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Young female with calcaneal chondroblastoma & secondary aneurysmal bone cyst: Case report
No full textIntroduction: Calcaneal chondroblastoma with secondary aneurysmal bone cyst is an exceptionally rare occurrence with few cases published in the literature. Differentiating primary aneurysmal bone cyst from secondary aneurysmal bone cyst in the setting of chondroblastoma is important as it has implications for orthopedic management and follow up. This case illustrates the transition from an initial impression of an aneurysmal bone cyst to the definitive diagnosis of an underlying chondroblastoma, leading to appropriate treatment and a positive outcome.
Case report: A 20-year-old Hispanic female presented with a lytic lesion in the left calcaneus, initially suspected to be an aneurysmal bone cyst. Histopathological examination confirmed chondroblastoma with secondary ABC. The patient underwent extended curettage with bone grafting, supplemented by adjuvant therapy using argon gas and hydrogen peroxide. Postoperatively the patient had a good outcome with no evidence for recurrence at time of last exam.
Conclusion: Chondroblastoma with secondary aneurysmal bone cyst in the calcaneus is an exceptionally rare event that requires a comprehensive diagnostic and therapeutic approach. Early recognition and appropriate surgical management are crucial to achieving favorable outcomes and minimizing the risk of recurrence. Continued research and case documentation are necessary to further understand the optimal management strategies for this unique clinical presentation
Human Ecology, 1973 Winter, V4 N2
No full textLutheran General Hospital, Park Ridge, IL: Magazine published quarterly by the Lutheran General and Deaconess Hospitals. This publication keeps employees and friends of the hospital informed on current news and hospital updates.https://institutionalrepository.aah.org/alldocuments/2224/thumbnail.jp
Comparison of survey questions to define long COVID: Implications for prevalence and disparities
No full textObjective: To understand whether variation in survey-based Long COVID estimates is partially due to how and when survey questions are asked.
Methods: We compared Long COVID prevalence using distinct questions within a population-based, longitudinal survey of adults with confirmed SARS-CoV-2 before June 2022 in Michigan.
Results: In our sample (n = 3826), 17.0 % reported symptoms for 90+ days at baseline, a median of 4.4 months after COVID-19 onset. A median of 18.4 months after COVID-19 onset, 24.5 % reported ever experiencing Long COVID, 16.9 % reported current Long COVID, and 10.8 % reported diagnosed Long COVID. Among adults without 90-day symptoms at baseline, 17.3 % reported ever Long COVID at follow-up. Relatedly, among adults with 90-day symptoms at baseline, 31.1 % reported they never had Long COVID at follow-up. After adjustment for reinfection, respondents who were Hispanic (vs. White) or lower income (
Conclusion: Surveys should employ several questions to define Long COVID and interpret findings within the context of factors likely contributing to discrepancies, including reinfection, stigma, awareness, and care-seeking behaviors
TCT-250 Persistent age-related disparities in mortality among STEMI patients with cardiogenic shock: A 15-year national analysis
No full textKey articles and guidelines in the management of chronic coronary disease
No full textCardiovascular disease remains the leading cause of death; however, advances in the acute management of cardiovascular events have resulted in a greater number of patients who require chronic management to prevent future events. The care of these patients in the post-acute care phase was historically referred to as stable ischemic heart disease (SIHD) but is now collectively referred to as chronic coronary disease (CCD). In 2023, the chronic coronary disease guidelines were released and consolidated prior guidelines on secondary prevention and managing stable ischemic heart disease. The role of pharmacotherapy for CCD has expanded significantly in recent decades due to emerging evidence from clinical trials and the development of novel drug therapies. This manuscript summarizes key articles and guidelines that will serve as an important resource for clinicians responsible for caring for patients with chronic coronary disease
Relationship between inflammation-nutrition composite indices and ovarian endometrioma: A retrospective observational study
No full textObjective: Endometriosis is a chronic inflammatory disease with impacts on reproduction, health and quality of life, yet its diagnosis is often delayed. Ovarian endometrioma (OMA) is the most common subtype of endometriosis. The establishment of simple predictive indicators could screen women at high risk of OMA, thereby potentially facilitating the early diagnosis and management of endometriosis. This study aimed to comprehensively evaluate the predictive performance of inflammation and inflammation-nutrition composite indices for ovarian endometrioma (OMA) among women of reproductive age in China.
Methods: A total of 333 women with diagnosed OMA and 506 controls were included in this study. Inflammation indices including neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), systemic immune inflammation index (SII) and inflammation-nutrition composite indices including neutrophil percentage‑to‑albumin ratio (NPAR), NLR/AGR, PLR/AGR, SII/AGR and neutrophil percentage/AGR(NP/AGR) were calculated. Multivariate logistic regressions were used to assess the associations of indices with OMA. Receiver operating characteristic (ROC) curves and areas under the curve (AUCs) were used to evaluate the predictive value of indices for OMA.
Results: Compared with women without OMA, inflammation indices (NLR, PLR, SII) and inflammation-nutrition composite indices (NPAR, NLR/AGR, PLR/AGR, SII/AGR, NP/AGR) in patients with OMA showed a significant increase. Subjects in the higher tertile of these indices had a significantly increased risk of OMA compared with those in the lower tertile (P \u3c 0.01). NP/AGR had the greatest total AUC (AUC = 0.799) in the ROC curve analysis.
Conclusion: NPAR, NLR/AGR, PLR/AGR, SII/AGR and NP/AGR could provide additional clinical diagnostic value for OMA as non-invasive and cost-effective tests, and are better than inflammation indices (NLR, PLR, SII) alone. Among them, NP/AGR might be the best predictor
National Mortality and Resource Utilization in Ischemic vs. Non-Ischemic Cardiogenic Shock Treated With Destination Left Ventricular Assist Device
No full textQuantifying the effective cricoid force to occlude the esophageal entrance in anesthetized and muscle-relaxed children: A videolaryngoscopy-based assessment
No full textBackground: When cricoid pressure was introduced in pediatric anesthesia, the cricoid force was not defined, leading pediatric anesthesiologists to question its necessity, effectiveness, and safety. We hypothesized that airway complications encountered in clinical practice may have resulted from the exertion of excessive cricoid force.
Methods: Using a novel instrument, we measured cricoid force during Glidescope® videolaryngoscopy in three groups of 40 anesthetized children: Group 1 (3 to 5 years), Group 2 (6 to 8 years), and Group 3 (9 to 14 years). A biased-coin up-and-down design was employed to estimate the median force required to prevent the insertion of a suction catheter into the esophagus.
Results: There were no instances of difficult endotracheal intubation. The median cricoid force required to prevent suction catheter insertion into the esophagus in 90% of patients was 4.85 Newton (N) (95% CI 4.12 to 7.34) in Group 1, 8.74 N (95% CI 8.30 to 9.73) in Group 2, and 13.0 N (95% CI 11.2 to 16.9) in Group 3.
Conclusions: Age-appropriate cricoid force applied under videolaryngoscopic guidance effectively occludes the esophageal entrance without compromising endotracheal intubation. These forces are substantially lower than the thresholds known to cause airway distortion or obstruction in children and are lower than the force recommended for adults. These findings may have implications for the use of cricoid pressure as a component of the rapid sequence intubation (RSI) technique in children at risk of pulmonary aspiration
