International Journal of Human Capital Management (IJHCM)
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Detection of the Helicobacter pylori caga gene in gastric biopsies from dyspeptic patients using PCR method in Mataram General Hospital
No full textA polymerase chain reaction assay (PCR) for the diagnosis of Helicobacter pylori in human gastric biopsies from 44 dyspeptic patients was developed. From endoscopic diagnosis, the sample consisted of 4 patients with gastric cancer, 4 patients with duodenal ulcer, 3 patients with ventricular ulcer, 3 patients with both ventricular ulcer and duodenal ulcer and 31 patients with chronic gastritis. The H. pylori infection was diagnosed using nested PCR, which consisted of two primers of the urease gene fragment. From 44 specimens with urease positive, 39 specimens were positive for cagA strain (88,6%). This reflects a very high frequency of the cagA gene in the Helicobacter pylori infection. The meaning of this is still unclear. There was no significant difference in the cagA status of ulcer dyspeptic patient and non- ulcer dyspeptic patients. Key words: CagA gene, Helicobacter pylori, PC
Acute pancreatitis as a complication of dengue fever
No full textAcute pancreatitis is a rare complication of dengue fever that usually occurs without hyperglycemia. We report one patient of dengue fever with a complication of acute pancreatitis. A 28 year old male was referred from a private clinic to Dr. Cipto Mangunkusumo hospital, because of fever and abdominal pain since two days before admission. The physical examination showed slight fever and epigastric pain. The laboratory examination revealed leukocytosis, thrombocytopenia and increased levels of serum amylase and lypase. The diagnosis of dengue infection was made after the finding the IgM for dengue virus. After 12 days of hospitalization, the patient’s clinical signs and symptoms and laboratory findings were within normal limits. Key words: acute pancreatitis, dengue feve