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A novel Fibonacci hash method for protein family identification by using recurrent neural networks
No full textIdentification and classification of protein families are one of the most significant problem in bioinformatics and protein studies. It is essential to specify the family of a protein since proteins are highly used in smart drug therapies, protein functions, and, in some cases, phylogenetic trees. Some sequencing techniques provide researchers to identify the biological similarities of protein families and functions. Yet, determining these families with sequencing applications requires huge amount of time. Thus, a computer and artificial intelligence based classification system is needed to save time and avoid complexity in protein classification process. In order to designate the protein families with computer aided systems, protein sequences need to be converted to the numerical representations. In this paper, we provide a novel protein mapping method based on Fibonacci numbers and hashing table (FIBHASH). Each amino acid code is assigned to the Fibonacci numbers based on integer representations respectively. Later, these amino acid codes are inserted a hashing table with the size of 20 to be classified with recurrent neural networks. To determine the performance of the proposed mapping method, we used accuracy, f1-score, recall, precision, and AUC evaluation criteria. In addition, the results of evaluation metrics with other protein mapping techniques including EIIP, hydrophobicity, CPNR, Atchley factors, BLOSUM62, PAM250, binary one-hot encoding, and randomly encoded representations are compared. The proposed method showed a promising result with an accuracy of 92.77%, and 0.98 AUC score
Determining the impact of local people's perception of tourism on tourism support: Example of the TR21 Region
No full textYÖK Tez: 676366Bir bölgede turizmin gelişebilmesi için öncelikle önemli bir turizm paydaşı olan bölge yerel halkının duygularının, düşüncelerinin, görüşlerinin araştırılması ve incelenmesi gerekmektedir. Sağlıklı ve doğru bir turizm ortamından söz edebilmek için yerel halkın turizm kavramına karşı yaklaşımının öğrenilmesi ve turizme karşı oluşan algılarının ölçümlenmesi son derece önemlidir. Yerel halkın desteğinin olmadığı turizm faaliyetlerinin sürdürülebilir olması beklenmemektedir. Bu çalışmanın amacı TR21 Bölgesi sınırları içerisinde yaşayan yerel halkın turizm algısının belirlenmesi ve bu algının turizme verilen desteğe etkisinin olup olmadığının ortaya çıkarılmasıdır. Belirlenen amaç doğrultusunda nicel araştırma yöntemlerinden yararlanılarak ve anket uygulaması yapılarak, TR21 Bölgesi olarak adlandırılan bölgede veri toplanması ve analiz edilerek sonuca varılması hedeflenmiştir. Araştırma; turizmin ekonomik, kültürel, sosyal, çevresel ve toplam etkileri ile birlikte oluşan turizm algısının, turizme verilen destek üzerinde etkisinin olup olmadığını test etmektedir. Çalışmanın bir diğer amaç ve hedefi ise turizm algısı ve turizm desteği konularında literatüre katkı sağlamak, TR21 Bölgesi yerel halkının hangi şartlarda turizme destek verdiğini belirlemek ve bu şartların oluşmasında nelerin rol oynadığını ortaya koymaktır. Çalışma sonucunda bölgede bulunan şehirlerde, turizmin gelişmesine katkı sağlanması ve akademik literatüre fayda sağlanması beklenmektedir. Araştırma; TR21 Bölgesi (Tekirdağ, Edirne ve Kırklareli) içerisinde bulunan yerel halka uygulanmıştır. Araştırmanın saha ve anket çalışması 2020 yılının Ekim-Aralık aylarında 450 katılımcı ile gerçekleştirilmiştir. Örnekleme yöntemi olarak "kolayda örnekleme" yöntemi tercih edilmiştir. Araştırma için TR21 Bölgesi yerel halkından 450 anket toplanmış ve elde edilen 450 veri analiz edilmiştir. Araştırma verilerinin analizi SPSS (Statical Packages for the Social Sciences) 20.0 analiz programı kullanılarak yapılmıştır. Araştırmada demografik özelliklere ait frekans ve yüzde dağılım istatistikleri dışında, güvenilirlik ve geçerlilik analizleri (Reliability and Validity Analysis), normallik testi (Test of Normality), açıklayıcı faktör analizi (AFA), basit korelasyon analizi (Pearson Correlation Analysis), basit doğrusal regresyon analizi, bağımsız örneklem t-testi (Independent Sample tTest), iki ve üzeri kategorik değişkenlerin karşılaştırması için tek yönlü varyans analizi (One Way ANOVA) ve aralarında anlamlı ilişki bulunan grupların tespit edilebilmesi adına Tukey HSD (Post-Hoc Analysis) ikinci seviye testi yapılmıştır. Araştırma sonuçlarına göre hem turizm algısı hem de turizm desteği konularında yapılan hipotez testlerinde yerel halkın demografik özellikleri açısından anlamlı farklılıklar görülmüştür. Çalışma bulgularına göre TR21 Bölgesi yerel halkının turizm algısının, turizm desteği üzerinde pozitif yönde ve zayıf düzeyde anlamlı etkisi olduğu tespit edilmiştir. Çalışmanın sonunda TR21 Bölgesindeki turizm algısı değişkeninin, turizm desteği değişkeni üzerinde anlamlı bir etkiye sahip olduğu görülmüştür. Ayrıca araştırma bulgularına göre TR21 Bölgesi yerel halkının turizm algısını en çok etkileyen unsurların ekonomik ve kültürel etkiler olduğu ortaya çıkmıştır.In order for tourism to develop in a region, first of all, the feelings, thoughts and opinions of the local people of the region, which are an important tourism stakeholder, should be investigated and analyzed. In order to able to talk about a healthy and correct tourism environment, it is extremely important to learn the approach of the local people towards the concept of tourism and to measure their perceptions towards tourism. Tourism activities without the support of local people are not expected to be sustainable. The purpose of this study is to determine the tourism perception of the local people living within the borders of the TR21 Region and to reveal whether this perception has an effect on the support given to tourism. It is aimed to collect and analyze data in the region called TR21 Region by making use of quantitative research methods and conducting surveys in line with the determined purpose. The research tests whether the perception of tourism, which is formed with the economic, cultural, social, environmental and total effects of tourism, has an effect on the support given to tourism. Another aim and goal of the study is to contribute to the literature on tourism perception and tourism support, to determine the conditions under which the local people of the TR21 Region support tourism and to reveal what plays a role in the formation of these conditions. As a result of the study, it is expected to contribute to the development of tourism in the cities in the region and to benefit the academic literature. The research was applied to local people in the TR21 Region (Tekirdağ, Edirne and Kırklareli). The field and survey study of the research was carried out in October-December 2020 with 450 participants. Convenience sampling method was preferred as the sampling method. For the research, 450 questionnaires were collected from the local people of TR21 Region and 450 data obtained were analyzed. Analysis of the research data was made using the SPSS (Static Packages for the Social Sciences) 20.0 analysis program. Apart from the frequency and percentage distribution statistics of demographic features in the study, reliability and validity analysis (Reliability and Validity Analysis), Test of Normality, explanatory factor analysis (EFA), simple correlation analysis (Pearson Correlation Analysis), simple linear regression analysis , Independent Sample t-Test, one-way analysis of variance (One Way ANOVA) to compare two and above categorical variables, and Tukey HSD (Post-Hoc Analysis) second-level test to detect groups with significant relationships between them has been made. According to the results of the research, there were significant differences in terms of demographic characteristics of the local people in the hypothesis tests on both tourism perception and tourism support. According to the findings of the study, it was determined that the tourism perception of the local people of the TR21 Region has a positive and weak significant effect on tourism support. At the end of the study, it was seen that the tourism perception variable in the TR21 Region has a significant effect on the tourism support variable. In addition, according to the research findings, it has been revealed that the factors that most affect the tourism perception of the local people of TR21 Region are economic and cultural effects
Natural radioactivity measurements and evaluation of radiological hazards in sediment of Aliaa Bay, zmir (Turkey)
No full textThe activity concentration of natural Ra-226, Th-232, and K-40 radionuclides was examined in some selected locations in Aliaga Bay of Izmir district, Turkey. Sediment samples from 30 locations were collected and analyzed for radionuclides activity concentration by gamma-ray spectrometry using a high-purity germanium HPGe gamma-ray detector. The activity concentrations of the sediment samples range from 23.5 +/- 1.7 to 59.5 +/- 1.6 Bq kg(-1) for Ra-226, 37.5 +/- 0.9 to 64.4 +/- 0.6 Bq kg(-1) for Th-232, and 354.7 +/- 5.6 to 978.4 +/- 5.8 Bq kg(-1) for K-40. Based on the obtained results, the radiological parameters were evaluated. The mean values for absorbed dose rate, annual effective dose equivalent, radium equivalent activity, external hazard index, and excess lifetime cancer risk were determined and found as 81.64 nGy h(-1), 100.13 mu Sv y(-1), 173.31 Bq kg(-1), 0.47, and 0.40, respectively. Calculated radiological parameters of sediment samples were compared with the World Standard Value. The results obtained in this study were found to be above the globally standard limit for most locations. Statistical data such as skewness and kurtosis were calculated, and frequency distribution, Pearson's correlation analysis, box plot, factor analysis, and cluster analysis were applied in order to assess the distribution of radiological parameters and relationship between them
Heat Recovery From Textile Dyeing Waste Water: Real Busıness Example
No full textHızla gelişen teknoloji ve artan dünya nüfusu, insanların yaşam standartlarında değişikliklere yolaçmaktadır. Öte yandan dünya enerji kaynakları hızla azalmakta iken, buna karşılık enerji ihtiyacı sürekliartmaktadır. Enerji çoğu sektör için olduğu gibi, tekstil için de temel gider kalemlerinden biridir. Türkiyeekonomisi için, istihdam ve ihracat anlamında önemli bir yere sahip olan tekstil işletmeleri, gelişen rekabetşartlarına uyum sağlamak zorundadırlar. Bu yüzden de giderlerini ve özellikle enerji maliyetlerini azaltmakdurumundadırlar. Kaldı ki, birincil enerji kaynaklarında % 72,6 oranında dışa bağımlı olan Türkiye içinenerji verimliliği kaçınılmazdır. Tekstil terbiye işletmelerinde, boyarmaddelerle birlikte atık su karakteriniönemli ölçüde belirleyen çok sayıda kimyasal madde kullanılmaktadır. Birçoğu çevresel açıdan risk içerenbu maddeler, atık su ile birlikte bir sorun olarak karşımıza çıkmaktadır. Tekstil sanayiinde 1 ton ürünekarşılık 200 m3ile 350 m3 arasında atık su oluşumu söz konusudur. Bu çalışmada, Türkiye’deki gerçek birtekstil boyahanesinde oluşan atık suların ısısından yararlanarak, işletmeye giren temiz soğuk suyunısıtılması ile kazanılan ısı enerjisi incelenmiştir. Kazanılan enerji miktarı ve yatırımın geri ödemesi süresimatematiksel verilerle ortaya konularak, edinilen kazanımlar değerlendirilmiş ve önerilerde bulunulmuştur.Rapidly developing technology and increasing world population cause changes in people's living standards. On the other hand, while the world's energy resources are decreasing rapidly, the need for energy is constantly increasing. Energy is one of the main expense items for textiles as well as for most sectors. for Turkey's economy, the textile company which has an important place in terms of employment and exports, must adapt to the changing competitive conditions. Therefore, they have to reduce their expenses and especially energy costs. Moreover, 72.6% of which is dependent on foreign energy efficiency in primary energy sources for Turkey is inevitable. A large number of chemicals are used in textile finishing businesses, together with dyestuffs, that significantly determine the character of wastewater. These substances, many of which are environmentally risky, emerge as a problem with wastewater. In the textile industry, there is a wastewater generation between 200 m3 and 350 m3 for 1 ton of product. In this study, by utilizing the heat of the wastewater produced in a real textiles dye in Turkey, the heat energy recovered by heating the entity incoming fresh cold water was investigated. The amount of energy gained and the payback period of the investment are presented with mathematical data, the gains gained have been evaluated and recommendations have been made
An adaptive forecast combination approach based on meta intuitionistic fuzzy functions
No full textIntuitionistic meta fuzzy forecast combination functions are introduced in the paper. There are two challenges in the forecast combination literature, determining the optimum weights and the methods to combine. Although there are a few studies on determining the methods, there are numerous studies on determining the optimum weights of the forecasting methods. In this sense, the questions like What methods should we choose in the combination? and What combination function or the weights should we choose for the methods are handled in the proposed method. Thus, the first two contributions that the paper aims to propose are to obtain the optimum weights and the proper forecasting methods in combination functions by employing meta fuzzy functions (MFFs). MFFs are recently introduced for aggregating different methods on a specific topic. Although meta-analysis aims to combine the findings of different primary studies, MFFs aim to aggregate different methods based on their performances on a specific topic. Thus, forecasting is selected as the specific topic to propose a novel forecast combination approach inspired by MFFs in this study. Another contribution of the paper is to improve the performance of MFFs by employing intuitionistic fuzzy c-means. 14 meteorological datasets are used to evaluate the performance of the proposed method. Results showed that the proposed method can be a handy tool for dealing with forecasting problems. The outstanding performance of the proposed method is verified in terms of RMSE and MAPE
The Effect of Temperature on Wear Performance of High-Velocity Oxy-Fuel Sprayed WC-10Co-4Cr Coating on AA7075-T6 Substrate
No full textIn this study, the friction wear performance of a High-velocity oxy-fuel (HVOF) sprayed WC-10Co-4Cr coated AA7075-T6 substrate was investigated against a WC-4Co ball at different temperatures using a pin-on-disk tribometer. WC-10Co-4Cr coating was deposited with a commercial HVOF-K2 spray (GTV MF-HVOF-K 1000 compact), O-2 and kerosene as fuel gases with flow rates of 900 L/min and 26 L/h, respectively. Spraying was carried out with a rotation speed of 200 rpm, a particle feed rate of 1.8 rpm at a distance of 380 mm and a scanning distance of 5 mm. As HVOF spray, a commercial WC-10Co-4Cr powder (GTV 80.76.1.G) with a particle density of 4.63 g/cm(3) was utilized. The diffusion of coating to the substrate was investigated by scanning electron microscopy (SEM) and energy-dispersive x-ray spectroscopy (EDX). The hardness of the as-sprayed coating was measured using a micro Vickers hardness tester. The friction and wear tests were performed at a sliding speed of 100 mm/s for 1800 s under a fixed load of 3 N at 25, 100, 200 and 300 degrees C. The wear rate increased five times at 300 degrees C testing compared to room temperature (RT), but the average coefficient of friction (COF) value increased from 0.30 to 0.48 for 200 degrees C testing and then decreased to 0.36 for 300 degrees C. The powder and coating microstructures were analyzed using x-ray diffractometer (XRD) analysis. Morphological characterizations were accomplished by SEM and a wide field confocal microscope (WCM/profilometer), and wear mechanisms were examined. The wear mechanism was abrasive until 100 degrees C, but a temperature increase allowed for adhesive wear, plastic deformation and oxidation fatigue. Oxide layers and crack propagation took place in accordance with applied load and thermal expansion of the AA7075-T6 substrate. Oxide layers on the worn surface enabled the coefficient of friction to decrease after 200 degrees C. Oxide delamination and pile-ups were observed at 300 degrees C.Trakya University Scientific Research Projects Coordination UnitTrakya University [TUBAP 2019/248]; Kirklareli University Mechanical Engineering Department LaboratoryThe authors acknowledge the support of Trakya University Scientific Research Projects Coordination Unit under project number of TUBAP 2019/248 and Kirklareli University Mechanical Engineering Department Laboratory
The effectiveness of Glasgow-Blatchford Score in early risk assessment of hemodialysis patients
No full textIn the emergency departments (ED), the incidence of admission is increasing gradually due to gastrointestinal system (GIS) complications of hemodialysis (HD) patients. With this increasing number of patients, there are many classification systems developed in early risk assessment before endoscopy. In this study, we aimed to evaluate the Glasgow-Blatchford Score's (GBS) effectiveness in HD patients with suspected GIS hemorrhage in the ED.The files of 169 patients who received HD treatment were retrospectively reviewed. 64 patients who were examined and treated for reasons other than GIS hemorrhage in the ED were excluded, and the files of a total of 105 were analyzed retrospectively. The demographic characteristics and laboratory values of the patients were recorded from the patient files. When the patients were evaluated according to GBS parameters, a significant difference was found between the two groups in terms of pulse pressure, systolic blood pressure, hemoglobin value, melena, and accompanying comorbid diseases (p < 0.05). Of the 16 patients who presented to the ED due to syncope, 2 were in the GIS hemorrhage (+) group, and 14 patients were in the control group. In this study, we aimed to show that the increase in the number of admissions in the ED due to complications secondary to HD treatment and the accompanying serious changes in laboratory parameters may cause misleading results in patients with suspected GIS hemorrhage, and it is necessary to plan comprehensive and multi-center studies on new alternative scoring systems to GBS in specific patient groups such as HD patients
Burnout levels and sleep quality of COVID-19 heroes
No full textPurpose This study was carried out to determine the burnout levels and sleep quality of nurses in the coronavirus disease-2019 process. Design and Methods The population of this descriptive and cross-sectional study consisted of all nurses working in hospitals in Turkey. Findings Nurses' mean scores were compared by gender. The emotional burnout and personal achievement scores of male nurses were higher than those of female nurses. Single nurses had significantly higher emotional exhaustion and depersonalization scores than married individuals. Nurses mostly experienced emotional exhaustion, and burnout levels increased in line with insomnia. Implications for Nursing Practice Nurses struggling on the frontline during the pandemic were determined to be at risk of insomnia and burnout
MATTERS CONTAINING FEATURES IN ADMINISTRATIVE JURISDICTIONAL TAX PROCESS IN TURKEY
No full textKamu finansmanının öncelikli unsurlarından vergi, tarih boyunca toplumsal yaşamın aktif bir süjesi olmuştur. Bu özelliğinde dolayı vergi ekonomik, sosyal ve siyasi kapsamda etki alanı olan bir kavramdır. Toplumda tesir alanı son derece geniş karşılık bulan vergi ve doğal olarak vergilendirme sürecinin adalet çizgisinde gerçekleştirilmesi toplum ve devlet kurumu arasındaki ilişkilerin hukuki çerçevede sürdürülmesi açısından büyük önem arz etmektedir. Bu hassas dengenin sağlanması maksadıyla da kanun koyucu mükellef ile idare arasında vergilendirme süreci ve sonrasında ortaya çıkabilecek uyuşmazlıkları engellemek, idarenin kamu gücü çerçevesinde tek taraflı yaptığı işlem ve eylemlerin denetlenebilmesi için birtakım hukuki mekanizmalar geliştirmiştir. Vergilendirmeye muhatap olan kişiler bu süreçte oluşan hak ve menfaatlerini korumak adına söz konusu mekanizmalardan yararlanmaktadır. Adına yargısal denetim dediğimiz bu süreçte idarenin vergilendirme konusunda yaptığı işlem ve eylemler neticesinde ortaya çıkan uyuşmazlıklar hukuk devleti ilkesi kapsamında idari yargı konusu yapılmaktadır. Söz konusu uyuşmazlıklar, yürütmenin ve idarenin işlemlerinin hukuka uygunluğunu denetleyen idari yargı bünyesinde bulunan vergi mahkemeleri tarafından çözümlenmektedir. Bu aşamada mükelleflerin haklarını korumak adına vergi mahkemelerine intikal ettirdikleri vergi davaları, anlaşmazlıkların yargısal çerçevede çözümlenmesini sağlamaktadır. Vergi yargısı kapsamında tekemmül eden vergi davalarında bazı ayrıcalık barındıran durumlar ortaya çıkabilmektedir. Çalışmada bu minvalde vergi davası sürecinde özellik içeren hususlar incelenecektir.Tax, one of the primary elements of public finance, has been an active subject of social life throughout history. Due to this feature, tax is a concept that has an economic, social and political impact. Taxation, which has an extremely wide range of effects in the society, and naturally, the realization of the taxation process in line with justice is of great importance in terms of maintaining the relations between the society and the state institution in the legal framework. In order to ensure this delicate balance, the legislator has developed a number of legal mechanisms to prevent disputes that may arise between the taxpayer and the administration during and after the taxation process and to control the unilateral transactions and actions of the administration within the framework of public power. Persons who are involved in taxation benefit from the aforementioned mechanisms in order to protect their rights and interests created during this process. In this process, which we call judicial review, the disputes arising as a result of the procedures and actions of the administration regarding taxation are subject to administrative jurisdiction within the scope of the rule of law. The disputes in question are resolved by the tax courts within the administrative jurisdiction that inspect the lawfulness of the executive and administrative acts. At this stage, tax lawsuits brought by taxpayers to tax courts in order to protect their rights ensure that disputes are resolved in a judicial framework, and some peculiar situations may arise in tax cases that have evolved within the scope of tax jurisdiction. In this way, the specific issues in the tax case process will be examined in this study
NANOSCALE INFRARED INVESTIGATION OF ORGANICS IN CARBONACEOUS CHONDRITES
No full text[Abstract Not Available