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Consideration of Thyroid Weight Estimation Methods Using Thyroid Scintigraphy
Get PDFバセドウ病の RI 内用療法では甲状腺重量の推定が必要である．甲状腺重量の測定方法として，従来から甲状腺シンチグラフィを用いた Allen-Goodwin 法，大久保法，Himanka 法など 3 つの方法が知られている．我々は，これら 3 つの方法に加えて，甲状腺の側面撮像を行い，楕円体の体積を求める公式に代入した式（楕円法）を入れた 4 つの方法で既知のシリンジ体積を対象として，甲状腺の推定重量の至適 cut off 値を求めた．また甲状腺 SPECT/CT 法で求めた甲状腺の推定重量との比較検討を行った．
解析の結果，Himanka 法での至適 cut off 値は，Allen-Goodwin 法および大久保法よりも変動が少なかった．また楕円法による至適 cut off 値は，5 mL を除き，30% となり一定であった．甲状腺シンチグラフィによる重量推定では，至適 cut off 値を選定できれば，CT による被ばくを患者に与えること無く SPECT/CT 法と同様に甲状腺の重量を推定することが可能である．In radioiodine therapy for Graves’ disease, it is necessary to estimate the thyroid weight. Four methods, including the Allen-Goodwin, Ohkubo, and Himanka methods, which use thyroid scintigraphy, and a method that involves taking a lateral view of the thyroid and using an equation that substitutes the elliptical body’s volume （elliptical method），were used to determine the optimal cut-off value for estimating the known syringe volume as the estimated weight. A comparison was made between the estimated weight obtained using SPECT/CT and that obtained using each methods. As a result, the optimal cutoff value in the Himanka method had less variation than the Allen-Goodwin and Ohkubo methods. The optimal cut-off value in the elliptical method was constant at 30 % except for 5 ml. If an appropriate cut-off value is selected for estimating weight based on thyroid scintigraphy, weight estimation can be performed similarly to SPECT/CT and additional radiation exposure from CT.journal articl
Development of a young rat hyperkalemia model with decreased renal excretion of potassium
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Neuromuscular electrical stimulation during hemodialysis suppresses postprandial hyperglycemia in patients with end-stage diabetic kidney disease: a crossover controlled trial
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An exploratory study on the development of drug-induced renal hyperpotassemia in general anesthetized rats
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