The University of Kansas: Journals@KU
Not a member yet
    16504 research outputs found

    Exploring the roles of childhood trauma, psychological distress, and resource use in the context of a climate change-induced disaster

    Get PDF
    Aims: This cross-sectional study examined the relationship between childhood trauma and psychological distress (i.e., depression and anxiety symptoms) and the moderating role of resource use during and after the deadliest wildfire in California among a sample of college students. Methods: Participants (N = 473) completed well-validated measures six months after the 2018 Camp Fire exploring retrospective childhood trauma, current psychological distress, and resource use during and after the fire. Results: Multiple regression and moderation analyses revealed that greater exposure to childhood trauma predicted increased depression and anxiety symptoms following the fire. However, using community-based (off-campus) mental health services during and after the fire buffered the effects of childhood trauma on depression and anxiety symptoms. Conclusion: Youth exposed to childhood trauma are more susceptible to depression and anxiety symptoms post-disaster, yet using community-based mental health services may protect against the development of aggravated symptoms with greater childhood trauma

    On the Edge of America

    No full text

    Abstracts

    No full text

    Bariatric surgery as a potential trigger for worsening hereditary spastic paraparesis: Case report

    Get PDF
    We report a patient with c.1246C>T (p.R416C) heterozygous variant on the ATL1 gene causing a complicated form of hereditary spastic paraparesis (HSP) who had an early age of onset but had non-progressive disease until a rapid decline at age 57 after bariatric surgery. To our knowledge, there have been no studies or case reports documenting a trigger for clinical worsening in patients with HSP

    Dark Times for Public Health and Healthcare: Will the insurance industry fix itself?

    Get PDF

    T Cell Immunity in Pathogenesis, Progression, and Malignant Transformation of Endometriosis

    Get PDF
    Endometriosis is a common gynecological condition characterized by special features such as invasive growth, recurrence, and potential distant metastasis. Recent studies indicate an increasing incidence of malignant transformation of endometriosis. The mechanisms underlying the occurrence, progression, and malignancy of endometriosis are multifactorial, involving genetic alterations, environmental factors, hormonal imbalances, and immuno-inflammatory responses. Various T cell subsets play crucial roles in regulating immune responses and influencing disease progression and malignant risk. CD4+ T cells, including T helper (Th) cells (Th1, Th2, and Th17), regulatory T (Treg) cells, follicular helper T (Tfh) cells, and Th9 cells, alongside CD8+ T cells are essential for maintaining the immune microenvironment in endometriosis. Disruption of the balance among these T cell subtypes can promote chronic inflammation, immune evasion, and tissue remodeling that may facilitate malignant transformation. Therapeutic strategies targeting T cell function or restoring immune homeostasis hold promise for managing endometriosis through immunomodulation or checkpoint blockade therapy to prevent its malignant progression. This article reviews the role of T cells in the malignant transformation of endometriosis and proposes potential immunoregulatory treatment approaches

    Dis-Articulating Ideological Norms in Jamaican HIV Reporting

    Get PDF
    The use of accurate terminology reflecting the reality of Jamaica\u27s HIV situation is needed to dis/articulate existing social stigmas. This study explores whether Jamaican journalists predominantly use stereotypical language in HIV reporting. This quantitative case study used 14 predefined coding categories from PAHO\u27s 2006 HIV-related Language Update - a Caribbean HIV-reporting media guide. This facilitated the use of content analysis to evaluate HIV-related stories before and after the publication of PAHO\u27s HIV reporting guide in two time periods: January 1, 2004 to December 31, 2005, and January 1, 2007 to December 31, 2008. Jamaican journalists predominantly used 10 socially and medically problematic HIV-related terms. Through the application of the framing and agenda-setting theories, this study notes that these terms diminish attention from HIV; are socially outdated strategies; and ostracize, stereotype, and disrespect people with HIV. By spotlighting news production, this study underscores that dis/articulating existing stereotypical HIV reporting norms and language use in the Jamaican press must involve future research into newsroom dynamics

    12,388

    full texts

    16,504

    metadata records
    Updated in last 30 days.
    The University of Kansas: Journals@KU
    Access Repository Dashboard
    Do you manage Open Research Online? Become a CORE Member to access insider analytics, issue reports and manage access to outputs from your repository in the CORE Repository Dashboard! 👇