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Introduction. Thoughts on the entanglement of the concepts and notions of a nation, nationalism and identity in relation to video games and gaming culture
A critical introduction to the special issue of gamevironments focused on nation, nationalism, identity and video games as well as gaming culture
Interview with Mira Wardhaningsih from StoryTale Studios on the Indonesian Horror Game Pamali
An interview by Kathrin Trattner with Mira Wardhaningsih, Cultural Content Director from StoryTale Studios about the game Pamal
Möglichkeiten und Grenzen der Evaluation von Krebsfrüherkennungsuntersuchungen anhand von Routinedaten der Gesetzlichen Krankenversicherung in Deutschland
In Germany, in 2014, about 223,000 people died of cancer. The prevention of cancers, therefore, offers the potential to considerably reduce the societal burden of these diseases. Cancer screening tests and examinations aim to detect cancer or precancerous conditions at an early stage and thus to increase chances for treatment, cure and survival. Since early detection strategies have both beneficial and adverse effects, they need to be monitored and evaluated continuously. This cumulative dissertation examined the opportunities and limitations of German health insurance claims data for monitoring and evaluating cancer screening tests and examinations implemented on a national scale. Based on claims data provided by the BARMER, specific research questions were addressed in four separate publications which came to the conclusions that i) the coding quality of outpatient breast, prostate and colorectal cancer diagnoses in health insurance claims data is limited, ii) the number of incident breast, prostate and colorectal cancer cases identified in health insurance claims data depends on the length of the lookback period, the length of the confirmation period for confirmatory events and the definition of confirmatory events, iii) health insurance claims data-based comorbidity measures are insufficient for controlling selection bias in observational studies of mammography screening, and iv) health insurance claims data are suitable for assessing and explaining geographic variations in mammography screening participation. Health insurance claims data offer opportunities for monitoring and evaluating cancer screening tests and examinations thanks to their ready availability, large study populations, long observation periods, high level of detail, diversity of applicable study designs and diversity of examinable outcomes. Limitations arise from incomplete information on confounders, missing information on the cause of death and tumor stages, missing internal and external validation studies, selection bias, misclassification, restrictions on internal and external validity as well as data protection regulations. To fully exploit the potential of health insurance claims data for monitoring and evaluating cancer screening tests and examinations implemented nationwide, the data should be linked to survey and cancer registry data. Moreover, further validation studies should be conducted and the methods for monitoring and evaluating national cancer screening tests and examinations should be standardized focusing particularly on the control of selection bias and quantification of effects
Scanning Kelvin Probe study of electrochemical delamination in adhesively bonded joints
Adhesive bonding is a key technology for the construction of lightweight components and its interest in the industry is increasing due to the several advantages when compared to other joining technologies. A major concern is the long-term stability of adhesive joints, especially for metallic substrates exposed to corrosive media. The aim of this work is to investigate the delamination mechanisms occurring in a real closed adhesive joint geometry. To achieve this purpose, the potential distribution at the metal/polymer interface was measured by means of Scanning Kelvin Probe (SKP) through a thin layer of glass. Quantitative measurements of the delamination kinetics were performed, accompanied by XPS inspection of the fracture surfaces. The delamination rate was found to be hundred times slower than in an open joint geometry. Furthermore, the delamination-limiting step for the open joint is the transport of cations, whereas for the closed joint is limited by the ingress of oxygen along the interphase. The cathodic delamination was the mechanism taking place in both cases, however depending on the geometry of the closed joint also the anodic undermining mechanism was found to occur
Robot Navigation in Distorted Magnetic Fields
This thesis investigates the utilization of magnetic field distortions for the localization and navigation of robotic systems. The work comprehensively illuminates the various aspects that are relevant in this context. Among other things, the characteristics of magnetic field environments are assessed and examined for their usability for robot navigation in various typical mobile robot deployment scenarios. A strong focus of this work lies in the self-induced static and dynamic magnetic field distortions of complex kinematic robots, which could hinder the use of magnetic fields because of their interference with the ambient magnetic field. In addition to the examination of typical distortions in robots of different classes, solutions for compensation and concrete tools are developed both in hardware (distributed magnetometer sensor systems) and in software. In this context, machine learning approaches for learning static and dynamic system distortions are explored and contrasted with classical methods for calibrating magnetic field sensors. In order to extend probabilistic state estimation methods towards the localization in magnetic fields, a measurement model based on Mises-Fisher distributions is developed in this thesis. Finally, the approaches of this work are evaluated in practice inside and outside the laboratory in different environments and domains (e.g. office, subsea, desert, etc.) with different types of robot systems
Structural elucidation and quantification of novel toxins in marine microalgae by NMR- and molecular modelling-based techniques
Marine biotoxins produced by dinoflagellates exhibit a remarkable structural diversity. During the course of this thesis, I present the elucidation of six novel compounds in total, two for each of the toxin groups of azaspiracids, gymnodimines, and spirolides. The LC-MS based quantification, as used in shellfish surveillance, of the novel azaspiracids was compared with NMR based quantification. Further, four cyclic imine toxins had their full relative stereochemistry elucidated. The simulated chemical shifts revealed a systematic effect between the chirality at C 4 and neighboring nuclei. Based on this systematic effect, reasonable doubts arise towards determination of R configuration at C-4 in 13,19-didesmethyl SPX C. The configuration of C-4 was assigned with simulated and measured NMR spectra, suggesting that all tested GYMs and SPXs have the S configuration at that position. This assignment supports the hypothesis of a common biosynthetic pathway for both compound groups
Fachtag Sprache: Der Förderschwerpunkt Sprache in der inklusiven Schule
Der Förderschwerpunkt Sprache in der inklusiven Schule stellt hohe Anforderungen an eine multiprofessionelle Kooperation. Diese verbindet das gemeinsame Ziel, Kinder und Jugendliche bestmöglich alltags- und bildungsorientiert zu versorgen, um ihre chancengerechte sprachliche Teilhabe zu ermöglichen und in dieser Hinsicht ihre Lebensqualität nachhaltig zu verbessern. Im Oktober 2019 hat das Multiprofessionelle Netzwerk Sprache und Kommunikation im Land Bremen den Fachtag Sprache 2019 - Der Förderschwerpunkt Sprache in der inklusiven Schule erfolgreich an der Hochschule Bremen ausgerichtet. Im Vordergrund standen Fragen zu Förderung und Therapie bei Sprach-, Sprech- und Kommunikationsstörungen bei Mehrsprachigkeit sowie bei selektivem Mutismus. Außerdem konkrete sprachheilpädagogische Impulse für die schulische Praxis und eine interaktive, multiprofessionell besetzte Plenardiskussion. Im Rahmen der Veranstaltungsevaluation wurden Daten zum beruflichen Tätigkeitsfeld der TeilnehmerInnen erhoben und die diese zur aktuellen inklusiven Versorgungssituation im Land Bremen befragt. An der Befragung nahmen 93 TeilnehmerInnen, darunter Lehrkräfte aus Bremer Schulen, SonderpädagogInnen, andere pädagogische Fachkräfte sowie LogopädInnen und SprachtherapeutInnen, und MedizinerInnen und PsychologInnen, teil. Die Vorträge und Ergebnisse dieser einschlägigen Veranstaltung wurden im vorliegenden Tagungsbericht zusammengefasst. Als ein wesentliches Ergebnis beider Fachtage lässt sich die Forderung nach einer engeren Kooperation von Bildung und Gesundheit (Logopädie) formulieren
EUX et NOUS La place des Autochtones dans l'enseignement de l'histoire nationale du Quebec Volume 3
La presente etude se presente en trois volumes. Elle analyse la place allouee a l histoire autochtone dans l enseignement scolaire et l image qu il transmet des Autochtones et de leur role dans l histoire canadienne et quebecoise. La constitution implicite ou explicite d un NOUS collectif par rapport a l AUTRE sera au centre de notre interet. Un premier volume ( urn:nbn:de:gbv:46-00106629-19 / http://nbn-resolving.de/urn:nbn:de:gbv:46-00106629-19) analyse les contenus et des discours des manuels d histoire, a commencer par les manuels approuves par le Ministre de l'Education, du Loisir et du Sport du Quebec du programme Histoire et education a la citoyennete au second cycle de l enseignement secondaire et les manuels actuels du primaire. Ensuite, pour saisir l evolution entre les annees 1970 et nos jours, nous procederons a l analyse des manuels les plus repandus des annees 1980 et 1990 du programme Histoire du Quebec et du Canada . Dans le second volume (urn:nbn:de:gbv:46-00106630-18 / http://nbn-resolving.de/urn:nbn:de:gbv:46-00106630-18), nous nous interesserons dans le detail a la perception de l histoire autochtone dans la conscience des jeunes, aussi bien francophones, anglophones et autochtones en analysant un millier de copies d eleves a travers le Quebec. Il s agira ainsi de mieux comprendre quels roles ils leur attribuent dans la trame de l histoire nationale, quelles hypotheses ils font pour combler des lacunes apparentes et comment ils construisent leur NOUS respectif, par rapport aux AUTRES. Ce troisieme volume contient l'analyse des manuels definitifs du nouveau programme Histoire du Quebec et du Canada des annees 2016-17-18. Pour conclure l ensemble, le discours majoritaire dans l enseignement de l histoire nationale y est confronte a celui de manuels d histoire autochtones concus specialement pour eux
Evolutionary Legged Robotics
Due to the technological advance, robotic systems become more and more interesting for industrial and home applications. Popular examples are given by robotic lawn mower, robot vacuum cleaner, and package drones. Beside the toy industry, legged robots are not as popular, although they have some clear advantages compared to wheeled systems. With their flexibility concerning the locomotion, they are able to adapt their walking pattern to different environments. For instance they can walk over obstacles and gaps or climb over rubble and stairs. Another possible advantage could be a redundancy for locomotion. A faulty motor in one limb could be compensated by other motors in the kinematic chain. As well, multiple failing legs can be compensated by an adapted walking pattern. Compared to this, the more complex mechatronic systems represent a major challenge to the construction and the control. This thesis is dedicated to the control of complex walking robots. Genetic algorithms are applied to generate walking patterns for different robots. The evolutionary development of walking patterns is done in a simulation software. Results of various approaches are transferred and tested on existing systems which have been developed at RIC/DFKI. Different robotic systems are used to evaluate the generality of the applied methods. Eventually, a method is developed that can be utilized, with a few system specific modifications, for a variety of legged robots. As basis for the development and investigation of several methods, software tools are designed to generalize the application of applying genetic algorithms to legged locomotion. These tools include a simulation environment, a behavior representation, a genetic algorithm and a learning and benchmark framework. The simulation environment is adapted to the behavior of real robotic systems via reference experiments. In addition, the simulation is extended by a foot contact model for loose surfaces. The evaluation of the genetic algorithm is done on several benchmark problems and compared to three existing algorithms. This thesis contributes to the state of the art in many areas. The developed methodology can easily be applied to several complex robotic systems due to its transferability. The genetic algorithm and the hierarchical behavior representation provide a new opportunity to control the generation of the offspring in an evolutionary process. In addition, the developed software tools are an important contribution for their respective research fields
Synthesis and Characterization of Copper Hexacyanoferrate and its Analogues as Cathode Material for Aqueous Zinc-Ion Batteries
There is a current global need of clean energy sources to replace the non-renewable fossil fuels due to the global warming and environmental impacts. Therefore, renewable energy sources such as solar and wind have attracted wide attention as clean energy to meet the worldwide energy demand. Since these resources are inherently intermittent, a scalable low-cost energy storage system with long lifetime is needed to integrate these sources to the grid-scale. Among different energy storage technologies, batteries are the best choice for the integration in renewable energy systems. In the last decades, among rechargeable batteries, aqueous metal-ion batteries provide lower cost, are environmentally friendly, safe, and nontoxic systems. This makes them a potential choice for grid-scale energy storage. In this Ph.D. work the focus is on the development of an aqueous zinc-ion battery based on derivatives of the Prussian blue family that can provide high specific energy and power