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Mary Carpenter Interviewed by Charlotte Aexel
Get PDFCharlotte Aexel interviews Mary Carpenter, author of Flannery O’Connor: A Girl Who Knew Her Own Mind, on discovering O’Connor and the impact of Milledgeville on her life.
Listen to the podcast version here:
YouTube
https://youtu.be/Qc_iNAdUDNs
Spotify
https://spotifyanchor-web.app.link/e/R5UTAVATwNbhttps://kb.gcsu.edu/collectingthepast/1018/thumbnail.jp
Church Member List
Get PDFThis is a list of church members for the First Presbyterian Church of Milledgeville. This information is not listed, but member names were cross-referenced with one of the other items in this collection to confirm that this is the church this list belongs to. Four pages, each only printed on the front of the sheet. The first page is a list of inactive elders and deacons, followed by three pages of resident church members.https://kb.gcsu.edu/info3402-2024/1006/thumbnail.jp
Presbyterian Homes Mothers\u27 Day Offering
Get PDFTwo-sided flyer for the Presbyterian Homes Synod of the Southeast advertising a Mothers\u27 Day offer. Folded to make four pages. Yellow with green text, images, and border.https://kb.gcsu.edu/info3402-2024/1009/thumbnail.jp
Does Combine 40-Time Affect Player Performance in the NFL?
No full textThe NFL (National Football League) generated $18.6 billion in revenue in 2022, and the best tool teams have to improve their quality—and in turn, value—is at the NFL Draft. Teams use the NFL Combine as a guide for which players to draft. The 40-yard dash is generally viewed as the most impactful test on draft position. I test whether 40-yard dash times affect player performance in the NFL, and whether NFL teams are overvaluing the physical tests at the NFL Combine. Preliminary results from my research indicate that 40-yard dash times have a very positive impact on player performance at the NFL level
The Effect of Students\u27 Performance on the Scores from Rate My Professor
No full textWhen students register for their classes, they often form predictions about the potential grades they will earn in the course. Factors such as RateMyProfessor scores, the class level, and the department offering the course influence these expectations. The question arises: are these just assumptions or sound projections? This project takes data from Georgia College & State University and RateMyProfessor and studies the association between the grades students earn and RateMyProfessor scores. Utilizing the software RStudio and its statistical tools, we analyzed the data collected on the courses, grades, and professor ratings. This project allows for a deeper understanding of the dynamics between student grades, scores from RateMyProfessor, and course characteristics
Post Developmental Mathematics: Experiences in College Algebra for STEM Students
Get PDFStudents majoring in a STEM discipline whose sequence of collegiate mathematics begins at the developmental level follow a unique progression towards degree completion. With an elongated sequence of mathematics courses, these students have already had exposure to collegiate mathematics when enrolling in a college algebra course. A structured multiple case study provided a context for understanding students’ perceptions about how their developmental mathematics experiences may have influenced their experiences in college algebra. Qualitative data was gathered through interviews with three students who are majoring in a STEM field of study. The selected students had similar quantitative literacy expectations for their degrees but differed in the types of developmental mathematics experiences they had before or during their enrollment in a college algebra course. The goal of the study was to generate an understanding of these students’ experiences in college algebra and how their various experiences in developmental mathematics may have contributed to them. For these participants, having previous developmental mathematics seemed to influence awareness of productive study habits, and the importance of getting help
Cherokia georgiana mitogenome sequencing and analysis
Get PDFDespite the vast diversity of millipedes, complete genomic and mitogenomic data available in public databases is limited, hindering comprehensive studies on their classification, evolution, and genetics. Among the underrepresented taxa are the Xystodesmidae, a family comprising approximately 500 species with minimal mitogenomic data, and no complete genomes sequenced. Our research involves sequencing the mitochondrial genome of Cherokia georgiana, a representative of this diverse family with interesting traits that are not clearly defined at a genetic level. This research also serves as a pilot study to develop DNA extraction methods and protocols for whole genome sequencing. Multiple DNA extraction kits and techniques were evaluated to optimize the yield of high-quality, high molecular weight (HMW) DNA suitable for sequencing. We assess the quality of next-generation sequencing (NGS) libraries using spectrophotometry (ThermoFisher Scientific Nanodrop), fluorometry (Invitrogen Qubit 4.0), and automated electrophoresis (Agilent TapeStation 4200). This work outlines the research strategies and protocols employing the Oxford Nanopore Technologies (ONT) MinION Mk1B platform for long read sequencing. We employed Dotmatics Geneious Prime software (Version 2023.2.1) and used the reference species data from Appalachioria falcifera to assemble the mitogenome. We generated a mitogenome map of C. georgiana, analyzed predicted structures of mitochondrial tRNA, and conducted basic phylogenetic analysis using the cytochrome c oxidase subunit I (COX1) genes and full mitogenomes published to GenBank. Future experiments will use the extraction methods described in this paper and will apply the PacBIO platform for whole genome sequencing to further enhance our knowledge of millipede genomics
The Role of Adenovirus Protein in the DNA-PK-dependent DNA Damage Response
No full textAdenovirus serotype 5 (Ad5) is a double-stranded (ds) DNA virus that causes upper respiratory infections and conjunctivitis. The Ad5 viral genome can be broken down into 5 early and 5 late regions. An important viral protein of the E4 region, E4 11k, aids in the manipulation shutdown of host cell machinery to allow for viral replication by stimulating late mRNA splicing and preventing the inhibition of viral DNA replication. One mechanism is through the inhibition of the DNA damage response (DDR). Part of the DDR is responsible for repairing double-stranded DNA breaks (DSBs) through non-homologous end joining. DNA-dependent protein kinase (DNA-PK) facilitates this type of DSB repair and activates further DDR. During an infection, Ad5’s linear dsDNA genome triggers the DSB repair pathway. DDR tries to “repair” the viral genome resulting in the concatenation and inactivation of the virus. Ad5, however, has evolved mechanisms to prevent the DDR from functioning normally, allowing effective infection. Previously, E4 proteins have been shown to regulate the activation of DNA-PK by autophosphorylation. In this study, we aim to determine if E4 11k can inhibit DNA-PK activation. To determine if E4 11k can inhibit DNA-PK activation, wWe pre-treated HeLa (cervical cancer) cells with E4 11k or, Nu7441 (a known DNA-PK activation inhibitor) treatment and then induced DSBs with the chemotherapy drug, etoposide. We then analyzed DNA-PK activation based on the level of phosphorylation by Western blotting. To induce DSBs, we used the chemotherapy drug, etoposide. It has also been shown that etoposide treatment and DNA-PK activation inhibition result in cancer cells becoming less adherent and remove their ability to repair the DNA damage. These findings suggest a potential mechanism for which E4 11k can be used as a novel chemosensitizer for therapy-resistant cancer cells
The Fire that Made Me Grow Up
Get PDFThis is a story of a Boy Scout campout going wrong, and the impact the events of that night had on the author
Aquagenic Urticaria
No full textAquagenic urticaria, a rare dermatological condition, is defined by localized hive and pruritus upon skin contact with water, regardless of the temperature or type. In simpler words, this condition is an allergy to water. When an individual with this condition is exposed to water, they develop red itchy hives. Even with the major impact on the daily lives of these patients, this allergy is significantly under-researched in the medical field, leading to limited treatment options that are often reliant on trial and error. Individuals that have been diagnosed deserve a chance at living a regular life, and to achieve that we need to conduct more research to better understand how it works, have better management strategies, and improve the quality of life that they experience. This research proposal is looking to improve the current gap in knowledge within the medical field, focusing on diagnostic testing, management, and treatment options. There is also a need to raise awareness of this condition as many people have never even heard of it. Raising awareness will provide information for those currently experiencing these symptoms, as well as assist physicians in diagnosing, testing, and treatment plans. (First-Year Writers\u27 Showcase