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Hydrodynamic Modeling of Targeted Magnetic-Particle Delivery in a Blood Vessel
No full textSince the flow of a magnetic fluid could easily be influenced by an external magnetic field, its hydrodynamic modeling promises to be useful for magnetically controllable delivery systems. It is desirable to understand the flow fields and characteristics before targeted magnetic particles arrive at their destination. In this study, we perform an analysis for the effects of particles and a magnetic field on biomedical magnetic fluid flow to study the targeted magnetic-particle delivery in a blood vessel. The fully developed solutions of velocity, flow rate, and flow drag are derived analytically and presented for blood with magnetite nanoparticles at body temperature. Results reveal that in the presence of magnetic nanoparticles, a minimum magnetic field gradient (yield gradient) is required to initiate the delivery. A magnetic driving force leads to the increase in velocity and has enhancing effects on flow rate and flow drag. Such a magnetic driving effect can be magnified by increasing the particle volume fraction
Antishadowing Effect on Charmonium Production at a Fixed-Target Experiment Using LHC Beams
No full textWe investigate charmonium production in Pb + Pb collisions at LHC beam energy lab = 2.76 TeV at fixed-target experiment (√ NN = 72 GeV). In the frame of a transport approach including cold and hot nuclear matter effects on charmonium evolution, we focus on the antishadowing effect on the nuclear modification factors AA and AA for the / yield and transverse momentum. The yield is more suppressed at less forward rapidity ( lab ≃ 2) than that at very forward rapidity ( lab ≃ 4) due to the shadowing and antishadowing in different rapidity bins
Treatment in Psychiatry Disruptive Mood Dysregulation Disorder: A New Diagnostic Approach to Chronic Irritability in Youth
No full textInjection molding of zirconia (Y-TZP) ceramics
No full textCeramics Abstract h!/eetion mouhting of ceramics (CIM) is considered as a promising shaping technique. An investigation was started to test whether it+]ection mouhting o[ t'ttrium oxide stabili, ed tetragonal ,ireonia polycrystals (Y-TZP) can result in products wit
Critical Constructs of Digital Library Interaction
No full textAbstract The perception of fundamental dimensions of digital library (DL) interaction requires the deep exploration of interactive events. Interaction in DLs depends to a great degree on the content they provide. The present study validates a theoretical framework for the usefulness-usability linking, based on the areas of HCI and Information Behaviour. An online questionnaire survey was employed to elicit DL users' opinions on the usefulness and usability of an Open Access system. Results demonstrate the most crucial system and content evaluation attributes that can affect satisfaction on the usefulness and usability of DLs
Correlation of liquid viscosity with molecular structure for organic compounds using different variable selection methods
No full textAbstract Improved models for predicting viscosities at 20 C were generated using three different methods for descriptor selection. Data set of 361 diverse organic molecules and their experimental viscosities were used for developing the models. Molecular properties are encoded by 822 initial descriptors computed by the CODESSA program. CODESSA, GFA and CROMRsel methods are capable of selecting good and facile viscosity models having only five descriptors. These methods are automated procedures for generation of simple multiregression (MR) models. All three methods produce excellent linear models, but the models obtained by the CROMRsel method are somewhat better. In addition, using the CROMRsel suite of programs a very good nonlinear MR model having five descriptors (two linear and three cross-product descriptors, R 2 = 0.908, S = 0.175) was obtained. Nonlinear models generated in this study show that the classical MR based methods can be efficiently used to obtain simple and very good nonlinear MR models. The best five-descriptor models selected in this study usually contain one geometrical (gravitational index) and one topological descriptor (Randi index of order 0), and three electrostatic descriptors which reflect the bonding properties of molecules, i.e. their capabilities to create (mainly) hydrogen bonds. Because of that, hydrogen-donors and hydrogen-acceptors surface areas, charges, total molecular surface areas, and maximum net atomic charges and state energies for oxygen atoms appear to be key factors for modeling the viscosity of organic molecules
Accepted for Photonic Network Communications
Get PDFAbstract-When deploying Grid infrastructure, the problem of dimensioning arises: how many servers to provide, where to place them, and which network to install for interconnecting server sites and users generating Grid jobs? In contrast to classical optical network design problems, it is typical of optical Grids that the destination of traffic (jobs) is not known beforehand. This leads to so-called anycast routing of jobs. For network dimensioning, this implies the absence of a clearly defined (source,destination)-based traffic matrix, since only the origin of Grid jobs (and their data) is known, but not their destination. The latter depends not only on the state of Grid resources, including network, storage, and computational resources, but also the Grid scheduling algorithm used. We present a phased solution approach to dimension all these resources, and use it to evaluate various scheduling algorithms in two European network case studies. Results show that the Grid scheduling algorithm has a substantial impact on the required network capacity. This capacity can be minimized by appropriately choosing a (reasonably small) number of server site locations: an optimal balance can be found, in between the single server site case requiring a lot of network traffic to this single location, and an overly fragmented distribution of server capacity over too many sites without much statistical multiplexing opportunities, and hence a relatively large probability of not finding free servers at nearby sites
No full textABSTRACT The mouse and human genomes contain 14 highly conserved SLC39 genes. Viewed from an evolutionary perspective, SLC39A14 and SLC39A8 are the most closely related, each having three noncoding exons 1. However, SLC39A14 has two exons 4, giving rise to Zrt-and Irt-related protein (ZIP)ZIP14A and ZIP14B alternatively spliced products. C57BL/6J mouse ZIP14A expression is highest in liver, duodenum, kidney, and testis; ZIP14B expression is highest in liver, duodenum, brain, and testis; and ZIP8 is highest in lung, testis, and kidney. We studied ZIP14 stably retroviral-infected mouse fetal fibroblast cultures and transiently transfected Madin-Darby canine kidney (MDCK) polarized epithelial cells. Our findings include: 1) ZIP14-mediated cadmium uptake is proportional to cell toxicity, bu