3631 research outputs found
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Building the Machine: Student Rituals and Routines with Wally Shaw
No full textProfessional Development Workshop from March 9, 2024. Organized by Tina Holmes-Davis. Recorded for the Georgia College Center of Music Education.https://kb.gcsu.edu/cme_profdev/1030/thumbnail.jp
Manque de réussite : le préjudice dans le football français
No full textDespite being called The Beautiful Game, soccer in France has a few issues that take away from its beauty. This presentation aims to identify the causes and reasons behind the issues of racism, homophobia, and sexism which plague the French soccer scene. By looking at the causes of these from within French culture, history, and their society we can hope to understand why they exist as well as to establish the sources from which these issues arise
Promoting Physiologic Birth by Improving access to Doulas
Get PDFBirth in the United States (U.S.) leans towards a medicalized approach, overlooking the advantages of physiologic birth. Physiologic birth is a natural approach to childbirth, without medical interventions. Intrapartum nurses play an integral role in caring for women during labor by providing continuous labor support. Competing nursing tasks, exacerbated nursing shortages and increased nurse to patient ratios have made it increasingly challenging for intrapartum (IP) nurses to provide continuous labor support to their patients. The aim of this DNP project is to gain insight into the beliefs of IP nurses regarding childbirth and how these beliefs impact their approach to either medicalized or physiologic birth practices and whether they are supportive of doulas as part of the obstetrical team. This DNP project used a cross-sectional correlational study design of intrapartum nurses at three facilities in the southeastern U.S. A Likert-type questionnaire and an open-ended qualitative survey was administered to intrapartum nurses using a convenience sampling method. Among the project participants, the majority of IP nurses had birth beliefs supportive of physiologic birth practices. Older nurses with more years of experience and in rural geographic facility settings had higher scores indicating stronger physiologic birth beliefs. IP nurses minimally agreed they understood the formal training of doulas. Disseminated findings in these facilities will lead to collaboration and strategies to improve continuous labor support and improve utilization of doulas as part of the obstetrical team
The Treatment of “Lunacy” at Central State Hospital: The Long Shadow of “Moral Therapy: and Eugenics on Public Perception of Mental Health Facilities
No full textMilledgeville, Georgia is infamous for what is now known as Central State Hospital (CSH). Originally founded as the Georgia State Lunatic, Idiot, and Epileptic Asylum in 1842, it quickly became the largest in-patient mental health facility in the Southeast. In its time, CSH was considered innovative in its approach to mental health treatment and its treatment of their patients. However, many of those treatments utilized methods that would be considered at best questionable and at worst barbaric through a modern lens. The shadow cast from the history of mental facilities contributed to the stigma for seeking mental health care today. I analyze the use of moral therapy and eugenics in CHS’s past and how they impact the public perception of mental health facilities today
Restrictive Educational Policy and Minority Enrollment in Higher Education
No full textHow does policy limiting the discussion of sociopolitical issues and racial topics in educational settings affect minority enrollment in institutions of higher education? There is literature surrounding educational changes following elections and policy, but because of how recently legislation that restricts conversations about racial inequality have been implemented, there are no published research articles yet on how this new legislation targeting Critical Race Theory effects enrollment of minority students in institutions of tertiary education. I will be addressing this question using a Difference-in-differences design, which will allow me to analyze the pre period and post period based upon when legislation was passed and to have two different treatment conditions. My methodology will involve comparing student enrollment before legislation prohibiting or limiting sociopolitical topics and racial education, during the beginning of the education debacle, and enrollment for this current academic year. My hypothesis is that this type of racially restrictive legislation will result in a decrease in minority enrollment in the states with the policy. The data will be separated by racial identity of students enrolled in college to determine if there has been a shift since the new policy implementation
Stress-induced changes in 5ʹ end regulatory structures of the TP53 mRNA
No full textTumor suppressor TP53 is responsible for multiple regulatory functions including DNA repair, apoptosis, and cell cycle control. Loss-of-function mutations of the TP53 gene have been found in about 50% of all human cancers. Expression of the TP53 gene is regulated using highly diverse mechanisms with 13 known isoforms. Interestingly, the TP53 mRNA reportedly uses internal ribosome entry site (IRES)-mediated translation under cellular stress. Previous studies have implicated the role of structurally stable motifs in the 5ʹ untranslated region for mediating cap- independent translation. We present a secondary structure model of the TP53 5ʹ regulatory region. This region includes an alternate downstream start codon. Our model, based on SHAPE- MaP data from gently extracted total RNA of the A549 human lung carcinoma cell line using 5- nitroisatoic anhydride (5NIA), confirms previously observed secondary structure motifs. We then apply 5NIA to probe RNA in-cell to detect changes in SHAPE reactivity in live cells and compare reactivities with the cell-free model. We observe that the IRES-related motifs remain stable in unstressed live cells. Next, we treat cells with etoposide, an oncogenic stress inducer. Our initial studies detect measurable changes in SHAPE reactivity in a short stem-loop motif downstream of the standard AUG start codon. Prior reports indicate the role of IRES-transacting factors (ITAFs) including Hdm2 interacting with this mRNA region, and in certain cases correlating with the translation of an N-terminal truncated TP53. We outline future directions investigating the TP53 mRNA structure under different stress conditions, and also aim to identify changes in ITAF-interaction sites using RNP-MaP
Role of FGF2 mRNA 5ʹ UTR in cap-independent translation initiation
No full textThe FGF2 gene encodes the basic fibroblast growth factor which controls cellular growth, proliferation, and cell signaling. Under normal conditions, FGF2 mRNA is translated via cap-dependent translation. However, under certain stress conditions, an internal ribosomal entry site (IRES) reportedly bypasses typical regulation switching to cap-independent translation. Cancer cells overexpress FGF2 ultimately leading to tumor growth. Mechanistically, the reported switch from cap-dependent to cap-independent translation remains poorly described. In order to understand the regulation of the FGF2 IRES under cellular stress conditions, we investigate the secondary structure using the SHAPE-MaP chemical probing strategy under different chemically-induced stress factors. Here we describe our experimental strategy and present a secondary structure model of the FGF2 mRNA 5ʹ UTR built using gently extracted total RNA from the A549 human lung carcinoma cell line. We observe a complex arrangement of nucleotides throughout the targeted region (nucleotides 2-426). We compare the cell-free SHAPE reactivity profile with reactivity data from live cells using reagents 5NIA. Prior studies show that FGF2 uses four upstream CUG start codons which are activated in transformed and stressed cells. We present our initial reports on stress-induced cells, where we compare SHAPE profiles to identify the effect of stresses such as hypoxia, nutrient starvation, and heat shock. We aim to elucidate structural mechanisms corresponding to the effects of stress on FGF2 translation control. Lastly, we describe a workflow for future experiments involving DMS-MaP, a strategy for direct nucleotide base-pairing analysis, and RNP-MaP, an RNA-protein interactomics strategy to study the influence of IRES-transacting factors under stress conditions
How Accurately Can the NBA Combine Statistics Predict Players\u27 Performance in the NBA?
No full textThe National Basketball Association (NBA) hosts an event known as the Combine each year where college and international basketball players come to show off their skills/strengths to the coaches so that the coaching staff can strategically plan which player(s) they will pick at the NBA draft. There are numerous things that are measured in each player, including some measurements that seem unnecessary, but can actually play a role in the success of an NBA player. This project will be a deep dive into how the anthropometric characteristics and agility statistics of players entering the NBA affect player performance at the professional level. The predictors used in my analysis will not only include players’ height (which its advantage in basketball is quite obvious), but also their wingspan ratio, vertical reach, weight, body fat percentage, hand width/length, vertical leap, and 3-quarter court sprint. A player’s “per game” statistics including points, rebounds, assists, blocks, and steals will be used to determine the necessity and strength of certain predictors, along with number of championships, All-Star game appearances, and drafted status. This project will also divide the players into the five major positions of basketball in order to observe trends within each position
The use of Anglicisms in Social Media
No full textThe use of Anglicisms, or linguistic borrowings from English into other languages, has become more prevalent in the Spanish language with the increased use of social media in this current generation. With the surge in popularity of digital platforms, the way people communicate has undergone a transformation, leading to a mix of languages and a blending of traditional language distinctions. This shift poses challenges and opportunities for global connectivity, influencing how language evolves, individuals negotiate their identity, and cultural dynamics play out. This presentation will discuss Spanish words influenced by English across different social media platforms while considering demographic factors such as age and location. The presenters will highlight the main linguistic trends observed across various platforms and among different user groups. By shedding light on these linguistic dynamics, the presentation offers insights into the impact of this language mix on cultural expression and provides clarity on the ongoing changes in language and culture in the digital era. It will also discuss how the use of Anglicisms has affected the Spanish language used in social media and how it will continue to change
THRIVE Together: Fostering Inclusion, Friendships, and Academic Success on Campus
Get PDFGC THRIVE is an Inclusive Postsecondary Education (IPSE) Program whereby college-aged individuals with intellectual disabilities take GC courses with their non-disabled peers, work in on-campus internships, and develop friendships with their peers. In bringing them to campus, we are focused on providing them with opportunities and experiences that will help them become successful adults after college. This program developed out of many external (e.g., Georgia Council on Developmental Disabilities) and internal collaborations (e.g., Continuing and Professional Studies). The impact of this program has the potential to be far reaching, perhaps even farther reaching than traditional service-learning projects. While engaging students out in the community does impact them in meaningful ways, it does nothing to change the institution of higher education. Bringing THRIVE students to campus forces us to look inward as we contemplate these questions. If we truly value diversity and inclusion, what steps are we willing to take to make campuses more diverse and inclusive? What barriers do we need to address? THRIVE impacts each of us personally. THRIVE students learn college-level academic content, intern on-campus to learn work skills, and build true, authentic friendships. Faculty, staff, and students have changed their perspectives of students with intellectual disabilities. The THRIVE Program is one in which everyone stands to benefit as we work collaboratively to make meaningful change