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Evaluation of renal elasticity by shear wave elastography in children with Familial Mediterranean Fever
Get PDFBackground Familial Mediterranean Fever (FMF) is a genetic disorder that can cause kidney damage. Shear wave elastography (SWE), a non-invasive method, was used to evaluate the decrease in renal tissue elasticity as a predictive parameter for amyloidosis. This study aimed to examine the changes in renal elasticity in patients with FMF using the renal SWE measurement method. Methods The present study included 50 pediatric patients diagnosed with FMF. The median SWE values of both kidneys were compared between the groups. Acute phase reactants were also evaluated. Results The SWE measurements (for the left kidney p = 0.007, for the right kidney p = 0.06) and proteinuria levels (p < 0.001) of the patient group were found to be higher than those of the control group. No correlation was observed between the disease activity score and the SWE measurements. Erythrocyte sedimentation rate (p < 0.001), C-reactive protein (p < 0.001) and urine protein/creatinine ratio (p < 0.001) were significantly higher in the remission period compared to the control group, whereas estimated glomerular filtration rate was found to be low in the patient group (p < 0.001), which was considered as an indicator that subclinical inflammation continued in the course of the disease. Conclusions The acute phase reactants were elevated in patients with FMF even in the remission period which indicates that the disease is constantly active and have the potential to cause damage in all organs and tissues. It is thought that this subclinical inflammation may also contribute to increased tissue stiffness, which may serve as a predictor for the development of amyloidosis
Evaluation of the Archaeobotanical Remains of the Early Bronze Age Level III of Seyitömer Höyük and the ethnobotanical studies of today's surrounding villages together
Get PDFBu çalışma, Kütahya İli sınırları içerisinde yer alan Seyitömer Höyük yerleşmesinin Erken Tunç Çağı III evresine ait arkeobotanik bulgular ile höyük çevresindeki yedi köy ve bir kasabada gerçekleştirilen etnobotanik verileri karşılaştırmalı olarak ele almaktadır. Araştırmanın temel amacı, tarih öncesi yerleşimlerdeki bitki kullanım uygulamalarının günümüz geleneksel bilgi sistemleriyle olası sürekliliğini ve dönüşümünü incelemektir. Arkeobotanik analizler kapsamında 214 örnek değerlendirilmiş, bunlardan 28 familyaya ait 84 takson ve toplam 530.087 adet bitki kalıntısı tespit edilmiştir. Etnobotanik saha çalışmaları çerçevesinde ise 117 katılımcı ile görüşme yapılmış; 35 familyaya ait 147 taksonun, 19 alttür, 5 varyete ve 7 endemik türün çeşitli kullanım biçimleri kaydedilmiştir. Karşılaştırmalı analiz sonucunda, arkeobotanik ve etnobotanik veriler arasında 33 taksonun kesişimi belirlenmiş; bu kesişimler üzerinden kültürel süreklilik ve değişim süreçleri yorumlanmıştır. Çalışma, arkeobotanik ve etnobotanik verilerin birlikte ele alınmasının, tarihsel ekolojik bilgi birikiminin çözümlenmesinde işlevsel bir yöntem sunduğunu ortaya koymaktadır.This study presents a comparative evaluation of the archaeobotanical data from the Early Bronze Age III phase of the Seyitömer Höyük settlement, located within the borders of Kütahya Province, and the ethnobotanical findings obtained from seven surrounding villages and one town. The primary aim of the research is to investigate the potential continuity and transformation of prehistoric plant use practices within the context of contemporary traditional knowledge systems. Within the scope of archaeobotanical analyses, 214 samples were examined, revealing 84 taxa belonging to 28 families and a total of 530,087 plant remains. In the ethnobotanical fieldwork, interviews were conducted with 117 participants, documenting various uses of 147 taxa from 35 families, including 17 subspecies, 5 varieties, and 7 endemic species. As a result of the comparative analysis, 33 overlapping taxa were identified between the archaeobotanical and ethnobotanical datasets, providing a basis for interpreting processes of cultural continuity and transformation. The study demonstrates that the joint evaluation of archaeobotanical and ethnobotanical data offers an effective methodological approach to understanding historical ecological knowledge systems
Durmuş Hocaoğlu ve Fizikten Teori Ödünç Alarak Sosyal Bilimlerde Çalışmanın İmkanını Tartışmak
Get PDFSosyal bilimlerde doğa bilimlerinin yöntemlerini kullanmaya dair tartışmalar çok uzun bir geçmişe sahiptir. Bu bakımdan Siyaset Bilimi, Uluslararası İlişkiler ve Tarih disiplinlerinde metot ve teori üzerine pek çok tartışma yapılmaktadır. Bu çalışma Herman Paul’un “Tarih Teorisi” kitabında teklif ettiği “insanların geçmişle nasıl ilişki kurduklarına dair” kavramsal analiz bağlamını başlangıç noktası kabul ederek Tarih ve Uluslararası İlişkiler disiplinlerine dair metodolojik ve teorik bilimsel bir deneme girişimidir. Bu meyanda Durmuş Hocaoğlu’nun “Laisizm’den Milli Sekülerizm’e” adlı eserinde kullandığı, elverişli bir teori olarak savladığı “domenler” ve “potansiyel” teorileri incelendi. Tarih alanında ve geniş çerçevede sosyal bilimlerde teorik bir kullanım imkânı olup olmadığı soruşturuldu. İnceleme sahası olarak Osmanlı-Türk bilim tarihi ekseninde Türk modernleşmesi seçildi. Bu bakımdan ideolojik Tarih, Siyaset Bilimi ve Uluslararası İlişkiler yazıcılığının etkilerinin azaltılması amacıyla tartışma açılması hedeflendi
Evaluating the impact of mega-projects-induced land-cover changes on habitat quality: a case study of Istanbul
Get PDFThe rapid urban expansion in mega-cities like Istanbul leads to increased habitat degradation, harming biodiversity. Since 2010, the central government of T & uuml;rkiye has proposed and implemented controversial mega-projects in Istanbul as part of neoliberal urbanisation. This study analyzes the impacts of these projects on habitat quality and land-cover changes, especially forest landscape. Results show increased urbanisation, especially in districts hosting projects like Istanbul Airport (IA), Northern Marmara Motorway (NMM), and Kanal Istanbul (KI), significantly reducing habitat quality. The study highlights the need for ecological evaluation in the spatial planning process to mitigate the environmental effects of these developments.Scientific and Technological Research Council of Tuerkiye (TUBITAK)Duzce University (DU) Scientific Research Projects Coordination Office [2023.02.01.1427]This study was supported by the Scientific and Technological Research Council of Tuerkiye (TUBITAK) under the 2214-A International Research Fellowship Programme for PhD Students Programme and the Duzce University (DU) Scientific Research Projects Coordination Office (Project no: 2023.02.01.1427)
Hüzün Turizmi Ritüeli Ölçeğinin Türkçe’ye Uyarlanması Üzerine Bir Çalışma
Get PDFBu çalışmanın amacı Sun ve Lv (2024) tarafından geliştirilen Hüzün Turizmi Ritüeli Ölçeği’nin Türkçe’ye uyarlama çalışmasını yapmaktır. İlgili ölçeğin hüzün turizmi üzerine nicel araştırma yapmayı planlayan Türk araştırmacılar için tercih edilen bir ölçek olacağı düşünülmüştür. Çalışma için gerekli veriler Gelibolu Yarımadası Tarihi Milli Parkı’nı ziyaret eden 318 ziyaretçiden toplanmıştır. Veri analizi için SPSS ve AMOS programları yardımıyla açımlayıcı ve doğrulayıcı faktör analizi, güvenirlik ve geçerlik analizleri yapılmıştır. Analizler sonucunda ölçeğin iki boyutlu yapısının doğrulandığı ve Türk kültürüne uyumlu bir ölçek olduğu görülmüştür
Investigation of plasma vitamin D, vitamin B12, and folate levels in newborns with pathological jaundice without risk factors
Get PDFBackground Physiological jaundice of the newborn is usually benign condition. Hyperbilirubinemia occurs as a result of postnatal breakdown of hemoglobin F and functional failure of the neonatal liver. Neonatal physiologic jaundice is seen in approximately two-thirds of term infants. Fifteen percent of neonatal jaundice reaches the pathological level. The etiology of nearly half of the cases is unknown. Considering the prevalence of pathological jaundice and its neurological side effects, it is very important to elucidate the etiology. This study was designed to investigate the potential role of vitamin B12, folate, and 25-OH vitamin D in the etiology of neonatal jaundice, considering their effects on erythrocyte maturation and cell lysis through various mechanisms. Methods A patient group was formed from 40 newborns and their mothers who developed pathological jaundice despite the absence of known risk factors. The control group consisted of 36 infants and their mothers who did not develop pathological jaundice. Demographic characteristics (age, gender, etc.), laboratory findings, plasma 25(OH) vitamin D, vitamin B12, and folate level results of both groups were compared. Results Newborn plasma vitamin B12 and especially plasma folate levels were significantly lower in the patient group (p 0.048, < 0.001, respectively). There was no significant difference in 25(OH) vitamin D levels in both groups. A positive correlation was found between the vitamin levels of mothers and babies. Conclusion Our study suggests that lower neonatal folate and vitamin B12 levels, along with higher maternal 25(OH) vitamin D levels, may be associated with pathological jaundice
Assessment of the influence of abrasive water jet drilling parameters on glass fiber-reinforced polymer composites
Get PDFIn this study, the effect of abrasive waterjet (AWJ) drilling of glass fiber-reinforced polymer (GFRP) composites (0 degrees/90 degrees fiber orientations) on the kerf taper (T) and roundness error (Re) of the holes was investigated. The experiments were carried out using an abrasive waterjet designed with a Taguchi L16 orthogonal array. The following waterjet processing parameters were selected: water pressure, stand-off distance, and feed rate. Statistical analyses were conducted using analysis of variance (ANOVA), signal-to-noise (S/N) ratios, and Taguchi-based gray relational analysis (GRA) to investigate the effects of processing parameters on kerf taper and roundness error. An Artificial Neural Network (ANN) model was created for the estimation of the experimental data, and the generated model was executed with minimum error and maximum accuracy. The analysis revealed that water pressure was the most influential parameter, contributing 87.75% to Re and 85.15% to T, followed by stand-off distance (11.00% for Re and 13.02% for T). Based on the parameters selected through GRA, the optimum conditions (5300 bar water pressure, 1 mm stand-off distance, 3000 mm/min traverse feed rate, 10 mm hole diameter) produced a minimum Re of 0.709 mm and a T of 0.420 degrees
The study of the development and implementation of the digital leadership skills scale of school principals according to teacher perceptions
Get PDFBu araştırma, öğretmen algılarına göre okul müdürlerinin dijital liderlik becerilerini ölçen geçerli ve güvenilir bir ölçek geliştirmeyi amaçlamaktadır. Çalışmada nicel araştı rma yaklaşımından betimsel tarama modeli kullanılmıştır. Dijital liderlik, eğitim yöneticilerinin dijital teknolojileri etkili biçimde kullanarak öğrenme ortamlarını dönüştürmeleri, öğretim süreçlerini yeniden yapılandırmaları ve paydaşlarla dijital iletiş im kurmaları süreci olarak tanımlanmıştır. Ölçek geliştirme süreci DeVellis'in ( sekiz aşamalı modeli temel alınarak yürütülmüş, başlangıçta 100 maddelik madde havuzu oluşturulmuştur. Araştırma üç aşamada gerçekleştirilmiştir. Açımlayıcı Faktör Analiz i için 298, Doğrulayıcı Faktör Analizi için 471, uygulama aşaması için 313 öğretmenden veri toplanmıştır. Katılımcılar Türkiye'nin farklı illerindeki anaokulu, ilkokul, ortaokul ve liselerinde görev yapan öğretmenlerden oluşmaktadır. AFA sonuçları ölçeğin üç faktörlü yapıya sahip olduğunu göstermiştir. Bu faktörler "Dijital Vizyon Oluşturma ve Takip Etme", "Kurum Yönetiminde Dijital Araçların Kullanımı" ve "Dijitalleşme Sürecinde Olası Tehlikelere Karşı Önlemler Alma" olarak adlandırılmıştır. KMO değeri 0.9 26, Bartlett küresellik testi anlamlı bulunmuş, üç faktör toplam varyansın %67'sini açıklamıştır. DFA bulgularında model uyum indeksleri mükemmel seviyede çıkmıştır. CFI 0.997, TLI 0.996, RMSEA 0.075 değerleri modelin veri ile çok iyi uyum sağladığın ı ortaya koymuştur. Faktör yükleri 0.694 0.920 arasında değişmiş, madde eleme sürecinde 79 madde çıkarılarak 21 maddelik nihai ölçek elde edilmiştir. Güvenirlik analizlerinde Cronbach's Alpha değerleri oldukça yüksek bulunmuştur. DFA sonrası genel ölçekte 0.967, uygulama grubunda 0.959 değerleri elde edilmiştir. Demografik değişkenler açısından erkek öğretmenlerin kadın öğretmenlere göre okul müdürlerinin dijital liderlik becerilerini anlamlı düzeyde daha yüksek algıladığı tespit edilmiştir. Mesleki kıdem d eğişkeninde uç gruplar arasında anlamlı farklılık gözlenmiştir. Bu çalışma Türkiye'deki okul müdürlerinin dijital liderlik becerilerini değerlendirmek için geçerli ve güvenilir bir ölçme aracı geliştirmiş olup, eğitim yönetimi alanında dijital liderlik kon usundaki alan yazın eksikliğini gidermeye önemli katkı sağlamaktadır.This research aims to develop a valid and reliable scale that measures the digital leadership skills of school principals according to teacher perceptions. The research utilized a descriptive survey approach from quantitive research approach. Digital leadership has been defined as the process by which education manag ers transform learning environments by using digital technologies effectively, reconstruct teaching processes and establish digital communication with stakeholders. The scale development process was carried out on the eight stage model, initially a 100 ite m pool was created. The research was carried out in three stages. Data were collected from 298 teachers for Exploratory Factor Analysis, 471 teachers for Confirmatory Factor Analysis, and 313 teachers for the implementation phase. The participants consist of teachers working in kindergartens, elementary, middle and high schools in different provinces of Turkey. The results of the EFA showed that the scale has a three factor structure. These factors were named as "Creating and Following a Digital Vision", "U sing Digital Tools in Corporate Management" and "Taking Measures Against Possible Dangers in the Digitalization Process". The KMO value was found to be 0.926, the Bartlett sphericity test was significant, and three factors explained 67% of the total varian ce. In the CFA findings, the model fit indices were found to be at an excellent level. The values of CFI 0.997, TLI 0.996, RMSEA 0.075 revealed that the model fits very well with the data. The factor loads were changed between 0.694 0.920, Decoupling 79 items during the item elimination process and obtaining a final scale of 21 items. Cronbach's Alpha values were found to be quite high in reliability analyses. After CFA, values of 0.967 were obtained in the general scale and 0.959 in the application g roup. In terms of demographic variables, it has been found that male teachers perceive the digital leadership skills of school principals to be significantly higher than female teachers. A significant difference was observed between the end groups in the o ccupational seniority variable. This study has developed a valid and reliable measurement tool for evaluating the digital leadership skills of school principals in Turkey and makes an important contribution to eliminating the lack of digital leadership lit erature in the field of educational management
The Relationship Between Emotional Availability of Parents and Difficulties in Emotion Regulation in Emerging Adults: The Mediating Role of Meta-emotion and Mood
Get PDFEffectively regulating emotions is a lifelong developmental task for every individual. In the course of an individual's development, effective emotion regulation is deeply intertwined with relationships and emotions. This study aims to explore how parental emotional availability, meta-emotion, and mood influence emotion regulation difficulties among emerging adults. In addition, this study also intends to examine the mediating role of meta-emotion and mood in the relationship between the emotional availability of parents and difficulties in emotion regulation. The participants comprised 882 emerging adults (58.2% female, 41.8% male) between the ages of 18 and 25. Hierarchical regression and bootstrapping analyses were employed to validate the research hypotheses, utilizing various psychological measurement instruments. Results indicated that positive meta-emotion, pleasant mood, and parental emotional availability negatively predicted emotion regulation difficulties, whereas negative meta-emotion and unpleasant mood positively predicted them. Additionally, it was revealed that positive meta-emotion, negative meta-emotion, pleasant mood, and unpleasant mood had a mediating role in the relationship between the emotional availability of both mothers and fathers and difficulties in emotional regulation. These findings were discussed in light of relevant literature, with implications for future research and practical applications
Electric Energy Consumption Forecast And Analysis For Duzce Province
Get PDFThe purpose of this study is to develop estimation models for the electrical energy consumption values of Düzce Province, Turkey. It has been demonstrated that estimation models were constructed and analyzed for the electrical energy consumption of Düzce between November 2019 and October 2021. To create the dataset, data were obtained monthly from Enerji Piyasaları İşletme A.Ş. (EPİAŞ). Since the data cover two periods (12 months and 24 months) and include seasonality, the Least Squares Method, Fourier Analysis, and Winters' Method were chosen as the estimation models. The evaluation of the models using the Mean Absolute Percentage Error (MAPE) method indicates that Fourier Analysis performs worse than Winters' Method. Winters' Method, which is a multiplicative model, achieved better performance in constructing the electrical energy consumption estimation model in this study. When comparing the two estimation models, no significant difference was observed; however, the analysis results reveal that Winters' Method is more favorable for forecasting electricity consumption values in Düzce for the period between November 2019 and October 2021. These findings demonstrate that Winters' Method outperforms both the Least Squares Method and Fourier Analysis, making it a more reliable option for future studies focused on constructing electricity consumption estimation models. This result emphasizes the importance of using Winters' Method as a reference for future research on electricity demand forecasting