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    Genomic Analysis of the Novel Mycobacteriophage Bromden

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    Twenty new mycobacteriophages were isolated from soil samples collected around the state of Michigan and other parts of the United States. All phages were capable of infecting Mycobacterium smegmatis and were isolated through either enrichment or direct plating at 32℃. A variety of plaque morphologies were produced based on size, shape, and clarity; both lytic and temperate phages are represented in this collection. The mycobacteriophage, Bromden, was chosen as one of two phages for complete genome sequencing and comparative genomic analyses. The predominant plaque produced by Bromden after 48 hours at 32℃ is 0.5 mm in diameter, circular, and clear. The genome of Bromden is 70.2 Kb, 58.2% GC, and contains 118 genes. Bromden’s complete genome sequence indicates a relationship to mycobacteriophages of cluster L, and strongest similarity to mycobacteriophage DyoEdafos of subcluster L4, which is the only other member of the L4 subcluster of mycobacteriophages. The two genomes align at only 85% identity over 87% of the shorter Bromden, with the largest difference being an 8.5 kb section found in DyoEdafos but missing in Bromden. This accounts for the difference in their gene numbers, as DyoEdafos has 33 more genes than Bromden. Auto-annotation indicated there are 12 possible tRNA genes in Bromden. The GC content of Bromden (58.2%) is low compared to most other clusters of mycobacteriophages as well as their common host, M. smegmatis (67.4%). The other clusters with relatively low GC content also have few members, suggesting that these phages may more readily infect other bacterial hosts with lower GC content. A detailed analysis of the complete genome sequences and comparison with sequenced mycobacteriophages is the subject of the second semester of the yearlong course and is presented

    Milestone 2018

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    Milestone, the Hope College yearbook, is an annual publication of Hope College. The first yearbook was published in 1905 as a single edition and was titled The Hope College Annual. The yearbooks became an annual publication in 1916, which was also when it was titled Milestone.https://digitalcommons.hope.edu/milestone/1106/thumbnail.jp

    News from Hope College, Volume 50.1: Summer, 2018

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    https://digitalcommons.hope.edu/news_from_hope_college/1248/thumbnail.jp

    The Anchor, Volume 131.14: January 24, 2018

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    The Anchor began in 1887 and was first issued weekly in 1914. Covering national and campus news alike, Hope College’s student-run newspaper has grown over the years to encompass over two-dozen editors, reporters, and staff. For much of The Anchor\u27s history, the latest issue was distributed across campus each Wednesday throughout the academic school year (with few exceptions). In recent years The Anchor moved to monthly print issues and a more frequently updated website. The Anchor is now published in print twice per academic semester. Occasionally, the volume and/or issue numbering is irregular

    The Anchor, Volume 132.03: September 19, 2018

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    The Anchor began in 1887 and was first issued weekly in 1914. Covering national and campus news alike, Hope College’s student-run newspaper has grown over the years to encompass over two-dozen editors, reporters, and staff. For much of The Anchor\u27s history, the latest issue was distributed across campus each Wednesday throughout the academic school year (with few exceptions). In recent years The Anchor moved to monthly print issues and a more frequently updated website. The Anchor is now published in print twice per academic semester. Occasionally, the volume and/or issue numbering is irregular

    The Anchor, Volume 132.09: November 7, 2018

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    The Anchor began in 1887 and was first issued weekly in 1914. Covering national and campus news alike, Hope College’s student-run newspaper has grown over the years to encompass over two-dozen editors, reporters, and staff. For much of The Anchor\u27s history, the latest issue was distributed across campus each Wednesday throughout the academic school year (with few exceptions). In recent years The Anchor moved to monthly print issues and a more frequently updated website. The Anchor is now published in print twice per academic semester. Occasionally, the volume and/or issue numbering is irregular

    Artist Talk. Ethiopian Painting: A Conversation with Daniel Berhanemeskel (Hope 2003)

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    A poster for an artist talk on September 22, 2018, related to the exhibition Living Tradition: Contemporary Ethiopian Christian Art from the Sobania Collection. The exhibition was held September 21–December 15, 2018.https://digitalcommons.hope.edu/kam_poster/1014/thumbnail.jp

    The Anchor, Volume 131.22: April 18, 2018

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    The Anchor began in 1887 and was first issued weekly in 1914. Covering national and campus news alike, Hope College’s student-run newspaper has grown over the years to encompass over two-dozen editors, reporters, and staff. For much of The Anchor\u27s history, the latest issue was distributed across campus each Wednesday throughout the academic school year (with few exceptions). In recent years The Anchor moved to monthly print issues and a more frequently updated website. The Anchor is now published in print twice per academic semester. Occasionally, the volume and/or issue numbering is irregular

    Hope College Abstracts: 17th Annual Celebration of Undergraduate Research and Creative Performance

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    The 17th Annual Celebration of Undergraduate Research and Creative Performance was held on April 13, 2018 in the Richard and Helen DeVos Fieldhouse at Hope College and featured student-faculty collaborative research projects. This program is a record reflective of those projects between the 2017-2018 academic year

    The Joint Archives Quarterly, Volume 28.02: Summer 2018

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