2270 research outputs found
Sort by
The Influence of Circadian Rhythms on ICU Delirium
No full textProblem - It has been found that up to 80% of all mechanically ventilated ICU patients experience delirium (Ali, 2022). ICU delirium is an alteration in normal circadian rhythms while hospitalized which leads to confusion and mood abnormalities. To maintain circadian rhythms, it is important to maintain sleep and wake cycles, as well as sleep hygiene.
Purpose – The purpose of this study is to explore if patients who receive daily circadian rhythm interventions, such as maintaining pre-admission sleep patterns, have reduced rates of ICU delirium compared to those who receive standard care.
Methods – A mixed methods, quasi-experimental design will be used. Participants will be patients, ages 20-50, admitted to a 50-bed ICU unit. The study will compare pre-admission sleep patterns, CAM-ICU, and RASS assessments of patients receiving daily circadian rhythm interventions to those who do not receive it.
Conclusion – Interventions to maintain the circadian rhythm and sleep schedule of ICU patients should be used to prevent ICU delirium (Li et al., 2023). Further studies on prevention of ICU delirium including pharmacological and nonpharmacological interventions should be explored in future research to improve patient health
The Effects of an Educational Program on Organ Donation
No full textAbstract
Problem: There are currently over 103,000 people waiting to receive an organ donation but there are only about 23,000 organ donors. This leads to many patients dying while waiting to receive an organ.
Purpose: The purpose of this study is to determine if further education on organ donation for nurses can improve the likelihood of safe organ donation. Through this education, researchers will find an improvement of communication with family from the nurse on what to expect.
Methods: A quasi experimental design will be used within an intensive care unit. ICU nurses who volunteer to receive organ donation education will be included in the study. Life Bank will provide the education session. In this session, nurses are taught to recognize the signs of a potential organ donor and how to start the process of contacting Life Bank. The number of organ donations on the unit 6-months prior to the education and 6-months following education will be compared.
Conclusion: The implementation of education can improve rates of organ donation. Education implemented in intensive care units may be one method to combat the low number of organ donations
Active Ada: One Step at a Time
No full textChronic disease is a top priority in Hardin County as identified in the 2017-2020 Hardin County Community Health Improvement Plan (CHIP). This term includes conditions such as heart disease, diabetes, and asthma, and related risk-factors such as obesity, hypertension, high cholesterol, as well as behaviors closely associated with these conditions like nutrition, physical activity, and tobacco use. This study will investigate the impact of a walking program on chronic disease state risk factors within adults at least 18 years old in Ada, Ohio.
Through collaboration with the Ada Schools and Healthwise Pharmacy, baseline screening will be conducted to collect participants’ initial blood pressure, blood glucose, cholesterol, height, and weight at the end of March 2024. This baseline screening will serve as a kick-off event for an 8-week walking program. Participants will be encouraged to become more physically active during this time with support from members of the Rural and Underserved Health Scholars Program.
Results are anticipated to become available in the Fall of 2024
Exposure to the Trier Social Stress Test enhances central detail memory, reduces false memory, and results in intrusive memories that last for days
Get PDFRecent work has used a modified version of the well-known laboratory stressor, the Trier Social Stress Test (TSST), to study participant memory for a stressful experience. The paradigm is useful because, unlike most studies examining stress effects on memory, it allows investigators to measure what participants remember about the stressor, not unrelated information. It also presents an opportunity to model other stress-related symptoms, such as intrusive memories, but these have yet to be assessed with this paradigm. Intrusive memories have been notoriously difficult to measure in laboratory settings; most of this research involves participants watching arousing videos and subsequently reporting any intrusions they experience. However, measuring intrusive memories that result from arousing videos is quite dissimilar from measuring intrusive memories that result from a stressful event. Thus, we aimed to replicate and extend previous work by examining the impact of TSST exposure on (1) participant memory for the stressful event, (2) false memories of the stressful event, and (3) intrusive memories related to the stressful event.
Healthy undergraduate students were exposed to the TSST or the friendly-TSST (f-TSST). The TSST required participants to deliver a ten-minute speech in front of two lab panel members as part of a mock job interview; the f-TSST required participants to casually converse with panel members about their interests and hobbies. In both conditions, the panel members interacted with (central) or did not interact with (peripheral) several objects sitting on a desk in front of them. Participants’ heart rate, blood pressure, and anxiety levels were assessed before and after the TSST or f-TSST, and saliva samples were collected to assay for cortisol and alpha-amylase. The next day, participants’ memory for the objects that were present on Day 1 was assessed with recall and recognition tests. We also quantified participants’ intrusive memories for each task by having them complete an intrusive memory questionnaire on Days 2, 4, 6, and 8. Participants exposed to the TSST exhibited greater recall of central objects and fewer falsely recalled objects than participants exposed to the f-TSST. Most importantly, participants exposed to the TSST reported a greater number of intrusive memories related to the speech task. Some measures of intrusive memories in this group persisted for several days after stress exposure. Collectively, our work demonstrates that the modified TSST paradigm is a useful tool to not only study what participants remember about a stressful event but to also investigate characteristics of intrusive memories that may ensue
ELIMINATING DISCRIMINATION AND VIOLENCE AGAINST INDIGENOUS WOMEN:A CONSTITUTIONAL IMPERATIVE IN BANGLADESH
Get PDFState ex. rel. Internatl. Ass\u27n of Fire Fighters, Local 1536, AFL-CIO v. Sakacs, 224 N.E.3d 1110
Get PDF
FDA Approval of Zuranolone: A Breakthrough Treatment for Postpartum Depression
Get PDFPostpartum depression (PPD) is a serious medical condition that increases the risk of postpartum mortality and affects the ability of a postpartum individual to take care of their newborn. Until 2023, intravenously-administered brexanolone was the only Food and Drug Administration (FDA)-approved medication for PPD. Brexanolone’s route of administration poses significant barriers to accessibility and convenience. Other treatment options, such as psychotherapy and antidepressants, often require long-term commitment and may not provide rapid relief for severe symptoms. In August 2023, the FDA approved zuranolone as an oral medication for PPD, which enhances treatment accessibility and offers patients a more flexible, outpatient option. Findings from multiple clinical trials demonstrate zuranolone’s effectiveness in rapidly reducing PPD symptoms and producing significant improvements in mood and functionality within days. As a result, zuranolone represents a major advancement in PPD treatment and a promising alternative to traditional therapies for PPD patients. This review will discuss the pathophysiology of PPD, the current treatment options, challenges with the current treatment of PPD, the mechanism of action of zuranolone, pivotal clinical trials that played a role in zuranolone’s approval, the benefits and adverse effects associated with zuranolone, and future directions concerning the use of zuranolone in treating PPD
Primaries and Caucuses
Get PDFThe 2024 election will be an important one for voters across the United States as citizens will cast their ballots to choose who will serve as America’s next president. While many are anticipating a rematch between incumbent President Joe Biden and former President Donald Trump, a long road stands between now, the debate stage, and the ballot box. Before voters cast their ballots in the general election they must first select who will earn the nomination to be on that ballot when the time arrives. While Article II, Section I of the United States Constitution details the procedures for electing the president, it does not provide an answer to how we nominate the individuals we elect for president. Under our current two-party system, nominating presidential candidates is determined by primaries, caucuses, delegates, and ultimately Convention votes