Winona State University

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    17246 research outputs found

    Teacher\u27s Contract 1877, School District Nine, Winona County, Minnesota

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    1903 teacher\u27s contract between Annie W. Robb and School District Number Nine of Winona County, Minnesotahttps://openriver.winona.edu/wsuphotographs-minnesotareflections/1302/thumbnail.jp

    Winonan

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    This issue of the Winonan, the Winona State University student newspaper, was published on March 5, 2025. The PDF file includes embedded date correction for the publication year, 2025.https://openriver.winona.edu/thewinonan2020s/1049/thumbnail.jp

    Microbial Contamination in Cosmetic Products: Identification, Characterization and Safety Implications

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    The FDA has reported that microbes can get into cosmetic products through contaminated raw materials or water, poor packaging or storage conditions, ineffective preservation system and poor manufacturing conditions. The various bacteria or fungi found within these cosmetic products pose potential health risks. The FDA does not require approval before cosmetic/hygiene products go on the market only that they must be properly labeled. This demonstrates the lack of regulation and the importance of bacterial and fungal characterization to ensure product safety and compliance with safety standards. In this study, microbiological techniques were used to identify and analyze bacteria or fungi present in a lotion sample. By performing serial dilutions, plating, staining, and a series of biochemical tests, the study aimed to determine the quantity of bacteria or fungi present, morphology, metabolic characteristics, and antibiotic susceptibility. The findings provide insight into the microbial composition of the lotion sample, emphasizing the importance of quality control in cosmetic and personal care products

    An exploration of simple methods for the purification and separation of natural curcuminoids

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    The separation of curcumin from other naturally occurring curcuminoids, such as demethoxycurcumin and bisdemethoxycurcumin, presents significant challenges due to their similar chemical structures. Conventional methods like column chromatography are energetically and environmentally costly, requiring large amounts of solvents and extended processing times. Alternatively, preparatory scale high-performance liquid chromatography (HPLC) offers high precision but necessitates expensive equipment, making it less accessible for routine laboratory use. This research explores simpler and more sustainable approaches to purify curcumin, aiming to reduce both the environmental impact and the financial burden associated with traditional separation techniques

    Modeling SOD1 Enzyme Mutations: Biochemistry II Lab Class Project

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    Superoxide Dismutase 1 (SOD1) is an enzyme that catalyzes the detoxification of reactive oxygen species that cause damage to the body. Mutations of this protein can cause diseases, such as Amyotrophic Lateral Sclerosis (ALS). The structures of the SOD1 wild type and two of its deleterious mutations (A4V and L126*) were digitally modeled using the AI program AlphaFold3. Although a literature structure exists for A4V, no experimental structure data has been collected for L126*. The wild type and A4V structures were virtually identical, whereas the wild type and L126* structures had quite different features, with the mutant being smaller and having more protrusions. The wild type and L126* structures had molecular surface models created, which were then 3D printed. Protein structure visualization using AI software modeling and 3D printing can be used to show how protein mutations can cause structural changes, which in turn alter protein function, causing disease

    WSU President Ken Janz Welcome to WSU\u27s Research and Creative Achievement Day - Remarks

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    Dr. Ken Janz will present welcome poster presenters and the community to the 2025 Research & Creative Achievement Day

    CE 660 Syllabus: Counseling Theory and Practice

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    This course exposes students to theories of personality development and change, theories of counseling, and counseling techniques. Students practice application of counseling theories in a laboratory setting with simulated situations. Students are encouraged to identify and develop a tentative theory of personality as it relates to an effective counseling approach. A strong emphasis is placed on the ethical standards of the counseling profession and on multicultural issues

    Comparing FastBridge Reading Assessment Scores: Reading Interventionist vs. Lexia PowerUp for Sixth-Grade Students

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    This study investigates the differences in FastBridge reading assessment scores among sixth-grade students at a middle school in Southeast Minnesota. A sample of 266 sixth graders participated in the technology-based intervention program, Lexia PowerUp, while 35 students received additional support from a reading interventionist using the UFLI (University of Florida Literacy Initiative) Foundations curriculum. Employing a quantitative, non-experimental post hoc analysis, the research revealed that both Lexia PowerUp and UFLI: Foundations enhanced FastBridge AUTOreading scores; however, FastBridge aReading scores showed no significant changes for either program. Notably, students utilizing Lexia PowerUp consistently improved throughout the year, whereas those in the UFLI program demonstrated the most substantial gains from winter to spring. The findings affirm the effectiveness of technology-based interventions in literacy education, while also highlighting the critical need for qualified reading interventionists. This study contributes to the existing literature on the relationship between educational interventions and reading proficiency, advocating for a multifaceted approach to support struggling readers

    Winonan

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    This issue of the Winonan, the Winona State University student newspaper, was published on April 9, 2025.https://openriver.winona.edu/thewinonan2020s/1050/thumbnail.jp

    Balance Interventions vs. Strength Exercises for Chronic Ankle Instability

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    Clinical Scenario: Recurrent ankle sprains and instability are common concerns, especially among physically active individuals. Without proper intervention and management, patients can develop chronic ankle instability (CAI), which is a condition of recurring “giving way” of the ankle that can negatively affect function and quality of life. Research currently suggests that CAI can be managed through rehabilitation. However, it is unclear what the most beneficial intervention is for reducing CAI symptoms and regaining function. The purpose of this critical appraisal is to investigate the difference between the impact of balance-based and strength-based interventions on the range of motion of patients with CAI. Clinical Question: In patients with Chronic Ankle Instability what is the effect of balance interventions compared to strength-based exercises on increasing ROM? Search Strategy and Evidence Quality: The database, PubMed, was used to find randomized control trials (RCT). The inclusion criteria were CAI, balance, strength, and physical activity. Elite and collegiate athletes were excluded. The search terms utilized were: CAI, ankle balance exercises, ankle strength exercises, improvement, ankle rehabilitation, and recurrent ankle sprains, (ROM). Seven qualifying scholarly articles were identified. An evidence quality assessment resulted in PEDro scores ranging between 4/10-9/10, Oxford Score was 2 for all the studies. Results: The existing research shows consistent findings for increases in dorsiflexion and eversion with balance interventions. The use of strength interventions showed consistent increases in dorsiflexion, plantarflexion, and eversion. The research strengths are indicated by consistent measures of increased range of motion and function. The limitations were small subject pools, lack of standardized exercise programs, and limited long-term studies. Overall, the results of the existing literature show ankle ROM increases from both balance and strength interventions. Clinical Bottom Line: Both interventions produce increases in dorsiflexion and eversion range of motion, with strength interventions also increasing plantarflexion of patients with CAI. To answer the proposed clinical question, it is suggested that balance interventions may produce more meaningful improvements, however, the use of a combination of intervention strategies is recommended to improve the range of motion, and therefore, the overall function of patients with CAI. (SORT score); A. Implications: The findings of this critical appraisal may have practical implications for implementing a combination of interventions effective management strategies for symptoms and functional improvement for CAI. Educational implications suggest the consideration of the effects of using combined intervention strategies to maximize rehabilitative outcomes and patient quality of life. Further investigation is recommended to determine broader population and long-term outcomes

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