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Relay Coordination in Distributed Power System Network Using Renewable Energy
Get PDFThe integration of renewable energy sources into power distribution networks presents significant challenges for relay coordination, essential for protecting the network from faults and ensuring reliable operation. This paper provides an in-depth analysis of relay coordination principles under fault conditions in a distributed power system using ETAP software. Key analyses, including load flow, short circuit, and fault analysis, were conducted to evaluate the reliability of the developed model. Utilising the Newton-Raphson algorithm, the ETAP software adjusts relay settings in real-time to ensure optimal performance. The study's findings demonstrate the model's effectiveness in maintaining network stability and reliability amidst the dynamic nature of renewable energy sources, highlighting the critical importance of advanced relay coordination strategies in modern power systems
Analysis of Power System Harmonic Effects Based on Data Features and Gene Expression Programming
Get PDFIn order to quantitatively recognize the harmonic impacts of harmonic source users at the common connection point (PCC), a method to calculate the system harmonic impedance and quantify the harmonic impacts by using gene expression programming to analyses data features was proposed in this paper. Firstly, the harmonic voltage and current data satisfying the analysis conditions were selected by using the time series segmentation method. The system harmonic impedance phase angle was obtained by using the characteristic of zero covariance of independent random variables, and then the harmonic phase angle was implanted into the existing data correlation analysis model. When the user harmonic current fluctuated, the accurate system harmonic impedance module was calculated by the user harmonic current fluctuation. When the user’s harmonic current was stable, the harmonic impacts was quantified by the fluctuation of system harmonic voltage. In this paper, the user harmonic impedance was also given in thoughts in the entire process, which reduced the error caused by ignoring the user harmonic impedance in the traditional method. Some potential Evolutionary Algorithm based solutions which could be further applied in this domain was also reviewed. As a particular novelty of this work, the possibility and feasibility of employing gene expression programming into the conventional data correlation analysis work in power system. Simulation analysis and practical engineering examples showed that this method can effectively suppress the influence of system harmonic change and user harmonic impedance compared with the existing methods and obtained more accurate harmonic responsibility division results.10.13039/501100010880-State Grid Corporation of China, grant number 511904230005
Investigation of the effects of the Small Linear Peptide KiR-SLiM in the assembly and function of Protein Phosphatase 1 (PP1) holoenzyme complexes
No full textThis thesis was submitted for the award of Doctor of Philosophy and was awarded by Brunel University LondonProtein phosphatase 1 (PP1) is an essential phosphatase responsible for many de-phosphorylating events in cells throughout the cell cycle. PP1 functions as holoenzyme complex consisting of its catalytic subunit and regulatory subunits determining its substrate specificity by recruiting PP1 to de-phosphorylation targets. The holoenzyme complex formation is mediated by several small linear motifs (SLiMs) within the regulatory subunit. A specific SLiM termed KiR-SLiM (Ki-67-Repo-Man SLiM) was discovered which is only used by Cdca2 and Ki-67 to bind to PP1. In some cancers, protein levels of holoenzyme complex proteins are dysregulated leading to aberrant dephosphorylation and uncontrolled cell proliferation. Despite this, the development of controlled PP1 inhibition has proven challenging. A molecular understanding of PP1 holoenzyme formation, recruitment and substrate specificity is still quite patchy needing further investigation to discover specific PP1 holoenzyme inhibitors for treating specifically dysfunctional PP1 holoenzyme complexes in cancer. We have shown that a KiR-SLiM peptidomimetic is sufficient to recruit PP1cγ to an artificially created location in the chromatin. We discovered that KiR-SLiM localises to the nucleoli which can be impaired by removing PP1, depleting RRP1B or Ki-67 or increasing the size of KiR-SLiM. We have shown the stable binding of PP1cγ and PP1cβ to KiR-SLiM by pull-down in vivo and identified the interactome of KiR-SLiM. Furthermore, we have shown that the overexpression of KiR-SLiM leads to a G1-phase arrest in HeLa cells, however the mechanism is still elusive. We established a reliable gene editing method to endogenously label PP1cβ generating a stable HCT116:TETONOSTR1 cell line; these ground-breaking tools allow the in vivo investigation of endogenous PP1cβ. This work gives an important insight into the molecular effects of KiR-SLiM as binding motif; the ability of KiR-SLiM to bind PP1 in vivo leading to cell cycle arrest could pave the way to use interfering peptides to modulate dysfunctional PP1 activity in cells
Radcliffe-Brown: Journeys through colonial worlds, 1881-1955
No full textAlfred Radcliffe-Brown (1881-1995) is widely renowned as a founder of modern social anthropology. This biography challenges popular stereotypes of him as a misplaced positivist and colonial conservative. It shows Radcliffe-Brown to be a thoroughly cosmopolitan scholar, a committed fieldworker and a sharp critic of colonialism. Radcliffe-Brown engaged strategically with colonial authorities to further the interests of his discipline and invoked scientific credentials to critique central aspects of colonial rule. His struggle for intellectual autonomy and advocacy of a comparative sociological approach speaks to many contemporary concerns
Moving Beyond the Bladder Diary: Does New Technology Now Allow Us to Take Investigation of LUTS Into the Community? ICI-RS 2024
Get PDFData Availability Statement:
The authors have nothing to report.All authors contributed to the debate at ICI-RS 24 that is reported in this paper.Context:
Lower Urinary Tract Symptoms (LUTS) are defined by their distressing effect on patients' day-to-day life. Given the pressures on secondary care resources, LUTS may be overlooked or inadequately assessed and therefore patients may be burdened for an extended period before treatment.
Methods:
In a debate held at the International Consultation on Incontinence Research Society (ICI-RS) meeting in Bristol in June 2024, we considered how new technologies might contribute to an expedited, dignified and effective investigation of LUTS.
Results:
We describe three broad areas where technology has a role to play: streamlining of existing investigations through mobile and miniaturized technology; entirely new investigations made possible by the technology; and advanced analytics to provide better insights from the data available.
Conclusion:
We describe key research questions that will signpost us toward answering the question raised in the title.The authors received no specific funding for this work
Search for long-lived heavy neutrinos in the decays of B mesons produced in proton-proton collisions at √ = 13 TeV
Get PDFA version of the article is available at arXiv:2403.04584v2 [hep-ex] (https://arxiv.org/abs/2403.04584). Comments: Replaced with the published version. Added the journal reference and the DOI. All the figures and tables, including additional supplementary figures, can be found at https://cms-results.web.cern.ch/cms-results/public-results/publications/EXO-22-019 (CMS Public Pages). Report number: CMS-EXO-22-019, CERN-EP-2024-053. Journal reference: JHEP 06 (2024) 183. Submission history: From: The CMS Collaboration: [v1] Thu, 7 Mar 2024 15:29:24 UTC (954 KB); [v2] Tue, 2 Jul 2024 16:53:27 UTC (954 KB).A search for long-lived heavy neutrinos (N) in the decays of B mesons produced in proton-proton collisions at √ = 13 TeV is presented. The data sample corresponds to an integrated luminosity of 41.6 fb⁻¹ collected in 2018 by the CMS experiment at the CERN LHC, using a dedicated data stream that enhances the number of recorded events containing B mesons. The search probes heavy neutrinos with masses in the range 1 N N N is the N proper mean lifetime. Signal events are defined by the signature B → ℓBNX; N → ℓ±π∓, where the leptons ℓB and ℓ can be either a muon or an electron, provided that at least one of them is a muon. The hadronic recoil system, X, is treated inclusively and is not reconstructed. No significant excess of events over the standard model background is observed in any of the ℓ±π∓ invariant mass distributions. Limits at 95% confidence level on the sum of the squares of the mixing amplitudes between heavy and light neutrinos, |VN|², and on cτN are obtained in different mixing scenarios for both Majorana and Dirac-like N particles. The most stringent upper limit |VN|² N = 1.95 GeV for the Majorana case where N mixes exclusively with muon neutrinos. The limits on |VN|² for masses 1 N < 1.7 GeV are the most stringent from a collider experiment to date.SCOAP³
Modelling of damage in composites using smooth particle hydrodynamics method
Get PDFThis paper aims at the development and implementation of an algorithm for the treatment of damage and fracture in smooth particle hydrodynamic (SPH) method, where free surface, crack opening, including its propagation and branching is modelled by weakening the interparticle interactions combined with the visibility criterion. The model is consistent with classical continuum damage mechanics approach, but does not use an effective stress concept. It is a difficult task to model fracture leading to fragmentation in materials subjected to high-strain rates using continuum mechanics. Meshless methods such as SPH are well suited to be applied to fracture mechanics problems, since they are not prone to the problems associated with mesh tangling. The SPH momentum equation can be rearranged and expressed in terms of a particleparticle interaction area. Damage acts to reduce this area, which is ultimately set to zero, indicating material fracture. The first implementation of the model makes use of Cochran-Banner damage parameter evolution and incorporates a multiple bond break criterion for each neighbourhood of particles. This model implementation was verified in simulation of the one-dimensional and three-dimensional flyer plate impact tests, where the results were compared to experimental data. The test showed that the model can recreate the phenomena associated with uniaxial spall to a high degree of accuracy. The model was then applied to orthotropic material formulation, combined with the failure modes typical for composites, and used for simulation of the hard projectile impact on composite target.The project leading to this paper has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 636549 https://doi.org/10.3030/636549
Optimizing Irrigation Systems for Water Efficiency and Groundwater Sustainability in the Coastal Nile Delta
Get PDFData Availability: No data was used for the research described in the article.This study investigates the replacement of traditional surface irrigation methods with modern irrigation systems (MIS) including horizontal sprinkler, central pivot, surface drip, and subsurface drip aimed at improving water efficiency in the Nile Delta, Egypt. The primary objectives were to determine the optimal agricultural area for implementing MIS and to assess the effects of these systems on groundwater quantity and quality in the region. To achieve this, the LINDO software was employed to optimize land allocation for each irrigation method. At the same time, the SEAWAT code was utilized to simulate saltwater intrusion (SWI) in the Nile Delta aquifer. The transition from traditional surface irrigation to MIS resulted in significant water savings, reaching 2.15 × 10^9 m³. However, groundwater modeling indicated a decrease in groundwater levels, leading to an 8 % increase in aquifer salinity due to reduced infiltration of recharge water. These findings underscore the urgent need to revise outdated irrigation practices and enhance water management strategies in the Nile Delta to mitigate salinity issues in coastal aquifers. This research's outcomes are crucial for decision-makers and stakeholders in selecting appropriate irrigation methods, particularly in arid and semi-arid regions, to ensure sustainable water use and agricultural productivity.This study did not receive any funding
Critical Criminology, Special Issue Introduction: Critical Engagements with Gender, Race and Class in Crimmigration Controls
Get PDFIntroduction:
In recent years, the escalation of policing, bordering practices, detention, and deportation has become a common phenomenon around the world. There is an expansion of the crimmigration system (Stumpf, 2006), which has increasingly blurred the boundaries between the immigration and criminal justice spheres
The influence of morphology and the loading-unloading process on discontinuity stress states observed via photoelastic technique and its inspiration to induced seismicity
Get PDFData availability: Data will be made available on request.Stress change in rock mass caused by human activities has the potential to cause the sliding and destruction of faults and joints, resulting in induced seismicity. Laboratory experiments are conducted on a simulated fault with various teeth numbers and undulation angles to uncover the mechanism of stress change-induced seismicity. The potential risk of induced seismicity is explained using three methods: the Mohr-Coulomb failure criterion, localization of stress concentration regions, and visualization of maximum shear stress reduction through photoelasticity. Experimental results indicate that the friction coefficient increases with the undulation angle, and the form of stress change has an unignorable impact on frictional instability. The friction coefficient in the vertical unloading process is slightly lower than that in the loading process and larger than that in the shear unloading process. Loading is the stress change caused by shear displacement under constant normal stiffness conditions and unloading is the process of reducing the stress by controlling the position of the boundary constraints in the corresponding direction. Meanwhile, unloading in the shear direction has both seismic and aseismic features. Although the rapid drop of shear stress at the onset of shear unloading may induce fault instability, the reduction of normal stress and the restoration of displacement prove that unloading in the shear direction may also reduce the risk of fault failure in the subsequent process. In addition, the stress concentration region is mainly distributed perpendicular to the contact surface rather than the entire fault. This research is conducive to promoting the application of photoelasticity in studying induced seismicity and provides a practical method for calculating the energy released during such events. Based on the morphological characteristics and stress states of fault surfaces, the findings can be utilized in engineering practice to assess the risk of induced seismicity under different stress change conditions.National Natural Science Foundation of China (Grant Nos. 42220104007, 41831281); State Key Laboratory for GeoMechanics and Deep Underground Engineering, China University of Mining & Technology (SKLGDUEK2115)
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