Journal of Tropical Pharmacy and Chemistry
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    317 research outputs found

    Analisis Kandungan Garam Gunung Asal Krayan Kabupaten Nunukan Kalimantan Timur

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    Has been studied composition of mountain salt from Krayan, Nunukan, East Kalimantan. This study aims to determine the composition of the minerals contained in the  mountain salt. Mountain salt is obtained from wells Krayan District residents were further prepared for analysis using a technique using Atomic Absorption Spectrometer (AAS), further by looking at the pattern of X-ray Diffraction (XRD) and Scanning electron microscopic (SEM). Based on the results obtained AAS has identified mineral deposits include: Na, K, Mg, Al, Cu, Zn, Fe, Ba, and Sr. From the results of XRD shows that the main peak of the salt Krayan shows major peaks for NaCl crystals with impurities such as KCl, CaCl2, MgCl2, and AlCl3. SEM observation showed that morphology of Krayan salt have cube shape which is the shape of NaCl crystals with space group Fm3m and lattice parameter (a) 5.620 Ã

    Identifikasi Metabolit Sekunder dan Aktivitas Antibakteri Ekstrak Daun Sungkai (Peronema canescens JACK.) terhadap Beberapa Bakteri Patogen

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    A research which identification of secondary metabolites and antibacterial activity test from methanol exstract of leaf Sungkai (Peronema canencens Jack) to several pathogens bacterial, which aims to identification of secondary methabolites and determine the antibacterial activity from crude methanol extract of leaf Sungkai (P. canencens Jack). against Streptococcus mutans, Salmonella thyposa, Bacillus subtilis and Staphylococcus aureus bacteria. Material test obtained by maceration with methanol, then tested for activity. Minimum Inhibition Concentration (MIC) value extract was determined by liquid dilution and the followed by scratches on solid media method.  Minimum Kill Concentration (KBM) value extracts was determined by agar diffusion method with using paper disks.The results secondary metabolite identify form extracts of leaves P. canencens obtainable derived alkaloid, terpenoids - steroids, flavonoids, and tannin compounds. Methanol extract have the antibacterial activity. Minimum Inhibition Concentration (MIC) value of extract is concentration of 20% for bacteria S. mutans, S.thiposa and S.aureus, while for the B. subtilis is konsentration of 15%. Minimum Kill Concentration (KBM) values exstract at a concentration of 5% effective at killing S. mutans and S. thyposa bacteria, while the concentration of 1% effective to bacteria B.subtilis and S.aureus

    Potensi Tumbuhan Kerokot (Lygodium microphylum) dalam Bidang Kefarmasian

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    Tumbuhan Kerokot (Lygodium microphylum) di Kalimantan Timur masih dianggap sebagai gulma karena pertumbuhannya yang sangat cepat dan meluas kesegala arah pada suatu lahan sehingga mengganggu lahan petani jika tumbuh pada lahan perkebunan/ladang petani. Telah dilakukan skrining beberapa potensi kefarmasian terhadap ekstrak Herba Kerokot (Lygodium microphylum) dan terbukti memliki potensi sebagai antioksidan, penumbuh rambut, larvasida untuk nymuk Culex sp dan Aedes aegypty, dan obat luka. Potensi terbaik dari hasil-hasil penelitian tersebut adalah sebagai penumbuh rambut yang telah dilakukan pada hewan uji

    Garam Gunung Asal Krayan sebagai Zat Aditif untuk Menstabilkan Klorofil Sayuran

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    Garam Gunung Asal Krayan yang terdapat pada wilayah utara pulau Kalimantan dipercaya oleh masyarakat setempat untuk menyembuhkan berbagai macam penyakit seperti darah tinggi, kencing manis, penyakit kulit serta beberapa penyakit lainnya. Sayur yang menggunakan garam gunung terlihat lebih segar atau nampak tidak layu dan kesegarannya tahan lama dibandingkan dengan menggunakan garam biasa. Dilakukan penelitian untuk mengetahui efek garam gunung asal Krayan terhadap stabilitas sayuran dilihat dari perubahan kadar klorofilnya dengan beberapa perlakuan. Klorofil diukur absorbannya dengan menggunakan spektrofotometer pada panjang gelombang 649 nm dan 665 nm. Didapatkan hasil waktu penyimpanan sayuran yang menggunakan garam gunung asal Krayan yang masih mendekati klorofil sayuran segar adalah pada saat selesai pengolahan (0 jam) yaitu sebesar 22,11 ppm. Perubahan warna pada sayuran yang menggunakan garam gunung asal Krayan lebih lambat dibandingkan dengan garam biasa

    Kandungan Bahan Kering Tanpa Lemak (BKTL) Susu Sapi Perah Friesian Holstein Akibat Pemberian Pakan yang Mengandung Tepung Katu (Sauropus androgynus (L.) Merr) yang Berbeda

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    The purpose of this research was to determine the effect of increasing the provision shrub on milk solid non fat content of Friesian Holstein dairy cattle. Research material used was 9 Friesian Holstein dairy cattle on the second lactation at the sixth month lactation with body weight (BW) of 436 ± 48.67 kg, milk production of 8.86 ± 1.2 liter. Single factor experiment arranged in Complete Random Design with 3 treatments, each replicated for three times, was used in this experiment. The cows were fed with concentrate feed (Crude Protein = 13.42%) added by shrub flour at three levels of 0 % BW (t0), 0.03 % BW (t1), 0.05 % BW (t2), and maize straw as forage at each level of shrub flour in the concentrate. The ratio between concentrate and forage 60%:40%. Obtained data was calculated by ANOVA. Results showed that the average consumption of dry matter feed determined at t0, t1, and t2 were 10.22; 10.70 and 11.63 kg/cow/day (P>0.05), respectively. The average of milk solid non fat of t0, t1 and t2 were 0.672; 0.811 and 0.864 kg/liter (P>0.05), respectively. However shrub flour providing in the concentrate until level of 0.05% BW did not increase milk solid non fat of Friesian Holstein dairy cattle milk solid non fat

    Beberapa Tumbuhan Obat Asal Kalimantan Timur sebagai Sumber Saponin Potensial

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    Saponin is a class of natural compounds that have activity that is strongly associated with utilization in pharmacy. Exploration has been carried out against a number of secondary metabolite content of medicinal plants in East Kalimantan and some of them found to contain saponins. Plants were found to contain saponins and are considered potential Kokang leaf (Lepisanthes amoena), Kesumbakeling leaf (Bixa orellana, L), Belimbing Wuluh leaf (Averrhoa bilimbi L.), Sugi Gadjah leaf (Hyptis capitata), Karamunting leaf (Melastoma malabathricum L), Cempedak bark (Artocarpus champeden), Wijaya Kusuma leaf (Epiphyllum oxipetalum), Langsat seeds (Lansium domesticum), ekor kucing leaf (Acalypha hispida), Kelor bark (Moringa oleifera), Jarong leaf (Stachytarpheta mutabilis), Miana leaf (Coleus atropureus), Jengger Ayam leaf (Celosia cristata), and fruit of Libo (Ficus vargelata)

    Formulasi Pasta Gigi Berbahan Aktif Ekstrak Daun Sirih Hitam sebagai Antimikroba Penyebab Radang Gusi (Gingivitis) dan Gigi Berlubang (Caries)

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    This study aims to obtain a formula toothpaste preparations with active ingredient is extracts of black betel leaf which effectively kills microbes cause inflammation of the gums (gingivitis) and tooth perforated (caries). The active ingredient is obtained by performing maceration followed by fractionation of the extract. Test of antimicrobial activity against microorganisms Streptococcus mutans & Candida albicans using the diffusion method, which will get an effective concentration to be used for toothpaste formulations with active ingredient is black betel leaf. Then continued with the test and evaluation of the effectiveness of the final dosage form of toothpaste preparations. Obtained from the test concentration of 20% n-hexane extract fraction of black betel leaf have the greatest antimicrobial power against Streptococcus mutans and Candida albicans. And after optimization of the base, obtained the good mass forming of toothpaste with base PGA (Pulvis Gummi Arabica) at concentration of 30%

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