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Immunometabolic Dysregulation at the Intersection of Obesity and COVID-19
Get PDFObesity prevails worldwide to an increasing effect. For example, up to 42% of American adults are considered obese. Obese individuals are prone to a variety of complications of metabolic disorders including diabetes mellitus, hypertension, cardiovascular disease, and chronic kidney disease. Recent meta-analyses of clinical studies in patient cohorts in the ongoing coronavirus-disease 2019 (COVID-19) pandemic indicate that the presence of obesity and relevant disorders is linked to a more severe prognosis of COVID-19. Given the significance of obesity in COVID-19 progression, we provide a review of host metabolic and immune responses in the immunometabolic dysregulation exaggerated by obesity and the viral infection that develops into a severe course of COVID-19. Moreover, sequela studies of individuals 6 months after having COVID-19 show a higher risk of metabolic comorbidities including obesity, diabetes, and kidney disease. These collectively implicate an inter-systemic dimension to understanding the association between obesity and COVID-19 and suggest an interdisciplinary intervention for relief of obesity-COVID-19 complications beyond the phase of acute infection
Effect of Volatile Compounds Produced by Selected Bacterial Endophytes in Promoting Plant Growth
Get PDFBacterial endophytes selected for their capability to suppress diverse fungal pathogens in vitro and in greenhouse studies have been shown to promote plant growth. The effect of volatile compounds emitted by selected bacteria on plant growth in Arabidopsis thaliana, tomato (Solanum lycopersicum), sweet pepper (Capsicum annuum), and cucumbers (Cucumis sativus) was evaluated on container-grown plants nested above bacterial cultures, with roots exposed to the volatiles without direct contact between bacterial cells and the plant roots. Significant increases in plant growth were observed in plant height, root length, leaf size, fresh weight, and chlorophyll content in all plants tested. Although diverse chemical compounds may be involved in promoting plant growth, including volatile and nonvolatile compounds, observations in this study have implications for the potential role of the selected bacteria in plant production as biofertilizers and biopesticides
Graduate Catalogue 2019 - 2021
Get PDFhttps://digitalscholarship.tnstate.edu/graduatecatalogues/1006/thumbnail.jp
Visiting Congressman
No full textPresident and Mrs. William J. Hale and Congressman Mitchell of Illinois Assembled on the Front Porch of the President\u27s Home on the Congressman\u27s Visit to Nashville, TN.https://digitalscholarship.tnstate.edu/library-digital-collections/1252/thumbnail.jp
Effect of Varying Wind Intensity, Forward Speed, and Surface Pressure on Storm Surges of Hurricane RitaEffect of Varying Wind Intensity, Forward Speed, and Surface Pressure on Storm Surges of Hurricane Rita
Get PDFHurricane storm surges are influenced by several factors, including wind intensity, surface pressure, forward speed, size, angle of approach, ocean bottom depth and slope, shape and geographical features of the coastline. The relative influence of each factor may be amplified or abated by other factors that are acting at the time of the hurricane’s approach to the land. To understand the individual and combined influence of wind intensity, surface pressure and forward speed, a numerical experiment is conducted using Advanced CIRCulation + Simulating Waves Nearshore (ADCIRC + SWAN) by performing hindcasts of Hurricane Rita storm surges. The wind field generated by Ocean Weather Inc. (OWI) is used as the base meteorological forcing in ADCIRC + SWAN. All parameters are varied by certain percentages from those in the OWI wind field. Simulation results are analyzed for maximum wind intensity, wind vector pattern, minimum surface pressure, forward speed, maximum water elevation, station water elevation time series, and high water marks. The results for different cases are compared against each other, as well as with observed data. Changes in the wind intensity have the greatest impact, followed by the forward speed and surface pressure. The combined effects of the wind intensity and forward speed are noticeably different than their individual effects
