Jurnal Universitas Abdurrab
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Formulasi dan Aktivitas Antioksidan Krim Astaxanthin dengan Gelatin Kulit Ikan Patin (Pangasius hypophthalmus) sebagai Penstabil
Full text linkAstaxanthin has antioxidant activity, like other caratenoid compounds. Astaxanthin can protect cells or tissues from oxidative stress-induced damage. This research aims to formulate an astaxanthin cream preparation with the addition of catfish skin gelatin as a stabilizer and evaluate the characteristics of the cream preparation as well as testing the antioxidant activity of astaxanthin and the cream preparation using the DPPH method. Cream preparations are made with varying concentrations of 0; 0.05; 0.1 and 0.2% are named formulas F0, F1, F2, and F3 respectively. Evaluation of cream preparations includes organoleptic observations, homogeneity tests, pH tests, spreadability tests, and viscosity. The results of the organoleptic examination for each formula F0, F1, F2 and F3 are white, pink, red and brick red respectively, all formulas are odorless and are in semi-solid form. The homogeneity test showed that all preparations were homogeneous, the average pH range of the preparations was 6.40 ± 0.10 to 6.46 ± 0.05, the spreadability test was between 5.03 ± 0.05 to 5.16 ± 0.15 cm, viscosity 4984±177 to 6915±134. The evaluation results of the astaxanthin cream preparation have met the requirements. In testing the antioxidant activity of astaxanthin, the IC50 value was 3766.62 ppm, which was classified as inactive, and ascorbic acid as a comparison had an IC50 value of 6,799 ppm, which was classified as very strong. In the antioxidant test of the astaxanthin cream preparation, no antioxidant activity was detected and Garnier cream as a comparison produced an IC50 value of 19512334.96 ppm which was classified as inactive.Astaxanthin memiliki aktivitas antioksidan, seperti halnya senyawa karatenoid yang lain. Astaxanthin dapat melindungi sel atau jaringan dari kerusakan yang diinduksi stres oksidatif. Penelitian ini bertujuan untuk memformulasikan sediaan krim astaxanthin dengan penambahan gelatin kulit ikan patin sebagai penstabil dan mengevaluasi karakteristik sediaan krim serta melakukan pengujian aktivitas antioksidan astaxanthin dan sediaan krim dengan metode DPPH. Sediaan krim dibuat dengan variasi konsentrasi 0; 0,05; 0,1 dan 0,2% masing-masing diberi nama formula F0, F1, F2, dan F3. Evaluasi sediaan krim meliputi pengamatan organoleptik, uji homogenitas, uji pH, uji daya sebar, dan viskositas. Hasil pemeriksaan organoleptik setiap formula F0, F1, F2, dan F3 berturut-turut yaitu berwarna putih, merah muda, merah dan merah bata, semua formula tidak berbau dan berbentuk semi padat. Uji homogenitas menunjukkan semua sediaan homogen, rentang pH rata-rata sediaan 6,40±0,10 sampai 6,46±0,05 , uji daya sebar antara 5,03±0,05 sampai 5,16±0,15 cm, viskositas 4984±177 sampai 6915±134. Hasil evaluasi sediaan krim astaxanthin tersebut telah memenuhi persyaratan. Pada pengujian aktivitas antioksidan astaxanthin dihasilkan nilai IC50 3766,62 ppm tergolong kategori tidak aktif dan asam askorbat sebagai pembanding memiliki nilai IC50 6,799 ppm tergolong kategori sangat kuat. Pada pengujian antioksidan sediaan krim astaxanthin tidak terdeteksi aktivitas antioksidan dan krim Garnier sebagai pembanding dihasilkan nilai IC50 19512334,96 ppm tergolong kategori tidak aktif
HUBUNGAN KEJADIAN HIPERTENSI DENGAN PROTEIN URINE PADA IBU HAMIL TRIMESTER III DI RSUD dr. SOEDIRMAN KEBUMEN
Full text linkPrevelensi penyakit hipertensi saat kehamilan adalah 2,6 - 7,3% dari keseluruhan kejadian kehamilan yang dapat memiliki risiko bagi ibu hamil yang biasa disebut dengan Angka Kematian Ibu (AKI). Hipertensi saat kehamilan ialah salah satu dari penyebab kematian maternal yang bisa dideteksi secara dini melalui test protein urine. Protein urine adalah tanda penting dari preeklampsia yang disebabkan oleh kapasitas tubulus ginjal yang tidak maksimal untuk mereabsorbsi protein. Berdasarkan penelitian Wulandari et al (2022) yang mengutarakan bahwa terdapat hubungan yang signifikan antara protein urine terhadap tingkat tekanan darah pada ibu hamil TM III di Puskesmas Madukara I Banjarnegara dengan p=0.003. Tujuan penelitian untuk mengetahui hubungan kejadian hipertensi dengan protein urine pada ibu yang hamil pada TM III di RSUD dr. Soedirman Kebumen. Metode penelitian menggunakan Observasional Analitik melalui rancangan Cross-Sectional dengan sampel yang digunakan sebanyak 40 orang, dilaksanakan pada bulan Mei - Juli 2023 di Laboratorium RSUD dr. Soedirman Kebumen. Berdasarkan penelitian ini diperoleh nilai p=0.052 (p>0.05), sehingga dapat ditarik kesimpulan bahwa antara kejadian hipertensi dengan protein urine pada ibu hamil TM III di RSUD dr.Soedirman Kebumen tidak terdapat hubungan yang signifikan.
Kata Kunci : Hipertensi, Ibu hamil TM III, Protein urineAbstract
The prevalence of hypertension during pregnancy is 2.6 - 7.3% of all pregnancy incidents which can have risks for pregnant women, which is usually called the Maternal Mortality Rate (AKI). Hypertension during pregnancy is one of the causes of maternal death which can be detected early through a urine protein test. Urine protein is an important sign of preeclampsia which is caused by the kidney tubules not having optimal capacity to absorb protein. Based on research by Wulandari et al (2022) which states that there is a significant relationship between urine protein and blood pressure levels in TM III pregnant women at the Madukara I Banjarnegara Community Health Center with p=0.003. The aim of the study was to determine the relationship between the incidence of hypertension and urine protein in pregnant women in TM III at RSUD dr. Soedirman Kebumen. The research method used Observational Analytical through a Cross-Sectional design with a sample of 40 people, carried out in May - July 2023 at the Laboratory of RSUD dr. Soedirman Kebumen. Based on this research, a value of p=0.052 (p>0.05) was obtained, so it can be concluded that there is no significant relationship between the incidence of hypertension and urine protein in TM III pregnant women at Dr. Soedirman Hospital, Kebumen.
Keywords: Hypertension, Third Trimester pregnant women, urine protein
Peran Harga Diri Terhadap Ketidakpuasan Bentuk Tubuh Remaja Perempuan
Full text linkBody dissatisfaction is a serious phenomenon that requires precautions because it generates a serious of health complications, including impaired well-being. Self-esteem is one of the factors that can predict body dissatisfaction.This study aims to determine the role of self-esteem to body dissatisfaction in adolescent female. There are 250 adolescents female determined in this study using a purposive sampling technique. The BSQ-34 from Cooper et al. (1987) was applied to assess body dissatisfaction and the state self-esteem scale from Heatherton & Polivy (1991) was used to assess self-esteem. The regression model indicates r= -0.345, F= 16,996, B= -0,321 (p<0,000), which is means that self-esteem has a very significant role in predicting body dissatisfaction in adolescent females. These findings indicate that if adolescents have high self-esteem then dissatisfaction with their bodies is low, conversely if adolescents' self-esteem is low then adolescents will experience high body dissatisfaction. Appearance is the aspect of self-esteem that contributes the most to predicting body dissatisfaction, with r = -0,386,( p <0,000). Negatif appraisal of physical appearance can cause highest body dissatisfaction in female. That is the reason why it is important to have a possitive appraisal to avoid body dissatisfaction in adolescent female
Strategi Koping Remaja Mengatasi Kesepian
Full text linkLoneliness is a mental health issue. The aim of this research is to understand how adolescents recognize, feel and overcome loneliness. The research was conducted using a descriptive qualitative approach, involving 38 adolescent (21 girls and 17 boys) who experienced loneliness in three junior high schools (SMP) in Pekanbaru. The data was obtained through online interviews using Google Form. Data analysis uses thematic analysis techniques. The results showed that junior high school adolescents used various coping strategies to overcome loneliness. The most commonly used strategy in grades 8 and 9 is focusing on emotions, while in grade 7 focuses more on problems. The results of this research provide an overview of loneliness and how to overcome it from an adolescent perspective so that it can help the process of counseling and therapy for loneliness in adolescents. Further research is needed to understand the factors that influence adolescents' coping strategies in overcoming loneliness
Hubungan Penggunaan Antidiabetes Oral terhadap Nilai Klirens Kreatinin pada Pasien Diabetes Melitus Tipe 2 di Rumah Sakit Umum di Jakarta
Full text linkDiabetes mellitus can cause various complications such as stroke, coronary heart disease, peripheral artery disease, retinopathy, neuropathy and nephropathy. Choosing the right drug in diabetes mellitus patients is very important because most antidiabetic drugs are excreted through the kidneys, so it is necessary to monitor creatinine clearance values as an indicator of impaired kidney function. The aim of this research is to find out the relationship between the use of oral antidiabetics and creatinine clearance values in type 2 diabetes mellitus. This research is an observational analytical study with a cross-sectional data collection method on patients type 2 diabetes mellitusbetween January 2023 - December 2023 at a public hospital in Jakarta. This study obtained 39 patients, including the majority of patients who used oral anti-diabetics were women, 56.4%.The largest age was in the range 46 – 55 years at 38.5%. The most common type of drug is a combination of two drugs glimepirid + metformin as much as 35.9% and the creatinine clearance value in type 2 diabetes mellitus patients is a klirens kreatinin value < 90 mL/min/1.73m2 of 66.7%. The results of the chi-square test obtainedp=0.093. Based on the values obtained, there was no significant relationship between the use of oral antidiabetics and creatinine clearance values.
Diabetes melitusdapat menyebabkan terjadinya berbagai komplikasi sepertistroke, penyakit jantung koroner, penyakit arteri perifer, retinopati, neuropati,dan nefropati. Pemilihan obat yang tepat pada pasien diabetes melitussangatlah penting karenasebagianbesarobat antidiabatesdiekskresikanmelaluiginjalsehinggadiperlukanpemantauan nilai klirens kreatinin sebagai indikator gangguan fungsi ginjal. Tujuan penelitian ini untuk mengetahui hubungan penggunaan antidiabetesoral terhadap nilai klirens kreatininpada pasien diabetes melitustipe 2. Penelitian ini merupakan penelitian analitik observasional dengan metode pengambilan data secara cross sectionalpada pasien diabetes melitus tipe 2 periode Januari 2023 – Desember 2023 di salah satu rumah sakit umum daerah Jakarta. Penelitian ini memperoleh39 pasien, meliputi pasienterbanyak yang menggunakan antidiabetesoraladalah perempuan sebanyak 56,4%, usia terbanyak berada pada rentang 46 – 55 tahun sebesar 38,5%. Jenis obat terbanyak yaitu kombinasi dua obat glimepirid + metformin sebanyak 35,9% dan nilai klirens kreatinin pada pasien DM tipe 2 yaitu nilai klirens kreatinin < 90 mL/min/1,73m2 sebesar 66,7%. Hasil uji chi-squarediperoleh p=0,093, berdasarkan nilai yang diperoleh tidak ada hubungan yang signifikan antarapenggunaan antidiabetes oraldengan nilai klirens kreatinin
Evaluation of Antibiotic Use in patients at Pekan Heran Community Health Center using the Anatomical Theraupetic Chemical/Defined Daily Dose and Drug Utilization Method
Full text linkAntibiotik merupakan salah satu obat yang penggunaannya tertinggi di dunia. Penggunaan antibiotik yang relatif tinggi dapat meningkatkan resiko resistensi antibiotik. Berdasarkan beberapa penelitian di Indonesia penggunaan antibiotik di beberapa puskesmas menunjukan banyaknya penggunaan antibiotik. Penelitian ini bertujuan untuk mengetahui bagaimana penggunaan antibiotik di puskesmas Pekan Heran pada tahun 2019-2022 dengan metode ATC/DDD dan melihat perubahan profil penggunaan antibiotic berdasarkan profil DU 90% yang dihitung dalam satuan DDD/1000 KPRJ. Dalam penelitian ini terdapat 8 antibiotik yang digunakan di Puskesmas Pekan Heran yaitu amoksisilin, clindamisin, eritromisin, cefixime, kontrimoksazol, metronidazol, kloramfenikol dan cefadroksil. Pengumpulan data di dapat dari Rekam Medik pasien Puskesmas Pekan Heran, pengolahan data menggunakan metode ATC/DDD yang diolah menggunakan microsoft excel. Hasil penelitian ini menunjukan kuantitas penggunaan antibiotic mengalami fluktuatif selama periode 2019-2022. Penggunaan obat antibiotic tertinggi yaitu pada tahun 2019 sebesar 708,233 DDD/1000 KPRJ, dan penggunaan terendah yaitu pada tahun 2021 sebesar 1,157 DDD/1000 KPRJ. Profil penggunaan antibiotik di Puskesmas Pekan Heran periode 2019-2022 berdasarkan DU 90% yaitu amoksisilin, eritromisin dan metronidazol. Amoksisilin adalah obat yang paling tertinggi yang digunakan dengan persentase pada tahun 2019 sebesar 48,006%, tahun 2020 sebesar 58,054%, tahun 2021 sebesar 27,072% dan tahun 2022 sebesar 28,437%.Antibiotics are one of the highest used drugs in the world. Relatively high use of antibiotics can increase the risk of antibiotic resistance. Based on several studies in Indonesia, the use of antibiotics in several Public health center shows the high use of antibiotics. This study aims to find out how antibiotics are used at the Pekan Heran health center in 2019-2022 using the ATC/DDD method and to see changes in the profile of antibiotic use based on the 90% DU profile which is calculated in units of DDD/1000 KPRJ. In this study, there were 8 drugs used at Pekan Heran Public Health Center, namelyamoxicillin, clindamyycin, erythromycin, cefixime, contrimoxazol, metronidazole, chloramphanicol and cefadroxil. Data collection was obtained from the Pekan Heran Public health center. The data processing uses the ATC / DDD method which is processed using Microsoft Excel. The results show that the quantity of antibiotic use has always fluctuating during the 2019-2022 period. The highest use of antibiotic drugs was in 2019 amounting to 708,233 DDD / 1000 KPRJ, and the smallest use was in 2021 amounting to 1,157 DDD / 1000 KPRJ. The profile of the use of antibiotic drugs at the Pekan Heran Public health centerfor the period 2019-2022 was based on DU90%, namely amoxicillin, erythromycin and metronidazole. Amoxicillin is the highest drug used with a percentage in 2019, namely 48,006%, in 2020 amounting to 58,054%, in 2021 it was 27,072%, in 2022 it was equal to 28,437
Analysis of Calcium Levels in Maman and Fermented Maman (Cleome gynandra L)
Full text linkKalsium merupakan salah satu asupan mikronutrien yang penting untuk mencegah terjadinya kejadian stunting. Kalsium berperan dalam pertumbuhan tulang. Maman (Cleome gynandra L) merupakan tanaman lokal yang tumbuh di provinsi Riau dan digunakan oleh masyarakat setempat sebagai makanan lokal yang difermentasikan. Untuk memanfaatkan tanaman lokal ini perlu dianalisis zat gizi yang dimilikinya, antara lain kadar kalsium. Analisis kalsium dilakukan dengan metode deskriptif kuantitatif menggunakan instrumen spektrofometer serapan atom. Validasi metode spektrofometri serapan atom diperoleh nilai koefisien korelasi (r) 0,9997 dengan kadar kalsium dalam daun maman dan fermentasi maman adalah 3132,33 mg/g dan 1976,31 mg/gCalcium is an important micronutrient that helps prevent stunting. It plays a crucial role in bone growth. Maman (Cleome gynandra L.) is a local plant that grows in the Riau province and is used by local people as a fermented food. To utilize this local plant, it is necessary to analyze its nutrients, including calcium levels. Calcium analysis was carried out using a quantitative descriptive method with an atomic absorption spectrophotometer. Validation of the atomic absorption spectrophotometry method yielded a correlation coefficient (r) of 0.9997, with calcium levels in maman leaves and fermented maman being 3132.33 mg/g and 1976.31 mg/g, respectively
EDUKASI ILMU GEOGRAFI TERAPAN: BIOGEOGRAFI PADA MURID XII IPS SMA IT NUR HIDAYAH
Full text linkBiogeografi merupakan salah satu cabang ilmu terapan dalam geografi yang mempelajari persebaran organisme hidup dan ekosistemnya yang terkumpul dalam suatu komunitas hayati di sebuah wilayah secara geografis. Kajian tentang biogeografi memiliki peranan penting dalam peruntukannya karena terhubung dengan ilmu biologi, pertanian, maupun kehutanan seperti pemahaman konteks evolusi organisme yang dilihat secara geografis, konservasi keanekaragaman hayati, rekayasa lingkungan, dan aplikasinya pada bidang pertanian dan kehutanan. Ilmu geografi merupakan bagian dari ilmu sosial. Tetapi, subjek dari ilmu sosial yang diajarkan pada kurikulum sekolah di Indonesia tidaklah menyeluruh. Kenyataanya, subjek ilmu sosial dari ilmu geografi terintegrasi dengan konsep ilmu sosial, kemanusiaan, ilmu alam,dan bahkan kombinasi berbagai isu-isu. Sehingga, adanya kemungkinan kurangnya kompetensi yang dibutuhkan bagi siswa dalam menunjang kelanjutan studi setelah lulus nantinya. Kegiatan ini dilakukan melalui seminar yang diadakan secara offline bertempat di SMA IT Nur Hidayah. Peserta diikuti oleh seluruh siswa kelas XII IPS berjumlah 83 siswa. Sebanyak 96 % siswa menyatakan puas dan merespon baik kegiatan ini karena memperoleh informasi yang baru dan belum ada selama kegiatan belajar mengajar di SMA secara umum. Total 85 % persen dari siswa mengungkapkan pentingnya materi kajian yang disosialisasikan.Biogeography is a branch of applied geography that studies about distribution of living organisms and their ecosystems in a biological community in a geographic area. Biogeography has an important role because it is connected to biological, agricultural and forestry sciences, such as understanding the evolutionary of organisms from geographic point of view, biodiversity conservation, environmental engineering and its application in the fields of agriculture and forestry. Geography is part of the social sciences. However, the subjects of social science taught in the Indonesian school curriculum are not comprehensive. In fact, the social science subject of geography is integrated with the concepts of social sciences, humanity, natural sciences, and even a combination of various issues. Thus, there is a possibility of a lack of competencies needed for students to advanced their studies. This activity was carried out through a offline seminar at SMA IT Nur Hidayah. The participants were students of class XII IPS total 83 students. As 96% of students were satisfied and responded well to this activity because they obtained new information that was not available during teaching and learning activities in high school in general. A total of 85% percent of students expressed the importance of study material
UPAYA PENCEGAHAN STUNTING PADA IBU HAMIL SERTA PENDIDIKAN KESEHATAN KADER DI PUSKESMAS MINAS
Full text linkDi Indonesia, mengatasi masalah gizi buruk, khususnya stunting, telah menjadi suatu hal yang sangat penting. Survei Status Gizi Balita Indonesia (SSGBI) tahun 2019 telah memberikan peringatan dengan melonjaknya prevalensi stunting hingga mencapai angka 27,67%. Selain itu, Kabupaten Siak telah mengalami lonjakan kasus stunting sebesar 3% yang mengkhawatirkan dibandingkan tahun 2021 ketika angkanya mencapai 19%, dan kemudian meningkat menjadi 22% pada tahun 2022. Proyek ini dirancang secara strategis untuk mengatasi tantangan ini melalui Skrining Anemia dan evaluasi status gizi ibu hamil di Kabupaten Siak khususnya diwilayah kerja Puskesmas Minas. Skrining Anemia dilakukan untuk mengidentifikasi kasus dengan kadar Hb di bawah 11 g/dl, yang merupakan indikator penting anemia terkait kehamilan. Penilaian gizi dinilai dari kebiasaan makan dan asupan minuman sebelum hamil. Pengukuran Lingkar Lengan Atas (LILA), tes Hb, dan pemeriksaan USG dilakukan, mengidentifikasi satu kasus yang memerlukan perhatian medis lanjutan. Metode pelaksanaan kegiatan pengabdian ini berupa diskusi dengan kader kemudian dilakukan penyuluhan mengenai stunting terhadap kader. Ditemukan 1 kasus yang perlu penanganan lebih lanjut ke fasilitas kesehatan lanjutan. Dapat disimpulkan ada perbedaan yang signifikan pengetahuan kader sebelum dan sesudah edukasi tentang anemia dan skrining gizi pada ibu hamil.In Indonesia, addressing malnutrition, especially stunting, has become urgency. The Indonesian Child Nutrition Status Survey (SSGBI) in 2019 highlighted a surge in stunting prevalence to 27.67%. Siak Regency witnessed a concerning rise in stunting cases from 19% in 2021 to 22% in 2022. This project aims to tackle these issues through anemia screening and evaluating the nutritional status of pregnant women at Puskesmas Minas. Puskesmas Minas employs Anemia Screening to identify cases with Hb levels below 11 g/dl, a crucial indicator of pregnancy-related anemia. The method involves anemia screening by assessing Hemoglobin levels and nutritional assessment based on pre-pregnancy eating habits, Upper Arm Circumference (LILA) measurements, Hemoglobin tests, and ultrasound examinations. The method for implementing this study activity is in the form of discussions with cadres and then providing education regarding stunting to cadres. 1 case was found that required further treatment at an advanced health facility. It can be concluded that there is a significant difference in cadres' knowledge before and after education about anemia and nutritional screening for pregnant women
EFEKTIVITAS PENGELOLAAN KEUANGAN DESA MULIA SUBUR KECAMATAN PANGKALAN LESUNG KABUPATEN PELALAWAN TAHUN 2023
Full text linkPenelitian ini bertujuan untuk mengetahui proses pengelolaan keuangan Dana Desa di Desa Mulia Subur Kecamatan Pangkalan Kuras Kabupaten Pelalawan. diperlukan asas Efektivitas dalam pengelolaan keuangan Desa merupakan salah satu dasar bagaimana pelaksanaan dan penyaluran keuangan Desa tersebut dapat teralokasikan dengan baik atau tidak. Kemudian informasi terkait pengelolaan keuangan Desaseharusnya dapat diketahui oleh berbagai pihak karena memang harus bersifat terbuka. Penelitian ini dilakukan bertujuan untuk mengetahui tingkat efektivitas penggunaan keuangan Desa khususnya Dana Desa di Desa Mulia Subur berdasarkan Peraturan Mentri Dalam Negeri Republik Indonesia Nomor 113 Tahun 2014 yang meliputi perencanaan, pelaksanaan,penetausahaan, pelaporan dan pertanggungjawaban dan pengawasan. Penelitian ini menggunakan tipe survey deskriptif dan metode kualitatif. Untuk mencapai tujuan penelitian maka peneliti menggunakan tehnik pengumpulan data yaitu Observasi, wawancara dan dokumentasi. Di dalam penelitian ini menggunakan teori Makmur yang terdapat beberapa indikator penilaian (a) Ketepatan penggunaan sumber daya alam (b)Ketepatan penggunaan waktu yang tersedia (c)Ketepatan peralatan penggunaan peralatan atau perlengkapan (d)Ketepatan penggunaan sumber daya Manusia (e)Ketepatan penggunaan Anggaran. Adapun hasil penelitian ini menunjukkan bahwa dalam pengelolaan keuangan khususnya dana Desa menunjukan sudah cukup baik namun belum cukup efektif sehingga penggunaan anggaran masih belum tepat sasaran.
This research aims to determine the financial management process of Village Funds in Mulia Subur Village, Pangkalan Kuras District, Pelalawan Regency. The principle of effectiveness is needed in managing village finances, which is one of the basics of how the implementation and distribution of village finances can be allocated well or not. Then information related to Village financial management should be known by various parties because it must be open. This research was carried out with the aim of determining the level of effectiveness in the use of Village finances, especially Village Funds in Mulia Subur Village, based on the Regulation of the Minister of Home Affairs of the Republic of Indonesia Number 113 of 2014 which includes planning, implementation, administration, reporting and accountability and supervision. This research uses a descriptive survey type and qualitative methods. To achieve the research objectives, researchers used data collection techniques, namely observation, interviews and documentation. This research uses the Prosperity theory which contains several assessment indicators (a) Accuracy of use of natural resources (b) Accuracy of use of available time (c) Accuracy of equipment or equipment (d) Accuracy of use of human resources (e) Accuracy of use Budget. The results of this research show that in financial management, especially Village funds, it is good enough but not effective enough so that the use of the budget is still not on target