches of countries that directly or indirectly supported the Armenian matter, especially the events before and after 1915 which constitute a cross-section of historical events are discussed. The data regarding the years (1912-1920) obtained from news examples selected from American, British and Australian local / national newspapers that could affect the world public opinion in terms of the Armenian matter constituted the scope of this study. The aim of the study is to include striking examples of the effort to create a false international public opinion in the form of "Cruel Turks" and "oppressed Armenians, and to demonstrate that the reality was not as it was written in the English press. The most important reason for the presentation of a distorted version of the events of 1915 in the English press was that the British government's propaganda bureau aimed to influence particularly the American public opinion by producing false and exaggerated news such as "Muslims are slaughtering Christians" in an effort to persuade the United States to fight on their side. Unfortunately, these news examples were compiled and published in a book titled “The Blue Book” and became one of the main pillars of Armenian propaganda material to influence the world public opinio

    Türkiye’deki Dorycnium hirsutum (Fabaceae) taksonlarına sistematik katkılar

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    Abstract: Some interesting plant samples collected from Samandağ district of Hatay province were examined and it was determined that these specimens belong to Dorycnium hirsutum var. syriacum. Its status in the Flora of Turkey is mentioned as suspicious. In this study, it is stated that the Dorycnium hirsutum species should be divided into two distinct varieties as Dorycnium hirsutum var. hirsutum and Dorycnium hirsutum var. syriacum to investigate the morphological, taxonomic and palynological features of these taxa. Diagnostic characters and detailed descriptions of taxa and species identification key are given and IUCN categories are proposed.Yapılan arazi incelemeleri sırasında Hatay-Samandağ bölgesinde toplanan bazı bitki örneklerinin, Türkiye florasında varlığından şüpheli olarak bahsedilen Dorycnium hirsutum var. syriacum olduğu tespit edilmiştir. Bu çalışmada Dorycnium hirsutum türünün Dorycnium hirsutum var. hirsutum ve Dorycnium hirsutum var. syriacum olmak üzere iki varyeteye ayrılması gerektiği belirtilmiş, taksonların morfolojik, taksonomik ve palinolojik özellikleri araştırılmıştır. Taksonlara ait ayırt edici karakterler, ayrıntılı betimlemeler ile tür teşhis anahtarı verilmiş ve IUCN kategorileri önerilmiştir

    Hormonal profile of Mediterranean green turtles (Chelonia mydas)

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    The beaches of Turkey are important nesting habitats of Chelonia mydas sea turtles and the determination of their health and disease status is critical in sustaining healthy populations. Limited data currently exist on the hormone values required to determine the status of reproductive capabilities of sea turtles. This study aimed to collect basic data regarding their hormonal profile and set reference limits for the Mediterranean population. Forty-nine free-ranging C. mydas sea turtles were used in the study and were classified into 3 groups according to their age (hatchlings, juvenile, adult). Adult turtles were also grouped according to sex. Adult females were further divided into 3 seasonal groups (summer, spring, and autumn), based on the dates of blood sampling. Plasma testosterone, oestradiol, progesterone, thyroxine (T4), triiodothyronine (T3), thyroid-stimulating hormone (TSH), cortisol, and corticosterone levels were determined by ELISA method. Significantly higher levels were observed in oestrogen (P < 0.001), progesterone (P < 0.001), cortisol (P < 0.05), corticosterone (P < 0.05), T3 (P < 0.05), and T4 (P < 0.01) in the adult turtles when compared with the other groups. The highest levels of oestrogen (280.2 ± 39.34), progesterone (274.2 ± 29.4), cortisol (2.26 ± 0.36), and corticosterone (2.94 ± 0.53) were determined in the adult female turtles during the spring season. This data could be used to protect the population of this endangered species by taking precautions against diseases via determining their blood hormone levels and taking precautions against reproductive diseases. Further work is required, but this research can expand the knowledge on the basic blood biochemistry of Mediterranean green turtles

    Türkiye'de bir eşekte (Equus asinus Linnaeus, 1758) ilk Bovicola (Werneckiella) ocellatus (Piaget, 1880) (Phthiraptera: Ischnocera: Trichodectidae) olgusu

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    Abstract: In the clinical examination of a donkey, which brought to the Ownerless Animal Care and Rehabilitation Center of the Hatay Metropolitan Municipality due to neglecting and senility, local hair losses, ruffling and opacity were observed. A few louse specimens were detected on the hair shafts on the back of the donkey during the macroscopic examination. They were collected with a forceps, and preserved in a tube with alcohol 70%. Then they examined in detail in microscope, and identified as Bovicola ocellatus (Piaget, 1880). The presence of B. ocellatus on donkey has been reported for the first time in Turkey in this paper.Özet: Hatay Büyükşehir Belediyesi Sahipsiz Hayvan Bakım ve Rehabilitasyon Merkezi'ne yaşlılık ve bakımsızlık nedeniyle getirilen bir eşeğin klinik muayenesinde tüylerinin çok karışık ve matlaşmış olduğu, yer yer döküldüğü gözlenmiştir. Yapılan makroskobik incelemede eşeğin sırt bölgesindeki tüylerin dip kısımlarında bir kaç bit saptanmıştır. Bitler bir pens yardımıyla alınmış ve içinde %70'lik alkol bulunan bir tüpte saklanmıştır. Daha sonra mikroskopta ayrıntılı olarak incelenen örnekler Bovicola ocellatus olarak teşhis edilmiştir. Bu makaleyle B. ocellatus'un Türkiye'deki varlığı ilk kez bildirilmektedir

    Kırsal kalkınma aracı olarak coğrafi işaretler ve geleneksel ürünler: Medeniyetler şehri Hatay örneği

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    Aims: The province of Hatay is one of Turkey’s most important provinces with regard to its cultural richness and the variety of its local products, and in this study, an investigation is made of the current state of its geographical indications and traditional products, their potential, and their contribution to rural development. Methods and Results: In this study, products and potential products with a registered geographical indication of Hatay province were obtained from the data of relevant institutions, and in-depth interviews were held with experts on the topic in those institutions. Also, observations relating to the products were made in the relevant areas. As a result, it was found that although the potential for local products was very high, the levels of exploitation and awareness were low. Conclusions: In a globalising world, the increase in the importance of local values, the acquisition of value by local products and their contribution to rural development attract attention. In underdeveloped regions, in particular, traditional products can constitute an important opening for rural development and can create important areas of employment for women and young people. Significance and Impact of the Study: Developing the capacity of both the public and the private sector and especially cooperatives with regard to geographical indications and achieving producer and consumer awareness are important for rural development.Amaç: Bu çalışmada kültürel zenginliği ve yöresel ürünler çeşitliliği bakımından Türkiye’nin önemli illerinden biri olan Hatay ilinin coğrafi işaretler ve geleneksel ürünlerde mevcut durumu, potansiyeli ve kırsal kalkınmaya katkıları araştırılmıştır. Yöntemler ve Sonuçlar: Çalışmada Hatay ilinin coğrafi işaret tescili alan ürünleri ile potansiyel ürünleri ilgili kurumların verilerinden elde edilmiş ve kurumlarda konu uzmanları ile derinlemesine mülakatlar gerçekleştirilmiştir. Ayrıca, ürünlerle ilgili sahada gözlemler de yapılmıştır. Sonuç olarak yöresel ürün potansiyeli çok yüksek olmakla birlikte bunun kullanımı ve farkındalık düzeyi düşük olarak değerlendirilmiştir. Genel Yorum: Küreselleşen dünyada yerel değerlerin öneminin artması coğrafi işaretleri ve yöresel ürünleri değerli hale getirmekte ve kırsal kalkınmaya katkılarına dikkat çekmektedir. Özellikle az gelişmiş bölgelerde geleneksel ürünler kırsal kalkınma için önemli bir açılım oluşturacak, kadınlar ve genç nüfus için önemli bir istihdam alanı yaratabilecektir. Çalışmanın Önemi ve Etkisi: Coğrafi işaretler konusunda gerek kamu gerekse özel sektör ve özellikle de kooperatiflerin kapasite geliştirmesi, üretici ve tüketici farkındalığının gerçekleşmesi kırsal kalkınma açısından önemlidir

    Doğu Akdeniz koşullarında yetiştirilen kuraklığa dayanıklı ve hassas pamuk çeşitlerinin fotosentetik özelliklerin belirlenmesi

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    Aims: This study aimed to investigate the effects of different irrigation water levels on evapotranspiration, water use efficiency, stomatal conductance, photosynthesis rates and yields in 14 drought-sensitive and resistant cotton varieties. Methods and Results: The trial was carried out according to the random blocks experimental design pattern. The experimental study was conducted on ST 506, ST468, BA525, BA119, FLASH, SIOKRA L-22, TAM SPHINX, TAM 94L-25, PIMA S-7, TAMCOT-22, TAMCOT SP 21 S, TAMCOT SP 23, TAMCOT CAMD-ES and AKSEL cultivars. Evapotranspiration, water use efficiency, stomatal conductance, transpiration and photosynthesis rates and yields of the mentioned cultivars were determined. Photosynthesis rate, transpiration rate and stomatal conductance were measured only at the levels of full irrigation (I100) and 25% of the full irrigation (I25). Conclusions: The total numbers of irrigation done in the first and second years were four and six, respectively. The amount of irrigation water applied varied between 270 and 480 mm in the first year, and 298 and 520 mm in the second year. Yield and evapotranspiration increased depending on the amount of irrigation water applied. The highest and lowest yields were determined as 358 kg da-1 in Aksel cultivar and 555 kg da-1 in BA525 variety, respectively. On average, the photosynthesis rate was measured as 12,616 µmol m-2 s -1 for I100, and 7.549 µmol m-2 s -1 for I25. As the stomatal conductance increased, the yield also increased (0.093 mol m-2 s -1 for I25 and 0.182 mol m-2 s -1 for I100). Transpiration rate was determined as 2.947 mmol m-2 s -1 for I25 and 3.919 mmol m-2 s -1 for I100. The varieties did not significantly differ in terms of water stress. Aksel cultivar is droughtsensitive, whereas the others are drought-resistant varieties. Significance and Impact of the Study: The research revealed the physiological characteristics, plant water consumption and water use efficiency of 14 different cotton varieties widely grown in eastern Mediterranean conditions. And also, when the relationship of the mentioned parameters with yield was examined, the relationship between stomatal conductance and yield was found lower than the one between transpiration and photosynthesis rates

    Kulak küpesi takılan buzağılarda akut dönemde oksidatif stres değişimler

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    This study aimed to investigate the effects of ear-tagging on blood malondialdehyde (MDA), reduced glutathione (rGSH), Vitamin C (Vit C) levels, and glutathione peroxidase (GPx) activity in the acute period. Ear-tagged (with polyurethane ear-tag) animals consisted of nine healthy Holstein calves (2-3 months old). Blood samples were taken just before ear-tagging (baseline), at the 20th min, on the 3rd day, and 8th day after the ear-tagging procedure. Six Holstein calves were involved the sham group. In ear-tagged animals, plasma MDA levels increased on the 3rd day compared to baseline values (p<0.01) and returned to baseline values on the 8th day, whereas no change was found in the sham group. In ear-tagged animals, plasma rGSH levels increased at the 20th min, 3rd day, and 8th day (p<0.001) in comparison to baseline values, which in the sham group, there was no change. In ear-tagged animals, erythrocyte rGSH levels on the 3rd and 8th days were higher compared to baseline and 20th min level (p<0.01). In the sham group, the 3rd and 8th day erythrocyte rGSH levels increased compared to baseline values (p<0.01). In ear-tagged animals, the 20th min, 3rd day, and 8th day erythrocyte GPx activities were lower than the baseline values (p<0.001), whereas in the sham group, no change was observed. While Vit C levels increased progressively in the sham group (p<0.05), this increase was not observed in the ear-tagged group. In conclusion, ear-tagging was found to cause oxidative stress and increase antioxidant requirement in calves.Bu çalışmanın amacı kulak küpelemenin akut dönemde kan malondialdehid (MDA), redükte glutatyon (rGSH), vitamin C (Vit C) düzeyleri ile glutatyon peroksidaz (GPx) aktivitesi üzerine etkilerinin araştırılmasıdır. Çalışmanın deney grubunu, kulak küpeleme (poliüretan kulak küpesi ile) yapılan dokuz adet buzağı (2-3 aylık yaşta) oluşturdu. Kan örnekleri kulak küpeleme işleminden hemen önce (temel seviye), kulak küpeleme sonrası 20. dakika, 3. gün ve 8. gün’de alındı. Ayrıca, belirtilen zamanlarda sadece kanları alınan altı adet Holstein ırkı buzağı da sham grubu olarak kullanıldı. Kulak küpeli buzağılarda 3. gün MDA seviyeleri temel seviyelere göre yükselirken (p<0,01), 8. günde tekrar temel seviyelerine indi. Sham grubunda ise MDA düzeyleri yönünden bir değişiklik gözlenmedi. Kulak küpeleme grubunda plazma rGSH seviyeleri 20. dakika, 3. gün ve 8. günde temel düzeylere göre arttı (p<0.001); ancak, sham gurubunda bir değişim gözlenmedi. Kulak küpeli buzağılarda eritrosit rGSH seviyeleri 3. ve 8. günlerde, 20. dakika ve temel seviyelere göre yüksek olarak belirlendi (p<0.01). Sham grubunda ise 3. ve 8. gün eritrosit rGSH seviyeleri temel seviyelere nazaran yüksek olarak belirlendi (p<0.01). Kulak küpeleme grubunda eritrosit GPx aktiviteleri 20. dakika, 3. gün ve 8. gün’lerde temel seviyelere kıyasla düşük (p<0.001) olmasına rağmen, sham grubunda bir değişim göstermedi. Sham grubunda Vit C seviyeleri giderek artmasına rağmen (p<0.05), kulak küpeli hayvanlarda bu artış görülmedi. Sonuç olarak kulak küpelemenin buzağılarda oksidatif strese neden olarak antioksidan ihtiyacı arttırdığı düşünüldü

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