World Nutrition Journal (Indonesian Nutrition Association - INA)
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Impact of an oral nutritional supplement on nutritional status in older adults with malnutrition: A randomized controlled trial : Oral Nutritional Supplements Improve Nutritional Status in Malnourished Older Adults.
Background: The aging population is expanding at an unprecedented rate, leading to a significant increase in the prevalence of malnutrition among older adults. Oral Nutritional Supplements (ONS) have emerged as a widely accepted strategy to address the nutritional needs of this demographic.
Objective: This study aimed to evaluate the impact of an ONS on the nutritional status of malnourished older adults.
Methods: This was an open-label, randomized-controlled, parallel-group, single-centered study. Recruitment criteria were age ≥60 years, and mini nutrition assessment-short form (MNA-SF) score ≤11. A total of 50 participants were randomly assigned to the intervention (IG) and control (CG) groups (1:1 ratio). The IG received 200 mL of ONS as a bedtime drink for 12 weeks, while the CG received 200 mL of water. Nutrition status, biochemical analysis, and dietary assessment were performed at the beginning and end of the study.
Results: Forty-two participants (IG: n=20, and CG: n=22) completed the study. After 12 weeks, the IG showed a significant improvement in the MNA-SF score (p<0.001) compared to the CG (p=0.118). The IG experienced a substantial increment in the vitamin D level (p=0.002). No significant improvements were found in the serum albumin and haemoglobin levels in either group. The intervention led to significant increases in daily intake of energy (p<0.001), carbohydrate (p=0.013), protein (p<0.001), and fat (p<0.001) in comparison to the control group.
Conclusion: Supplementing with an ONS, along with a regular diet, significantly improved nutritional status, some biochemical parameters, and daily intake of energy and macronutrients in older adults with malnutrition
Risk based feeding protocol in ICU
A risk-based feeding regimen in the ICU aims for optimal nutritional support by customizing feeding methods to the particular risk attributes of critically ill patients. These are the key components and concepts of this strategy. 1) Risk stratification: This includes the risk of malnutrition and feeding complications. 2) Feeding Initiation: For patients at high nutritional risk or with severe illness, early enteral nutrition (EN) including trophic feeding should begin within 24-48 hours after ICU admission
Association of dietary inflammatory index score with gestational weight gain in 22 to 28 weeks of pregnancy
Maternal mental health during pregnancy has a significant impact on early childhood development, but its association with child growth outcomes, notably stunting, has received less attention, particularly in Indonesia
Nutrient-rich food index 9.3 score and food choice values among female online food delivery users during COVID-19 pandemic
Background: The COVID-19 pandemic has transformed eating habits, leading to an increased reliance on online food delivery. It's crucial to comprehend the diet quality and food choices among female users during this period.
Objective: This study aims to explore the association between diet quality score and the food choice motives among female online food delivery users during the COVID-19 pandemic
Methods: This online cross-sectional study involved surveying 405 female users recruited through consecutive sampling. The Food Choice Values Questionnaire (FCVQ) was utilized to understand their food choices, while nutrient intake and diet quality were assessed using the Nutrient-Rich Food 9.3 Index Score (NRF 9.3). Subsequently, the collected data underwent both univariate and multivariate analyses. Potential biases might arise due to time constraints during the pandemic and reliance on self-reported online data. Moreover, the method used to measure nutrient intake might not be ideal for this demographic, lacking tailored tests. Nonetheless, it’s important to highlight that the survey underwent prior validation among Indonesian adults, affirming its broad applicability.
Results: Female users showed low average NRF 9.3 scores (241.67), indicating poor diet quality. Their prioritized food choice motives were also low. Significant associations surfaced between NRF 9.3 scores and food choice motives—tradition (p<0.01, r: 0.229), comfort (p<0.01, r: 0.223), organic (p<0.01, r: 0.231), safety (p<0.001, r: 0.162), weight control/health (p<0.01, r: 0.171), and income (p<0.05).
Conclusion: The NRF 9.3 score is likely to increase when there are higher scores for tradition, comfort, and organic factors, and when income exceeds the minimum regional wage
Development of Phil-HEI and its evaluation of the Filipino diet: 2018 expanded national nutrition survey
The Philippine Healthy Index (Phil-HEI) is a locally developed diet quality index. Patterned the American Healthy Eating Index (HEI), it aims to assess an individual’s diet quality through a scoring metric based on existing dietary guidelines.  
The differences of child feeding practices between working mothers and daycare staff in daycare
Child feeding practices between working mothers and daycare staff play an important role in children’s dietary intake. This study aims to compare child-feeding practices between working mothers and daycare staff. Additionally, the study explores the perspectives of working mothers, daycare staff, and management regarding their roles in child feeding practices to the children
Intermittent fasting-induced improving insulin resistance in healthy obese adults: A scoping review
Background: Obesity is a severe global public health problem linked to chronic noncommunicable disease and increased mortality. It has harmful effects on metabolic disorders via the insulin resistance pathway. Available guidelines recommend caloric reduction via intermittent fasting for obesity management. However, the available literature is less focused on the benefits of intermittent fasting on improved insulin resistance in healthy obese adults, especially related to an accumulation of free fatty acids. Therefore, a scoping review is necessary.
Objective: This review aims to collect evidence on the benefits of intermittent fasting on improved insulin resistance in healthy obese adults.
Methods: This scoping review followed the 5-step Arksey and O'Malley framework and was submitted following PRISMA ScR. Five electronic databases were thoroughly searched. Papers are included if they are eligible. The result was a synthesis of descriptive and narrative elements.
Results: 1117 papers were collected in total. Nine randomized controlled trial studies met the review's inclusion criteria. The papers included are sourced from reputable, relevant sources. As a whole, intermittent fasting appears to benefit improved insulin resistance in healthy obese adults. Intermittent fasting has been shown to reduce insulin levels while increasing insulin sensitivity, therefore improving insulin resistance.
Conclusion: Evidence suggests that intermittent fasting can help improve insulin resistance in healthy obese adults
The correlation of folic acid and homocysteine serum with vascular density and retinal non-perfusion area in diabetic retinopathy
Background : Diabetic Retinopathy (DR) is the most common microvascular complication of Diabetes Mellitus (DM). Homocysteine has been studied as a biomarker in DR, while folic acid exhibits anti-proliferative effects in DR.
Objective : To analyze the correlation between folic acid and homocysteine serum with vascular density and retinal non-perfusion area in healthy individuals and patients with diabetic retinopathy.
Methods : This is an observational study with a cross-sectional design, conducted in Dr. Kariadi Hospital and GAKI laboratory in Semarang in January 2023. This study included 60 samples: 15 healthy individuals, 15 patients with DM but no DR, 15 patients with Non-Proliferative Diabetic Retinopathy (NPDR), and 15 patients with Proliferative Diabetic Retinopathy (PDR). Patients were examined for serum folic acid and homocysteine using blood laboratory tests, vessel density and retinal non-perfusion areas using optical coherence tomography angiography (OCTA).
Results : There was a negative correlation with weak strength between folic acid levels and retinal non-perfusion area of the retina in all samples (Folic acid levels vs retinal non-perfusion area, p = 0.009, Spearman correlation = -0.335). There was a positive correlation with weak strength between folic acid levels and vascular density in all samples (Folic acid levels vs vascular density, p = 0.009, Spearman correlation = 0.337). There was a positive correlation with moderate strength between homocysteine levels and retinal non-perfusion area in all samples (Homocysteine levels vs non–perfusion area of the retina, p = 0.001, Spearman correlation = 0.426). There was a positive correlation with moderate strength between homocysteine levels and vascular density in all samples (Homocysteine levels vs vascular density, p = 0.001, Spearman correlation = -0.414).
Conclusion : There was a correlation between folic acid and homocysteine serum with vascular density and retinal non-perfusion areas
Effect of probiotic administration in adult atopic dermatitis patients: An evidence-based case report
Introduction: Atopic dermatitis (AD) is a chronic skin disease characterized by abnormal skin barrier function and heightened immunologic sensitization. Its incidence has surged recently, with approximately 60% of cases diagnosed within the first year of life. AD can persist or recur, significantly deteriorating the quality of life due to persistent itching and sleep disturbances. Individuals with AD are at increased risk of developing other atopic disorders like asthma and allergic rhinitis. Various dietary approaches, including low carbohydrate, calorie, and fat diets, have been associated with enhanced quality of life by regulating immune responses. Probiotics have been used as adjuvant therapy in allergic conditions, though their effectiveness varies due to the complex nature of allergies.
Method: A literature search was conducted using PubMed, Cochrane Library, and Google Scholar. MeSH terms, advanced search strategies, and predefined eligibility criteria were employed to identify relevant studies. Duplicate studies were excluded, and critical assessment tools and levels of evidence were defined per Oxford Center for Evidence-based Medicine standards.
Results: One systematic review and meta-analysis of randomized controlled trials (RCTs) met the PICO and eligibility criteria. The meta-analysis demonstrated that probiotics significantly decreased AD severity in adults, enhancing their overall quality of life. Other meta-analyses and systematic reviews supported that probiotics reduce clinical severity and improve life quality in adult AD patients.
Conclusion: Probiotic supplementation is a viable option to improve the quality of life for adult AD patients, offering potential therapeutic benefits in managing this condition
The effect of vitamin D supplementation on increasing CD4 levels in human immunodeficiency virus: evidence-based report
Introduction: Human immunodeficiency virus (HIV) is a retrovirus infection that attacks the immune system. According to world data in 2016, the number of HIV-infected patients reached 36.7 million, and 10 million people died due to acquired immunodeficiency syndrome (AIDS). Patients with HIV infection are susceptible to decreased levels of vitamin D (25(OH)D) by proinflammatory cytokines or as a result of the use of antiretroviral drugs. Vitamin D plays an important role in immune system, including reducing the production of pro-inflammatory cytokines and increasing the production of cathelicidin that inhibit viral replication. Oral vitamin D supplementation is an effort that can be made to increase vitamin D. To date, the relationship between vitamin D sufficiency and CD4 T cell count remains unclear, although most studies have shown a positive association. This study wanted to determine the effect of oral vitamin D supplementation on increasing CD4 levels in patients with HIV infection.
Methods: Literature search was carried out by advanced searching on Pubmed, Cochrane Library, and Science Direct using eligibility criteria determined by the authors.
Result: One systematic review and three randomized controlled trials (RCT) met the PICO and eligibility criteria that had been set. Three studies concluded that vitamin D supplementation can increase CD4 levels. One study shows that vitamin D supplementation dose of 5,000 IU daily could not increase CD4 levels.
Conclusion: Providing vitamin D supplementation at appropriate dose can increase serum vitamin D levels so that it can increase CD4 levels