International Medical Publisher Journals (iMedPub)
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The role of antifungal drugs in the management of denture-associated stomatitis
Get PDFBackground: Denture-associated stomatitis is a chronic infection of the oral cavitythat may be associated with a number of bacterial and candidal organisms aswell as some predisposing factors. Its management may prove to be difficult if thetreatment plan was not comprehensive in addressing all the factors involved in itsetiology. The aim of this review is to underline the effectiveness of antifungal drugsin the management of denture-associated stomatitis according to our personalexperience and the recently published literature.Methods: Articles were obtained from pubmed as well as by a hand search.Denture stomatitis and antifungal were used as keywords. Only articles writtenin English and which were published starting from the year 1990 were included.Conclusions: Antifungal drugs certainly have a place in the management ofdenture-associated stomatitis. However, their use should be called upon after thecontrol of factors known to cause this infection. Denture and oral hygiene, andmanagement of adverse medical conditions should be the primary goal of treatment.This should go hand in hand with the application of topical antifungal agentsparticularly those in the cream or gel form for better patients’ compliance
Characterization of Ag Nanoparticles Produced by White-Rot Fungi and Its in vitro Antimicrobial Activities
Get PDFBiosynthesis of Ag nanoparticles (AgNPs) with diameter ranging 50 to 80 nm is achieved using the white-rot fungi, Schizophyllum commune and Pycnoporus sanguineus. AgNPs were formed when the fungal mycelia and the supernatant reacted with AgNO3 after 5 days of incubation period. The synthesized nanoparticles were determined using analytical tools such as UV-vis spectrophotometer, and transmission electron microscopy. Results indicated that the UV-visible spectrum of the aqueous medium for S. commune and P. sanguineus showed a peak at 420 nm, which corresponded to the plasmon absorbance band of AgNPs. The antimicrobial properties of the synthesized AgNPs against Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Aspergillus niger and Candida albicans were also investigated using disc diffusion assay. Minimum inhibition concentration, minimum bacterial concentration and minimum fungicidal concentration are also identified using 96-well microtitre plate. It was found that AgNPs synthesized by the Malaysian white-rot fungi has the ability to act as an effective antibacterial agent
Highly Resistant Yersinia enterocolitica Isolated from Dairy Based Foods in Lebanon
Get PDFYersinia is small rod shaped, gram negative coccibacilli known as a food borne pathogen that may cause intestinal and systemic diseases known as yersiniosis. It has been reported that it may be transmitted by eating contaminated dairy foods. This study aims at evaluating the presence of Yersinia enterocolitica in Lebanese three dairy based foods which include Kishk, Shankleesh and Baladi cheese and reporting their susceptibilities to commonly used antimicrobial agents. In total, sixteen Y. enterocolitica isolates were recovered and subjected to relevant biochemical tests and finally identified by API system.  Eleven of those isolates were from Baladi cheese, three from Shankleesh and two from Kishk. The API results confirmed their identity, and were then subjected for susceptibility testing against: chloramphenicol (30µg), trimethoprim/ sulfamethoxazole (1.25µg+23.75µg), gentamicin (10µg), ciprofloxacin (5µg), nalidixic acid (30µg), Kanamycin (30µg) and streptomycin (10µg). Surprisingly, all the tested Y. enterocolitica isolates showed high rates of resistance to all the antimicrobials used with highest resistance to kanamycin (81.2%) and streptomycin (87.5%). The data showed that the antimicrobial resistance levels exceeded by far all the levels reported elsewhere. Based on the data, it may be concluded that dairy based foods in Lebanon, especially cheese that is prepared under unaccepted conditions, not abiding by proper hygienic practices. This might be the cause of a public health hazard, as cheese might act as a potential vehicle for the transmission of many resistant bacterial pathogens to human consumers. For this reason, it is advisable to use strict conditions in cheese processing to reduce the hazards that may be involved with its consumption
The diagnosis and management of low back pain in general practice
Get PDFAn evidence based discussion, illustrated with a made up case history, of a methodfor approaching patients with low back pain in general practice
Prevalence of meropenem susceptibility among Gram-negative pathogens isolated from intensive care units in Jordan
Get PDFMeropenem is a relatively new carbapenem in some Middle Eastcountries; our aim is to evaluate its susceptibility in gram-negative pathogens isolatedfrom ICU patients and to identify the prevalence of ICU bacterial isolates identifiedas pathogens based on CDC-NHSN definition for pathogens in the affected organs
Spread of CTX-M-15 Extended Spectrum β-lactamases Encoding Genes Among Enterobacteriaceae in the Middle Eastern Region
Get PDFThe CTX-M type enzymes have become the most prevalent extended spectrumβ-lactamases (ESBLs) worldwide. Among the CTX-M type enzymes, CTX-M-15 is themost widespread and has been reported from all continents. It has been recoveredfrom different Enterobacteriaceae and has been isolated from both community andhospital acquired infections. This review primarily highlights the prevalence of CTXM-15 in addition to other ESBLs in the Middle East. Detection of any type of ESBL isof importance in therapeutic treatment
General malaise in an elderly male patient
Get PDFPatients with general malaise or feeling non-specifically unwell is a common scenariofaced by all doctors. This case study reviews the made up case of an elderly malewith these symptoms presenting to his primary care practitioner and his subsequentmanagement in hospital. An evidence based clinical question and discussion of theethical and personal impact of the case is also presented
Treatment type of 212 cases of community acquired and nosocomial bacterial meningitis
Get PDFBacterial meningitis requires early treatment with aggressive use of potent antimicrobials,otherwise the outcome almost ends fatally
Editorial: Dear Readers of IAJAA
Get PDFWE are pleased to start publishing the first review and research papers in our first issueof IAJAA / November 2011. These papers were authored by Arab researchers who arewell known in their academic profession and as researchers in the field of antimicrobialagents and infectious disease
Frequency of antimicrobial resistance markers among Pseudomonas aeruginosa and Escherichia coli isolates from municipal sewage effluent water and patients in Jordan
Get PDFThe objective of this study was to compare the frequency of antimicrobial resistancemarkers of P. aeruginosa and E.coli isolates from effluent of sewage treatment plantsand clinical specimens over the same period in Jordan