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Chronic Cannabis Use and the Effects on General Anesthesia
No full textA poster presentation to educate people on chronic cannabis use, how cannabis effects patients under general anesthesia, and the research gap within cannabis studies. These findings were found by doing literature reviews and interviews with Certified Registered Nurse Anesthetists. The poster will also include a survey done when educating Family Nurse Practitioners used to gather understanding of cannabis use and the effects on general anesthesia
The Impact of Vitamin D on Mental Health in College Students
Full text linkMental illness can impact persons of all ages. A Healthy Minds study revealed that more than 60% of college students met the criteria for at least one mental health condition over the course of a year. Mental health issues such as generalized anxiety disorder (GAD) and major depressive disorder (MDD) have been associated with insufficient dietary vitamin D and sun avoidance amongst college students. Because mental illness is becoming increasingly prevalent in college students, we did a literature search to examine the association of vitamin D and mental health among college students. This topic is relevant as college students\u27 busy schedules and other responsibilities may hinder safe sun exposure and a well-balanced diet, possibly leading to lower vitamin D levels.
Findings from a preliminary literature search revealed that college students had a limited understanding of the importance and the effect of vitamin D on health and well-being. For example, students, in general, do not know the recommended adult daily intake for vitamin D or its benefits. Our public health project focuses on students at the WSU Health Services clinic setting and the surrounding campus area. We aimed to raise university students\u27 awareness about the recommended daily intake of vitamin D, educate them on ways to obtain vitamin D, and highlight the positive effects of vitamin D on mental health. We created an educational brochure containing information about signs of vitamin D deficiency, how vitamin D impacts mental health, where sources of vitamin D can be found, as well as additional resources to view regarding vitamin D. We plan to hand out the brochure in various settings around the Winona State Campus. For example, we will hand out the brochures at WSU Health Services and answer any of the students\u27 questions. Also, the brochure will be emailed to all WSU nursing students including specific groups such as athletes. This is an important intervention to promote knowledge about vitamin D and help our university students to have the information that they need to make good choices about their own health
Synthesis and characterization of cationic PTA complexes with ruthenium
No full text1,3,5-triaza-7-phosphaadamantane (PTA) is a tertiary, cage-like phosphine that is often used to increase the aqueous solubility of transition metal complexes, most notably in the well-studied class of ruthenium-arene PTA (RAPTA) compounds, extensively studied for their antitumoral activity. Increasing solubility and maintaining structure in an aqueous environment are two approaches we are currently pursuing to find more active species. We have prepared novel, cationic PTA complexes with ruthenium-cymene. These have been characterized by NMR, MS, IR, and UV-vis spectroscopies. Additionally, preliminary analysis of their biological activities against common bacteria have been conducted
Assessing the Bioactivity of Ruthenium β-Diketonate Complexes Through Kirby-Bauer Disk Diffusion and Monitored Real-Time Growth Assay
No full textRuthenium(II) β-diketonate complexes present a novel approach for combating a wide range of pathogens. While similar complexes have shown some anticancer properties, their use as an antimicrobial has gone mostly unexplored. This study seeks to investigate the potential antimicrobial properties of a variety of these complexes including some curcuminoid-substituted complexes. Curcuminoids were specifically chosen as a ligand as they are analogues of curcumin, found in turmeric, which has shown some antimicrobial activity. Using Kirby-Bauer disk diffusion assays, we screened these compounds for activity against Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus. Compounds exhibiting antimicrobial activity were subsequently subjected to a monitored real-time growth assay to further evaluate their bioactivity. To date, one candidate has shown promising results against E. coli and S. aureus in preliminary screenings, with additional compounds being tested. As antibiotic resistance continues to rise, identifying new therapeutic agents becomes increasingly urgent. The results from this investigation may serve as a foundation for further in vitro and in vivo studies, advancing the development of these compounds as potential drug candidates
Advances in the attempted first ever synthesis of ebtellur
No full textEbselen, first synthesized in 1924, was used to mimic the antioxidant activity of the glutathione peroxidase enzyme which was being used to relieve oxidative stress. Ebselen was found to be an effective anti-inflammatory and antioxidant agent, as well as being cytotoxic to yeast, fungi, and bacteria. In 2020, ebselen underwent several clinical trials where it proved to be highly active in inhibiting the SARS-CoV-2 main protease causing Covid-19. Due to these promising results, ebselen underwent evaluation for its ability to combat the SARS-CoV-2 infection. In these trials ebselen was observed to be highly unselective, thus it bound to a minimum of 462 different proteins that are apparent in cells. This is a driving factor for the research of ebselen derivatives. Despite the promising results of ebselen, the heavier chalcogen version with tellurium, ebtellur, has never been reported. As such potential bioactivities are currently purely speculative. Computational studies performed demonstrate ebtellur\u27s similar reactivity behavior to ebselen (with respect to peroxynitrite degradation) though exact bioactivities can only be determined experimentally, thus requiring a successful synthesis and isolation of ebtellur. The goal of this project was to first perform the first ever synthesis of ebtellur by trialing multiple routes successfully used to produce ebselen and derivatives thereof
The Economic Impact of the Emerald Ash Borer in Inver Grove Heights MN
Full text linkEmerald Ash Borer (EAB) is an insect that bores under the ash tree\u27s bark. This effectively kills the tree by girdling its cambium. In this analysis of EAB, we looked at the financial effect it had on Inver Grove Heights, Minnesota. Expert Tree Service removed most of their ash trees and provided us with data to help calculate how much it cost. Brian Swoboda, the head forester for Inver Grove Heights, provided us with all of the information about their plan to reforest.
In total, for the years 2022 and 2023, the removals done by Expert Tree Service cost 418,500 USD. Jobs with more trees cost significantly more, with a P-value of 0.00000194 and an F-value of 95.66.
Ash trees were planted after the mass death of elm trees. Inver Grove is learning from past mistakes and is now planting a variety of unrelated species, including White Oak, Honey Locust, Northern Catalpa, and Swamp White Oak
CE 630 Syllabus: Counseling Children and Adolescents
Full text linkIn this course, students will learn the history, theory, and practice of counseling children and adolescents and its defining principles. Topics will include thoughts and behavior change, relationships, family systems, creative arts in counseling, and the ethics and legal foundations when working with children. Common presenting concerns and counseling interventions to respond to them effectively will also be introduced. Ethical and multicultural considerations will be incorporated throughout the course
CE 534 Syllabus: Multiculturalism and Diversity
Full text linkGood standing with WSU/College/CED, and graduate status, no specific undergraduate/graduate course pre-requisites are required for admission to the course
CE 650 Syllabus: Diagnosis and Psychopathology of Adults - Winona
Full text linkThe purpose of this course is to introduce students to the etiology and classification of mental disorders as defined by the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition Text Revision (DSM-5 TR). Students will learn to utilize diagnostic information to conduct diagnostic interviews, conceptualize the presenting problem, and write diagnostic assessments in order to facilitate case management, treatment plan development, and therapeutic interventions with people seeking/receiving mental health counseling services. The instructional methodology will include lectures, case studies presented in class, diagnostic activities using dyadic and small group activities, and other instructional modalities designed to facilitate the learning process