Mountain Scholar (Digital Collections of Colorado and Wyoming)
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Genetic background and experience affect courtship behavior in male Trinidadian guppies (Poecilia reticulata)
Full text link2023 Spring.Includes bibliographical references.An animal's behavior may be shaped by its genetics and life experience, but the extent to which each of these factors contributes to determining behavioral phenotypes is an outstanding question in biology. Mating behaviors are of particular interest due to their importance in determining fitness. We sought to investigate the genetic architecture of mating behaviors and their plasticity in response to mating experience. Trinidadian guppies (Poecilia reticulata) occur in streams with either high or low predation rates. This genetic background has shaped the evolution of many behavioral phenotypes, including those involved in male courtship strategy. We observed male guppies from high predation, low predation, and intercross populations in their first encounter with a female, then later repeated the encounter to observe how experience affects mating behaviors. We recorded occurrences of three behaviors – sigmoids, forced copulation attempts, and gonopodial swings – to determine how they are affected by sexual experience and genetic background. We found that the frequencies of sigmoids and gonopodial swings vary depending on genetic background and experience. Our findings support existing literature demonstrating that mating behaviors respond plastically to experience. We also found that intercross guppies matched the gonopodial swing and sigmoid frequency phenotypes of the QH genetic line, suggesting that these behaviors may be controlled by loci that are dominant in the high-predation population
Hydrophobic vanadium complexes for use in anticancer activity
No full textIncludes bibliographical references.2023 Spring.This dissertation contains the development, synthesis, and characterization of vanadium metal complexes in both biological environment and organic solutions for the purpose of novel medical treatments. As cancer is a disease that causes uncontrollable growth of mutated cells over time, treatments need to also improve to account for an ever-increasing cancer types. Although platinum-based drugs have found successful in treating multiple forms of cancer, inorganic metal based drugs are relatively uncommon in the medical field. It was found in 2020, that a vanadium compound was more potent than cisplatin and efforts were made to investigate and improve that compound. The compound is a ternary V(V) complex that consists of VOL1L2 where L1 is N-(salicylideneaminato)-N'-(2-hydroxyethyl)ethane-1,2-diamine and L2 is 3,5-di-tert-butylcatechol. It is believed that that hydrophobicity of the catechol ligand was significant in keeping the compound intact long enough to cause cytotoxicity in bone cancer cells. In Chapter 1, the biological effects of vanadium and the reasoning that vanadium may be used as a potent medical treatment for various illnesses such as bone cancers, brain cancers and/or tuberculosis are investigated. Chapter 2 describes the synthesis and characterization of halogenated version of the original vanadium Schiff base complexes to test how electronegativity affects the activity as well as testing how modification of the salicyaldehyde portion affects the metal complex. Chapter 3 reports the development of adamantanol catechol ligands to improve hydrophobicity in the vanadium Schiff base complex. Chapter 4 explains the speciation of working with a metal complex in a biological system by comparing two different vanadium systems and how they hydrolyze and form multiple different species in various environments. Chapter 5 summarizes the conclusions and proposes future works based on the research done that can move new projects forward
Tylin Holzer: capstone
No full text2023 Spring.Colorado State University Art and Art History Department capstone project.Capstone contains the artist's statement, a list of works, and images of works.The artist's statement: My artworks are within the dichotomy of aiming to solve problems and communicate complicated ideas with easily digestible graphics and experimenting with the fun and powerful features in Photoshop to manipulate reality and create anything I want to, usually photorealistic surrealism, scenes of the impossible make you want to look twice and ask, "what's happening?" I hope for my work to draw and keep someone's attention. I am interested in social justice and spreading awareness of issues in the world through meaningful and symbolic design. I strive to leave an impression and give the audience a challenging idea to leave with after viewing my work
Principles of Macroeconomics 2e support material for OpenStax textbook: week 2, chapter 6 - OER project materials
No full textMissing weeks are exam review weeks. There is a discussion prompt but no recitation material for week 4 (exam review).ECON 204.Week 2 discussion: Measuring GDP (chapter 6). The material included here was developed to support the use of the OpenStax textbook Principles of Macroeconomics 2e. The material includes two components: (1) weekly discussion prompts that were developed for use on online discussion boards; and (2) weekly recitation worksheets and answer keys.Please see online textbook: https://openstax.org/details/books/principles-macroeconomics-2e.The materials were collected for the OER project funded by the Colorado OER Council Grant (AY 2021)
Composing place: digital rhetorics for a mobile world
No full textIncludes bibliographical references and index.Composing Place proposes an innovative approach to engaging with the compositional affordances of mobile technologies. Jacob Greene utilizes a rhetorical framework through which writers can leverage the affordances of new technologies and develops this framework by drawing on theoretical approaches within rhetorical studies, multimodal composition, and spatial theory.--Provided by publisher