684 research outputs found
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Stream Pedagogy Dataset
No full textThis is the dataset for Carlson Mazur, Waters, and Combs. (2024). Developing community partnerships to supplement water-quality data in support of urban watershed management
Stress, Resilience, and Coping: A Cross-Sectional Study of Black Male Osteopathic Medical Students’ Experiences in Medical School
No full textThis quantitative study investigated stress, coping, and resilience among Black male osteopathic medical students (BMOMS), focusing on the unique challenges that affect their academic success, mental and physical health, and professional development. This study was contextualized within the shifting demographics of U.S. osteopathic medical schools and the underrepresentation of Black males. Utilizing Moos’ Integrative Model of Stress and Coping, survey data from BMOMS (n = 85) were analyzed through descriptive statistics, correlations, and multiple linear regressions. Research questions addressed BMOMS’ specific stressors, the relationship between resilience and coping, and the influence of demographic variables. Out of 101 initial survey responses, 85 valid responses were included after excluding incomplete or ineligible submissions. Most participants were between 21-30 years old (70.6%), heterosexual (76.5%), and received financial aid (91.8%). Major stressors identified included financial pressures, academic workload, and social dynamics. All identified stressors showed significant positive correlations with overall stress levels (p \u3c .05). Resilience, measured by the CD-RISC-10, and coping, measured by the BRCS, were highly correlated (r = .83, p \u3c .001). While demographic variables collectively did not significantly predict stress, resilience, or coping, specific demographic factors did influence stress levels. Bisexual participants experienced higher stress (B = 22.92, p = .016) compared to heterosexual participants. Those married (B = 31.90, p = .003) or in relationships (B = 15.49, p = .029) also experienced higher stress, whereas having health insurance was associated with lower stress levels (B = -22.71, p = .003). Income significantly predicted resilience and coping, with higher income ranges linked to higher scores. These findings offer insights for medical institutions to increase support for BMOMS
Gonadal Absence of pig-1: Exploration of pig-1 in the Gonad of Caenorhabditis elegans
Get PDFCaenorhabditis elegans are model organisms frequently studied to better understand biological processes. They have short life spans and produce a large number of progeny. Additionally, many of their molecular development processes can be found in human, providing insight into cell death and cell fate. In this project, our research aims to create a triple mutant strain to test the importance of the pig-1 gene in the gonad of C. elegans. This strain carries the following alleles: ckb-3::degron; him-8; gfp::pig-1. The pig-1 gene has been previously studied in neuroblast cells in C. elegans and is required for asymmetrical division, resulting in one neural precursor and one apoptotic cell. The gfp::pig-1 strain was made by a previous undergraduate student Peyton Young. The him-8 gene, when mutant, leads to males making up approximately ~30% of the population. In comparison, males are approximately 0.2%-0.5% of the wild-type population. mRNA transcripts of the pig-1 gene have previously been shown to be enriched in the male gonads. Therefore, the him-8 mutant allele will allow us to phenotypically study the gonads of the male animals. Finally, ckb-3::degron is used to degrade GFP and proteins fused to it. The ckb-3::degron gene allows for the degradation of only gonadal GFP by ubiquitination because the ckb-3 promoter drives the degron to only be expressed in the gonad. The pig-1 gene is essential for the viability of the animal in other tissues and would lead to the animal\u27s death if removed from the whole animal. The triple mutant strain will allow us to observe what will happen to gonad development and function if pig-1 is removed from the gonad in both male and hermaphrodite worms. Therefore, I will analyze the triple mutant worm to see how the gonad is affected by the absence of the PIG-1 protein. This will be done by observing the triple mutant worms and noting any physical or behavioral abnormalities compared to worms containing gfp::pig-1, but not the ckb-3::degron
