Albert Einstein College of Medicine, Yeshiva University: Open Journal Systems
Not a member yet
220 research outputs found
Sort by
Hippocrates Revisited
Get PDFA fundamental principle upon which the physician-patient relationship has come to rest is that of “primum non nocere,” translated from Latin to “first, do no harm.” It is often erroneously attributed to the Hippocratic Oath that graduating medical students swear by at more than 60% of United States medical schools (Tung and Organ, 2000), which actually lacks that phrasing, although it certainly acknowledges the principle of non-maleficence. Some sources attribute the Latin language of “primum non nocere” to the Roman physician Galen, c. 129–200 C.E. (Weitzel, 1996).
History and Hemolysis: Not an Easy Kidd’s Game and Review of Literature
Get PDFOne-third of delayed hemolytic transfusion reactions (DHTR) are mediated by the Kidd antibody. We report a case of Kidd-induced DHTR, detailing the diagnostic dilemma in a patient presenting with nonspecific symptoms and inconclusive data. The importance of a full history, including a transfusion history, is emphasized to overcome the dilemma and concludes with a literature review of Kidd (type anti-Jkb) antibodies.
Primary Care in Cuba
Get PDFThe Cuban health system surprises the international health community with strong health indicators despite economic hardship and international political tensions. This paper provides an analysis of the Cuban health system with a special focus on the role of primary care and primary care practitioners in Cuban culture. The paper also includes a discussion of Cuban health indicators, current epidemiological issues, national health initiatives, and the effects of Cuba’s political situation on its health care system
Treating HIV in the Bronx and Beyond: How the Center for AIDS Research at the Albert Einstein College of Medicine and Montefiore Medical Center is Working Toward the Future
Get PDFThis review provides a historical perspective on research performed at both the Albert Einstein College of Medicine (AECOM) and the Montefiore Medical Center (MMC). It discusses how the Center for AIDS Research (CFAR) has been an invaluable resource for the network of investigators at AECOM/MMC and it surveys the past and current HIV-related research projects in the Bronx and beyond.
Large Maf Transcription Factors: Cousins of AP-1 Proteins and Important Regulators of Cellular Differentiation
Get PDFA large number of mammalian transcription factors possess the evolutionary conserved basic and leucine zipper domain (bZIP). The basic domain interacts with DNA while the leucine zipper facilitates homo- and hetero- dimerization. These factors can be grouped into at least seven families: AP-1, ATF/CREB, CNC, C/EBP, Maf, PAR, and virus-encoded bZIPs. Here, we focus on a group of four large Maf proteins: MafA, MafB, c-Maf, and NRL. They act as key regulators of terminal differentiation in many tissues such as bone, brain, kidney, lens, pancreas, and retina, as well as in blood. The DNA-binding mechanism of large Mafs involves cooperation between the basic domain and an adjacent ancillary DNA-binding domain. Many genes regulated by Mafs during cellular differentiation use functional interactions between the Pax/Maf, Sox/Maf, and Ets/Maf promoter and enhancer modules. The prime examples are crystallin genes in lens and glucagon and insulin in pancreas. Novel roles for large Mafs emerged from studying generations of MafA and MafB knockouts and analysis of combined phenotypes in double or triple null mice. In addition, studies of this group of factors in invertebrates revealed the evolutionarily conserved function of these genes in the development of multicellular organisms
Your Practical Survival Guide to Surgical Internship
Get PDFThere is a lot of anxiety in medical school regarding internship, especially surgical internship. Internship is your introduction to medical responsibility. After four years of developing your interview and examination skills, as well as increasing your fund of medical knowledge, you are ready for real patients. Internship is easy if you are diligent and reliable. The anxiety over internship results from translating theoretical knowledge into practical skill, while “doing no harm.” Do not fear. It is not as hard as you think. Some sage words from my general surgery chief the day before internship sum it up: “Do what you are told; anticipate what you will be told; and, if you find yourself thinking ‘independently,’ call someone.” You know a lot as an intern! Use the team and the hospital to your advantage and your transition to responsibility will be easy. Maybe with these ten tips and tricks I found useful during my internship in your pocket, you can get some sleep as well
