Universitas Prima Indonesia: Open Journal Systems
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Differences in nutritional status of exclusively breastfed and non-exclusively breastfed infants aged 0-6 months in Kutambaru Village, Munte Subdistrict
No full textNutritional status in children under five remains a critical public health issue in Indonesia, characterized by high rates of stunting (21.6%) and wasting (7.9% in North Sumatra). Exclusive breastfeeding (EBF) for the first six months is vital for optimal growth, but compliance is low. This study aimed to analyze the determinants of nutritional status, focusing on the differences between infants aged 0-6 months receiving exclusive breastfeeding and those receiving breastfeeding plus early complementary feeding (MPASI). This research employed a comparative analytical design with a total sampling of 40 mothers and their infants (0-6 months) in Kutambaru Village, Munte Subdistrict. The independent variables were breastfeeding status (exclusive vs. non-exclusive) and complementary feeding status. The dependent variable was infant nutritional status (weight-for-length). Data were analyzed using the Chi-Square test. The results demonstrated a statistically significant association between exclusive breastfeeding and infant nutritional status (p = 0.019). Infants who received EBF were significantly more likely to have an optimal nutritional status. Complementary feeding also showed a significant association (p = 0.033). In conclusion, exclusive breastfeeding is the dominant factor significantly associated with optimal nutritional status in infants 0-6 months. Strengthening interventions to promote EBF is critical to prevent malnutrition
The association between smoking behaviour and degenerative diseases
No full textDegenerative diseases represent a leading global cause of death, imposing a substantial health burden, wherein behavioural factors such as smoking are posited to play a significant role. This study aimed to analyse the association between smoking behaviour and the incidence of various degenerative diseases through a systematic literature review. The methodology employed was a systematic literature review, with article searches conducted across Google Scholar, PubMed, and Scopus databases from May to June 2025. Inclusion criteria encompassed full-text articles in Indonesian or English, published between 2020 and 2025, focusing on the association between smoking and degenerative diseases (hypertension, diabetes, stroke, kidney failure, cancer). From 230 identified articles, 15 met the criteria and were analysed. The synthesis of results demonstrated a significant association between smoking behaviour and an increased risk of degenerative diseases. Active smokers exhibited a three-fold higher risk of hypertension (OR=3.445), a twelve-fold higher risk of type 2 diabetes mellitus (OR=12.747), and a greater risk of developing cancer (lung, breast, laryngeal), stroke, and chronic kidney disease (CKD). Exposure to secondhand smoke among passive smokers also increased the risk of breast cancer nearly fourfold (OR=3.778). Underlying mechanisms include oxidative damage, chronic inflammation, endothelial dysfunction, and metabolic dysregulation. It is concluded that smoking is a major modifiable risk factor for degenerative diseases. Strengthening tobacco control policies, intensive health education, and smoking cessation programmes are required as primary prevention strategies
The Effect Of Giving Sambiloto Leaf Extract (Andrographis Paniculata) On Collagenization And Histopathological Picture Of Skin Tissue In The Healing Process Of Dermapen Wounds In White Wistar Male Rats
No full textThis study aims to analyze and test the administration of d extractAndrographis paniculata (Andrographis paniculata) affect growth collagen in the wound healing process of dermapen scars in male Wistar white rats (Rattus norvegicus) and assessing its histopathological features. This study is a true experimental study, using a post-test only control group design. The sample in this study was 24 animals. Preparation of test animals is to increase the weight of mice and make dermapen wounds. Dermapen action is carried out with a needle depth of 2 mm and a wound width of 2 cm. The wound healing process is observed every day for 14 days. This study showed that the group given Andrographis paniculata leaf extract cream with concentrations of 5%, 7%, and 10% had an effect on the healing process of wounds from dermapen in obese white rats (Rattus norvegicus) wistar strain. The treatment group experienced total healing, while the control group given base cream did not. The results of histopathological observations showed that the control group produced very thin collagen growth, while in the treatment given Andrographis paniculata leaf extract with concentrations of 5%, 7%, and 10% the collagen was fully filled and dense. The results of phytochemical tests showed that Andrographis paniculata leaf extract contained secondary metabolites in the form of flavonoids, saponins, tannins, and triterpenoids. These findings indicate that Andrographis paniculata extract increases collagenization and accelerates wound healing, making it a promising treatment for wounds caused by dermapen
Evaluation of Hospital Management Information System (HMIS) Implementation Using HOT-Fit Method in Rasyida Kidney Special Hospital Medan
No full textImplementation of HMIS in Rasyida Kidney Special Hospital Medan has been used since 2018 to support services in improvement, effectiveness, and work efficiency. However, there are problems such as unstable networks, sometimes errors when operating, and not being integrated directly with the BPJS system, resulting in delays in service from patient registration and data input to the patient discharge process. Evaluation is needed to measure successful implementation using the HOT-Fit (Human, Organization, and Technology Fit) method. The aim is to assess factors that positively influence HMIS's successful implementation by completing Google forms (56 respondents) and in-depth interviews (6 respondents). The mixed method is used with concurrent embedded strategy and PLS-SEM with SmartPLS v.4.1.0.6 to analyze. Results showed that user satisfaction has a 79.9% influence, showing that independent variables affect user satisfaction. The higher user satisfaction, the greater HMIS's use. Users have felt the ease of the system, despite an unstable network, frequent errors, and inadequate computer specifications. Increasing the bandwidth, initially 50mbps to 100mbps, so the network is stable, error problems can be overcome, and increasing computer specifications to run the application correctly if an update is necessary
Comparison Between TAM and HOT-Fit Methods in Evaluating the Implementation of SIMRS at Bhayangkara TK II Mas Kadiran Hospital Medan
No full textBackground: Hospital Information System (SIMRS) is a system that includes data collection, data processing, information presentation, data analysis, and information inference needed to support various operational activities in the hospital. Methods: The research used involved two approaches: outer model and inner model. The outer model was used to test validity and reliability with AVE, discriminant validity, Cronbach alpha, and composite reliabilities. The inner model was tested using R Square and hypothesis testing. Results: The results of research based on the HOT-Fit method show that Human factors have a significant relationship to Benefits, Organization, and Technology. In addition, organizational factors also have a significant relationship with benefits and technology. Statistical tests show that Human -> Benefits, Human -> Organization, Human -> Technology, Organization -> Benefits, and Organization -> Technology (p-value = 0.000). Meanwhile, based on the TAM method, it shows that the usefulness factor has a significant relationship to Actual Use, Behavioral Interest, and Attitude. In addition, the Ease factor also has a significant relationship to Usability and Attitude. The Behavioral Interest factor has a significant relationship to Actual Use, and the Attitude factor has a significant relationship to Behavioral Interest. Statistical tests show Usability -> Actual Use, Usability -> Behavioral Interest, Usability -> Attitude, Convenience -> Usability, Convenience -> Attitude, Behavioral Interest -> Actual Use, and Attitude -> Behavioral Interest (p-value = 0.000). Conclusion: The results of this study indicate that human and organizational factors have a significant effect on technology. In addition, Human factors affect Organization and Benefits, while Organization affects Benefits. Furthermore, usefulness affects attitude, usefulness, interest, and actual use, while convenience affects attitude and usefulness. Attitude affects Interest, and Interest affects Actual Use
The Effect of Pagoda Flower Extract (Clerodendrum Paniculatum L) on Pancreatic Function and Histopathological Features of the Pancreas of Male Wistar White Rats Infected with Leptospira Bacteria
No full textThis study was conducted to test the effect of pagoda flower extract (Clerodendrum paniculatum L.) on pancreatic function and histopathological picture of the pancreas of male Wistar white rats infected with Leptospira interrogans bacteria. Based on the difference in the average lipase levels of treatment group 3, namely rats infected with bacteria and given pagoda flowers at a dose of 200mg/KgBW, had the greatest decrease in lipase levels and approached the control group. P3 group after being infected with bacteria amylase- lipase level 68.45U/L- 42.06U/L and after being given pagoda flower extract with a dose of 200mg/KgBB, the amylase-lipase level became 58.75U/L-22.71U/L. There was no necrosis for the histopathological picture of treatment group 3 (P3). However, there was still a little leukocyte infiltration in the pancreatic cells, so this treatment group got a score of 0 without necrosis of pancreatic cells. Thus, it can be concluded that pagoda flower extract affects the pancreatic function of rats infected with leptospira bacteria. The Kolmogorov-Smirnov data analysis p>0.05 is 0.200, so the data is usually distributed
The Effect of Giving Salak Fruit Skin Extract (Salacca Zalacca) on Liver Function and Histopathology of the Liver of Male Wistar White Rats with Diabetes Mellitus
No full textThis study was conducted to test the effect of salak fruit skin extract (Salacca zalaca) on liver function and histopathological features of the liver of male white rats with diabetes mellitus. This study used 24 Wistar rats as experimental animals, divided into 4 groups, namely the control group and treatment (P1, P2, P3) with different treatments. The results of phytochemical testing of salak fruit skin extract contained secondary metabolites such as saponins, tannins, flavonoids, alkaloids, and steroids. On the 14th day of observation, the results showed that administering salak fruit skin extract (Salacca alpaca) at 600 mg/kg BW effectively improved liver function in white rats (Rattus norvegicus) with diabetes mellitus. This improvement can be seen through the SGOT and SGPT levels and the rat liver's histological structure, which is close to the expected results. The data analysis test on the normality test using Kolmogorov Smirnov showed that the significance results in the SGOT examination were 0.677> 0.05 and SGPT 0.551> 0.05, so the data was normally distributed. The homogeneity test results for the variables of group P0, group P1, P2, and P3 were homogeneous
The Effect Of Liquidity, Capital Structure, And Dividend Policy On Company Value With Profitability As An Intervening Variable In The Consumer Industry Sector Period 2019-2023
No full textThis study analyzes the effect of liquidity, capital structure, and dividend policy on firm value with profitability as an intervening variable in the consumer industry sector for the period 2019-2023. This study uses a quantitative approach with the Structural Equation Modeling-Partial Least Squares (SEM-PLS) method. The data used are the annual financial reports of 18 consumer industry sector companies listed on the Indonesia Stock Exchange during the study period. The results of the study indicate that capital structureand profitability directly have a significant effect on firm value, dividend policy shows a significant effect on Profitability, capital structure has a significant effect on firm value, while liquidation and dividend policy do not affect firm value, while liquidation does not significantly affect profitability, capital structure does not affect profitability. Profitability is proven to act as an intervening variable in the relationship between liquidation, capital structure, and dividend policy do not affect firm value through profitability, This study provides practical implications for company management to optimize capital structure to increase firm value through profitability. In addition, the results of this study can also be a consideration for investors in evaluating investment opportunities in the consumer industry sector
Embarkation Haji Dormitory Utilization Model For the Empowerment of Local Communities
No full textThe utilization model of the Hajj embarkation dormitory has significant potential for empowering local communities and increasing non-tax state revenue. However, its current utilization remains suboptimal due to limitations in facilities, management standards, lack of innovation, and minimal involvement of local business actors. This study aims to analyze the utilization model of Hajj dormitories equivalent to star-rated hotels to enhance the welfare of the surrounding communities. The research employs a mixed-method approach, incorporating qualitative and quantitative methods through interviews, field observations, and data analysis. The findings indicate that optimizing Hajj dormitories can be achieved by improving product quality, service standards, and management in accordance with SNI-ISO 9001. Furthermore, Hajj dormitories can be repurposed for various functions, such as public accommodations, training centers, spiritual tourism, and event venues. Involving local communities in the management of Hajj dormitories also contributes to economic growth by creating employment and business opportunities. With a more strategic management model, Hajj embarkation dormitories can be utilized productively throughout the year, beyond the Hajj season
The Effect of Return on Assets (ROA), Earning Per Share (EPS), Net Profit Margin (NPM), Debt to Equity Ratio (DER), Price to Book Value (PBV) on Stock Returns Study Case: Hospital Companies Listed On The Indonesian Stock Exchange 2018-2022
No full textThe purpose of this study was to obtain empirical evidence and analyze the influence of the variable Effect of Return On Asset, Earning Per Share, Net Profit Margin, Debt To Equity Ratio, Price to Book Value on Stock Returns (Empirical Study on hospital companies listed on the Indonesia Stock Exchange in 2018-2022). This type of research is quantitative research. all hospital companies listed on the IDX for the period 2018-2022, totaling 33. The sample used in this study was 8 companies. The type of data used in this study is secondary data sourced from the company's Annual Report. The data analysis technique uses descriptive analysis and multiple linear regression analysis analysis. Based on the results of the study, it was found that the variable Return On Asset has a significant effect on Stock Returns, Earning Per Share has no significant effect on Stock Returns, Net Profit Margin has no significant effect on Stock Returns, Debt To Equity Ratio has no significant effect on Stock Returns, Price to Book Value has a significant effect on stock returns. and Simultaneously Return On Asset, Earning Per Share, Net Profit Margin, Debt to Equity Ratio, Price to Book Value simultaneously have a significant effect on Stock Returns in Hospital companies listed on the IDX for the period 2018-2022