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From Campus Gates to City Streets: Uber’s Place in the Ride-Hailing Industry
Get PDFUber is a technology company most famous for its ride-sharing service and its food-delivery service, UberEATS. Founded in 2009, the service operates by allowing riders to connect with available drivers as a type of on-demand taxi service, with UberEATS being formed in 2014 after Uber’s initial success, allowing drivers to deliver food from restaurants to customers. Uber’s convenience and simplicity has made them a very common method for quick trips, drop-offs, and quick food pickups.
The Fortune 500 company is immensely popular among Sacred Heart University’s student population, as the travel service allows students to explore farther-out parts of Fairfield, and UberEATS allows students to not have to worry about wasting time driving to get food during times of studying or working.
This presentation dives into the ride-hailing industry with a focus on Uber\u27s key perks and attributes that make it stand out among the rest
Nutrient Enrichment Alters Resource Allocation to Chemical Defenses in Invasive and Native Aquatic Plants
Get PDFEutrophication may alter plant allocation to chemical defenses, affecting interactions with herbivores and invasive species dynamics. We explored the effects of eutrophication on growth and chemical defenses in native and invasive aquatic plants, hypothesizing that plants would shift resources away from chemical defenses under nutrient enrichment and that grazers would consume more nutrient-enriched than unenriched tissue. We grew fragments of each species under ambient and enriched nutrient conditions in the lab for two weeks and measured their growth, phenolics, and condensed tannin content. Growth was similar across species and nutrient status. Both native and invasive plants relaxed their chemical defense production under nutrient enrichment, although the plants differed in their levels of phenolics and condensed tannins. Invasive Myriophyllum spicatum had higher phenolic levels and lower condensed tannin levels than native Ceratophyllum demersum under ambient nutrients. Nutrient enrichment reduced phenolic levels in M. spicatum and reduced condensed tannin levels in C. demersum. A no-choice feeding experiment with amphipods showed similar grazing on both plants, regardless of nutrient enrichment. These results show that both invasive M. spicatum and native C. demersum may relax their chemical defenses in eutrophic conditions, but effects on herbivory and invasion dynamics remain uncertain
Combination Resistance and Plyometric Training for Adolescent Baseball Athletes
Get PDFResistance training is important for developing youth baseball athletes and reducing the risks of injury. Most youth athletes can benefit from resistance training and baseball athletes especially can improve performance through a well-structured resistance and plyometric training program. A program combining traditional resistance training, plyometrics, speed and agility, and isometrics was implemented with our athlete over 11 months. 5-10-5 and 10-yard dash were measured using laser timing gates, the broad jump was measured using a tape measure on the floor and fastball velocity was measured using a radar gun. Testing was performed pre- and post-training program to measure improvement. Overall his performance increased significantly across all categories. The program effectively combines traditional strength training methods with plyometrics to provide the explosive power and stability a baseball player requires
Combined Screening of Different beta-lactamases Enzymes and CipP Protease from Staphylococcus aureus to identify Pharmaceutical Hits
Get PDFBacteria has evolved in much more rigorous conditions that today; they have developed mechanisms to survive. A need is for novel antibiotics is imperative. Beta-lactamases are enzymes produced by bacteria that provide multi-resistance to beta-lactam antibiotics. Beta-lactamase provides antibiotic resistance by changing the antibiotics\u27 structure. We are also investigating a protease ClpP that is in S. aureus maintaining protein homeostasis. Here, we describe the use of an iterative in silico and in vitro workflow for identifying novel beta-lactamase and protease ClpP inhibitors. Utilizing Molecular Operating Environment (MOE) as the software for our virtual screens. Our virtual screen model evaluates compounds that can be purchased for less than one- hundred dollars, therefore they can eventually be evaluated in vitro and in vivo. The Virtual Screen model that we employ uses multiple poses of the virtual compounds evaluating them via multiple criteria. Then an excel Pivot table is used to identify the duplicates with the logic being the more times a virtual compound appears with a good score it may be of interest to test in vitro. We are evaluating different beta-lactamases and ClpP proteases using different crystal structures then comparing the data from the different virtual screens. ADME studies are being performed on our top theoretical pharmaceutical hits. We have identified ractopamine as a μM inhibitor and a 50 μM inhibitor of a repurposed drug, in vitro against beta-lactamase. We think a novel method of identifying pharmaceutical hits has been revealed. The hope is to treat the patient with a Beta-lactamase inhibitor and then the normal penicillin like drug. ClpP protease is a new drug target, and we are hoping to discover novel inhibitors. Preliminary results appear encouraging, providing hope that a novel drug candidates will be identified and that our computational workflow will prove useful on other pharmaceutical targets
Effective Strategies to Prevent Central Line Associated Bloodstream Infections
Get PDFCLABSIs, or central line-associated bloodstream infections, have become a serious concern in the hospital setting. CLABSIs occur when bacteria enter the bloodstream through a central venous catheter, yet they are preventable with the proper interventions. The purpose of this project is to identify evidence-based interventions in the prevention of CLABSI to improve patient outcomes
Use of Alter G Treadmill for Returning From Lower Extremity Injury
Get PDFA fractured fifth metatarsal is a common weight-bearing injury that often requires progressive rehabilitation to restore gait and prevent re-injury. The AlterG treadmill enables reduced bodyweight walking and captures detailed gait metrics, supporting recovery by offloading pressure and promoting symmetrical movement. In this case, the non-injured ankle maintained strength with minor gains, while the injured ankle showed notable improvement, particularly in plantarflexion. Gait analysis revealed significant increases in plantar pressure symmetry and overall limb loading. Early asymmetry reflected protective strategies, while Week 4 data indicated restored confidence and function in the injured foot. AlterG treadmill use promoted improved gait mechanics, making it an effective tool for supporting recovery from lower extremity injuries
The Impact of Bilingualism on Post-stroke Aphasia Recovery and Language Outcomes
Get PDFThis literature review explores the impact of bilingualism on recovery outcomes and language proficiency in individuals with post-stroke aphasia. This review synthesizes findings from various studies assessing the rehabilitation trajectories of bilingual and monolingual patients. Key findings indicate that bilingual patients exhibit more favorable recovery outcomes, particularly when therapy is administered in their native language (L1), leading to enhanced naming accuracy and overall recovery rates compared to monolingual peers. While bilingual individuals generally recover better, cross-language generalization effects are limited, emphasizing the importance of targeted therapy in the patient\u27s primary mode of communication. Furthermore, younger bilinguals demonstrated significantly improved recovery metrics, while older individuals showed no significant divergence from monolingual recovery patterns. These insights not only contribute to understanding the cognitive and linguistics processes associated with bilingualism in aphasia but also suggest critical implications for clinical rehabilitation practices aimed at enhancing patient care and treatment efficacy
Project Luna
Get PDFIn alignment with NASA’s Exploration Systems and Development Mission Directorate, this project aims to address exploration challenges related to energy consumption, mobility, and the speed of mission results for the NASA Mars rover. Current rovers face limitations due to inefficient power consumption, which constrains mission capabilities and operational duration. This research seeks to develop and implement advanced solar panel technology to optimize energy harnessing, enabling rovers to operate independently for extended periods and support long-duration missions.
The project’s initial phase focuses on solar panel research, with an emphasis on designing, building, and testing a small-scale solar-powered system to evaluate its efficiency and broader capabilities. This system will serve as the project’s minimum viable product (MVP), providing a foundation for further exploration into integrating advanced solar technology with rover power systems.
In the broader scope, the findings from this research will be applied to a small-scale rover prototype, assessing the compatibility of the solar-powered system with a power train. This iterative testing will culminate in the implementation of the system on a spherical rover design, aiming to enhance mobility, energy efficiency, and mission adaptability in extraterrestrial environments. By addressing these critical energy challenges, this project contributes to the advancement of exploration technologies and supports NASA’s mission objectives