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    3631 research outputs found

    Implementing Cards as a Tool to Expand End-of-Life Conversations

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    Starting an end-of-life conversation can be daunting for a healthcare provider. These conversations are often challenging and bring up complex emotions for the patient. The aging population is growing immensely, leading to an increased need for advanced care planning in the coming years. Advanced care planning and the discussions surrounding it are commonly limited to issues of cardiopulmonary resuscitation measures. In addition to this, the conversation needs to be focused on values and goals at the end-of-life. Current research shows that value-based end-of-life conversations allow patients to express issues that are important to them. This will allow each patient to have a unique and tailored experience that meets their needs. There are few interventions in the literature that expand end-of-life care conversations. Often interventions are lengthy and complex. The Go-Wish cards are a tool that can be implemented easily to expand the end-of-life conversation in a time sensitive way. This tool may assist healthcare providers in discovering their patients’ values and integrate them into their care. The purpose of this paper is to implement a tool in the home hospice setting to facilitate the expression of the hospice patients’ values and wishes for end-of-life care

    The Nuclear Role of Rpt1 in Long-Term Synaptic Plasticity

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    The hippocampus is the region of the brain responsible for the formation and storage of memory for places, events, and things. In order for memories to be stored for long periods of time, the connections between nerve cells called synapses must get stronger. The ability of the synapses to change in strength is termed synaptic plasticity which can last a few minutes (short-term) or for days and years or even a lifetime (long-term). Previous research pointed to the requirement of new gene transcription and protein synthesis for long-term synaptic plasticity. Research over the past several years indicates that protein degradation by the ubiquitin-proteasome pathway (UPP) is a key player in inducing long-term synaptic plasticity. In addition, new research suggests that apart from functioning in protein degradation, the proteasome may have a non-proteolytic role in assisting transcription. We hypothesize that the proteasome, made up of a 20S core and two 19S regulatory caps attached to each end of the core, plays a vital role in transcription that is necessary for maintenance of long-term synaptic plasticity. An experimental paradigm used to study long-term synaptic plasticity is called late phase long-term potentiation (L-LTP). Preliminary data show that the role of the proteasome in transcription may be essential for L-LTP. To understand the role of the proteasome in transcription, it would be necessary to identify the genes whose transcription is regulated by the proteasome during development of L-LTP. The research focused on a specific 19S subunit called Rpt1 and its nuclear translocation with a view to elucidate its transcriptional role. The experiments identified amino acid sequence elements critical for nuclear translocation of Rpt1 and revealed details of gene transcription possibly modulated by Rpt1.In combination with other ongoing projects and related research, our work is contributing to a mechanistic understanding of molecules critical for long-term synaptic plasticity that underlies long-term memory. This may assist in identifying novel therapeutic targets for memory loss that occurs in various neurodegenerative diseases

    Consecuencias sociales en el cine latinoamericano: alta visibilidad de lo queer

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    This presentation explores hegemonic societies in the Caribbean and the Southern Cone of Latin America as framed by the cultural phenomenon of high queer visibility in four films: Fresa y chocolate (1995) by Tomás Gutiérrez Alea and Juan Carlos Tabío, Antes que anochezca (2000) by Julian Schnabel, El beso de la mujer araña (1985) by Héctor Babenco, and Hoy quiero volver solo (2014) by Daniel Ribeiro. It examines the social consequences that each of the main characters must pay to their hegemonic societies because of this visibility. This research also makes a case for compulsive heterosexuality and how the heterosexist gaze does not apply to disabled individuals

    Teaching Students to Practice with Dr. Tina Holmes-Davis

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    https://kb.gcsu.edu/cme_profdev/1005/thumbnail.jp

    Theory refresher with Dr. David Johnson: 5 Whole steps and half steps

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    https://kb.gcsu.edu/highschoolwkshps/1007/thumbnail.jp

    Intro to Choral Programming with Dr. Jennifer Flory

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    https://kb.gcsu.edu/cme_profdev/1003/thumbnail.jp

    Theory refresher with Dr. David Johnson: 1 Pitch names

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    See the online activity here: https://www.musictheory.net/exercises/notehttps://kb.gcsu.edu/highschoolwkshps/1002/thumbnail.jp

    A Link between Psychopathy Affect and Instrumentality in Homicide

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    This study tests the hypothesis that psychopathy is more associated with instrumental homicides than mixed and reactive homicides, and explores relationships between Psychopathy Checklist-Revised (PCL-R) facet/item scores and different forms of homicide: instrumental (n = 130), mixed (n = 103), and reactive (n = 219) homicides. Instrumental homicides scored higher on facet 2 (p \u3c.01) but scored lower on facet 4 (p \u3c.1) compared to reactive homicides, whereas no facet scores differed between mixed and reactive homicides. Among the items of facet 2 (affective), remorselessness (item 6), and callousness (item 8) were predictive of instrumental homicide

    The perspective of artisan vendors\u27 resilience, dedication to product authenticity, and the role of marketing and community: 21st century

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    Purpose: This study creates new knowledge that addresses issues significant enough to warrant intellectual engagement. It fills a gap in the academic and practitioner literature by examining a profitable yet understudied cottage industry (artisan vendors). It examines marketing concepts that influence dedication to authentic craftsmanship and artisans\u27 willingness to continue in the industry. Design/methodology/approach: This study examines historical evidence and connects it with subjective and interpretive analyses from 29 in-depth interviews of today\u27s US artisan vendors to identify sustainable marketing best practices for the industry. Findings: Researchers uncovered factors behind artisan vendors\u27 willingness to stay committed to their craft and remain in the industry. From the findings of this study, marketing best practices (branding, brand communities and product adaptation while remaining authentic to their craft) were identified as tools for resilience and remaining a viable competitor in the marketplace. Originality/value: Historically, artisan vendors have been engaging in marketing practices before terms defined their activities. Thus, this study is original in that it contributes to the academic literature by first conducting an analysis of the history of an understudied cottage industry (artisan vendors) starting in the Mesopotamian Era. The key marketing factors discovered in the historical study contributing to the resilience of this industry were then used to conceptualize a qualitative study of the highly profitable US artisan vendor industry

    Inequities in Physical Activity Environments and Leisure-Time Physical Activity in Rural Communities

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    INTRODUCTION: Differential access to environments supportive of physical activity (PA) may help explain racial and socioeconomic disparities in leisure-time physical activity (LTPA) in rural communities. METHODS: We used baseline data from a mailed survey (N = 728) conducted in 2019 as part of an evaluation of The Two Georgias Initiative to examine the relationships among LTPA, sociodemographic characteristics, and perceived access to supportive PA environments (eg, areas around the home/neighborhood, indoor and outdoor exercise areas, town center connectivity) in 3 rural Georgia counties. RESULTS: More than half of respondents (53.5%) engaged in LTPA in the previous month. Perceptions of PA environments were generally neutral to somewhat negative. In multivariable models, overall PA environment was associated with LTPA (OR, 1.58; 95% CI, 1.06-2.35), as was annual household income \u3e50,000relativeto50,000 relative to ≤20,000 (OR, 2.72; 95% CI, 1.53-4.83) and race, with Black respondents less likely to engage in LTPA than White respondents (OR, 0.49; 95% CI, 0.29-0.85). Of the 5 PA environment domains examined, town center connectivity was significantly associated with LTPA (OR, 1.68, 95% CI, 1.20-2.36). Both the overall PA score (β = -0.014; 95% CI, -0.029 to -0.002) and town center connectivity (β = -0.020; 95% CI, -0.038 to -0.005) partially mediated associations between annual household income and LTPA. Areas supportive of PA around the home/neighborhood partially mediated the association by race (β = 0.016; 95% CI, 0.001-0.034). CONCLUSION: Findings lend support for investing in town centers and racially diverse neighborhoods to increase walkability and PA infrastructure as potential strategies to reduce inequities in LTPA

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