e-Publikasi Ilmiah Unwahas (Universitas Wahid Hasyim)
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RESPON KOMPONEN PRODUKSI TANAMAN TOMAT YANG DIBERI PERLAKUAN PUPUK ORGANIK PLUS
Get PDFProduksi tanaman tomat dipengaruhi oleh faktor lingkungan salah satunya kesuburan tanah. Tanah dengan kondisi yang subur dapat menghasilkan produksi yang optimal begitu juga sebaliknya tanah dengan kesuburan tanah rendah dapat menghasilkan produksi yang rendah pula. Penelitian ini bertujuan untuk mengkaji respon komponen produksi tanaman tomat yang diberi perlakuan pupuk organik plus. Penelitian ini dilaksanakan di Laboratorium Agroteknologi dan Screen House Program Studi Agroteknologi pada bulan Agustus-November 2023.  Rancangan yang digunakan dalam penelitian adalah rancangan acak kelompok (RAK) dengan perlakuan pupuk organik plus. Perlakuan terdiri dari 6 taraf yakni tanpa pupuk organik plus (P0), pupuk organik plus 3 t.ha-1 (P1), 6 t.ha-1 (P2), 9 t.ha-1 (P3), 12 t.ha-1 (P4),  dan 15 t.ha-1 (P5). Variabel yang diamati adalah umur panen, jumlah buah, berat buah, diameter buah, dan produktivitas.  Data pengamatan yang diperoleh dari setiap variabel dianalisis ragam dan hasil analisis yang menunjukkan pengaruh nyata atau sangat nyata dilanjutkan dengan Uji Jarak Berganda Duncan (UJBD) pada taraf α0.05. Hasil penelitian menunjukkan bahwa perlakuan pupuk organik plus dapat meningkatkan komponen produksi tanaman tomat yakni umur panen, jumlah buah, berat buah, diameter buah, dan produktivitas. Perlakuan terbaik diperoleh pada pupuk organik plus dosis 15 t.ha dibandingkan dengan perlakuan lainnya terutama tanpa perlakuan pupuk organik plus (kontrol). Kata kunci: Produksi, tomat, pupuk organik plus, respo
STUDI KASUS IMPLEMENTASI PENGELOLAAN OPT DALAM RANGKA KEBERLANJUTAN EKOSISTEM PERTANIAN SERTA KAITANNYA TERHADAP PERAN PENYULUH DAN PRODUKTIVITAS PADI SAWAH DI KABUPATEN ASAHAN
Get PDFPlant Pest Organisms play an important role in plant growth and productivity. Therefore, the role of extension workers is very important in encouraging farmers to adopt sustainable management of plant pest organisms. The analytical method used was a descriptive research method with a case study approach in three rice production center sub-districts, Asahan Regency with a total sample of 368 farmers. The research results found that farmers have carried out sustainable management of Plant Pest Organisms and achieved a balance effectiveness in controlling pests and environment
Strategi Pengembangan Manajemen Agribisnis Jagung di Desa Talumelito Kecamatan Telaga Biru
No full textStrategi pengembangan manajemen agribisnis jagung adalah rencana atau langkah-langkah yang dirancang untuk meningkatkan efesiensi, produktivitas, dan distribusi jagung. Penelitian ini bertujuan untuk mengetahui strategi pengembangan agribisnis jagung di Desa Talumelito Kecamatan Telaga Biru. Penelitian ini dilakukan pada bulan Agustus - Oktober 2023. Jenis penelitian ini adalah penelitian survei. Pengambilan sampel menggunakan Simple random Sampling dengan jumlah responden sebanyak 37 orang. Metode yang digunakan dalam pengambilan data adalah observasi, wawancara, kuesioner, dan dokumentasi. Metode analisis yang digunakan adalah analisis SWOT. Hasil penelitian ini menunjukkan bahwa strategi pengembangan agribisnis jagung di Desa Talumelito Kecamatan Telaga Biru mendukung strategi agresif atau strategi S-O (Strengths-Opportuninites) yang ditunjukkan pada kekuatan dan peluang yang dimiliki. Dimana petani memaksimalkan kerjasama antar petani dengan adanya dukungan bantuan dari pemerintah, kemudian memanfaatkan pengalaman petani untuk meningkatkan efektivitas dan efisiensi usahatani dalam penggunaan teknologi modern, serta mengoptimalkan sarana dan prasarana usahatani yang mudah diakses petani dalam pemanfaatan potensi lahan pertanian yang baik.Kata Kunci : Agribisnis, Jagung, SWO
Analisis Drugs Related Problems pada Pasien Kanker Payudara di Rumah Sakit Umum Daerah KRMT Wongsonegoro Semarang Tahun 2022
Get PDFDrugs Related Problems (DRPs) are problems related to patient treatment that can affect the effectiveness and safety of therapy. Breast cancer patients who receive chemotherapy usually consists of a combination of several drugs. Administration of a combination of chemotherapy drugs can cause DRPs. This study aims to determine the actual and potential incidence of DRPs and their causes in breast cancer patients at the KRMT Wongsonegoro Regional General Hospital, Semarang in 2022. This research was conducted observationally with a cross-sectional research design and retrospective data collection by observing medical record data of breast cancer patients. There were 30 samples that met the inclusion and exclusion criteria. The classification of DRPs refers to the Regulation of the Minister of Health of the Republic of Indonesia Number 34 of 2021 concerning Standards of Pharmaceutical Services in Clinics. DRPs were analyzed using the National Guidelines for Medical Services for Breast Cancer Management in 2018. Analysis of potential drug interactions used medscape.com. Data analysis was carried out descriptively. The results showed that the most frequently used chemotherapy regimen was cyclophosphamide + doxorubicin + fluorouracil (76.67%). All patient samples experienced actual and potential DRPs with the cause being indication without medication (46.67%), medication without indication (0%), too high a dose (90%), too low a dose (100%), side effects undesired (100%), potential drug interactions (100%) and duration of treatment (53.2%). The prevalence of DRPs in our setting was high so that it could affect therapy outcomes of patient. Therefore, it is hoped that there will be an evaluation to reduce the prevalence of DRPs, by optimizing clinical pharmacy service practices such as reviewing prescriptions, monitoring effectiveness therapy and adverse drug reaction also conducting interprofessional collaboration
Asthma Control and Quality of Life of Asthma Patients At St General Hospital
Get PDFAsthma is a chronic condition characterized by chronic airway inflammation that causes various respiratory symptoms that can severely impact a patient's daily life. Suboptimal control of asthma is associated with increased costs of care and treatment and decreased quality of life (QoL). This study aims to examine asthma control status and its relationship with the QoL of asthma patients at ST. General Hospital. This cross-sectional study involved 50 asthmatics aged 18-65 who attended ST. General Hospital. Two questionnaires were used: an asthma control test (ACT) and an adult asthma quality-of-life questionnaire (Mini-AQLQ). By using SPSS, the Spearman Rank test was employed to identify associations with a 95% confidence level. Of the 50 respondents studied, asthma status was categorized as partially controlled (50%), totally controlled (14%), and uncontrolled (36%). A significantly worse QoL was observed in respondents with uncontrolled asthma, whereas a good QoL (minimal or no impairment) was observed in partially controlled respondents (p = <0.001). There was a relationship between asthma control and the respondent's QoL (rho = 0.832). Appropriate treatment will increase asthma control and improve the QoL of patients treated at ST. General Hospital. Further research is needed to evaluate risk factors, psychological effects, and behavioral screening in poorly controlled asthma patients
Pengembangan Sistem Dispersi Padat Ezetimibe dengan Matriks PEG 8000 menggunakan Metode Peleburan
Get PDFEzetimibe termasuk pada Biopharmaceutics Classification Sistem (BCS) kelas II yang memiliki kelarutan yang rendah, sehingga laju disolusi dan bioavailabilitas oralnya rendah. Suatu sistem disperse padat dapat meningkatkan luas permukaan obat dan kontak antara obat dan media disolusi, sehingga laju disolusi ezetimibe akan meningkat. PEG 8000 telah banyak digunakan sebagai suatu pembawa hidrofilik dan laktosa monohidrat serta avicel PH 101 sebagai adsorben.           Penelitian ini bertujuan untuk menimgkatkan laju disolusi dari obat ezetimibe yang tidak larut air dengan membentuk sistem dispersi padat ezetimibe_PEG 8000 dengan rasio 1:1; 1:2; dan 1:3. Sistem dispersi padat dibuat dengan metode peleburan. Evaluasi laju disolusi, difraksi X-ray (XRD), dan analisis  pada sistem dispersi padat dengan rasio 1:1; 1:2; 1:3, dan ezetimibe murni dilakukan.           Hasil dari evaluasi tersebut menunjukkan sistem dispersi padat meningkatkan laju disolusi dari ezetimibe. Selain itu, karakterisasi DTA menunjukkan hilangnya puncak endotermik dari ezetimibe pada dispersi padat dan hasil karakterisasi sinar-X menunjukkan penurunan intensitas relatif dari puncak ezetimibe yang memperlihatkan adanya perubahan bentuk kristal menjadi amorf. Kesimpulan dari penelitian ini adalah sistem dispersi padat ezetimibe-PEG 8000 dapat meningkatkan laju disolusi  dan karakteristik fisik dari ezetimibe.Â
A Literature Review On the Formulation, Characterization, and Stability of Cinnamomum burmannii Emulgel Extract as an Antioxidant and Sunscreen
Get PDFEmulgel is a pharmaceutical formulation that integrates the characteristics of both emulsions and gels, resulting in a semisolid product. The utilization of emulgel formulations has been shown to enhance the efficacy of drug delivery by facilitating deeper skin penetration and subsequently augmenting its pharmacological activity. The antioxidant and sunscreen properties of cinnamon bark extract make it suitable for incorporation into an emulgel formulation. Variations in the concentration of extracts and gelling agents can have an impact on the physical properties, stability, and pharmacological efficacy of the emulgel. The objective of this review is to ascertain the optimal concentrations of extracts and gelling agents in emulgel formulations for enhanced efficacy. The employed methodology entails conducting a comprehensive review of scholarly articles pertaining to emulgel formulations containing cinnamon bark extract. These formulations encompass a range of concentrations of both the extract itself and gelling agents, while also possessing antioxidant and sunscreen properties. The formulation that is recommended is one that satisfies the criteria pertaining to its physical attributes, stability, and pharmacological efficacy. The emulgel formulation that best meets the specified criteria consists of a 1% concentration of cinnamon bark extract in combination with the gelling agent Viscolam MAC 5%
Potensi Senyawa Salisilanilida Dari Minyak Gandapura Sebagai Antiinflamasi dan Analgetik Secara In Vivo
Get PDFAdministration of non-steroidal anti-inflammatory drugs (NSAIDs) is the first therapeutic choice for the treatment of pain and inflammation. Several existing amide derivatives show their properties as anti-inflammatory, antidegenerative, anticancer, antimicrobial and analgesic, one of which is salicylanilide. The precursor for salicylanilide synthesis is carboxylic acid, using natural methyl salicylate from gondopuro oil and amines sonochemically with the help of Decyclocarbodiimide (DCC) coupling reagent. The research aims to carry out the synthesis of amide derivatives using DCC coupling reagent with the sonochemical method in 7 hours. Identification of synthetic compounds by spectrum elucidation using infrared spectrophotometry (FTIR-ATR), GC-MS and in-vivo anti-inflammatory and analgesic activity tests. In this study, the mixture was sonicated for 7 hours at a temperature of ±0oC, then left in the refrigerator overnight, evaporated at a temperature of 65oC. The precipitate formed was filtered using Buchner, washed using cold distilled water and washed again using methanol. The crystals obtained were then dried in an oven at 40ºC until dry, then the % yield of the synthesized compound was determined. Tests include organoleptic tests, melting point, solubility, FTIR, GC-MS In vivo anti-inflammatory and analgesic activity tests. The research results showed that salicylanilide compounds could be synthesized in 7 hours with a % yield of 27.55%. The resulting synthesis can melt from a temperature of 218-222°C and can dissolve in methanol, ethanol, chloroform and ether but does not dissolve in distilled water. FTIR testing on salicylanilide compounds showed the presence of phenolic -OH, aromatic C-H, C=O amide and aromatic C=C groups. The synthesized compound produced an abundance of 2.43%. The highest percentage of anti-inflammatory power was at dose 3 synthesis (7.56 mg/ 200 grams of rat body weight) at 44.46% and the highest analgesic effect was at dose 4 synthesis (10.08 mg/ 200 grams Rat BW
Implementation Of M-Learning to Improve Learning Effectiveness In PAI Evaluation System Courses
Get PDFThe digital era greatly influences learning activities and facilitates access to learning materials anywhere and anytime. Flexibility of learning, high interactivity, personalization of learning are the basic considerations of IT utilization. The purpose of this research is to develop an M-learning-based lecture room application in PAI evaluation courses. This study is a research and development (R & D) study with the ADDIE model. The subjects of this study were 5th semester students of PAI Study Program as many as 132 people. Sampling using saturated sample technique. Data collection used observation, interview and questionnaire distribution. Product validity is assessed by experts and students as a feasibility test using independent sample t test analysis. Assessment by expert judgment shows that the value is very good, namely an average of 4.67 by media experts. The results of the study with independent sample t-test showed a significance value of 0.00 probability with a significance of 0.05, which means that there is a significant difference between classes that use discussions and classes that are accompanied by the lecture hall application. This product has a very practical assessment by students as a reference for independent learning with an average score of 3.78. This M-Learning contributes more effectively and efficiently if done outside the classroom as a companion to independent learning
The Utilization of Green Mussel Shell Waste for The Production of Hydroxyapatite Using Sol-Gel Method
Get PDFHydroxyapatite is a type of ceramic biomaterial made up of calcium and phosphate, with a chemical formula of Ca10(PO4)6(OH)2. The Calcium used in this research was obtained from Green Mussel Shell Waste Precipitated Calcium Carbonate. The research was conducted using the sol-gel method to determine the optimal conditions for hydroxyapatite synthesis with the variable of H3PO4 solution at 0.1 M, 0.5 M, and 1 M. The result at the concentration of H3PO4 on 1 M turns out the optimal condition. The hydroxyapatite synthesis using the sol-gel method with a concentration of 1 M pH 12 phosphoric acid was successfully conducted and known as the optimal condition in this research. From the synthesis results, the characterization of hydroxyapatite synthesis shows there was a P-O bond at 995.27 cm-1 and an OH- bond at 3068.75 cm-1. The ratio of Ca/P calculated is 1.68 which is close to the standard ratio Ca/P of hydroxyapatite