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Type 1 diabetes mellitus and thromboembolism in pregnancy
Objective:The impact of type 1 DM (T1DM) on thromboembolism in pregnancy is uncertain. We hypothesized that T1DM is associated with higher rates of thrombotic events during pregnancy and the postpartum period.
Study Design: This is a retrospective cohort study utilizing the National Inpatient Sample database from HCUP/AHRQ for 2017-2019. Pregnant and postpartum patients with a history of T1DM were compared to those without. The primary outcome was a composite diagnosis of any thrombotic disease (pulmonary embolism (PE), deep vein thrombosis (DVT), cerebral vascular thrombosis (CVT), or other thromboses). Secondary outcomes were the diagnosis of each individual type of thrombo-embolic event. Groups were compared via Student\u27s test, chi-squared, and logistic regression analyses, controlling for confounders including age, race, obesity, tobacco use, cHTN, asthma, anemia, and cesarean section.
Results: A total of 2,361,711 subjects met criteria. Patients with T1DM encompassed 0.4% of subjects (N=9,983). T1DM subjects were more likely to be younger, non-Hispanic white, obese, tobacco users, chronic hypertensive, asthmatic, and have a history of cesarean (all p\u3c 0.001). They were less likely to be in the top income quartile. Thrombo-embolic events occurred more frequently in those with T1DM (0.45% vs 0.20%, p\u3c 0.001). DVT was the most common event (0.25%). After controlling for confounders, T1DM remained independently associated with any thromboembolic event in pregnancy (aOR 2.19, 95%CI 1.49-3.23), PE (aOR 3.59, 95%CI 1.65-7.82), and DVT (aOR 2.43, 95%CI 1.43-4.14).
Conclusion: T1DM is associated with an increased risk of thrombo-embolic events in pregnancy
Dreyer Heartbeat, 1995-1996 December-January
Dreyer Medical Clinic, Aurora, IL: An issue of Dreyer Heartbeat. This was an employee newsletter published by the marketing department, reporting on news, events, and staffing updates at Dreyer Medical Clinic.https://institutionalrepository.aah.org/alldocuments/1924/thumbnail.jp
Heartbeat, 1996 April
Dreyer Medical Clinic, Aurora, IL: An issue of Dreyer Heartbeat. This was an employee newsletter published by the marketing department, reporting on news, events, and staffing updates at Dreyer Medical Clinic.https://institutionalrepository.aah.org/alldocuments/1925/thumbnail.jp
Heartbeat, 1996 October
Dreyer Medical Clinic, Aurora, IL: An issue of Dreyer Heartbeat. This was an employee newsletter published by the marketing department, reporting on news, events, and staffing updates at Dreyer Medical Clinic.https://institutionalrepository.aah.org/alldocuments/1934/thumbnail.jp
Heartbeat, 1997 August
Dreyer Medical Clinic, Aurora, IL: An issue of Dreyer Heartbeat. This was an employee newsletter published by the marketing department, reporting on news, events, and staffing updates at Dreyer Medical Clinic.https://institutionalrepository.aah.org/alldocuments/1937/thumbnail.jp
Heartbeat, 1997 February
Dreyer Medical Clinic, Aurora, IL: An issue of Dreyer Heartbeat. This was an employee newsletter published by the marketing department, reporting on news, events, and staffing updates at Dreyer Medical Clinic.https://institutionalrepository.aah.org/alldocuments/1939/thumbnail.jp
Heartbeat, 1999 September
Dreyer Medical Clinic, Aurora, IL: An issue of Dreyer Heartbeat. This was an employee newsletter published by the marketing department, reporting on news, events, and staffing updates at Dreyer Medical Clinic.https://institutionalrepository.aah.org/alldocuments/1970/thumbnail.jp
Heartbeat, 2000 December
Dreyer Medical Clinic, Aurora, IL: An issue of Dreyer Heartbeat. This was an employee newsletter published by the marketing department, reporting on news, events, and staffing updates at Dreyer Medical Clinic.https://institutionalrepository.aah.org/alldocuments/1973/thumbnail.jp
Heartbeat, 2002 April
Dreyer Medical Clinic, Aurora, IL: An issue of Dreyer Heartbeat. This was an employee newsletter published by the marketing department, reporting on news, events, and staffing updates at Dreyer Medical Clinic.https://institutionalrepository.aah.org/alldocuments/1995/thumbnail.jp
Heartbeat, 2003 March
Dreyer Medical Clinic, Aurora, IL: An issue of Dreyer Heartbeat. This was an employee newsletter published by the marketing department, reporting on news, events, and staffing updates at Dreyer Medical Clinic.https://institutionalrepository.aah.org/alldocuments/2014/thumbnail.jp