Journal of Evolution and Health (Ancestral Health Society Research)
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Proceedings of the 5th annual symposium of the German Society for Paleo Nutrition held in 2017
We present the scientific abstracts of the 5th Annual Symposium of the German Society for Paleo Nutrition (Deutsche Gesellschaft für Paläoernährung) which took place on September 23rd 2017 in Giessen, Germany.
Besides an overview on existing interventional studies on Paleolithic diets, a focus of this year´s symposium was on secondary plant metabolites: presence, standardization by phytoneering and the role of phytomedicine for prevention and treatment of cancer. Further topics were the role of vitamin-D and omega-3 fatty acids, as well as molecular anthropology and personalized nutrition
Brace yourselves, winter is coming: a pilot study of the effects of brief, infrequent cold water immersion upon body composition in young adult males
Background: The existence of functioning brown adipose tissue (BAT) in adult humans has brought into question the possibility of utilising the BAT mechanism as an obesity tackling strategy. This pilot study examined the effects of a short-term (6wk) cold water immersion (CWI) programme on the body composition of (n=10) healthy male adults. It was hypothesized that the thermal stresses would produce reductions in fat mass (FM) and body fat percentage (BFp) as a result of thermogenic activation of the BAT mechanism. Methods: Using a single arm prospective trial design, participants were subjected to singular acute (18min) cold water exposures (15±1°C) weekly for the duration of the intervention (6wk). Results: Non-significant decreases were observed in FM (-1.55±2.24kg; p = 0.057) and BFp (-1.62±2.46%; p = 0.067), and significant increases in fat free mass (FFM; 1.46±1.68kg; p = 0.023). Conclusions: The results indicate that the intervention could be adopted as a plausible method to exert positive changes to body composition. These findings should stimulate follow up studies to examine the interventions efficacy in a larger more representative sample and examine its feasibility of implementation as a genuine obesity tackling strategy
Dietary Refinement And The Upper Gut Microbiota: The Starting Point For Obesity And Non-Communicable Diseases?
Living High and Healthy: Why Coloradans and Others Who Live at High Altitude Live Longer, and What Flatlanders Can Learn From Them
Bacterial development of resistance to botanical antimicrobials
In recent years, increased numbers of multidrug-resistant strains of bacteria have opportunistically and selectively expanded while the pharmaceutical discovery of new antimicrobial therapies has been lacking to combat this growing threat. Like traditional antibiotics, botanicals have historically been used to treat bacterial infections, but it remains unclear if bacteria may have the capability to develop resistance to these therapeutic botanicals. It is believed that one advantage that may prevent or slow resistance to botanical antimicrobials is the presumed presence of the multiple endogenous substances contained within a plant that may act synergistically to inhibit microbial growth. This study examined the potential of an antimicrobial-sensitive strain of Staphylococcus aureus to develop resistance to five botanical extracts commonly used for antibacterial therapy. Our results demonstrated that S. aureus was able to develop resistance to the botanical antimicrobial extracts at a similar rate and level as standard antibiotics thus questioning the idea of multiple synergistic antimicrobials within a botanical tincture. These results demonstrate the need for proper use of botanical antimicrobial extracts to avoid the development of resistance to botanical-based therapeutics and avoid similar problems currently faced with pharmaceutical antibiotics