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Topographic and bathymetric lidar, orthophotos, sonar, and GPR data of and along the Devils River from Juno to Lake Amistad, Texas (Imagery 10 of 16)
No full textData collected in and along the Devils River from Juno to Lake Amistad, Texas include: Topographic and bathymetric lidar data in both 1m raster (BIL) and point (LAS) formats; Orthophotos in geoTiff format; and an index map (SHP) depicting data extents. For an area of more detailed study--a pool two kilometers long from Finnegan Springs to Dolan Falls--we're providing Sonar and GPR point (LAS) data and a 1m composite (lidar + GPR) raster (BIL) dataset. 0README.txt provides additional information
DOUAR software for "Development of strain-partitioning regional structures facilitated by mechanical heterogeneity and arcuate wedge shape in the Himalaya"
No full textThis repository contains the software DOUAR used in the modelling work presented in the article "Development of strain-partitioning regional structures facilitated by mechanical heterogeneity and arcuate wedge shape in the Himalaya" by Suoya Fan, Michael Murphy and David Whipp
Replication Data for: News Video Narrative on the Web
No full textThis dataset is the result of a content analysis of video narrative style for various news organizations on the web
Slavery in Early Mexico: A Dataset Identifying the Enslaved Persons on the Estates of Hernando Cortés
No full textA dataset of personal names and descriptions of African and Indigenous people who were enslaved on the estates of Hernando Cortés
RDM_Scoping_Empirical Studies
No full textThis dataset is for a scoping review study about data management training in academic libraries
HYSPLIT model comparison manuscript
No full textVarious Excel data sheets/files containing meteorology and hydrocarbon data used in the manuscript "Testing HYSPLIT plume dispersion model performance using regional hydrocarbon monitoring data during a gas well blow-out
Sucesión del mayorazgo de Don Antonio de Echaide y Doña Maria de Tovar Godinez, circa 1771
No full textApuntes detallados sobre la sucesión del mayorazgo fundado por Don Antonio de Echaide y Doña Maria de Tovar Godinez. El documento lista cada sucesor(a), su pareja, y sus hijos y hijas y incluye clausulas de testamentos y otros documentos legales. Por falta de sucesores y por enlace matrimonial, el Mariscal de Castilla, Don José Antonio de Luna Gorráez y Malo, asumió el título del mayorazgo. —— Detailed notes on the succession of the mayorazgo (landed estates) founded by Don Antonio de Echaide y Doña Maria de Tovar Godinez. The document lists each successor, their spouse, and their children, and it includes clauses from testaments and other legal documents. Due to a lack of successors and marriage, the Marshal of Castile, Don José Antonio de Luna Gorráez y Malo, assumed the ownership of the estates. 6 f. (12 p.) (XVIII century
Muscle proteome changes during cancer
No full textINTRODUCTION. Both cancer and cancer associated therapies (CAT; including chemotherapy or concurrent chemoradiation) disrupt cellular metabolism throughout the body, including the regulation of skeletal muscle mass and function. Adjunct testosterone therapy during standard of care chemotherapy and chemoradiation modulates CAT-induced dysregulation of skeletal muscle metabolism and protects lean body mass during CAT. However, the extent to which the skeletal muscle proteome is altered under these therapeutic conditions is unknown.
OBJECTIVE. We probed the skeletal muscle proteome of cancer patients as an ancillary analysis following a randomized, double-blind, placebo-controlled phase II trial investigating the effect of adjunct testosterone on body composition in men and women with advanced cancers undergoing CAT.
METHODS. Men and women diagnosed with late stage (≥IIB) or recurrent head and neck or cervical cancer who were scheduled to receive standard of care CAT were administered an adjunct 7 week treatment of weekly intramuscular injections of either 100 mg testosterone (CAT+T, n = 9; 3M/6F) or placebo/saline (CAT+P, n = 10; 7 M/3F). Biopsies were performed on the vastus lateralis before (PRE) and after (POST) the 7 week treatment. Extracted proteins were separated with 2-dimensional gel electrophoresis (2DE), and subjected to analyses of total protein abundance, phosphorylation and s-nitrosylation. Proteoforms showing significant fold differences (t-test p ≤ 0.05) between PRE and POST timepoints were identified by mass spectroscopy (MS), and lists of altered proteins were subjected to Gene Set Enrichment Analysis (GSEA) to identify affected pathways.
RESULTS. A total of 756 distinct protein spots were identified. Of those spots, 102 were found to be altered in terms of abundance, phosphorylation, or s-nitrosylation, and identified by MS analysis to represent 59 unique proteins. Among the biological processes and pathways identified, CAT+P impacted muscle contraction, catabolic processes, and oxygen transport, while CAT+T impacted transcription regulation, muscle differentiation, muscle development, and contraction.
CONCLUSIONS. Cancer and CAT significantly altered the skeletal muscle proteome in a manner suggestive of loss of structural integrity, reduced contractile function, and disrupted metabolism. Proteomic analysis suggests that the addition of adjunct testosterone minimized the structural and contractile influence of cancer and its associated therapies
Topographic and bathymetric lidar, orthophotos, sonar, and GPR data of and along the Devils River from Juno to Lake Amistad, Texas (Imagery 03 of 16)
No full textData collected in and along the Devils River from Juno to Lake Amistad, Texas include: Topographic and bathymetric lidar data in both 1m raster (BIL) and point (LAS) formats; Orthophotos in geoTiff format; and an index map (SHP) depicting data extents. For an area of more detailed study--a pool two kilometers long from Finnegan Springs to Dolan Falls--we're providing Sonar and GPR point (LAS) data and a 1m composite (lidar + GPR) raster (BIL) dataset. 0README.txt provides additional information