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H ∞ dynamic output-feedback control for a class of linear neutral delay systems
No full texta b s t r a c t In this paper, the problem of output feedback stabilization is considered for a class of switched delay systems under asynchronous switching. When the switching signal of the switched controller involves delay, by constructing a novel Lyapunov functional which is allowed to increase during the running time of active subsystems with the mismatched controller, sufficient conditions for exponential stability are developed for a class of switching signals based on the average dwell time method. Moreover the stabilizing output feedback controllers are designed. Finally, an example is given to demonstrate the feasibility and effectiveness of the proposed design techniques
IMPROVEMENT OF MERINO REPRODUCTIVE PERFORMANCE THROUGH BLOODLINE SUBSTITUTION AND CROSSING
No full textSUMMARY The size and relative influence of direct and maternal components of bloodline effects and average heterosis on fertility, litter size, lamb survival and net reproduction rate of Merinos were examined to assess the opportunity for improvement of Merino reproductive performance through bloodline substitution and crossing. Data on more than 8500 ewes from a Merino bloodline crossing experiment were analysed. Direct bloodline effects influenced significantly litter size only, whereas maternal bloodline significantly affected litter size, lamb survival and net reproduction rate. Direct heterosis was a significant influence on fertility and net reproduction rate, with crossbred matings being 4% more fertile and having 7% more lambs per ewe mated. Significant maternal heterosis for litter size, lamb survival and net reproduction rate indicated that crossbred dams had larger litters (3%) and higher lamb survival (7%) and weaned more lambs per ewe mated (8%). Reproductive performance of Merino flocks can be improved by both between bloodline selection and structured crossing systems
Family Victimisation and Plight of Elderly Women: A Representative Study in Odisha State of India
No full textAbstrac
EFFECT OF MAGNEVIST CONJUGATED DENDRIMER ON Bax/Bcl2 GENE EXPRESSION LEVELS IN MCF-7 CANCER CELLS
No full textKEYWORDS Magnevist conjugated dendrimer Real-time PCR MCF-7 Apoptosis Corona protein ABSTRACT In recent years, investigating pharmacogenetics and effects of corona protein nanomaterial in biological applications has been seriously considered for the treatment of human diseases. In this study, the mechanism of apoptosis induced by Magnevist conjugated dendrimer was investigated to compare Magnevist as a contrasting agent on MCF-7 cells. Cytotoxicity effects of new Magnevist conjugated dendrimer was evaluated by using MTT assay. Also, In order to demonstrate the effect of drugs on the apoptosis, a quantitative method real-time PCR was used. The interaction of plasma proteins was investigated by Magnevist conjugated dendrimer compared with Magnevist using SDS-PAGE technique to determine the fate of nanoparticles. Result of study revealed that it quite significantly affects Bax and increasing apoptosis. Its effect on Bcl2 is more than net gadopentetic acid and almost equivalent to the effect of dendrimer alone. In fact, a significant increase was observed in Bax compared to the control group, and no significant effect was observed on BCL2 gene. Also, corona protein was investigated and the protein with weight less than 70 kDa was observed around a nanoparticle that seems albumin protein with a molecular weight of 67 kDa. Conducted study revealed the acceptable therapeutic effect of Magnevist conjugated dendrimer and it was comparable with in vitro Magnevist model of breast cancer. Therefore, the use of the denderimer can be effective on increasing expression of some proapoptoticgenes and provided a new perspective in clinical diagnostic
ELASTIC ELECTRON HELIUM SCATTERING SPECTRA ASSISTED BY A CO 2 LASER FIELD
No full textAbstract We have studied theoretically the electron spectra in the elastic scattering of a fast electrons (E i = 9.5 eV) by helium atoms in the presence of a CO 2 monochromatic laser field and in the presence of a CO 2 bichromatic laser field. The former is linearly polarized, and has moderate intensity (I=10 8 Wcm -2 ) with photon energy eV 117 . 0 = ω h . The latter has the same polarization and has two components of frequencies ω and 2ω which are out of phase by an arbitrary angle ϕ. Our numerical results (in the Born approximation) show that the scattered signal is sensitive to the collision geometry. Otherwise it is easily controllable by the phase variations, especially at the quadrature of the phase (ϕ = π/2) the signal in the presence of the CO 2 monochromatic laser can be reproduced by a CO 2 bichromatic laser field with less intensity what would be a great advantage in laser spectroscopy
Formalization of the prime number theorem and Dirichlet's theorem
No full textWe present the formalization of Dirichlet's theorem on the infinitude of primes in arithmetic progressions, and Selberg's elementary proof of the prime number theorem, which asserts that the number π(x) of primes less than x is asymptotic to x/ log x, within the proof system Metamath
Clinical Study Effects of Telmisartan with Hydrochlorothiazide versus Valsartan with Hydrochlorothiazide in Patients with Moderate-to-Severe Hypertension
No full textCombination therapy is recommended for patients with blood pressure (BP) significantly above goal by recent consensus guidelines around the globe. The use of angiotensin II receptor blockers (ARBs) alone or in combination with a thiazide diuretic is a preferred treatment strategy due to both efficacy and safety considerations. However, there are few data known about the benefits of ARB-diuretic combination therapy in patients with moderate-to-severe hypertension. We performed a subanalysis from two large clinical trials that compared the antihypertensive effects of telmisartan 80 mg versus valsartan 160 mg, both combined with hydrochlorothiazide (HCTZ) 25 mg in a subpopulation of 725 patients with moderate-to-severe hypertension (systolic BP SBP ≥ 160 mm Hg). Treatment with telmisartan-HCTZ induced significantly greater reductions in BP (−31.1/−18.3 mm Hg) than valsartan-HCTZ (−28.4/−16.3 mm Hg; SBP P = 0.0265, diastolic BP P = 0.0041). More patients receiving the telmisartan combination achieved a BP goal < 140/90 mm Hg than those receiving valsartan-HCTZ. There were similar safety and tolerability data for the two active treatment groups. These findings support the use of longer-acting ARBs combined with higher doses of thiazide diuretic to improve BP control in patients with moderate-to-severe hypertension
Similar ities between the L-H tr ansition in fusion plasma and the appear ance of a self-or ganized str uctur e in low-temper atur e plasma
No full textThe achievement of a high density and high temperature plasma for a long confinement time constitutes the main goal of controlled thermonuclear fusion research. By increasing the heating power, first a degradation of energy and particle confinement is obtained (L-mode). Above a certain threshold value of this power, a regime of improved energy and particle confinement (H-mode) is attained. The H-mode is characterized by sharp gradients of the density and the temperature in the plasma edge region, indicating the formation of a transport barrier In this work we would like to emphasize a certain striking similarity between the L-H transition in fusion plasmas and the appearance of a complex structure in low-temperature plasmas. Under particular experimental conditions, a complex space charge configuration (CSCC) can appear in form of an ion-rich plasma region confined by a plasma double layer Upon its appearance, a well-localized radial electric field develops in the edge region due to the double layer, which works as a radial transport engine Exper imental r esults The experiments were performed in the target chamber of the DP (double plasma) machine of the University of Innsbruck, schematically presented i