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    The Anchor, Volume 127.17: February 19, 2014

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    The Anchor began in 1887 and was first issued weekly in 1914. Covering national and campus news alike, Hope College’s student-run newspaper has grown over the years to encompass over two-dozen editors, reporters, and staff. For much of The Anchor\u27s history, the latest issue was distributed across campus each Wednesday throughout the academic school year (with few exceptions). In recent years The Anchor moved to monthly print issues and a more frequently updated website. The Anchor is now published in print twice per academic semester. Occasionally, the volume and/or issue numbering is irregular

    News from Hope College, Volume 45.4: April, 2014

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    News from Hope College, Volume 46.1: August, 2014

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    https://digitalcommons.hope.edu/news_from_hope_college/1228/thumbnail.jp

    Más Que el Apoyo Académico: La Educación No Formal, y el Programa Servicio País

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    This investigation aims to analyze the operation and overall results of Servicio País Educación (SPE), an intervention-based program offered to primary, low-resource, municipal schools in Chile. SPE’s involvement in the schools Colegio Juan José Latorre and Escuela Municipal de la Pacífica of Valparaíso served as the primary case studies. Functioning from 2010-2012 as an after-school mentoring program aided by college-aged volunteers, SPE provided a non-formal educational environment for a select group of students coming from especially poor socioeconomic situations. These students often underperformed academically or exhibited behavioral issues in the classroom. The program not only provided individualized academic help, but also practical education in the areas of self-esteem, social skills, and emotional health, in hopes it would serve as support for the harsh situations students faced outside school. Results from this investigation were reached from interviews and an analysis of primary documents revealing the actual implication of the program in the two schools. This information identified that a relationship of trust and communication between the school and program was key in its success and the success of the student participants of SPE. In addition, the academic, social, and behavioral development of student participants could not be fully reached through this single program, but was dependent on various external factors. Finally, this study discovered that the non-formal education methods utilized by SPE in the extracurricular environment of these schools could also be implemented by the teachers to create an engaging learning experience in their own classrooms

    Identification of Trafficking Motifs in the C-terminus of the Cystine/Glutamate Exchanger, System xc-

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    System xc- is a heterodimeric plasma membrane transporter, comprised of the proteins xCT and CD98, which facilitates the stoichiometric exchange of extracellular cystine for intracellular glutamate. System xc- serves to protect the cell from oxidative stress, and brief exposure of cells to oxidative agents leads to an increase in trafficking of xCT to the plasma membrane. However, little is known about the mechanisms which govern the constitutive and regulated trafficking of xCT. In the present study, we sought to identify trafficking motifs within the C-terminus of xCT that are important in regulating the delivery and internalization of xCT from the membrane. We used a mutagenesis approach combined with cell surface biotinylation assays to identify regions of the C-terminus that are involved in the constitutive trafficking of xCT. Specifically, using site-directed mutagenesis, we identified a tyrosine based motif between positions 464 -486 containing the sequence YYLFII that contributes to the constitutive trafficking of xCT to the plasma membrane. In addition, we created three truncation mutants at positions 469, 484, and 496 of xCT, and found that an endocytic motif(s) must also exist between position 469 and 484. While there are no canonical endocytic motifs within this region, there is a putative ubiquitination site. Since we have recently demonstrated that xCT is ubiquitinated in Cos-7 cells and ubiquitination of membrane proteins is known to regulate cell surface expression, we are currently using site-directed mutagenesis to test the hypothesis that ubiquitination of xCT in this region leads to the increased rate of internalization of xCT

    Inter-Rater Reliability of the Vascular Access Assessment and Device Selection (VAADS) Tool

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    Intravenous (IV) access is necessary to deliver medications, fluids, and blood products via venous route. However, staff nurses often do not have adequate education to assure that the appropriate IV-access device is chosen. The purpose of this research is to assess the inter-rater reliability of the Vascular Access Assessment and Device Selection (VAADS) Tool between vascular access team nurses and staff nurses. The tool was developed based on the research literature and Infusion Nurses Society (INS) standards to help nurses select the most appropriate IV-access device, early in a patient’s hospital stay. Benner’s “From Novice to Expert” theory looks at five levels of nursing experience. Using Benner’s theory, the researcher identified the vascular access team nurses as experts in comparison to staff nurses. The study was conducted at a small, midwest community hospital using a prospective, observational design with one venous expert, two staff nurses, and six patients. Cohen’s Kappa coefficient was used to measure the inter-rater reliability. The results showed moderate significance (p-value: 0.006, 0.171) in the rater agreement between the expert and staff nurses. The limited data of this pilot study makes conclusions difficult to draw, but further psychometric testing and staff education is needed. Limitations include that the research was conducted at one small, community hospital which also lacked diversity of participants, and a limited amount of data. Not only does the introduction of the VAADS help in assessment of patients’ vascular access needs, but with this particular study researchers will be able to identify potential education needs of nurses

    Eternity’s Nail of Subjectivity: Subjectivity, Ethics, and God in Kierkegaard and Beauvoir

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    Given the striking similarities between Simone de Beauvoir’s Ethics of Ambiguity and Søren Kierkegaard’s pseudonymously penned Sickness Unto Death, the lack of conversation between the two works is rather surprising. Structural similarities between Sickness and Ethics abound: Kierkegaard and Beauvoir intricately interweave the nature of subjectivity and the claim of ethics in becoming a self throughout these texts. A self is not simply a physical-psychic unity, but a dialectically qualified relation of the conscious corporality of being human for Kierkegaard and Beauvoir. This interdependency between subjectivity and ethics are, furthermore, heightened and clarified through rich practical phenomenologies. Through their dialectics, the nature of true subjectivity is further clarified through the ways one can fail to become a self. In both accounts, one fails to live ethically by refusing to properly relate the paradoxical tension of human existence – being immanent and transcendent, temporal and eternal, material and immaterial. Despite the striking symmetry between Kierkegaard and Beauvoir in terms of their deliberative method, however, critical differences emerge in how they understand the constitution of subjectivity. Where Beauvoir explicates an explicitly and necessarily atheistic system of self and ethics, Kierkegaard maintains that not only ethics—but even the possibility of subjectivity—is dependent upon the work of God. For Beauvoir, then, cultivating the open future of persons constitutes the sole imperative for ethics, while for Kierkegaard ethics is grounded in the divine love command which flows only out of the God-relationship. Upon sketching out the shades of concord between the two, I will argue that the resonance between the two works provide a unique avenue for posing an internal criticism as well as an impossible dilemma for Beauvoir’s schema of becoming a self

    The Effects of Priming Humility on Defensive Reactions Following Criticism of One’s Cherished Values

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    This study examined the role of humility in moderating defensive reactions following criticisms of one’s cherished values. Previous research has found that humility involves an accurate view of oneself and openness to new ideas, contradictory information, and advice (Tangney, 2000; Exline, 2009), as well as an appreciation of how different people and varying perspectives can contribute to the world (Tangney, 2000). We predicted that humility would result in reduced defensiveness when people were confronted with an opposing viewpoint. 124 undergraduates participants wrote essays on a cherished social or cultural issue and were told it would be swapped with another participant. Following the essay, participants were implicitly primed with humble, arrogant or neutral words, using a subliminal priming induction (flashing construct-relevant words on a computer for 20ms). They were then given a fixed essay that was critical of religion and told it was from a fellow participant. Participants were then given fixed negative feedback on their own essay and given the opportunity to rate the fixed essay. Lastly, participants were given the opportunity to administer hot sauce to the fake participant after being told that the critical partner did not like spicy food. We predicted that participants in the humility condition would rate the fixed-essay author more favorably and show less behavioral aggression by administering less hot sauce. Although priming condition did not affect essay ratings, there was a significant effect on the amount of hot sauce administered. Participants primed with humility administered significantly less hot sauce than those in the neutral condition. The arrogant priming did not vary significantly from either condition. It appears that humility may help reduce defensiveness

    Do Unique Mate Preferences Matter? Comparing the Predictive Validity of Individual Versus Consensual Standards for a Romantic Partner

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    Although past research has shown that there is considerable consensus in people’s standards for a long-term romantic partner, most researchers have assumed that people’s individual standards are of utmost importance in predicting their partnering behavior. But is this really the case? Despite evidence that greater correspondence between people’s mate standards and their partner’s characteristics is reliably associated with higher relationship quality, no one has examined the extent to which people’s standards simply reflect a common prototype of a prototypical “good partner”. Accordingly, our research examines (a) the extent to which people’s individual standards reflect a consensual standard prototype, and (b) whether the similarity between a person’s standards and his/her partner’s characteristics predict relationship satisfaction above and beyond the similarity between the “prototypical good partner” and the partner’s characteristics. To test these questions, 339 unmarried individuals were recruited from a variety of academic and nonacademic settings and completed an online questionnaire as well as a nine-month follow-up survey. Our results indicated that people’s individual standards were moderately to strongly correlated with the consensual prototype of a good partner (avg. r=.57). When examining the match between standards and people’s partner characteristics, we found that greater individual standard-partner match and greater prototype standard-partner match both independently predicted greater relationship quality. However, when the two variables were examined simultaneously, the match between people’s individual standards and partner characteristics, but not between their partner’s characteristics and the prototype, predicted their relationship commitment, ambivalence, and marital expectations. Interestingly, relationship satisfaction was simultaneously influenced by both variables – people experienced greater relationship satisfaction to the extent that they had a partner who met their own standards as well as reflected the prototypical “good partner.

    The Effects of Threats to Meaning on Attitudes Toward Evolution

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    Humans have an innate need to make sense of the world and give it meaning (Heine, Proulx, & Vohs, 2006), and do so by creating and defending cultural worldviews (Solomon, Greenberg, & Pyszcynski, 2004). Threats to meaning cause existential anxiety, and to protect ourselves from this existential fear, we reject, eliminate, or avoid threats to our cultural worldviews (Schmeichel & Martens, 2005). In addition, following threats to meaning, we compensate by showing aggression towards those who are dissimilar (Rosenblatt, Greenberg, Solomon, Pyszczynski, & Lyon, 1989). Science and religion are two prominent cultural worldviews that can provide meaning. We predict that following a meaning threat, participants high in religious fundamentalism would report a less favorable attitude toward evolution than those low in religious fundamentalism. Sixty introductory self-identified religious students at Hope College participated in this study. Participants first completed a measure of religious fundamentalism. They were then randomly assigned to complete a writing task based on condition: meaning challenge (writing about life’s lack of meaning), meaning affirmation (writing about how they find meaning in life), or neutral (writing about their plans for next week). Finally, they read an essay that presented mixed evidence about evolution and rated the essay and their views on evolution. Data were analyzed using an ANOVA examining the interaction between religious fundamentalism and priming condition on attitudes toward evolution. We found a significant interaction showing that religious fundamentalists were more critical of evolution when their meaning was challenged. Given that religious fundamentalists have been found to hold negative attitudes toward evolution (Poling & Evans, 2004), meaning threats may enhance these negative attitudes as a way of regaining meaning. These results highlight that individuals bolster different sources of meaning that are aligned with their values

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