Helmholtz Institute Freiberg for Resource Technology
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Data Publication: Protein Enrichment by Foam Fractionation: Experiment and Modeling
No full textThis work investigates the enrichment of bovine serum albumin (BSA) protein through foam fractionation. Here, we performed experiments using BSA and measured the recovery and grade of the extract. Additionally, an unsteady-state simulation of the protein foam fractionation process was carried out by numerically solving the liquid drainage equation in the foam. Thereby, the extracted liquid volume and protein concentration were calculated. Required quantities such as foam stability, interface coverage or bubble size distribution were measured in corresponding experiments and were fed into the model. The experiments showed that the foam coalescence accelerates the liquid drainage leading to dryer extract and higher protein enrichment. The modeling also reproduced the liquid recovery and extract concentration of the foam fractionation tests within a reasonable error range. The modeling solely relies on experimental inputs and does not require any tuning parameters. It can be further used for optimization or up-scaling of protein foam fractionation
Evaluation of raw data from THz source.
No full textThe radiation source ELBE (Electron Linac for beams with high Brilliance and low Emittance) at the Helmholtz Centre Dresden Rossendorf (HZDR) can produce several kinds of secondary radiations. THz radiation is one of them and can be used with a typical pulse frequency of 100 kHz as a stimulation source for elementary low-energy degrees of freedom in matter. It was used in the "Phase-resolved Higgs response in superconducting cuprates" publication (DOI: 10.1038/s41467-020-15613-1). The raw data for this publication can be accessed on RODARE (DOI: 10.14278/rodare.277) and will be used to reproduce the figures from the publication. This Jupyter notebook enables the user to handle the raw data from an TELBE THz experiment. To sample the whole THz wave the laser path length is modified by moving specific mirrors. The raw data contains for each mirror position a binary file storing the signal spectra and a folder with gray scaled tiff files storing the jitter timing. Parts of the code are parallelized and can run on multiple cores. The execution time on a single core is roughly 15 min after downloading and extracting a 20 GB zip file
Data to "Application of a fluorescence anisotropy-based assay to quantify transglutaminase 2 activity in cell lysates"
No full textPrimärdaten zum FA-Assay, activity-based ELISA und ELIS
Data publication: Density functionals with spin-density accuracy for open shells
No full textData for the figures of the main paper (https://aip.scitation.org/doi/10.1063/5.0071991) and supplementary information, arranged by figure number.
Notes:
- A few energies are given as identically zero. These are not actually zero but did not converge.
- All data is given in the units in which it appears in the paper, and columns are labelled using the same notation as in the paper
Data publication: Non-invasive assessment of locally overexpressed human adenosine 2A receptors in the heart of transgenic mice
No full textPET data, mice; i.v. administration of [18F]FLUDA with and without pre-administration of istradefyllin
Slice2Volume: Fusion of multimodal medical imaging and light microscopy data of irradiation-injured brain tissue in 3D.
No full textThe dataset contains comprehensive image data for a total of nine mice, which underwent normal tissue brain irradiation with 90 MeV protons.
In particular, the image data comprise cone-bem computed tomographies (CBCT), Monte Carlo beam transport simulations based on those CTs, regular magnetic resonance imaging (MRI) follow-up (≥ 26 weeks), a co-aligned DSURQE mouse brain atlas and scanned whole-brain tissue sections with histochemical and immunofluorescent markers for morphology (H&E), cell nuclei (DAPI), astrocytes (GFAP), microglia (Iba1), the intermediate filament protein Nestin, proliferation (Ki67), neurons (NeuN) and oligodendrocytes (OSP).
The volumetric image data (i.e. CBCT, MRI and brain atlas) were co-aligned using the ImageJ plugin Big Warp. The CBCT data was used as spatial reference to allow for mask-based, slice-wise alignment of CBCT and light microscopy image data in 3D with the scriptable registration tool Elastix.
We provide the data in raw format and as aligned data sets, as well as their spatial transformations.Note: There are ongoing corrections taking place with the B6 mouse strain data (P2A_B6_M1, P2A_B6_M2, P2A_B6_M6, P2A_B6_M10). If you are interested in working with these data, please wait for the new version to be uploaded or contact the authors of https://doi.org/10.1016/j.radonc.2023.109591
Chunked zip: The histological data are stored as chunked .zip files (*.zip.001 - *.zip.0XX). In order to unpack the data, download all chunks into the same directory, then unpack
Data publication: Improved calculations of mean ionization states with an average-atom model
No full textData for our paper "Improved calculations of mean ionization states with an average-atom model" (arXiv)
For details about the data, please see the README file after unpacking the folder, and this GitHub repository
Data: Study of a possible silicon photomultiplier based readout of the large plastic scintillator neutron detector NeuLAND
No full textThe NeuLAND (New Large-Area Neutron Detector) plastic scintillator based time of flight detector for 0.2-1.6 GeV
neutrons is currently under construction at the Facility for Antiproton and Ion Research (FAIR), Darmstadt, Germany.
In its final configuration, NeuLAND will consist of 3,000 2.7 m long plastic scintillator bars that are read out on each
end by fast timing photomultipliers.
Here, data from a comprehensive study of an alternative light readout scheme using silicon photomultipliers (SiPM)
are reported. For this purpose, a typical NeuLAND bar was instrumented on each end with a prototype of the same
geometry as a 1” photomultiplier tube, including four 6×6 mm2 SiPMs, amplifiers, high voltage supply, and micro-
controller.
Tests were carried out using the 35 MeV electron beam from the ELBE superconducting linac with its ps-level time jitter in two different modes of operation, namely parasitic mode with one electron per bunch and single-usermode with 1-60 electrons per bunch, using Acqiris fast digitizers. In addition, offline tests using cosmic rays and the NeuLAND data acquisition scheme were carried out.
Typical time resolutions of σ≤120 ps were found for ≥ 95% efficiency, improving on previous work at ELBE and exceeding the NeuLAND timing goal of σ <150 ps. Over a range of 10-300 MeV deposited energy in the NeuLAND bar, the gain was found to deviate by ≤ 10% (≤20%) from linearity for 35μm (75μm) SiPM pitch, respectively, satisfactory for calorimetric use of the full NeuLAND detector. The dark rate of the prototype studied was found to
be 70-200 s-1, comparable with the unavoidable cosmic-ray induced background.
The dataset contains the with the Acqiris Digitzier recorded waveforms and analysis scripts for interpretation of the data. Also GEANT4 simulations of the light propagation in a NeuLAND bar and the electron beam propagation are included
Data for: Spectral X-ray Computed Micro Tomography: 3-dimensional chemical imaging
No full textThe files show the data we used for the publication