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Jaw Solitary Plasmacytoma of Bone and Oral Extramedullary Plasmacytoma: Literature Review
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No Echo, no problem? Predictors of right heart strain among patients with pulmonary embolism
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Pointing the trident in the right direction: recognizing spinal neurosarcoidosis through a specific MRI pattern
No full textWe herein report the case of a 51-year-old male presenting with progressive neurological symptoms, including numbness, tingling below the umbilicus, urinary difficulty, constipation, and weakness. Following a recent coronavirus disease 2019 (COVID-19) vaccination, magnetic resonance imaging (MRI) revealed longitudinally extensive transverse myelitis (LETM) with a trident-shaped pattern on axial sequences, a hallmark of spinal neurosarcoidosis. Positron emission tomography-computed tomography demonstrated multiple hypermetabolic hilar and mediastinal lymphadenopathies, further supporting this diagnosis, particularly given the possibility of false-positive aquaporin-4-immunoglobulin G (AQP4-IgG) enzyme-linked immunosorbent assay (ELISA) results. Early recognition of the trident sign enabled the prompt initiation of corticosteroids and immunosuppressive therapy, highlighting the diagnostic utility of this specific MRI pattern in an appropriate clinical scenario, with primary spinal cord lymphoma as a differential diagnosis
Routine machine quality assurance tests for a self-shielded gyroscopic radiosurgery system
No full textPurpose: This report describes routine machine quality assurance (QA) (daily, monthly, and annual QA) tests for the Zap-X® Gyroscopic Radiosurgery® platform.
Methods: Following the recommendations of the American Association of Physicists in Medicine Task Group (AAPM TG)-142 and Medical Physics Practice guideline (MPPG) 8.b, routine machine QA tests for the Zap-X system were implemented. The implementation included (1) daily, monthly, and annual QA tests encompassing dosimetry, mechanical, safety and imaging tests, (2) QA methods of each test specific to the Zap-X, (3) a tolerance value for each test, and (4) necessary QA equipment.
Results: Baseline values and key results of daily, monthly, and annual QA tests are presented in this report. This report also discusses QA tests not adopted from TG 142 or MPPG 8.b (e.g., distance indicator) due to unique features of the Zap-X system as well as additional QA tests added from the vendor\u27s recommendations (e.g., self-check) and from TG-135 recommendations (e.g., monthly end-to-end testing) because of similarities between Zap-X and CyberKnife systems.
Conclusions: The comprehensive information on routine machine QA tests presented in this report will assist Zap-X teams in other Neurosurgery centers or Radiation Oncology clinics in establishing and maintaining their QA programs until AAPM endorsed guidelines become available
Weight loss, nutritional aspects and quality of life in head and neck cancer survivors
No full textObjectives: Comprehensive care is fundamental to cancer survivors enduring long-term side-effects of cancer treatment including nutrition impact symptoms and critical weight loss (CWL). The aim of our study was to address weight loss (WL), nutritional aspects, and quality of life (QoL) in head and neck cancer (HNC) survivors.
Study design: This was a cross-sectional study of HNC patients treated at the Sapienza University-Hospital, 2018-2022. We administered a modified version of the EORTC-QLQ-H&N35, the National Health and Nutrition Examination Survey for taste disorders, and the Fox Questionnaire for dry mouth. WL was recorded at T0 (before cancer treatment), T1 (right after treatment), and (at follow-up) T2.
Results: All patients (n = 63; 61.9% males) had a median WL of 16.7% (range: 1.4%-44.2%) at T1 and a median of 9.8% (range: 1.8%-45.6%) at T2. Patients with dysgeusia, poor dentition, and those who underwent major orofacial surgery had the highest WL (P \u3c .05). Patients who received multiple treatment regimens had a higher WL compared to those receiving fewer regimens (P \u3c .05). Patients with nutritional problems (71.4%) had a lower QoL throughout (P \u3c .05).
Conclusions: CWL is an important side effect of HNC treatment and may particularly affect survivors with xerostomia/dysgeusia, poor dentition, and those receiving multiple treatment regimens
Brentuximab vedotin, nivolumab, doxorubicin, and dacarbazine for advanced-stage classical Hodgkin lymphoma
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