11210 research outputs found
Sort by
Maternal social deprivation and risk of preeclampsia
No full textOBJECTIVES: We examined the use of an indicator of the cumulative effect of multiple community-level risk factors on risk of preeclampsia, a morbid maternal hypertensive disorder.
STUDY DESIGN: This was a retrospective cohort study of 41,834 singleton pregnancies from four urban hospitals.
MAIN OUTCOME MEASURES: We used the social deprivation index (SDI), which is a composite of seven neighborhood demographic characteristics collected by the American Community Survey. SDI quartile 1 (Q1) is the least deprived area and Q4 is the most deprived. A modified Poisson regression model with robust error variance was used to calculate the relative risk (RR) and 95% confidence interval for the association between SDI quartiles (using Q1 as a reference) and preeclampsia. Preeclampsia subtypes were examined as secondary outcomes (term preeclampsia and preterm preeclampsia). Models were adjusted for maternal age, education, insurance, chronic health diseases, tobacco use, and gravidity.
RESULTS: Overall, 8.7% of our population had a preeclampsia diagnosis. Majority of the population was Hispanic, had lower education levels, and were on public insurance. Those living in the highest quartile of social deprivation had increased risk of preeclampsia (RR 1.25, 95% CI 1.15-1.35). However, results were null after adjustments. In contrast, living in the highest quartile of social deprivation was associated with increased risk of preterm preeclampsia, even after adjustments (RR 1.26, 95% CI 1.05-1.50).
CONCLUSION: Using electronic health records, the SDI may be an easily calculable measure to identify patients at risk for the preterm preeclampsia subtype
The acute effects of nicardipine in postoperative paediatric cardiac surgical patients under 12 months of age: A descriptive study utilising high-fidelity physiologic streaming data
No full textBackground: Utilisation of nicardipine in the neonatal and infant period has been historically avoided due to a concern for a more calcium-sensitive myocardium. The aim of this study was to characterise the association between nicardipine and systolic blood pressure in neonates and infants after cardiac surgery.
Methods: In this single-centre, retrospective study, patients under 12 months of age who underwent cardiac surgery and received nicardipine for at least one hour were included (September 2022 to January 2024). Patients were monitored with Etiometry. Variables of interest included haemodynamic parameters, ionised calcium, serum lactate, vasoactive infusion score, and nicardipine dose. A time series regression was conducted with each patient having 5 distinct time points.
Results: One hundred and eighty-five time points were collected across 37 patients with a mean age of 3 months. Of these patients, 22% were neonates and 32% were functionally univentricular. With nicardipine utilisation, a decrease in systolic blood pressure of 14 mmHg after an 8-hour time period was noted (p = 0.017). Heart rate, diastolic blood pressure, cerebral and renal oxygen extraction, ionised calcium, serum lactate, and vasoactive inotrope score did not significantly change over the study period.
Conclusion: Nicardipine utilisation in neonates and infants after cardiac surgery was associated with decreased systolic blood pressure. Indirect markers demonstrate no change in cardiac function. Additional studies are needed to better elucidate nicardipine\u27s role in this patient population
How soon is too soon? The association between observation time of supplemental oxygen and readmission rates for infants hospitalized with bronchiolitis
No full textImpact of a nurse-led in-hospital mobility intervention on older adult patient functional outcomes and perceptions
No full textHospital-associated disabilities in older adults are common. Few studies have used a performance measure to evaluate the impact of ambulation on patient functional status during and after discharge or investigated older adult perceptions of ambulation during a hospitalization. The purpose of this study was to evaluate the implementation of MOVIN (Mobilizing Older adults Via a systems-based INtervention) on older adult functional performance outcomes and to understand patients perceptions of mobility during their hospital stay. A non-randomized observational study using a quasi-experimental design was conducted. Multiple methods using quantitative and qualitative approaches were used. Functional measures included gait speed and self-report on the Katz Activities of Daily Living scale and the University of Alabama at Birmingham (UAB) Life Space Mobility Index. In-person interviews were used to collect qualitative data. The study was conducted on a 23-bed adult medical unit at an academic medical center. Older adults (N = 40) were recruited for data collection during their hospital stay and post-discharge. General linear mixed random-effects modeling was used to analyze functional outcomes. Inductive content analysis was used to analyze qualitative data. The intervention group had a significant increase in gait speed at discharge compared to admission (p = 0.022) and at 3 months (p = 0.006) compared to discharge and a significant increase in UAB score between admission to 3 months post-discharge (p = 0.049). Qualitative results identified four categories Maintaining Health, Being Connected, Filling Time and Ready to Go Home, which describe the patient perception. This study provides evidence that an in-hospital mobility intervention can have significant impacts on older adults functional performance and psycho-social outcomes
Lifestyle habits and structural heart abnormalities among former athletes and their families: HUDDLE subanalysis
No full textINTRODUCTION: Cardiovascular disease is the leading cause of death globally. Understanding the association between lifestyle habits, risk factors, and structural heart abnormalities is crucial for developing preventive strategies, especially among understudied populations. METHODS: The HUDDLE trial was a cross-sectional study of National Football League alumni and their family members aged ≥50 years who self-reported health histories and underwent noninvasive cardiovascular disease screening, including transthoracic echocardiography. Cardiovascular disease risk factors were evaluated using a modified American Heart Association Life\u27s Simple 7 (physical activity, tobacco use, obesity, hypertension, diabetes, alcohol intake, and hyperlipidemia) and assessed as ideal, intermediate, or poor. RESULTS: Of 498 participants, 92.4% had at least 1 poor health metric, with 15.9% having ≥3. Former National Football League players aged \u3c 65 years had a higher prevalence of ≥3 poor metrics compared with other participants. Non-White former National Football League players exhibited nearly double the prevalence of having 3 or more poor health metrics as their White counterparts (23.9% vs 12.0%). Compared with those with no poor metrics, participants with 3-7 poor metrics had the highest odds of having structural heart abnormality (OR=2.40; 95% CI=1.08, 5.32), followed by those with 2 (OR=2.39; 95% CI=1.16, 4.92) and 1 (OR=1.79; 95% CI=0.87, 3.66) poor metric. CONCLUSIONS: This subanalysis of the HUDDLE study identified a high prevalence of poor health metrics among former National Football League players and their families. Younger, non-White participants were more likely to have worse lifestyle habits than their counterparts. Increasing number of poor health metrics was associated with structural heart abnormalities
Inside Aurora Sinai Medical Center, 2002 June
No full textAurora Sinai Medical Center, Milwaukee, WI: Internal employee newsletter with workplace anniversaries, news, and events.https://institutionalrepository.aah.org/alldocuments/2242/thumbnail.jp
Inside Aurora Sinai Medical Center, 2002 February
No full textAurora Sinai Medical Center, Milwaukee, WI: Internal employee newsletter with workplace anniversaries, news, and events.https://institutionalrepository.aah.org/alldocuments/2238/thumbnail.jp
Inside Aurora Sinai Medical Center, 2003 July
No full textAurora Sinai Medical Center, Milwaukee, WI: Internal employee newsletter with workplace anniversaries, news, and events.https://institutionalrepository.aah.org/alldocuments/2253/thumbnail.jp