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Biopsychosocial model-based exercise improves muscle strength, proprioception, pain, function, and quality of life in rheumatoid arthritis patients with knee involvement: a randomized controlled clinical tiral
This randomized controlled study aims to evaluate the effects of BETY (Bilişsel Egzersiz Terapi Yaklaşımı-Cognitive
Exercise Therapy Approach in English) as a biopsychosocial model-based exercise approach on knee joint proprioception
and other biopsychosocial characteristics through telerehabilitation in individuals with Rheumatoid Arthritis (RA). The
study included 19 female (10 Training Group, 9 Control Group) individuals diagnosed with RA. Individuals participated in
BETY group sessions via telerehabilitation for one hour, three days a week for three months. The primary outcome measures
were the BETY-Biopsychosocial Questionnaire (BETY-BQ) and Proprioception assessment via Biodex System III
Isokinetic Dynamometer and the secondary outcome measures were the McGill Pain Questionnaire- Short Form, Western
Ontario-Mcmaster University Osteoarthritis Index, Health Assessment Questionnaire, Falls Efficacy Scale, World Health
Organization Quality Of Life Scale-Short Form (WHOQOL-BREF), 6-Min Walk Test, Time Up And Go Test and 10-Step
Stair Climbing Test were used. There were no differences between the groups in terms of demographic characteristics.
Improvements were found in favor of the post-treatment training group in TUG, 10-SCT, 6MWT distance, BETY-BQ
sleep, WHOQOL-BREF social relations, knee proprioception, and muscle strength measurements (p < 0.05). In this study,
BETY was presented to the literature with its positive impact on muscle strength and proprioception, functional capacity,
pain, mood, quality of life, and biopsychosocial status in RA patients with knee involvement
Green Extraction Enhances Antioxidant and Cytotoxic Properties of Pomegranate By-Products Against Human Cancer Cell Lines
The aim of this study was to determine the anticancer effects of extract obtained from pomegranate by-products by green extraction (ultrafiltration and enzymatic extraction) (GE) on prostate (LNCaP), ovarian (A2780), breast (MCF-7), and colon (Caco-2) cancer cell lines compared to the traditional extraction (TE) and pomegranate juice (PJ). The GE sample demonstrated the highest total or individual phenolic content, and antioxidant activity. The major phenolics in all samples were determined to be ellagic acid, punicalagin A and punicalagin B. The 50% and 100% doses of the PJ exhibited a significant reduction in the viability of all cancer cells except LNCaP cells (only 100%) (p < 0.05). The TE sample showed a significant decrease in the viability of all cancer cells except the MCF-7 cell line (at all doses) at doses other than 1 M (p < 0.05). The GE sample caused a significant decrease in all cancer cells at all doses (1, 5, 25, 50, 100 and 150 M) (p < 0.05). Consequently, the GE sample applied with the green method was effective at all doses in reducing the viability of cancer cells
Longitudinal Associations Between Resilience, Emotion Regulation and Mental Health in Adolescents
The adolescent phase, which is already challenging, has been exacerbated by the psychological
impact and social restrictions imposed by the COVID-19 pandemic, leading to the
onset of psychiatric disorders. Strengthening psychological resilience (PR) and emotion
regulation (ER) during challenging periods is vital to foster protective factors and cultivating
effective coping strategies. This study aimed to longitudinally examine the association
between ER and PR in Turkish adolescents while considering mental health as a control
variable. Data collection took place twice, with an interval of three months, from December
2021 to March 2022, involving 929 students, comprising 465 girls and 464 boys, all
aged between 10 and 15 years (M = 12, SE = 0.92). The data were analyzed using SPSS
26.00 and MPlus 8.7. We performed an autoregressive cross-lagged analysis to investigate
the association between ER and PR. Our findings indicated that higher levels of PR were
positively associated with internal functional ER (ER-IF) and negatively associated with
internal dysfunctional ER (ER-ID) both at T1 and T2 cross-sectionally. Longitudinally,
baseline PR was positively associated with ER-IF three months later, without significant
gender differences. No longitudinal association was observed between PR and ER-ID.
Moreover, greater mental health problems at T1 were positively associated with T2 ER-ID
among women. Overall, our findings suggest that mental health professionals, teachers,
and others working with adolescents should incorporate practices that strengthen psychological
resilience to improve their well-being and quality of life
Determination of univariate, bivariate and conditional return periods of hydrological droughts using two-dimensional multivariate functions
Hydrological drought is frequently considered as the most intricate type of drought because of its long-term impacts, interactions with human activities and slow response of water systems to climatic fluctuations. Drought severity and duration are key parameters to characterize the drought. This research models the conditional probabilities, univariate, bivariate and conditional return periods of drought severity and duration using two-dimensional multivariate copulas functions. The analyses use streamflow drought index (SDI) and mean monthly streamflow records of 24 stations in Ye & scedil;il & imath;rmak Basin, Turkey for a 3-month time scale. Drought characteristics are derived from Yevjevic's Run Theory. The dependence between drought characteristics is examined with non-parametric Kendall's tau. The best marginal distributions of drought characteristics are selected among six types of distributions based on goodness of fit tests. The best copulas which have been utilized for the modelling of conditional probabilities, univariate, bivariate and conditional return periods are defined across 10 types of copula functions based on tail dependence and goodness of fit tests. Results have indicated a strong correlation between drought severity and duration. Marginal distributions of drought characteristics are modelled by Lognormal and Weibull distribution mostly. In most of the stations Gumbel copula has been detected as the best copula. Results have put forth that, many parts of the basin have the risk of hydrological drought under different conditions. Therefore, the basin needs an effective drought management plan
Çatışma ortamında işlenen suçlar: ABD'nin Afganistan müdahalesi sonrasında yasa dışı uyuşturucu ticareti
Bu çalışma, çatışma ortamında işlenen suçların boyutlarını Afganistan örneğinde incelemektedir. Özellikle 2001 sonrasında ABD’nin Afganistan müdahalesiyle ortaya çıkan güvensizlik ve siyasi istikrarsızlık ortamında yasa dışı uyuşturucu ticaretinin nasıl şekillendiği analiz edilmektedir. Çalışmada, Afganistan’daki uyuşturucu üretiminin ve ticaretinin küresel ölçekteki etkileri ortaya konulmaktadır. Müdahale öncesinde var olan ancak sınırlı düzeyde kalan uyuşturucu üretiminin, ABD müdahalesiyle birlikte artan yolsuzluk, zayıf devlet kapasitesi ve yerel güç odaklarının rekabeti sebebiyle nasıl hızla yaygınlaştığı gösterilmektedir. Ayrıca, uluslararası toplumun terörle mücadele önceliği içinde uyuşturucu ticaretine yeterince dikkat göstermemesinin, Afgan halkının geçim kaynakları açısından haşhaş ekimini daha cazip hale getirdiği vurgulanmaktadır.
Çalışma kapsamında Afganistan’ın tarihsel-siyasal yapısı ile uyuşturucu ekonomisinin birbirini nasıl beslediği ele alınmaktadır. Uyuşturucu kaçakçılığının yalnızca ekonomik bir boyutunun olmadığı, aynı zamanda güvenlik, insan hakları ve uluslararası ilişkiler bakımından çok boyutlu etkiler ürettiği tartışılmaktadır. ABD müdahalesinin başlıca hedefinin terörle mücadele olduğu, bu nedenle uyuşturucu sorununa yönelik politikaların bütüncül şekilde uygulanamadığı tespit edilmektedir. Saha verileri ve literatür taraması sonucunda ortaya çıkan bulgular, Afganistan’da kalıcı barış ve istikrar için yalnızca askeri yöntemlerin değil, ekonomik kalkınma ve kurumsallaşma çabalarının da gerekli olduğunu göstermektedir.
Çatışma ortamında işlenen suçlar konsepti çerçevesinde Afganistan örneği, uluslararası müdahalelerin uyuşturucu ticareti gibi yasa dışı faaliyetler üzerindeki etkisini anlamak bakımından önemli bir örnek teşkil etmektedir. Çalışma, bu çerçevede kapsamlı bir değerlendirme sunmaktadır.This study examines the dimensions of crimes committed in conflict environments by focusing on the case of Afghanistan. In particular, it analyzes how illicit drug trafficking has evolved amid the insecurity and political instability following the U.S. intervention in Afghanistan after 2001. The study presents the global impacts of drug production and trade in Afghanistan. It demonstrates how opium production, which was already present but somewhat limited before the intervention, rapidly expanded due to factors such as increased corruption, weak state capacity, and rivalry among local power centers following the U.S. intervention. Additionally, it emphasizes that the international community’s primary focus on counterterrorism led to inadequate attention to drug trafficking, making poppy cultivation more attractive for Afghans seeking livelihoods.
The study addresses how Afghanistan’s historical-political structure intersects with its drug economy, showing that illicit drug trafficking not only has an economic dimension but also generates multifaceted repercussions for security, human rights, and international relations. It is noted that the main goal of the U.S. intervention was counterterrorism, and thus anti-drug policies could not be applied in a holistic manner. Field data and literature review suggest that long-term peace and stability in Afghanistan require not only military interventions but also efforts toward economic development and institutionalization.
Consequently, within the framework of “crimes committed in conflict environments,” the case of Afghanistan stands as a critical example for understanding the influence of international interventions on illegal activities such as drug trafficking. The study offers a comprehensive assessment in this regard
The mediating role of attitudes in the effect of human and environment-centered value orientation on green cosmetic product purchasing behavior: Comparison of different countries
The growing concern for environmental issues has reached a critical level, demanding immediate attention. With the widespread integration of cosmetic products into daily routines, the escalating environmental impact cannot be ignored. Consumers are increasingly scrutinizing the environmental footprint of their purchases and the practices of manufacturing companies. To maintain their competitive edge, businesses must proactively understand and address the evolving needs and expectations of their consumers. This study aims to reveal the relationships between consumers’ environmental values, attitudes toward green products, and green cosmetics purchasing behaviors to guide decision-makers in the cosmetics industry. In addition, the study also evaluated the impact of consumers’ cultural backgrounds on their attitudes toward green products and their purchasing behaviors in the green cosmetics sector. We conducted a comprehensive online survey by collecting primary data from 883 respondents from 10 countries in Asia and Europe. Our analysis used partial least squares (PLS) with SMART PLS to comprehensively examine the interrelationships between variables. An ecocentric orientation positively influences attitudes and purchasing behavior toward green cosmetic products, while an anthropocentric orientation has a negative effect. Additionally, consumers’ attitudes mediate the impact of environmental attitudes on purchasing behavior and counteract the negative effect of anthropocentric attitudes. Cultural differences significantly impact consumers’ attitudes and purchasing behavior for green cosmetics. The study’s findings offer valuable insights for cosmetic companies dealing with growing demand for cosmetic products and environmental awareness. The empirical support for existing literature is significant, and the study’s structural model enriches the green cosmetics literature. It’s essential to consider both consumers and producers for sustainable green cosmetic production, ensuring profitability and encouragement for producers. © The Author(s) 2025
Investigating the effects of augmented reality-based interventions on pediatric patient outcomes in the clinical setting: A systematic review
Background and aim: Augmented reality (AR)-based interventions are increasingly being used in pediatric healthcare settings as non-pharmacological tools to reduce distress and improve patient outcomes. This review aimed to synthesize current evidence on the effectiveness, feasibility, and usability of AR interventions in improving physical, emotional, and psychological outcomes among pediatric patients. Methods: A comprehensive literature search was conducted across six databases-PubMed, Cochrane Library, MEDLINE, Scopus, Web of Science, and CINAHL-for studies published up to December 12, 2024. Eligible studies included those evaluating AR-based interventions with outcomes related to physical, emotional, or psychological health. Two reviewers independently conducted data extraction and assessed methodological quality using the Joanna Briggs Institute critical appraisal tools. The review followed the PRISMA 2020 guidelines and was registered in PROSPERO (ID: CRD42025638915). Results: The review included 14 studies involving 1057 children across diverse clinical settings such as surgery, oncology, dentistry, rehabilitation, and anesthesia induction. AR interventions were associated with reduced procedural pain and anxiety, improved cooperation and emotional comfort, increased knowledge acquisition, and enhanced satisfaction with care. Conclusion: AR-based interventions show significant promise in improving pediatric patient experiences and outcomes across a variety of healthcare domains. However, current evidence is limited by small sample sizes, methodological variability, and short-term evaluations. Implication to practice: AR-based interventions can enhance pediatric care by reducing pain and anxiety, improving cooperation, and increasing patient satisfaction. Their integration into clinical routines may support more positive healthcare experiences for children. (c) 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies
Structural Insights into Mock Theta-Function Identities via Multivariable R-Functions and Partition Theory
This paper introduces five new identities involving eighth-order mock theta functions, expressed in terms of multivariable R-functions. These identities are derived using the well-known qɩ-product identities in conjunction with the classical Jacobi triple product identity. The results establish profound links between theta function representations and combinatorial partition theory. Specifically, we present key findings that offer structural insight into mock theta function identities, using multivariate R-functions and partition theory. These discoveries uncover new patterns and identities within the framework of mock theta functions, with a particular focus on their multivariable structure and their connections to partition theory. In addition, we concisely summarize recent advancements in the field and discuss potential applications. The findings emphasize a significant relationship between our results and partition-theoretic identities. © 2025, Jangjeon Research Institute for Mathematical Sciences and Physics. All rights reserved
Insan & Toplum-The Journal Of Humanıty & Socıety
The aim of this research is to examine the achievements and challenges of the democratization process in Sub-Saharan Africa and to answer whether democratic progress is under threat. Focusing on Burkina Faso, Mali, and Niger-countries with regional and historical similarities-the research seeks to understand the common dy-namics of democratic development in these countries. The research employs a comparative framework to analyze their democratization processes. The findings of the research highlight two main conclusions: First, all the three countries have experienced a significant increase in voter participation, stronger public support for democracy and electoral processes and a notable opposition to one-man and one-party rule. Second, the democratization processes are frequently interrupted by military coups, authoritarian tendencies of leaders and electoral violence. While the research acknowledges the substantial progress made, it also emphasizes that significant challenges persist, which continues to weaken political institutions and processes. These challenges continue to hinder the full realization of democratic governance in these three countries and lead to regime changes
Seçilmiş Avrupa ülkeleri ve Türkiye'de tarımsal desteklerin büyüme üzerine etkisi
Tarımsal desteklerin ekonomik büyüme üzerine olan etkisinin araştırıldığı tez çalışmasında, 2006-2021 yılları arasında seçilmiş Avrupa ülkeleri (Avusturya, Belçika, Bulgaristan, Çekya, Almanya, Yunanistan, Macaristan, İrlanda, İtalya, Hollanda, Moldova, İspanya, İsviçre, İngiltere) ve Türkiye'de tarımsal desteklerin ekonomik büyüme üzerindeki etkisi yeni nesil panel veri analiz teknikleriyle test edilmiştir. Ekonomik büyüme ve ekonomik büyüme ile ilişkilendirilmiş makro büyüklükler konularında ulusal ve uluslararası birçok araştırmanın yapıldığı, buna karşın tarımsal destekler, kırsal nüfus ve tarımsal verimliliğin birlikte incelendiği az sayıda araştırma olduğu görülmüştür. Bu bakımdan tez çalışması, ulusal ve uluslararası az sayıdaki araştırmadan biri olması sebebiyle önem kazanmaktadır. Tez çalışması ile alan yazındaki eksikliğin giderilmesi amaçlanmaktadır. Elde edilen bulgularda, kırsal nüfustan tarımsal verimliliğe, tarımsal kredilerden ekonomik büyümeye, tarımsal verimlilikten tarımsal kredilere ve kırsal nüfustan tarımsal kredilere tek yönlü nedensellik ilişkisi olduğu tespit edilmiştir. Tarımsal kredilerden tarımsal verimliliğe doğru ise herhangi bir nedensellik ilişkisi görülmemiştir. Tarımsal desteklerin sağladığı finansal imkânların, verimliliği artırarak ekonomik büyümeyi hızlandırabileceği düşünülmektedir.This thesis examined the impact of agricultural subsidies on economic growth in selected European countries (Austria, Belgium, Bulgaria, Czech Republic, Germany, Greece, Hungary, Ireland, Italy, Netherlands, Moldova, Spain, Switzerland, United Kingdom) and Turkey between 2006 and 2021 using new generation panel data analysis techniques. It was found that there are many national and international studies on economic growth and macro-aggregates related to economic growth, but few studies that examine agricultural subsidies, rural population and agricultural productivity together. In this regard, this paper gains importance as it is one of the few national and international studies. This thesis aims to address the deficit in the literature. The results show that there is a unidirectional causality relationship from rural population to agricultural productivity, from agricultural credit to economic growth, from agricultural productivity to agricultural credit and from rural population to agricultural credit. There is no causal relationship between agricultural credit and agricultural productivity. It is assumed that the financial opportunities offered by agricultural subsidies can accelerate economic growth by increasing productivity