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    Nuclear Shadowing in inelastic photon-nucleus scattering in UPCs with forward neutrons

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    We argue that measurements of forward neutrons from nuclear breakup in inclusive high energy photon-nucleus (photon-A) scattering provide a novel complementary way to study small-x dynamics of QCD in heavy-ion ultraperipheral collisions (UPCs). Using the leading twist approach to nuclear shadowing, we calculate the distribution over the number of evaporation neutrons produced in photon-lead collisions at the LHC. We demonstrate that it allows one to determine the distribution over the number of wounded nucleons (inelastic collisions),  which constrains the mechanism of nuclear shadowing of nuclear parton distributions and gives an access to their impact parameter dependence

    Novel aspects of particle production in ultra-peripheral collisions

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    One of the hot topics in hadron physics is the study of the new exotic charmonium states and the determination of their internal structure. Another important topic is the study of the magnetic field produced in relativistic heavy-ion collisions and its effects on observables. In this note, we show that we can use ultra-peripheral collisions to address both topics. We compute the cross section for the production of the D⁺D⁻ molecular bound state in photon-photon collisions and also the cross section for π⁰ production in the target induced by the magnetic field of the projectile. Both cross sections are sizeable, and their measurement would be very useful to elucidate the above-mentioned questions

    UPC physics with ALICE in Run 3

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    The ALICE experiment has undergone a major detector upgrade for Run 3, expanding its detection capabilities for a wide variety of studies. The new continuous readout has significantly enhanced the physics potential for ultra-peripheral collision analyses. In this talk, we discussed some of the physics analyses that can be carried out in ultra-peripheral collisions using the Run 3 data and presented some of the first physics performance plots in both proton-proton and heavy-ion collisions

    The Safety and Protective Effects of Intravitreal Injection of Human Adipose-Derived Mesenchymal Stem Cells in a Rat Model of Retinal Ischemia/Reperfusion Injury

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    Purpose: The purpose of this study was to evaluate the safety and protective effects of intravitreal injection of human adipose-derived mesenchymal stem cells (ADMSCs) in a rat model of retinal ischemia/reperfusion (I/R) injury induced by anterior chamber perfusion.   Methods: Two weeks after induction of I/R injury, rats received a single intravitreal injection of human ADMSCs at doses of 2×10⁴ cells or 5×10⁴ cells suspended in 3 μL saline. Control rats received 3 μL saline or no injection. Retinal and optic nerve changes were assessed at two weeks after injection using immunofluorescence, hematoxylin and eosin staining, toluidine blue staining, and polymerase chain reaction to evaluate inflammation-related and neurotrophic factors.   Results: Intravitreal injection of human ADMSCs significantly reduced the number of apoptotic retinal ganglion cells after I/R injury, preserved the ganglion cell layer, and increased expression of neurotrophic factors such as brain-derived neurotrophic factor and insulin-like growth factor 1. The high-dose group (receiving 5×10⁴ cells) demonstrated superior neuroprotective effects compared to the low-dose group (receiving 2×10⁴ cells) as evidenced by less retinal ganglion cell apoptosis. In addition, histopathological analysis revealed localized tissue remodeling and increased microglial infiltration, particularly in the low-dose group.   Conclusion: The safety of intravitreal human adipose-derived mesenchymal stem cell transplantation requires further investigation, particularly with regard to potential proliferative responses and their long-term effects. In addition, the optimal dosage of adipose-derived mesenchymal stem cells needs to be explored to balance therapeutic efficacy and minimize adverse outcomes. which was associated with structural retinal damage. In addition, the high-dose group exhibited a potential risk of inflammation or maladaptive changes.

    Impact of Nanopore Flow Cell Types on DNA Methylation Detection

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    Third-generation sequencing technologies have revolutionized the study of epigenetic characteristics in human diseases, with Oxford Nanopore Technologies (ONT) at the forefront of long-read sequencing. ONT has made rapid improvements in flow cell designs, which greatly increased its sequencing accuracy but, at the same time, led to some projects utilizing different flow cell types, mainly R9 vs. R10, across samples. Whether and how the flow cell types affect genome-wide DNA methylation detection remains incompletely understood. Here, we used both flow cell types to analyze 6 human renal cell carcinoma (RCC) samples and compared the results. While there was a highly significant correlation between 5-methylcytosine (5mC) detected by R9 and R10 flow cells, we also observed substantial differences. R9 flow cells over-estimated 5mC levels at hypomethylated chromatin regions, mostly at promoters, while under-estimated 5mC at hypermethylated chromatin regions, enriched at intronic and intergenic regions. Such deviations in detection were likely caused by substantially lower sequencing accuracy of R9 flow cells, due to its mechanics, especially having problems sequencing homopolymeric DNA elements, such as CpG islands, leading to both higher false-positive and false-negative detections. Interestingly, such systematic errors were largely mitigated by batch-correction software, improving data comparability. In summary, our study reports superior performance of R10 flow cells, leading to much higher accuracy in base sequencing and DNA methylation detection

    Let It Flow, Let It Go: Sexuality, Gender Construction, and Worldmaking through Microteatro

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    Introduction to Special Issue on Worldmaking on Stage

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    A review of the nest-entrance lurkers of meliponine bees (Hymenoptera: Apidae)

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    Stingless bees (Tribe Meliponini) are a group of considerable biological, economic, and cultural value. Despite their significance, information about their natural enemies remains limited, particularly regarding animals that lurk at the hive entrances and prey on bees entering and exiting the colonies. This study reviews the literature documenting these interactions. A total of 15 publications were compiled, detailing 41 records of 33 different organisms acting as nest-entrance ambushers. In addition, the mantid Acontista cordillerae Saussure & Zehntner (Mantodea: Acanthopidae) is reported for the first time ambushing bees at nests of Scaptotrigona mexicana (Guérin-Meneville) in a meliponary in central Veracruz, Mexico. The dynamics among the ambush predators and other social bees are discussed, including their defense strategies and nest structures

    Analyzing the High School Athletic Administrator Role: Pressing Issues Facing the Position

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    In working to provide meaningful athletic programs that benefit student-athletes and other key stakeholders in the department (Grant, 2024; Martin et al., 2025), high school athletic administrators embrace substantial and wide-reaching responsibilities (Forsyth, 2024). As these demands continue to evolve (Fraina et al., 2021; Price et al., 2022), the role has become more complex and susceptible to negative experiences if not properly managed (Conant, 2017; Park and Curtner-Smith, 2018; Sullivan et al., 2014). Thus, the purpose of this study was to examine the most prominent issues specific to the athletic administrator role and their perceived importance for effectively fulfilling the position. With the support of the National Interscholastic Athletic Administrators Association (NIAAA), a survey was distributed to its national membership, ultimately securing 680 responses. A total of seven athletic administrator issues were analyzed and each rated as important by participants. One issue in particular (i.e., AD Responsibilities) was viewed as extremely important, with two issues (i.e., Providing ADs the Proper Tools to Manage and Relationship with Administration) deemed to be of very high importance. To pursue deeper meaning into these results, four interviews were then conducted with athletic administrators. This study offers key insight for practicing high school athletic administrators to understand the pressing issues impacting the position and their influence on one’s ability to lead an athletic department

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