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Youtube as a source of ınformation on public health ethics
No full textBackground: Public health ethics (PHE) is a dynamic area within bioethics that addresses the complex moral implications of public health measures in the face of growing health threats. YouTube is a powerful and widely used platform for disseminating health-related information. The primary objective of this study is to assess videos related to PHE on YouTube. The aim is to gauge the extent of misinformation in collecting PHE videos on the platform. Methods: On October 25, 2023, a thorough investigation on YouTube was undertaken, employing pre-determined search phrases involving ‘public health,’ ‘healthcare,’ ‘health services administration,’ and ‘health policy and ethics.’ The research encompassed a total of 137 videos that were selected according to strict inclusion and exclusion criteria. The videos were evaluated using the Global Quality Scale to measure quality and the modified DISCERN tool to evaluate reliability. The researchers identified video sources and compared several video attributes across different quality groups. Results: A total of 137 videos were analyzed, and 65 (47.45%) were classified as high quality, 52 (37.23%) as moderate quality, and 21 (15.32%) as low quality. In high-quality videos, academic, government, physician, and university-hospital sources predominated, whereas Internet users and news sources were connected with low-quality videos. Significant differences in DISCERN score, per day views, likes, and comments were seen across the quality groups (P = 0.001 for views per day and P = 0.001 for other characteristics). According to the findings, low-quality videos had higher median values for daily views, likes, and comments. Conclusion: Although nearly half of the videos were high-quality, low-quality videos attracted greater attention. Critical contributors to high-quality videos included academic, government, physician, and university-hospital sources. The findings highlight the importance of quality control methods on social media platforms and strategies to direct users to trustworthy health information. Authors should prioritize appropriate citations and evaluate YouTube and other comparable platforms for potential promotional low-quality information. © 2024 The Korean Academy of Medical Sciences
What did they say? What did they mean? Interpreting us policies through presidents' discourses at historical landmarks in Europe: a study of democracy attributes
No full textThis study investigates how US Presidents addressed the attributes of democracy in their speeches at critical European sites and historical breakpoints. The aim is to analyze the content of the speeches and determine whether there is a change in the emphasis on attributes related to the use of force. By examining projections related to force use, the study seeks to identify traces of US policies for the future of the Russian -Ukrainian War. Three speeches were selected for analysis: Reagan's (1987) and Clinton's (1994) Brandenburg's speeches, and Biden's (2022) Warsaw speech. They were analyzed using the attributes of global democracy indices through the Maxqda program. The findings indicate that the focused attributes of democracy and the overall comprehensiveness of attributes have changed over time. In summary, the analysis reveals that the frequency of the code 'force' in Clinton's and Reagan's speeches has shifted to the code 'power' in Biden's speech. This suggests that the potential military power for deterrence may be strengthened, yet it is not intended for physical deployment in the Russian -Ukrainian war as a means of force
?-Glucan Extraction from Hull-Less Barley by a Novel Approach: Microwave-Assisted Pressurized CO2/H2O
No full textΒ-glucans (BGs) are dietary fibers with human health benefits. Due to their emulsifying, thickening, and water-holding properties, they are frequently utilized in food formulations. Hull-less barley is one of the important sources of BGs. This research was performed to extract BGs from hull-less barley using microwave-assisted pressurized CO2/H2O (MW-PCO2) extraction, a combination that had never been employed before. The MW-PCO2 extraction conditions (temperature, time and water: barley flour ratio) were optimized using response surface methodology (RSM) with a Box-Behnken design for the maximum BG yield (%). Temperature of 47.74 °C, time of 19.92 min, and water: barley flour ratio of 10.10:1 (g/g) were found to be the optimum conditions for extraction with a BG yield of 62.43%. Additionally, MW-PCO2 extraction was compared with conventional water extraction (CE) and BG extracts obtained by both methods were characterized. Chemical composition, molecular weight, thermal properties, water solubility, water holding capacity, surface morphology, and Fourier Transform Infrared Spectrum (FTIR) of the BG extracts were determined. MW-PCO2 extraction gave higher BG yield and purity, molecular weight, and water holding capacity using less solvent in a shorter time. Furthermore, both extracts have similar morphological images, FTIR spectrum, and thermal properties. The results of this work demonstrate the potential of the MW-PCO2 approach for extracting BGs from hull-less barley with improved selectivity and recovery, which can then be added to a variety of food and drug formulations. © The Author(s) 2024
Correction to: a novel biallelic lck variant resulting in profound t-cell ımmune deficiency and review of the literature
Get PDFLymphocyte-specific protein tyrosine kinase (LCK) is an SRC-family kinase critical for initiation and propagation of T-cell antigen receptor (TCR) signaling through phosphorylation of TCR-associated CD3 chains and recruited downstream molecules. Until now, only one case of profound T-cell immune deficiency with complete LCK deficiency [1] caused by a biallelic missense mutation (c.1022T>C, p.L341P) and three cases of incomplete LCK deficiency [2] caused by a biallelic splice site mutation (c.188-2A>G) have been described. Additionally, deregulated LCK expression has been associated with genetically undefined immune deficiencies and hematological malignancies. Here, we describe the second case of complete LCK deficiency in a 6-month-old girl born to consanguineous parents presenting with profound T-cell immune deficiency. Whole exome sequencing (WES) revealed a novel pathogenic biallelic missense mutation in LCK (c.1393T>C, p.C465R), which led to the absence of LCK protein expression and phosphorylation, and a consecutive decrease in proximal TCR signaling. Loss of conventional CD4+ and CD8+ αβT-cells and homeostatic T-cell expansion was accompanied by increased γδT-cell and Treg percentages. Surface CD4 and CD8 co-receptor expression was reduced in the patient T-cells, while the heterozygous mother had impaired CD4 and CD8 surface expression to a lesser extent. We conclude that complete LCK deficiency is characterized by profound T-cell immune deficiency, reduced CD4 and CD8 surface expression, and a characteristic TCR signaling disorder. CD4 and CD8 surface expression may be of value for early detection of mono- and/or biallelic LCK deficiency. © 2023, The Author(s)
Validity and reliability of the Turkish version of the Canadian haemophilia outcomes-kids’ life assessment tool (the cho-klat)
Get PDFObjective: The evaluation of health-related quality of life (HRQoL) is encouraged to assess the multidimensional impact of treatments and disease and to improve care in boys with hemophilia (BwH). However, validated HRQoL tools for BwH are not yet available for Turkish. The purpose of this study was to assess the validity and reliability of the Canadian Hemophilia Outcomes-Kids’ Life Assessment Tool (CHO-KLAT), version 2.0, which is multilingual valid tool, in Turkish. Methods: The procedure included 4 steps: linguistic translation, content validity, validity evaluation with the Pediatric Quality of Life (PedsQL), finally test-retest analysis for reliability assessment. The participants were questioned for the type and severity of hemophilia, medical treatment, and inhibitor status. Results: The primary Turkish version of the CHO-KLAT evolved with the cooperation of the Canadian and Turkish teams. Content validity was performed with 9 experts and latest version of Turkish CHO-KLAT was produced. This multicenter study was conducted with 53 BwH aged 4-18 for validity assessment, 52 BwH for test-retest reliability. The mean age of BwH was 11.6 (standard deviation (SD): 4.2). The means of CHO-KLAT and PedsQL were 64.1 (SD: 4.2) and 66.7 (SD: 15.3). As a result of the validity evaluation, a strong correlation was found between CHO-KLAT and PedsQL (r = 0.603; P < .001). The interclass correlation coefficient was 0.887 in the test-retest reliability. Conclusion: The Turkish version of CHO-KLAT 2.0 was validated. It is now available to be used in clinical studies for HRQoL assessment of Turkish BwH
Hip-related functional limitations in individuals with idiopathic scoliosis: a controlled trial
No full textBackground: Since scoliosis is a three-dimensional deformity, it causes some movement limitations in the spine and related joints. However, functional limitations associated with scoliosis-related hip joint involvement are the subject of research. Aims: This study aims to investigate the physical characteristics and functional limitations associated with idiopathic scoliosis (IS), focusing on hip joint. Methods: Demographic characteristics, scoliosis-specific assessments and hip joint active range of motion (RoM), lumbar mobility (Modified Schober test), lumbopelvic stability (Single leg squat test-SLS), hip joint position sense, lower extremity balance (Y-balance test) and lower extremity functionality (Lower extremity functional scale-LEFS) were evaluated. Results: The study included 120 individuals, with 86 in the scoliosis group (mean age: 15.7 ± 3.4 years) and 34 in the control group (mean age: 16.1 ± 4.8 years). The scoliosis group exhibited limited RoM of the hip joint in flexion, extension, right abduction, adduction, internal rotation, and left external rotation compared to controls (p < 0.001). Lumbar mobility was decreased (p < 0.001). In the joint position sense test, the mean difference for right flexion was and for left flexion. Bilateral decreased SLS test performances (p < 0.001) and Y-balance test performance (p < 0.05) in individuals with IS. LEFS scores were statistically different but not clinically different between groups (p < 0.05). Conclusion: Individuals with IS show decreased hip mobility, lumbopelvic stability, hip joint position sense, and balance compared to healthy peers; however, these limitations do not have a clinical impact on daily living activities. © The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2024
Dış ticaret-çevre kirliliği ilişkisi: türkiye ekonomisi üzerinden analiz
Get PDFÇalışmada, Türkiye ekonomisi üzerinden dış ticaret ile çevre arasındaki ilişki 1960-2015 dönemi yıllık verileri ile incelenmektedir. Çevresel gösterge ekolojik ayak izi kullanılmaktadır. Dış ticaret göstergeleri olarak ise ihracat ithalat verileri modele dahil edilmiştir. Yapısal kırılmaya izin veren zaman serisi analizlerinin kullanıldığı çalışmada; Maki eşbütünleşme testine göre değişkenler arasında yapısal kırılmalar ile birlikte uzun dönemli ilişki görülmektedir. Zamanla Değişen Nedensellik Analizi sonuçlarına göre GDP’den ekolojik ayak izine doğru herhangi bir nedensellik ilişkisi yakalanmamış olup diğer tüm değişkenlerin bağımlı değişken olan ekolojik ayak izi ile belirtilen tarih aralıklarında çift yönlü nedensellik ilişkisi görülmüştür
Laktasyon dönemindeki annelere emzirme sırasında müzik eşliğinde doğal manzara resimleri kullanımının emzirme, emzirme memnuniyeti ve maternal bağlanma üzerine etkisi
Get PDFÇalışma, laktasyon dönemindeki annelere emzirme sırasında müzik eşliğinde doğal manzara resimleri kullanımının emzirme, emzirme memnuniyeti ve maternal bağlanma üzerine etkisinin değerlendirilmesi amacıyla randomize kontrollü bir çalışma olarak planlandı. Çalışmanın etik kurul izni alındı. Araştırma Aralık 2023 ve Ağustos 2024 tarihlerinde Adıyaman Üniversitesi 400 yataklı Eğitim ve Araştırma Hastanesi'nde bulunan Kadın Hastalıkları ve Doğum Kliniklerinde yürütüldü. Çalışmada gönüllü katılımcılar basit randomizasyon yöntemi ile müdahale gurubunda 45 ve kontrol grubunda 45 anne olacak şekilde iki gruba ayrıldı. Veriler Kişisel Bilgi Formu, LATCH Emzirme Tanılama ve Değerlendirme Ölçeği, Visual Analog Skala (VAS) ve Maternal Bağlanma Ölçeği kullanılarak toplandı. Verilerin analizinde Statistical Package for Social Sciences (SPSS) 25.0 yazılımı kullanılmıştır. Verilerin toplanması amacıyla çalışmaya katılan annelere ön test ve son test uygulandı. Kontrol grubundaki annelere ön test sonrası müdahale yapılmadı yanlızca çalışmaya katılan annelere primipar olması dolayısıyla emzirme eğitimi verildi ve 10 gün sonunda telefonla aranarak son test uygulandı. Müdahale grubundaki annelere ön test uygulandı, aynı şekilde emzirme eğitimi verildi ve sonrasında ilk gün hastane odasında ikinci gün ev ziyareti sırasında ve 8 gün boyunca da telefonla takip ederek toplamda 10 gün olacak şekilde müzik eşliğinde doğal manzara resimlerinden oluşan video emzirme sırasında anneye izletildi. Onuncu gün müdahale grubundaki annelere son test uygulandı. Müdahale sonrası son test puan ortalamaları incelendiğinde; LATCH son test puan ortalaması müdahale grubunda 8.24±1.65, kontrol grubunda ise 6.51±2.39; VAS son test puan ortalaması müdahale grubunda 5.73±1.68, kontrol grubunda ise 4.49±1.58; maternal bağlanma ölçeği son test puan ortalaması müdahale grubunda 103.18±1.84, kontrol grubunda ise 100.38±5.46 olduğu saptandı. Çalışmamızda sonuç olarak; annelere müzik eşliğinde doğal manzara resmimleri izlettirilmesinin annelerin emzirme, emzirme memnuniyeti ve maternal bağlanma düzeyleri üzerinde etkili bir yöntem olduğu belirlendi.The study was designed as a randomized controlled trial to evaluate the effects of using natural landscape images accompanied by music during breastfeeding on breastfeeding, breastfeeding satisfaction, and maternal attachment among lactating mothers. Ethics committee approval for the study was received. The research was conducted between December 2023 and August 2024 in the Obstetrics and Gynecology Clinics of the 400-bed Training and Research Hospital at Adıyaman University. Voluntary participants were divided into two groups using simple randomization, with 45 mothers in the intervention group and 45 in the control group. Data were collected using the Personal Information Form, LATCH Breastfeeding Assessment Tool, Visual Analog Scale (VAS), and Maternal Attachment Scale. Statistical Package for Social Sciences (SPSS) 25.0 software was used to analyze the data. Pre-tests and post-tests were administered to the participating mothers to gather data. In the control group, no intervention was applied after the pre-test; only breastfeeding education was provided due to the primiparous status of the participants, and a post-test was conducted via phone call after 10 days. In the intervention group, mothers received the pre-test, the same breastfeeding education, and were shown videos of natural landscape images accompanied by music during breastfeeding. This intervention was conducted in the hospital room on the first day, during a home visit on the second day, and followed up by phone for the next eight days, totaling 10 days. A post-test was administered on the tenth day. Upon examining the post-test mean scores, the LATCH post-test mean score was 8.24±1.65 in the intervention group and 6.51±2.39 in the control group; the VAS post-test mean score was 5.73±1.68 in the intervention group and 4.49±1.58 in the control group; the maternal attachment scale post-test mean score was 103.18±1.84 in the intervention group and 100.38±5.46 in the control group. In conclusion, our study determined that showing natural landscape images accompanied by music to mothers during breastfeeding is an effective method for improving breastfeeding, breastfeeding satisfaction, and maternal bonding levels
Evlilik doyumu ve baba katılımı ile baba-çocuk (12-36 ay) bağlanması arasındaki ilişkinin incelenmesi
Get PDFAraştırmanın amacı, 12-36 aylık çocukların baba-çocuk bağlanma güvenliği ile baba katılımı ve evlilik doyumu arasındaki ilişkinin incelenmesidir. Bu hedef doğrultusunda araştırmaya fiziksel ve psikolojik olarak sağlıklı 217 baba ve 12-36 aylık çocukları dahil edilmiştir. Araştırmada ölçme aracı olarak Demografik Bilgi Formu, Evlilik Doyum Ölçeği (EDÖ), Babaların Çocuk Bakımına Katılım Ölçeği (1-3 Yaş) Geliştirme Çalışması ve Bağlanma Davranışları Sınıflandırma Seti (BDDS) kullanılmıştır. Demografik Bilgi Formu, Evlilik Doyum Ölçeği, Babaların Çocuk Bakımına Katılım Ölçeği babalar tarafından doldurularak cevaplanmıştır. Bağlanma Davranışları Sınıflandırma Seti verileri ise; 121K470 numaralı Tübitak 1001 projesi kapsamında ev ziyaretleri yoluyla elde edilen video kayıtlarının puanlanması yoluyla elde edilmiştir. Bu doğrultuda değişkenler arası ilişkiyi incelemek için Spearman-Brown Sıralı Farklar korelasyon analizi ve değişkenlerin birbirini yordama durumunu ortaya koymak için çoklu doğrusal regresyon analizi yapılmıştır. Araştırmada, evlilik doyumu cinsellik alt boyutu ile babanın çocuk bakımına katılımı alt boyutları arasında pozitif yönlü düşük düzeyde anlamlı bir ilişki olduğu, evlilik doyumu değişkeninin diğer alt boyutları olan benlik ve aile ile baba katılımı alt boyutları arasında anlamlı ilişki olmadığı sonucuna ulaşılmıştır. Ayrıca evlilik doyumu ve babaların çocuk bakımına katılımı ile baba-çocuk bağlanma güvenliği arasında anlamlı ilişkinin olmadığı sonucuna ulaşılmıştır.The aim of the study is to examine the relationship between attachment security of children aged 12-36 months and father involvement and marital satisfaction. In line with this objective, 217 physically and psychologically healthy fathers and their 12-36 month-old children were included in the study. Demographic Information Form, Marital Satisfaction Scale (MSS), Fathers' Participation in Child Care Scale (1-3 Years) Development Study and Attachment Behavior Classification Set (BDDS) were used as measurement tools in the study. Demographic Information Form, Marital Satisfaction Scale, Fathers' Participation in Child Care Scale were filled out and answered by the fathers. Attachment Behavior Classification Set data were provided by the researchers' scoring as a result of video recordings conducted by the observation team within the project. In this direction, Spearman-Brown Sequential Differences correlation analysis was conducted to examine the relationship between the variables and multiple linear regression analysis was conducted to reveal the predictive status of the variables. In the study, it was concluded that there was a positive and low level significant relationship between the sexuality sub-dimension of marital satisfaction and the father's involvement in child care sub-dimensions, and that there was no significant relationship between the other sub-dimensions of the marital satisfaction variable, which are self and family, and father involvement sub-dimensions. It was also concluded that there was no significant relationship between marital satisfaction, father's involvement in child care, and father-child attachment security
The effect of oral and dental health status on the self-esteem levels of turkish university youth
Get PDFObjectives: This study aimed to investigate the impact of oral and dental health status on the self-esteem levels of Turkish university youth. Methods: This descriptive cross-sectional study included a sample of 962 Turkish university youth, aged 16 - 24, who met all the study criteria during the 2020 - 2021 academic year. Data were collected using a questionnaire and the Rosenberg Self-Esteem Scale (RSES). The data were analyzed with SPSS version 23.0. T-tests were used for pairwise comparisons, and one-way ANOVA was used for multiple comparisons. Results: Among the students who participated in the study, 56.7% were found to have high self-esteem, with a mean RSES score of 1.69 ± 1.62. Statistically significant differences were found between the RSES score and several factors, including decayed teeth (P < 0.01), presence of halitosis (P < 0.01), tooth color (P < 0.01), crooked teeth (P = 0.045), and toothache (P = 0.008). It was determined that dental crookedness, decayed teeth, bad breath, dark yellow teeth, the presence of tooth fillings, and extracted teeth were negatively associated with self-esteem. However, no statistically significant differences were found between selfesteem and factors such as the presence of tooth fillings, extracted teeth, tooth brushing habits, frequency of dental visits, or snack food consumption (P > 0.05). Conclusions: The results of this study reveal that poor oral care negatively impacts individuals' self-esteem. Issues related to oral and dental health, particularly concerning the appearance and condition of teeth, affect young people's relationships and self-confidence in social environments. It is crucial to develop family and school education programs, as well as national policies, particularly during childhood and university years, when attitudes toward oral and dental health are being established. © 2024, Yüzer Alsaç et al