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Recurrent penile and oral aphthosis revealing an LGL T-cell lymphoproliferative disorder
No full textInternational audienceLarge granular T-cell lymphoproliferative disorders are rare and often silent, making diagnosis difficult. We report a 26-year-old man with recurrent oral and genital aphthous ulcers initially diagnosed as idiopathic bipolar aphthosis. Colchicine therapy induced neutropenia, prompting investigations that revealed a clonal large granular T-cell lymphoproliferative disorder. This case underscores the importance of considering hematological disease when recurrent mucosal aphthosis is associated with unexplained neutropenia
Spatial predictions and uncertainty maps of global fallout radionuclides (137Cs and 239+240Pu) for the Southern Hemisphere
No full textInternational audienceOverview This repository contains high-resolution (1 km) spatial datasets for global fallout radionuclides across the Southern Hemisphere (extending to 20°N). The data includes spatial predictions, uncertainty estimates, and model applicability assessments for Cesium-137 () and Plutonium-239+240 () inventories in soil. Associated Publication These datasets support the research presented in the following study: "Radioactive fallout legacy of nuclear tests in soils of the Southern Hemisphere" Submitted to: Science Advances Technical Specifications Spatial Resolution: 1 km (30 arc-seconds) Coordinate Reference System (CRS): [WGS 84] Units: [Bq/m²] and [% for CV] Data Content For both and , the repository provides: Prediction Maps (.tif): Spatial distribution of radionuclide inventories. Uncertainty & CV Maps (.tif): Standard deviation and Coefficient of Variation for reliability assessment. Area of Applicability (.shp): Vector masks identifying the reliable model domain (Gridcode 1 = Applicable). To cite the database, please use: Avcıoğlu, A., Dicen, G., Gupta, S., Alewell, C., Evrard, O., Sabatier, P., Angot, H., Vandromme, R., Cerdan, O., & Meusburger, K. (2026). Radioactive fallout legacy of nuclear tests in soils of the Southern Hemisphere. Science Advances. (Submitted). Documentation Please refer to the README.txt (or README.md) file included in this repository for detailed metadata, file structures, and usage instructions
Inter-Satellite LED-Based Optical Wireless Communications for CubeSats
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Autoencoders reveal polyunsaturated fatty acids (PUFA)-Related metabolic signature linked to cancer risk
No full textInternational audienceWorld Cancer Research Fund (IIG_FULL_2022_013)
Antibioprophylaxis in thoracic surgery, thoracic endoscopy, and interventional radiology
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Women, menopause, hormone therapy, and cardiovascular disease: what WHI still teaches us in 2025, and where are we now?
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Protocol for a cohort comparison treatment study evaluating the efficacy of a dimensional adaptation of GPM (GPM-extended) compared to a classic outpatient GPM treatment for patient fulfilling criteria for BPD: the EPSYLIA project
No full textInternational audiencePersonality disorders (PD) are common and debilitating psychiatric conditions, often characterized by severe interpersonal and self-dysfunction. Borderline personality disorder (BPD) is the most studied PD, with treatments like Good Psychiatric Management (GPM) demonstrating effectiveness. To address the current state of the personality disorder field, where most evidence-based treatments have been developed using a categorical approach, while the most empirically supported approach is the dimensional one, we developed an adaptation of GPM (GPM-extended) integrating concepts of dimensional personality dysfunction into an established therapeutic framework. This prospective “here-there” study will compare GPM-extended with standard GPM in two outpatient facilities. This methodological choice is due to organizational and institutional limitations. Participants (≥18 years) meeting BPD criteria per the SCID-II will be included. The GPM-extended group incorporates a dimensional diagnostic framework focusing on three personality dilemmas (rejection/abandonment fears, self-esteem dysregulation, and perfection/control issues), with tailored psychoeducation and treatment priorities. The standard GPM group will follow the validated GPM protocol, emphasizing interpersonal hypersensitivity and standard psychoeducation. Both groups will receive weekly individual therapy and group interventions for one year. Between-group differences at 1-year follow-up will be assessed using multiple regression models adjusted for baseline scores. The primary outcome is the change in BPD symptom severity (ZAN-BPD). Secondary outcomes include personality functioning, traits, and various clinical dimensions such as impulsivity, emotional regulation, and social functioning. All patients having initiated the program and having initial data will be included in the analysis, with multiple imputations for missing data and sensitivity analyses planned. Altogether, this study seeks to evaluate the feasibility and efficacy of integrating dimensionality into GPM, offering a pragmatic pathway to improve PD treatment and bridging gaps between evidence-based conceptualizations and treatments of PD. Clinical trial registration ClinicalTrials.gov, identifier NCT06913738
Intentions, practices, and social representations regarding breastfeeding among women experiencing social disadvantage: findings from the qualitative component of the ECAIL trial
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Python code for reading and processing EarthCARE ATLID L1B data
No full textInternational audiencePython code for reading and processing EarthCARE ATLID L1B dataThe code reads EarthCARE ATLID Level 1B data and produces daily/zonally averaged vertical profiles of optical and meteorological parameters on a regular latitude/altitude grid of 1 degree and 500 m respectively (L3 product). The data are saved into NetCDF files for each day