11210 research outputs found
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The Pulse, 1991 Spring
No full textDreyer Medical Clinic, Aurora, IL: An issue of The Pulse, a publication for Dreyer Medical Clinic patients. This was a newsletter published for patients reporting on Dreyer news, events, classes, and staffing updates.https://institutionalrepository.aah.org/alldocuments/2047/thumbnail.jp
Nursing Now, 2005 November - December
No full textAdvocate Christ Medical Center and Hope Children\u27s Hospital, Oak Lawn, IL: Internal newsletter publication written by nurses for nurses and published 6 times a year (bi-monthly). The mission of NURSING Now was to communicate, educate and motivate CMC nursing professionals towards continued excellence.https://institutionalrepository.aah.org/alldocuments/2124/thumbnail.jp
Diagnostic accuracy of artificial-intelligence-based electrocardiogram algorithm to estimate heart failure with reduced ejection fraction: A systematic review and meta-analysis
No full textIntroduction:AI-based ECG has shown good accuracy in diagnosing heart failure. However, due to the heterogeneity of studies regarding cutoff points, its precision for specifically detecting heart failure with left ventricle reduced ejection fraction (LVEF
Aims:We conducted a meta-analysis and systematic review to evaluate the accuracy of artificial intelligence electrocardiograms in estimating an ejection fraction below 40 %.
Methods:We searched PubMed, Embase, and Cochrane Library for studies evaluating the performance of AI ECGs in diagnosing heart failure with reduced ejection fraction. We computed true positives, true negatives, false positives, and false negatives events to estimate pooled sensitivity, specificity, and area under the curve, using R software version 4.3.1, under a random-effects model.
Results:We identified 9 studies, including patients with a paired artificial intelligence-enabled electrocardiogram with an echocardiography. patients had an ejection fraction below 40 % according to the echocardiogram. The AI-ECG data yielded areas under the receiver operator of, the sensitivity of), specificity of, and area under the curve of. The mean/median age ranged from 60±9 to 68.05± 11.9 years.
Conclusions:In this systematic review and meta-analysis, the use of electrocardiogram-based artificial intelligence models demonstrated high sensitivity and specificity to estimate a left ventricular ejection fraction below 40 %
Expanding the clinical horizon of transcatheter interventions: Addressing the complications of endocarditis
No full textFrequency of RAS family gene mutations in metastatic solid tumors in Venezuela: Experience at a large academic center
No full textPortal venous gas: A benign finding in pyloric stenosis?
No full textPyloric stenosis is a condition of infancy characterized by hypertrophy of the pylorus, which can progress to significant narrowing and near-obstruction of the gastric outlet. We describe a case of a patient with pyloric stenosis who was incidentally found to have portal venous gas on ultrasound. While the presence of portal venous gas can be an ominous finding, this case demonstrates that in the setting of pyloric stenosis, portal venous gas may be benign in nature. Additionally, we compile information from previous studies to further promote general recognition of this association and propose potential future standardization of care for these patients with an apparent benign finding
Transforming Health Care Through Research: Highlights From the 2025 Annual Conference of the Health Care Systems Research Network
No full textDuring this unprecedented time of uncertainty and disruption, the 2025 Annual Conference of the Health Care Systems Research Network (HCSRN) took place on April 8 to 10, 2025, in St. Louis, Missouri, at the Marriott St. Louis Grand. Nearly 265 participants from 19 HCSRN member institutions came together to network, collaborate, and connect at the conference, which featured the theme, “Optimizing Collaborations to Advance Health in a Dynamic Research Landscape.
Abstracts From the 2025 Health Care Systems Research Network (HCSRN) Annual Conference, St. Louis, Missouri
No full textThe Health Care Systems Research Network (HCSRN) comprises 19 learning health systems with integrated care delivery and embedded research units. The network’s annual conference serves as a forum for research teams from member institutions to disseminate project findings, explore scientific collaborations, and share insights about population-based research practices that can measurably improve health and health care for all. The theme of this year’s conference was “Optimizing Collaborations to Advance Health in a Dynamic Research Landscape.” Abstracts presented at HCSRN 2025 are published in this issue supplement of the Journal of Patient-Centered Research and Reviews, the journal of record for HCSRN’s annual conference proceedings
Vaginal pharmacomicrobiomics modulates risk of persistent and recurrent bacterial vaginosis
No full textBacterial vaginosis (BV) is the most commonly diagnosed vaginal infection in women of reproductive age, with most patients unaware that they have BV due to its asymptomatic nature. BV is a dysbiotic condition defined by a deviation from the healthy Lactobacillus dominance to a polymicrobial anaerobic bacterial community that increases the risk of sexually transmitted infections and adverse reproductive outcomes, including spontaneous preterm birth. The increasing number of infectious agents in BV, biofilm persistence and antibiotic resistance in the vaginal canal hinder effective treatments with antibiotics leading to consistent recurrence of BV in many women (30-70%). Like in the gut, these vaginal drug-microbiome interactions termed pharmacomicrobiomics could alter drug disposition, mechanism of action, and toxicity that reduce the efficacy of antibiotics and increase the risk of persistent and recurrent BV and its sequelae. For instance, both vaginal epithelial and bacterial cells co-exist and possess enzymes that metabolize antibiotics, and transporter proteins that expel drugs and toxins, rendering them ineffective. Despite significant progress on pharmacomicrobiomics in the gut, little is known about this phenomenon in the vaginal microenvironment, which harbors a consequential microbiota and a major source of infection and antibiotic resistance. Therefore, to improve therapeutic outcomes and reduce the rate of persistent/recurrent BV and infection-associated preterm birth, we present an overview of the evidence pertaining to the effect of vaginal microbiome-drug interactions and efficacy of antibiotics against recurrent BV. We also highlight plausible mechanistic underpinnings of these interactions and implications for treatment modalities to combat infection-associated preterm birth
