1524 research outputs found
Sort by
THE RELATIONSHIP BETWEEN PSYCHOTHERAPIST SELF-DISCLOSURE AND OCCUPATIONAL AND EMOTIONAL VARIABLES
No full textThe effect of therapist self-disclosure practices on patients and the therapeutic relationship has long been debated. The historical trend of viewpoint toward self-disclosure began from predicting a negative, therapy-interfering stance to a growing openness towards the consideration that therapists sharing about themselves in session can have a positive effect on the patient. Evidence exists for both potential patient benefit and harm from therapists engaging in self-disclosure. Still, there is an increasing body of evidence that demonstrates that therapist self-disclosure benefits the therapeutic process, increases patient disclosure, and provides a more positive view of the therapeutic relationship. However, at present, there is limited research on the reasons why and how therapists choose to disclose, whether self-disclosure is a protective factor in the workplace, and what the effects of self-disclosure are on therapists. This study aimed to expand knowledge on identity- and lived-experience-related therapist self-disclosure from the perspective of the therapists by identifying the personal and emotional effects of self-disclosure and investigating the relationship between how therapists view therapist self-disclosure, the proportion of their patients they disclose to, their sense of occupational self-efficacy, and their sense of their work as a calling. This study found that a higher proportion of self-disclosure to patients was associated with higher levels of occupational self-efficacy and that BIPOC therapists had lower levels of occupational self-efficacy. Higher proportions of self-disclosure were associated with lower levels of experiencing work as a calling and more positive views of self-disclosure were associated with higher levels of experiencing work as a calling. Additionally, therapists reported a wide range of personal and emotional effects from self-disclosing, including both positive and negative emotions, a greater sense of purpose and connection, and experiencing tension with what they were taught in their clinical training regarding self-disclosure. These findings suggest that self-disclosure is related to the constructs of occupational self-efficacy and work calling and that the personal and emotional effects of self-disclosure are wide-ranging, as well as set a foundation for future research on therapist experiences of self-disclosure and the creation of clinical guidelines for therapists engaging in self-disclosure
SYNTHESIS AND SAR OF PARP INHIBITORY QUINOXALIN-2(1H)-ONE DERIVATIVES CARRYING POTENCY- AND SELECTIVITY-DRIVING ADENINE-BINDING MOTIFS
No full textPoly (ADP-ribose) polymerase (PARP) is a superfamily of proteins comprising 17 members, with PARP1 and PARP2 most notable for their implications in different types of cancer. PARP inhibitors represent an intriguing class of anticancer agents that have garnered increasing interest over the past decade due to their demonstrated clinical efficacy. AZD-9574 is one of these promising PARP1 selective inhibitors with good blood-brain barrier permeability that is currently in clinical trials for the treatment of solid malignancies and previous research attributed its selectivity and efficacy to the presence of a piperazine ring linker in its structure. However, a structure-activity relationship conducted with a set of truncated piperazine ring surrogates showed that this was not the case, which meant that there were other factors contributing to the activity of this compound. Encouraged by the inhibitory activity shown by pyridyl-2-carboxamide adenine-binding (AB) motif derivative 3 (PARP1/2 % inhibition = 90/17 at 100 nM) and the past work on benzimidazoles as AB motifs from our lab, a study was carried out to improve upon the inhibition shown by 3, while simultaneously prioritizing a selectivity for PARP1 over PARP2. To achieve this objective, 3 was optimized by: (i) varying the piperazine linker surrogates and (ii) extending the structure into the adenine-binding pocket (ABP) using different heteroaromatic moieties including 5-(un)substituted benzimidazole ring. This work led to two promising compounds 10 (PARP1/2 IC50 = 19 nM / \u3e100 nM) and 11 (PARP1/2 IC50 = 12 nM / \u3e100 nM). Predicted binding models of the target compounds using the co-crystal structure of PARP1 provided further insights into the observed structure-activity relationships data
TEACHERS PERCEPTION OF STUDENT ENGAGEMENT USING FACE-TO-FACE AND REMOTE INSTRUCTIONAL METHODS
Get PDFThis phenomenology examines the instructional practices of high school teachers and the changes the challenges of remote learning during the COVID-19 pandemic have wrought, with a focus on strategies to promote student engagement. The more students are engaged, the more they may see the relevance of their experiences, feel connected to their school experiences, and develop more positive attitudes and attributes, both inside and outside of the school walls (Bridgeland, Dilulio, & Morison, 2006). Six big themes emerged through qualitative analysis were instructional strategies, adaptation to online learning, teaching practices post 2020, perceptions of the teachers, teacher-student relationships, and barriers to engagement. They used collaborative learning, scaffolding, active learning, and technology integration to make learning engaging. The pandemic has shifted the method of teaching to be more flexible and adaptive, using digital tools to maintain the interaction of students amidst challenges like distractions at home and the digital divide. Post-pandemic, educators adopted Blended Learning and Social-Emotional Support considering its importance and significance in engaging students. These findings contribute to redefined understandings of student engagement, including self-regulation, task completion, and social connection, for a fast-changing educational landscape and toward insights into resilient and inclusive pedagogical practices
THE ROLE OF COLLEGES OF PHARMACY IN STUDENT MENTAL HEALTH SUPPORT
Get PDFThe college journey is not easy, particularly within the pharmacy program— students undergo significant transitions that include meeting new rigor levels and pace in professional coursework, establishing new peers and faculty relationships, and coping with high stress levels (Choi et al., 2019). This qualitative case study will investigate how a pharmacy program and its associated resources relate to student mental health support and how pharmacy students perceive the importance of mental health initiatives in their academic program experience
Engaging Children with Learning Difficulties in a Book Club
Get PDFThis article examines the implementation of a before-school book club at a university laboratory school serving children with learning difficulties. The study highlights the role of intentional book selection and discussion in fostering empathy and a love of reading among diverse learners, particularly within special education contexts
Preservice Teachers as Active Decision-Makers in the Learning Process
Get PDFOne goal of a teacher education program is to facilitate the opportunity for preservice teachers to become adaptive and responsive to students\u27 needs. Thus, teacher education programs include field-based clinical experiences. The purpose of this article is to describe a qualitative study of 94 preservice teachers\u27 perspectives about their participation in an interactive field experience model, designed by the researcher/instructor, where they were the active decision-makers in the learning process of a young child. Social constructivist theories that situate learning as embedded in sociocultural environments framed this study and the interactive field experience model. Participants\u27 video and written reflections along with eight follow-up interviews were analyzed using thematic analysis to describe how the preservice teachers, with their own voices, relayed what they learned about teaching in a field experience model that seemed to foster the beginnings of adaptive and responsive teachers
GASTRONOMY AT THE HEART OF COMMUNICATION: A LOCUS OF HUMAN CONVIVIALITY
No full textThe significance of food over time is central to humanity and can aid in making people humane in a myriad of ways. This study seeks to (a) define the role of food in communication across sectors of global society and in the media realm (b) by analyzing a data set of all food related publications of the flagship magazine of UNESCO, The Courier, (c) through ethnographic study and inductive coding, I draw themes and trends that alter food communication from a multinational organization and pass the content through a theoretical lens and Large Language Model tool, to (d) illuminate implications in media of the poorest and most vulnerable in relation to food as requirement and pillar of life
THE PSYCHOMETRIC PROPERTIES OF A SPANISH VERSION OF THE ATTITUDES AND BELIEFS SCALE-2 SHORT FORM IN A MEXICAN SAMPLE
No full textThe Attitudes and Beliefs Scale 2-Short Form (ABS2-SF) is one of the most widely used measures of irrational and rational beliefs central to Rational Emotive Behavior Therapy (REBT). While evidence supports its reliability and validity in English-speaking populations, little is known about its applicability across cultural and linguistic groups. This study investigated the psychometric properties and cultural validity of the Spanish version of the ABS2-SF in a Mexican sample (n = 579) collected from undergraduate students in Tampico, Mexico, and compared them with English-speaking American non-clinical samples (n = 1,167). Using a bifactor multi-group confirmatory factor analysis (MG-CFA), I examined one general factor and eight specific factors reflecting irrational and rational forms of demandingness, frustration intolerance, awfulizing, and self-rating. Results demonstrated good model fit and supported configural, metric, scalar, and strict invariance, providing evidence that the ABS2-SF measures the same constructs across English and Spanish administrations. In addition, item response theory (IRT) analyses were conducted to evaluate the performance of the ABS2-SF at the item level. Differential item functioning (DIF) analyses revealed that all 24 items (12 irrational and 12 rational) displayed statistically significant DIF, indicating meaningful cultural-linguistic differences in endorsement patterns and item precision. Most irrational items were more difficult for U.S. participants to endorse, whereas rational items were generally more difficult for Mexican participants to endorse, with discrimination values typically stronger in the American group. These findings underscore the importance of considering cultural nuance when interpreting ABS2-SF scores and suggest potential item-level biases that require adaptation. Convergent and criterion validity analyses showed that irrational beliefs were consistently and positively associated with emotional distress across both groups, whereas rational beliefs demonstrated cultural variability: moderately protective in the U.S. sample but negligible in the Mexican sample. Together, these results suggest that irrational beliefs function as universal maladaptive processes, while rational beliefs are more culturally contingent. The findings highlight the value of IRT and DIF methods in cross-cultural validation and emphasize the need for culturally sensitive adaptations of REBT assessment tools
SUSTAINABILITY RISK IN GUYANA’S OIL SECTOR: AN ANALYTICAL FRAMEWORK FOR BALANCING ENVIRONMENTAL AND ECONOMIC IMPACTS
No full textThis study investigates the sustainability risks posed by Guyana’s rapidly expanding oil sector, with particular focus on balancing economic benefits against environmental vulnerabilities. The primary aim is to develop a Sustainability Risk Index (SRI) that captures the multidimensional impacts of offshore oil development using an integrated data-driven framework. Specifically, this thesis examines how emissions, biodiversity loss, oil spill exposure, economic volatility, and social development indicators interact to influence sustainability outcomes in the context of Guyana’s transition into a major petroleum-producing nation. The research does not involve human participants; instead, it draws on publicly available datasets collected from 2015 to 2024. These include environmental impact assessments (EIA) from ExxonMobil’s Uaru project, World Bank and IMF economic indicators, trade and health statistics from Guyana’s Bureau of Statistics, marine ecology surveys, rainfall and deforestation records, and satellite data. The data represents country-level and ecosystem-level observations focused on coastal and offshore regions most directly affected by petroleum activities. The methodology involves compiling and cleaning over 50 structured datasets into a master analytical file. Variables are categorized into environmental, economic, and social dimensions. A composite SRI equation is developed using weighted coefficients (b₀ to bₙ) for each subdimension, based on both empirical literature and exploratory statistical analysis. Supplementary regression and visualization tools within R Studio and Tableau are used to model trends, identify risk intensifiers, and simulate policy tradeoffs across various development scenarios. Comparative benchmarks from other petroleum-dependent economies are also used to contextualize Guyana’s trajectory. The significance of this study lies in its interdisciplinary, data-informed approach to sustainable development planning. The findings offer policymakers, nonprofits, and private sector stakeholders a quantifiable, dynamic tool to monitor and anticipate sustainability risks before they escalate into crises. Moreover, the framework provides a replicable model for other emerging oil economies seeking to avoid the pitfalls of the resource curse while maximizing long-term national benefit