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Women Have Higher Protein Content of b-Oxidation Enzymes in Skeletal Muscle than Men
Abstract It is well recognized that compared with men, women have better ultra-endurance capacity, oxidize more fat during endurance exercise, and are more resistant to fat oxidation defects i.e. diet-induced insulin resistance. Several groups have shown that the mRNA and protein transcribed and translated from genes related to transport of fatty acids into the muscle are greater in women than men; however, the mechanism(s) for the observed sex differences in fat oxidation remains to be determined. Muscle biopsies from the vastus lateralis were obtained from moderately active men (N = 12) and women (N = 11) at rest to examine mRNA and protein content of genes involved in lipid oxidation. Our results show that women have significantly higher protein content for tri-functional protein alpha (TFPa), very long chain acyl-CoA dehydrogenase (VLCAD), and medium chain acyl-CoA dehydrogenase (MCAD) (P,0.05). There was no significant sex difference in the expression of short-chain hydroxyacyl-CoA dehydrogenase (SCHAD), or peroxisome proliferator activated receptor alpha (PPARa), or PPARc, genes potentially involved in the transcriptional regulation of lipid metabolism. In conclusion, women have more protein content of the major enzymes involved in long and medium chain fatty acid oxidation which could account for the observed differences in fat oxidation during exercise
Sistema de seguimiento y análisis de la calidad del agua para consumo humano mediante el estudio de la respuesta comportamental en peces expuestos a sustancias tóxicas* La obtención de variables relacionadas con cambios comportamentales en los estudios sobre los efectos subletales de sustancias tóxicas en animales, constituyen una herramienta fundamental para la evaluación del riesgo ambiental y el análisis del impacto de sustancias tóxicas. En el presente trabajo se presenta un sistema de seguimiento y análisis mediante técnicas de visión artificial que permite cuantificar alteraciones en el comportamiento en peces expuestos a concentraciones subletales de sustancias tóxicas. El sistema permite la obtención de una serie de variables comportamentales a partir de un grupo de peces expuestos a una sustancia tóxica, en este caso el insecticida organofosforado clorpirifos, que posteriormente son analizadas para comprobar su desviación frente a un grupo control. Los resultados obtenidos muestran como las variables registradas proporcionan información muy valiosa sobre el comportamiento en peces y constatan que dicho sistema puede ser utilizado para caracterizar las respuestas comportamentales frente a la exposición de sustancias tóxicas y en la evaluación del riesgo ambiental. Palabras clave: Toxicología, Biomonitorización, Comportamiento en peces, Pesticidas, Clorpirifos, Movimiento. Abstract Water quality monitoring and analysis system through study of fish behavioral response to toxic compounds Behavioral alterations can be assesed as variables for sublethal toxicity tests, and serve as a tool for environmental risk assesement and analysis of toxicological impact. In order to investigate contaminant-induced behavioral alterations in fish, a video analysis system was designed to obtain relevant behavioral variables. Data from fish exposed to a reference toxicant, organophosphorus pesticide chlorpyrifos, are presented to exemplify alterations in fish behavior associated with exposure to this pesticide. The developed system provides valuable information on parameters associated with fish behavior and can be used to identify characteristic behavioral responses to a variety of toxicants and assist in risk assessment
The Need for a First-Order Quasi Lorentz Transformation
Abstract. Solving electromagnetic scattering problems involving non-uniformly moving objects or media requires an approximate but consistent extension of Einstein's Special Relativity theory, originally valid for constant velocities only. For moderately varying velocities a quasi Lorentz transformation is presented. The conditions for form-invariance of the Maxwell equations, the so-called "principle of relativity", are shown to hold for a broad class of motional modes and time scales. A simple example of scattering by a harmonically oscillating mirror is analyzed in detail. Application to generally orbiting objects is mentioned
An adaptive mobile application development framework
Abstract. Although wireless networks and mobile devices become popular these days, the diversity of mobile devices and unsteadiness of wireless networks still cause software development much trouble. Thus, when developing a mobile application, developers are forced to expose to these problems and to be familiar with these technologies and therefore it will spend a lot of time to write a mobile application. Furthermore, a mobile application often needs to be ported to different platform (for example from Java to .NET) which is also burdensome. In order to overcome these problems, the author proposes an adaptive framework to help developers build mobile application effortlessly and rapidly. The mobile application developed on this framework can run in different devices and operating system, so developers does not need to worry about portability. As a result, a mobile application developed on this framework can enjoy the benefit of "write once, run everywhere, and access any services."
Boundary knot method for Poisson equations
Abstract The boundary knot method is a recent truly meshfree boundary-type radial basis function (RBF) collocation scheme, where the nonsingular general solution is used instead of the singular fundamental solution to evaluate the homogeneous solution, while the dual reciprocity method is employed to the approximation of particular solution. Despite the fact that there are not nonsingular RBF general solutions available for Laplace-type problems, this study shows that the method can successfully be applied to these problems.
Online) An Open Access
ABSTRACT A water quality analysis was conducted to monitor the ground water of selected locations of Mathura city by evaluating the various physico-chemical parameters. Water samples from Krishna Nagar to Prabhat Nagar were collected and analyzed for physico-chemical parameters such as pH, total dissolved solids, total hardness, chlorides, turbidity and alkalinity. The results were compared with the drinking water standards of CPCB and BIS. The present study indicated that there is a need for regular monitoring of groundwater for physico-chemical characteristics in the area