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Keeping things spicy: Effects of Capsaicin Analogs on Proliferation and Differentiation of Skeletal Myoblasts
No full textWittgenstein, Empiricism, and Pragmatism: Examining the Evolution of Wittgensteinian Solipsism
Get PDFIn this paper I will argue for an interpretation of Ludwig Wittgenstein’s Tractatus Logico-Philosophicus as a work of empiricism, as well as an argument for his Philosophical Investigations as a work of pragmatism, and how these two interpretations apply to Wittgenstein’s formulation of solipsism. Specifically, I will show how an empiricist understanding of the Tractatus leads Wittgenstein to his formulation of solipsism, which is untenable because it is unsayable. Similarly, I will show how a pragmatic understanding of the Investigations gives Wittgenstein a “way out” of his Tractarian solipsism, specifically with his formation of the private language argument as a direct response to his earlier views on solipsism
The Usability and Privacy of Cryptocurrency
Get PDFOver the last few years, cryptocurrency has gained mainstream attention because of its decentralized nature and elements of privacy. However, Cryptocurrency may not be as private as users seem and still has usability and privacy concerns. The purpose of this paper is to compare the usability and privacy characteristics of popular cryptocurrencies, like Bitcoin, Ethereum, and Litecoin. The elements that illustrate the usability and privacy of these cryptocurrencies include ease of use, transaction speed, transaction cost, and privacy features. While Bitcoin offers some levels of privacy, its transaction speed and cost are relatively high. Litecoin, on the other hand, offers quicker and lower transactions but lacks advanced privacy features. Ethereum tries to meet in the middle between these two by offering reasonable transaction speed and cost, along with advanced privacy features. Overall, I believe that cryptocurrency can be a secure technology to use but it depends on the knowledge and measures taken by users to protect their privacy.
Keywords: Cryptocurrencies, Bitcoin, Ethereum, Litecoin, Usability, Privacy
Exploring the Relationship Between Political Regime Type and Cancer Mortality
Get PDFThis paper aims to establish a relationship between political regime type and public health outcomes. Looking specifically at cancer mortality, I employed a mixed-methods research approach to examine a potential relationship. I hypothesized that there would be a strong relationship between cancer mortality rates and regime types showing that democratic regimes have better outcomes due to democratic countries prioritizing public health more than autocracies. Initially, the paper provides an overview of the global cancer burden and outlines the political regime types in Canada and Russia, juxtaposed with their respective freedom scores. I then conducted statistical analysis, including regression analysis, to determine the strength of the relationship between cancer mortality and regime type. This analysis included 20 countries, including Canada and Russia, and used Freedom House Global Freedom Scores to represent regime type. While statistical analysis did not yield statistically significant results, a comprehensive case study approach was undertaken to elucidate other factors influencing cancer mortality rates. The countries of Canada and Russia were examined in this case study as representatives of democracy and autocracy, respectively. Factors such as the structure and performance of healthcare systems, GDP allocation towards healthcare, prevalence of preventive healthcare measures, and health literacy levels are analyzed to offer deeper insights. Ultimately, this research aims to foster deeper understanding and inform targeted interventions aimed at improving population health and well-being, contributing to the ongoing discourse on the intersection of political governance and public health outcomes
Reappraisal vs. Rumination: Emotion Regulation Shapes Reactions to Prejudice Confrontation
Get PDFWhen called out for prejudiced behavior, people exhibit varied emotional and behavioral reactions. Emotions like guilt or empathy can drive adaptive behavioral responses like self-correction, while anger or resentment can provoke maladaptive responses, such as hostility and dismissiveness. This research explored how naturally occurring emotion regulation strategies, like cognitive reappraisal and rumination, influence these emotional and behavioral reactions. We asked 250 U.S. adults to recall a time when they had acted offensively and were consequently confronted for it. We then recorded their emotion regulation strategies and resultant responses. Our findings revealed that reappraisal led to self-correction by intensifying guilt and empathy while reducing anger and pride. However, rumination led to mixed responses: it increased guilt and empathy, as well as anger and distress, triggering a mixed bag of self-correction, hostility, and defensive explanations. These insights suggest potential pathways to guide individuals’ emotion regulation toward more productive responses when confronted about prejudice
Interaquatic Assault
No full textWe held an alpha test for our senior project in Game Design and Development. In the alpha test, the entire class played the game and answered 7 questions to help us make improvements to the game. From the survey results we were able to make improvements for our upcoming beta test to let anyone who wanted to play our game Interaquatic Assault
Knowledge Translation Task Force for Core Measures Clinical Practice Guideline: A Short Report on the Process and Utilization
Get PDFBackground
As part of the 2018 Clinical Practice Guideline (CPG): A Core Set of Outcome Measures for Adults with Neurologic Conditions Undergoing Rehabilitation, a Knowledge Translation (KT) Task Force was convened. The purpose of this short report was to (1) demonstrate the potential impact of a CPG KT Task Force through a practical example of efforts to implement a CPG into neurologic physical therapy practice and (2) describe the process to convene a KT Task Force and develop products (KT Toolkit) to facilitate implementation of the CPG. Methods
To describe the process used by the KT Task Force to develop and review a KT Toolkit for implementation of the CPG. Results
Utilizing the Knowledge-To-Action Cycle framework, eight tools were developed as part of the KT Toolkit and are available with open access to the public. Findings indicate that the Core Outcome Measures Homepage, which houses the KT Toolkit, has had greater than 70,000 views since its publication. Conclusions
This short report serves as an example of the efforts made to implement a CPG into physical therapy practice. The processes to facilitate KT and the tools developed can inform future implementation efforts and underscore the importance of having a KT Task Force to implement a CPG. Moving forward, KT Task Forces should be convened to implement new or revised guidelines
Clinical Inquiry and Problem Identification
No full textThis is the second article in a new series designed to provide readers with insight into educating nurses about evidence-based decision-making. It builds on AJN\u27s award-winning previous series—Evidence-Based Practice, Step by Step and EBP 2.0: Implementing and Sustaining Change (to access both series, go to https://links.lww.com/AJN/A133). This follow-up series will address how to teach and facilitate learning about the evidence-based practice (EBP) and quality improvement (QI) processes and how they impact health care quality. This series is relevant for all nurses interested in EBP and QI, especially DNP faculty and students. The brief case scenario included in each article describes one DNP student\u27s journey
Health Behaviors Predicting Risk of Obesity in US Adults: What Does a Healthy Lifestyle Look Like?
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The purpose of this study was to examine the association between lifestyle factors and body weight in a nationally representative sample of US adults and to evaluate the association between a novel “Healthy Habits Composite Score (HHCS)” and risk of obesity. Methods
This cross-sectional study included data from 4870 adults who participated in the 2017–2018 National Health and Nutrition Examination Survey (NHANES). The HHCS was developed based on 4 factors: diet, physical activity, sedentary time, and sleep, all of which were measured during the NHANES. A “healthy lifestyle” was defined as meeting ≥3 of the 4 established criteria. Data analysis was conducted using SAS 9.4 and procedures to account for the complex survey design. All models were adjusted for age, sex, race, household income, and education. Results
Adults with obesity had significantly lower dietary quality (48.8 ± 0.6 vs. 53.2 ± 0.9) and reported significantly more sedentary time (∼1 h more; 356.3 ± 7.0 vs. 301.4 ± 8.3 min) than lean adults, both p \u3c 0.001. Achieving a healthy lifestyle based on the HHCS was associated with nearly double the odds of having a healthy body weight (OR 1.9, p \u3c 0.001). Conclusions
Following a lifestyle focused on healthy habits (diet quality, physical activity, limited sedentary time, and sleep) was strongly associated with a decreased risk of obesity: an individual who achieved three or more healthy habits had nearly twice the odds of having a healthy body weight. Therefore, comprehensive interventions that address and promote a wide range of healthy habits may be most effective for lowering obesity risk